The world seems to grow smaller every day. Fashion, food, entertainment—all are influenced by cultures around the globe. The same is true for health. Eastern approaches to holistic wellness, like Traditional Chinese Medicine (TCM), have crossed Western borders as health enthusiasts look for novel ideas for achieving optimal well-being.

The bright minds at USANA Health Sciences are leading the way into this uncharted territory with a pioneering study. The outcome of this research creates a new map for exploring ways to unite traditional Eastern philosophies with Western scientific practices.

USANA Science Summary

  • USANA researchers worked with experienced TCM practitioners to create a model for standardizing the diagnosis of a single TCM condition.
  • Using a multi-stage process, the team was able to develop a diagnostic protocol with better consistency than traditional methods.
  • The results of the study have two important impacts for the future of scientific discovery:
    • It provides a framework that may be used to help create diagnostic protocols for additional TCM conditions, which could help make care more consistent.
    • The process of designing the protocol can be copied and used to establish measurable data points for more clinical research studies. This will help advance the use of Western scientific methods to show the effectiveness of TCM.

Mixing TCM with Western thinking doesn’t come without some culture clashes. Western medicine usually relies on factors that can be measured and managed. TCM has focused on mental, physical, and spiritual forces that are often unseen but work together to create wellness as a whole.

People in Western cultures, which rely primarily on evidence-based science, may find it difficult to accept the positive impacts of TCM practices without the backing of measurable data. And designing studies that bridge the two cultures is a challenge.

But USANA scientists have shown it’s not impossible. This article summarizes a recent paper published in the European Journal of Integrative Medicine, which explores the groundbreaking work carried out by USANA’s research and development team.

This is important early research that could have far-reaching impacts on the field of TCM study. Approaches like those developed by USANA lay a path for Eastern or Western practitioners to make TCM recommendations grounded in clinically rigorous research. And to create a richer, more science-based holistic standard for total body wellness in every culture.

Setting a New Standard for TCM Practices

A visit to a Traditional Chinese Medicine (TCM) practitioner will often include four types of analysis: inspection, auscultation (listening to various organs), inquiry/questioning, and palpation (feeling with the fingers/hands). After considering all of these factors, a subjective diagnosis will be made.

The key word is subjective. The customary way someone is diagnosed with a TCM-related condition is based on the opinions of a single TCM practitioner. There are no objective measures used. And references to clinical studies or statistical analyses are rare.

Creating a more common criteria from which TCM practitioners can assess their clients would help ensure more consistent care. And for TCM practices to be measured scientifically, more objective methods that produce reliable, replicable, and non-biased results are needed.

There are many conditions and criteria considered by TCM practitioners. So, to begin creating an objective standard, USANA scientists first chose the condition to target with a new protocol: Protective Qi Deficiency (PQD).

Qi is a vital life force that flows through the body. There are several types, but protective qi is similar to innate immunity. It is considered a shield against evils. And deficiency of this type of qi is thought to predispose a person to invasion by pathogens.

Once researchers settled on PQD, they collected and defined potential factors associated with the condition to study. They started by reviewing published research, ancient TCM scriptures, and more modern TCM diagnostic guidelines. The researchers also consulted with TCM experts.

The list of PQD risks was eventually refined to 13 parameters. USANA researchers next developed an algorithm based on statistical models that included these parameters in an experimental protocol. Then they put the protocol to the test.

Studying an Eastern System with Western Science

USANA’s TCM study included a total of 207 participants, ages 18 to 65. They were broken into two separate groups. This was so researchers could first compile a data set that would narrow down the list of risk parameters to those truly significant in diagnosing PQD. Then the data from a second group was used to validate the final protocol for accuracy and consistency.

There were 151 participants in the first group. Every participant was examined by one of three highly trained TCM practitioners, each with 25+ years of experience. Each session consisted of two types of evaluation for PQD: a traditional and an experimental protocol.

Researchers used the data from group one to refine their initial PQD risk algorithm. The revised version was then assessed by an expert panel of six TCM practitioners from different geographic locations.

These practitioners were independent and not otherwise involved in the study. They were also unknown to each other. So, there was no opportunity for one practitioner to influence the opinions of the others.

Each independent practitioner returned their recommendations. And USANA researchers then modified the risk-scoring algorithm. Revisions continued until an acceptable level of agreement was reached by all.

The final algorithm was narrowed down from 13 to eight measures that played a major role in the diagnosis of Protective Qi Deficiency. They were as follows:

    1. Tongue appearance
    2. Voice strength (low voice and apathy)
    3. Cold frequency (how often the participant came down with a cold)
    4. Current or ongoing presence/absence of a cold
    5. Spontaneous sweating
    6. Aversion to wind or cold temperatures
    7. Overall pulse (three separate pulse points measured)
    8. Cun pulse (measurement from the pulse point closest to the wrist)

Each of the measures were weighted differently. The strongest predictors of PQD were found to be Cun pulse, cold frequency, or tongue appearance. However, diagnosis was less accurate if only one measure was examined. All eight needed to be considered to achieve the most consistent and accurate risk score for PQD.

Rigorous Research Pays Off with Enhanced Endpoints

The first phase of the study was completed and the scoring for the algorithm was refined. The next step in the process was using data from the second group of participants to validate it.

Fifty-six individuals were examined for PQD. This time, every participant was interviewed by all three Traditional Chinese Medicine practitioners (the same as those who examined group one). And once again, each session used two methods of evaluation: the traditional and experimental protocol.

The data from all of the sessions was cross-examined by USANA researchers and statistical models were applied to evaluate the accuracy of the PQD-risk score. They found the experimental scoring system’s ratio for correct predictions ranged from 94.2 to 98.2 percent. This indicates that the risk score was very accurate.

And it was repeatedly accurate.

Agreement can vary between TCM practitioners when diagnosing conditions using traditional methods. Ranges of agreement can go as low as 10 percent up to 60 percent. This means, between two practitioners, someone would receive a consistent diagnosis 10 to 60 percent of the time.

Agreement can increase up to 85 percent if the symptoms are discussed between practitioners ahead of time. However, USANA’s experimental risk scoring system was still superior.

When the TCM practitioners used the new algorithm, agreement among all three was 99.3 percent or greater. This outcome shows USANA’s scoring system results in a high degree of consistency when assessing PQD.

Accuracy and consistency are key. They’re necessary for creating more robust and relevant outcomes for those using TCM. And they’re also essential for aiding the scientific community in designing rigorous TCM-based clinical trials.

USANA Traditional Chinese Medicine Study Sets a New Path

Advancements in nutritional science requires trailblazers with innovative and creative ways of thinking. The USANA Traditional Chinese Medicine study marries Western approaches to research with Eastern approaches to well-being. It’s an exciting step in creating a new template for moving the science of holistic health and wellness forward. The study helps break down borders between past traditions and modern science, blazing a path to creating better, proven health outcomes for all.

https://www.sciencedirect.com/science/article/pii/S2225411016300955

https://www.hopkinsmedicine.org/health/wellness-and-prevention/chinese-medicine

Skincare isn’t always simple. From a pared-down cleanse-moisturize-protect routine to a 15-step Korean beauty regimen—and everything in-between—you may wonder what’s the best approach for you? Which skincare products are the best to counteract the look of aging? How do you know if your products will really work?

Look for the proof.

A 2019 clinical trial on USANA Celavive regimens revealed real beauty benefits when products were used as directed for about two months. Below, you’ll discover the impressive results of using advanced skincare that goes beyond what you see. And you’ll understand why the majority of women who completed the study wanted to keep using Celavive® Skincare after the trial ended.

USANA Science Summary

  • USANA sponsored an unpublished, single-center clinical trial to determine the results of using the Celavive regimens for eight weeks. Tests were administered at the Dallas Research Center by Thomas J. Stephens & Associates, Inc.—an independent research organization.
  • Participants were women with a median age of 50–51 from a range of races and ethnicities.
  • The women used the Celavive regimen recommended for their skin type—dry/sensitive or oily/combination—including treatment products and the Exfoliating Scrub+Mask.
  • Significant improvements were seen in both clinical and self-perceived measures related to visible aging. Noticeable results included reduced visible fine lines and wrinkles, diminished look of pigmentation, smoother texture, and increased radiance.

Many changes were noticeable in as little as four weeks. And more enhancements were seen after eight weeks. This progression demonstrates continued use of Celavive Skincare can help your skin look and feel increasingly refreshed, revitalized, and refined.

Celavive Clinical Trial Design

Fifty middle-aged women—from a range of backgrounds and with moderate facial photodamage—were selected to participate in the Celavive clinical trial. Photodamage was defined as the presence of fine lines, wrinkles, uneven pigmentation, or other common visible signs of aging.

Digital images (“before pictures”) were taken of the women’s faces, using a photo station specifically designed for skin analysis. Then 12 clinical assessments of their skin condition were taken to establish a baseline. Researchers also measured skin’s moisture levels using a Corneometer®—the instrument most widely used to determine hydration levels.

Beyond clinical measures, user perception was also evaluated. For this study, women answered a questionnaire to indicate their subjective opinion about 15 aspects of their skin’s condition.

Group Demographics

The women self-selected their skin type and were split into one of two equal-sized groups: the dry/sensitive group or oily/combination group. Then they followed the Celavive regimen recommended for their skin type—applying products twice a day, in the morning and evening.

Step AM PM
Cleanse Gentle Milk Cleanser

or

Creamy Foam Cleanser

 Gentle Milk Cleanser

or

Creamy Foam Cleanser

+

(3x/wk) [3 times per week]

Exfoliating Scrub+Mask
Tone Perfecting Toner Perfecting Toner
Enhance Vitalizing Serum

Hydrating Eye Essence

 Vitalizing Serum

Hydrating Eye Essence
Hydrate Protective Day Cream

or

Protective Day Lotion

 Replenishing Night Cream

or

Replenishing Night Gel

The women returned to the clinic for follow-up after using the Celavive products for four and eight weeks. Digital images and the same clinical measures were taken. And they completed the same subjective questionnaire. Additionally, participants answered questions about their experience using the products.

The results were largely positive and are summarized below.

Radiant Results Reflected in Clinical Measures

The look and feel of your skin changes with age. For the Celavive clinical trial, several aspects of normal skin aging were measured:

  • Number and depth of fine lines and wrinkles
  • Size and perceptibility of pores
  • Look and feel of skin’s texture
  • Luminosity or dullness
  • Evenness of skin tone
  • Level of discoloration
  • Skin sagging or tightness
  • Overall appearance of health

Statistically significant improvements in most clinical measures of visible skin aging were experienced in both groups by week four of using the Celavive regimens. And all parameters improved in both groups by week eight.

Clinical Grading Improvements at a Glance
Parameter

Dry/Sensitive

Regimen

 Oily/Combination

Regimen
Week 4 Week 8 Week 4 Week 8
Appearance of fine lines • • • •
Visible wrinkles (whole face) – • – •
Visible crow’s feet – • – •
Appearance of pores • • • •
Look of smoothness • • – •
Feel of smoothness • • • •
Softness to the touch • • • •
Radiance • • • •
Clarity • • • •
Skin tone evenness • • – •
Hyperpigmentation – • – •
Look of firmness • • • •
Overall appearance (healthy glow) • • • •
•     Indicates statistically significant improvement compared to baseline

–     Indicates no statistically significant change compared to baseline

No significant change was noted in Corneometer measures of skin hydration. However, there was an upward trend by week eight. (Celavive products provide topical moisture when applied daily. The lack of measurable change could be related to skin turnover rate, which slows with age—a longer study would be needed to confirm.)

Both groups experienced significant improvements in the clinical measures related to the look of aging. There were sizeable increases between weeks four and eight, indicating an increasing or cumulative effect over time. You can see the results for the dry/sensitive and oily/combination regimens below.

4- and 8-Week % Improvement: Dry/Sensitive Group

4- and 8-Week % Improvement: Oily/Combination

These results show that using the Celavive products together provides clinically measurable improvements in skin’s look and feel in a short amount of time. While this study only lasted for two months, there’s skin would likely continue to show even more visible enhancements when used long-term.

Participants Report Beautiful Benefits in Celavive Clinical Trial

Real-world results are the true test of your skincare routine. Women who participated in this trial provided firsthand reports of their experience with the Celavive regimens. Those who completed the study generally tolerated the products well. There were no serious reactions to the products, indicating that the products are generally safe for most skin types.

Most importantly, the assessments of product performance on their skin condition were nothing short of glowing.

After eight weeks, the majority of participants considered the look and feel of their complexion to be significantly better than before using the products. In fact, 80 percent of those using the oily/combination Celavive regimen and 84 percent of the dry/sensitive group reported improvements in how much they liked the overall appearance of their skin, even up close.

8-Week % Improvement on Self-Assessment of Skin Condition

When it came to a separate questionnaire on product performance, the participants’ ratings were also quite favorable at week eight.

Most notably, 80 percent of the oily/combination-regimen group said they liked using the products. With 72 percent saying they would buy and continue using Celavive (assuming a reasonable cost).

Similarly, 96 percent of the dry/sensitive-regimen group said they liked using the products. And 92 percent would buy and continue using Celavive.

The chart below illustrates the percentage of favorable responses to questions about various aspects of Celavive product performance.

8-Week % Favorable Responses on Product Performance

Ready to Get Glowing? Do Your Own Celavive Trial                     

The results of the Celavive clinical trial demonstrate the noticeable benefits of following the recommended regimen for your skin type. In as little as two months, you may see a more youthful-looking complexion—with fewer visible fine lines and wrinkles, a more even skin tone, and smoother texture. Not only will your complexion glow with the look of health, it will feel refreshed, soft, and soothed.

To conduct your own trial, simply determine your skin type and use the Celavive regimen that’s right for you. In two months, you’ll see the radiant results for yourself.

You’ve heard the argument before. “You can get all the nutrients you need from a healthy, whole-food diet.” Sure. Maybe in an ideal world. But nobody lives in an ideal world. Living in reality means admitting a supplement is an easy nutritional insurance plan. It’s a quick way to help ensure you consume the nutrition your cells need to thrive every day. *

Of course, all supplements aren’t created equal. A comprehensive-formula matters. Quality ingredients that are absorbed matters. Science also matters. That’s why USANA invested in a four-week, double-blind, placebo-controlled study to quantify the impact of taking the USANA® CellSentials™ for one month has on healthy adults.

The four-week CellSentials study found taking a full dose of Vita Antioxidant and Core Minerals twice a day improved a number of nutrition and health measures. This research shows daily supplementation is helpful for raising key nutrient levels in your body and supporting your well-being.*

USANA Science Summary

  • USANA published the results of a double-blind, placebo-controlled study conducted in 23 participants for four weeks.
  • Healthy adults, ages 23 to 43, took two tablets of Vita Antioxidant and two tablets of Core Minerals, twice a day.
  • Levels of vitamins B6, B12, folate, C, D, E, and K increased significantly.
  • Levels of superoxide dismutase (SOD), one of your body’s innate protective antioxidants, increased.
  • Support for healthy homocysteine and HDL cholesterol levels already within normal range was also observed.*

The results of the CellSentials study were published in the Journal of Functional Foods in 2019.

(This study revisits and expands upon findings from previously unpublished research that showed the supplement pair raised circulating serum nutrient levels.)

Let’s take a closer look at the findings.

CellSentials Study Shows Enhanced Status of Key Nutrients

Dietary surveys often show that people don’t eat enough of several key vitamins and minerals. Why is getting enough of these nutrients a big deal?

There are many health-related reasons you need a solid foundation of nutrition. But here’s one you may not have heard before: insufficient amounts of some nutrients in your body could lead to something called “hidden hunger.”

Hidden hunger is the phenomenon where people eat enough calories in a day but still don’t have adequate levels of certain nutrients in the body. So, their body signals them to eat more in an effort to top off low nutrient stores.

This invisible form of scarcity is especially common in those who lack diversity in food choices or who eat too much processed or nutritionally deficient food. Unfortunately, many inexpensive foods tend to be low in key nutrients, which is why low-income earners can be at higher risk for hidden hunger.

For the purpose of this study, USANA narrowed the focus to vitamins that are often insufficient in average diets. This includes vitamins A, C, D, E, and K, plus some B vitamins—B6, B12, and folate.

Participants fasted for 12 hours and blood was drawn to set baseline levels before the study began. Then fasted blood samples were drawn again at the end of the four weeks. There were significant increases in blood levels of seven of the eight vitamins:

  • Vitamin B6—plays important roles in energy metabolism and maintaining healthy homocysteine levels (an amino acid—more on this below)*.
  • Vitamin B12—supports energy, nerves, healthy blood cells, and DNA synthesis; also plays a role in folate metabolism.*
  • Folate (vitamin B9)—helps make genetic material and DNA and supports healthy cell growth and function; critical for women of childbearing age to support a baby’s healthy neural tube development in the earliest days of pregnancy.*
  • Vitamin C—provides antioxidant defense and is important for immunity, production of collagen (and other compounds), and use of iron in the body.*
  • Vitamin D—supports cell health, strong bones, immunity, and nerve and muscle function.*
  • Vitamin E—provides antioxidant defense and supports cognitive health as well as liver and immune function.*
  • Vitamin K—aids blood clotting along with bone, cardiovascular, liver, muscle, and cartilage health.*

Vitamin A was also measured. However, no significant change was observed. The reason is unclear. However, it could be due to the population studied: people already sufficient in vitamin A.

Your body maintains a fairly stable amount of vitamin A in plasma. It’s tightly controlled by the liver. So, changes may only have been seen if participants were deficient.

Maintaining sufficient vitamin A is important to support eye health (night vision), immunity, reproductive health, and gene expression.*

Increasing Your Innate Protective Antioxidants with InCelligence™

The CellSentials are more than a multivitamin. They also supply nutrients that can encourage your body to create its own powerful antioxidants. Amplifying your antioxidant levels is important, because the modern world is a free-radical-generating, cell-damaging jumble of junk foods, pollutants, and stresses. *

One way your body creates antioxidants is via the Nrf2 signaling pathway. Nrf2 is a chain of cellular reactions that’s activated when your body’s cells sense they need a boost in protection against free radicals. The InCelligence Complex in Vita Antioxidant includes several nutrients that can influence this pathway, including EGCG from green tea, curcumin, and resveratrol.

One protective antioxidant produced by Nrf2 activity is superoxide dismutase (SOD). This enzyme provides a first line of defense to help suppress the formation of free radicals in cells—stopping trouble before it starts.

Those who consumed the CellSentials in this study had elevated SOD activity after four weeks. This is evidence InCelligence Technology™ in the product works to enhance your body’s natural ability to protect itself from stresses. *

Increasing SOD is a good thing. Generally, as you age, your levels tend to go down. This increases your exposure to oxidative damage that can have adverse effects on your health. On the other hand, maintaining higher levels of SOD can help support healthy aging. *

As one of the most powerful antioxidant in the cell, SOD supports your health and well-being in many ways. It limits lipid peroxidation (when free radicals attack and damage fats) to help maintain healthy tissues throughout your body. Cognitive and immune function are protected by SOD. And it also has been shown to help maintain healthy carotid artery thickness to support cardiovascular function.*

Support for Cardiovascular Health Shown in CellSentials Study

Increased SOD isn’t the only way the CellSentials support the health of your cardiovascular system. Many micronutrients in the products are linked to maintained heart health:*

  • Zinc
  • Selenium
  • Magnesium
  • Vitamin C
  • Vitamin K

Many phytonutrients like lycopene and resveratrol have also shown cardiovascular health support. Plus, the added coenzyme Q10 in CellSentials helps your cells make the energy needed to keep your heart beating strong.*

Heart health is one of the top wellness concerns worldwide. So, the CellSentials study looked at a number of measures to see how one month of supplementation influenced cardiovascular function. Two positive results stood out: lower homocysteine and higher HDL levels.

Homocysteine is an amino acid (a building block of proteins). If you have too much in your body, it can damage endothelial cells. These cells help your blood vessels contract and relax for circulation. That’s why keeping homocysteine levels in a normal, healthy range is important for maintaining cardiovascular function. It’s also been linked to cognitive, mood, and bone health.*

Levels of homocysteine were lowered by 12 percent in CellSentials users, compared to a 1.26 percent difference in the placebo group. This could be due to the increase seen in B12 and folate levels. Both nutrients have been shown to help maintain healthy homocysteine levels. *

HDL cholesterol (the “good” kind) was also increased in the CellSentials group. HDL finds harmful cholesterol in your bloodstream and sends it to the liver for disposal. This is why optimal levels of HDL are linked to cardiovascular health. *

The increase in HDL shows the CellSentials are a heart-smart option for maintaining healthy cholesterol levels.*

The CellSentials Study is Science You Can Use

If you take a nutritional supplement for your health, sometimes it can be hard to notice a difference in how you feel on a daily basis. Supplements are made to help you maintain the healthy body you already have. So, you may not feel much different unless you are truly deficient in a given nutrient. *

The CellSentials study helps you see the effects of using USANA’s foundational nutritional supplement for only one month. Nutrient status improves. Innate antioxidant defenses are enhanced. And your cardiovascular health is protected. *

The USANA CellSentials are a great investment in your overall wellness. They’ll help you avoid hidden hungers and meet your nutritional needs for optimal health. Make Vita Antioxidant and Core Minerals your nutritional insurance plan. Take two of each, twice a day to help ensure your cells and your body will have what they need to thrive. *

https://lpi.oregonstate.edu/mic/glossary#homocysteine

https://lpi.oregonstate.edu/mic/vitamins/vitamin-B12

https://lpi.oregonstate.edu/mic/vitamins/vitamin-B6

https://www.ncbi.nlm.nih.gov/books/NBK222318/

https://lpi.oregonstate.edu/mic/vitamins/vitamin-A

https://ods.od.nih.gov/factsheets/VitaminA-Consumer/

https://www.jpeds.com/article/S0022-3476(12)00741-X/fulltext

https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/

https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969776/

https://www.sciencedirect.com/science/article/pii/S2090506817301550

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320919/

https://www.webmd.com/cholesterol-management/guide/hdl-cholesterol-the-good-cholesterol#1

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Celavive Exfoliating Scrub+Mask

Multitasking scrub and mask combination removes dead skin, dirt, and oil; refines complexion; and protects against the visible effects of pollution.

Get a Naturally Ageless Glow with Celavive® Exfoliating Scrub+Mask

Seeing a lifeless complexion when you look in the mirror can leave you feeling less than confident. Your skin could look dull if pollution from urban environments, lingering dirt, and dead surface cells build up. Eliminating the grime is the key to a radiant reflection. Now, the Celavive Exfoliating Scrub+Mask can help you take your complexion from lackluster to luminous in minutes.

The dual-action scrub and mask provides immediate and long-lasting benefits. It deep cleans and detoxifies after each use. And, it promotes healthy-looking skin by supporting cell turnover and defending against the visible effects of pollution. This helps reveal your ageless beauty in three ways:

  • Improves skin’s texture and minimizes the appearance of pores for a smooth, refined complexion
  • Reduces appearance of dark spots and discoloration for even skin tone
  • Visibly renews skin’s firmness for a naturally youthful-looking appearance

Exfoliating Scrub+Mask is safe for all skin types. Gentle hydrogel beads and charcoal help remove dirt, oil, and dead skin. At the same time, a unique mix of plant-based extracts, including the Olivol® Botanical Blend, revives radiance and shields your skin from the visible side effects of air pollution.

A few times a week, apply the Exfoliating Scrub+Mask to clean, dry skin and massage in circular motions. (You can add a little water if you’d like an even gentler scrub experience.) The product goes on dark grey and will lighten in color as you use it.

On busy days, you can scrub, rinse, and go. When you have more time, leave it on for 10 to 15 minutes for a purifying mask treatment. Rinsing will reveal skin that looks polished and vibrant and feels soft and refreshed.

After using Celavive Exfoliating Scrub+Mask, your skin will be free from any dead skin cells or impurities that might block absorption of your remaining skincare products. Follow with the rest of your Celavive treatment products and the moisturizer that’s right for your skin type.

Polish and Purify for Pore Perfection

Your face is covered with pores—two types, in fact. There are sweat ducts that excrete perspiration and toxins. And there are follicles, where hair comes through and most of your sebaceous glands are found. Sebaceous glands are responsible for producing sebum—an oily substance that hydrates and protects your skin.

Your pores play important roles in keeping your skin healthy. But they can become blocked with excess sebum, dirt, dead skin, or sweat. This can cause blackheads and also make your pores wider and more visible.

Fortunately, your skincare routine can help refine the appearance of your pores. Start by choosing non-comedogenic makeup and skincare products. That means they’re formulated with ingredients that won’t clog pores. It’s also important to cleanse your face in the morning and evening.

Exfoliating Scrub+Mask is a great addition to your pore-perfecting skincare routine. The dual-action power helps prevent clogs and make your pores less noticeable.

A Gentle Scrub That’s Safe for All Skin Types

Unlike some scrubs, you can use Exfoliating Scrub+Mask to regularly exfoliate dead, dry, flaky skin for a smoother, brighter appearance.

Other scrubs use harsh exfoliants like apricot kernel shells, which can cause microtears that may damage your skin barrier, leaving it vulnerable. The hydrogel beads in Exfoliating Scrub+Mask are extremely gentle and won’t damage or irritate skin. They’re made from a naturally pliable glucomannan fiber (from konjac root) coated with a soft gel.

The hydrogel beads are unique because they absorb excess oil and impurities and replenish moisture as they exfoliate. And, because they’re plant-based, they’re 100 percent biodegradable. So, the beads are gentle on your skin and kind to the planet (unlike scrubs that use plastic microbeads—which are now banned in the United States).

A Detoxifying Mask Deep Cleans

As a mask, the 2-in-1 formula of Exfoliating Scrub+Mask also pulls lingering impurities from deep within your pores to make them less visible.

Enlarged pores are a common skin complaint. And large pores aren’t only vexing. They’re also associated with more severe skin wrinkling, which can make you look prematurely older. Often, pores are stretched out when dirt or excess sebum is not sufficiently cleansed by regular face washing. A deeper clean is needed to maintain a refined appearance.

Charcoal is effective for detoxifying your pores to renew healthy-looking skin. It’s delivered along with a mineral-rich sea silt (a clay-like substance with fine particles) to nourish your skin as it purifies. Simply leave the mask on your face for up to 15 minutes. It will help pull excess oils, sebum, bacteria, or other impurities from your pores. When you’re done, you’ll see clear, clean skin that feels refreshed and energized.

Celavive Exfoliating Scrub+Mask delivers visible beauty benefits quickly. After only one use, skin analysis shows the look of less dead skin on the surface, increased smoothness, and smaller pore size.

Before

After

Regular Use Renews Your Naturally Ageless Glow

Using a scrub with gentle ingredients that won’t damage your delicate skin is one way Exfoliating Scrub+Mask helps protect your healthy glow. But it’s not the only way. Specialized ingredients in the product also revitalize a dull-looking complexion with hydrating extracts that support the skin’s natural renewal process.

Hydration is vital for a dewy, fresh-faced look. USANA’s Olivol Botanical Blend is included in the Exfoliating Scrub+Mask to infuse your skin with long-lasting moisture. The exclusive blend delivers 24 hours of hydration by helping your skin attract and hold water like a sponge. Restored moisture will leave your skin feeling soothed and refreshed after you rinse. And maintaining moisture is essential for keeping your skin barrier healthy, soft, and smooth.

Saccharide isomerate is another hydration helper that promotes renewed radiance. This natural sugar is isolated from a marine-sourced microorganism found on the shore of a river in France. It penetrates deeply to support your skin’s natural ability to replenish moisture and stay hydrated longer. The sugar also makes exfoliation with a scrub more effective by stimulating your skin’s natural renewal process.

Your skin has distinct layers. And over the course of about 28 days, cells move from the deepest layer all the way to the top, where they are shed. This turnover process is vital for maintaining healthy-looking skin. However, the process can work less effectively as you age. The slowdown is also influenced by other factors, including changes in hormone balance or nutrient deficiencies. If the dead skin cells on your face aren’t shed, it can cause your skin to look dull and prematurely older.

You can help loosen the dead, dry skin, so it’s removed more easily. When applied topically, the saccharide isomerate acts like a natural sugar in your skin that promotes cell turnover. It works to weaken the bond of dead skin cells that are ready to be shed with the healthy layer below.

By weakening the adhesion of the dead surface skin cells, this ingredient dramatically increases exfoliation. It offers similar action to alpha-hydroxy acids or other chemical exfoliants. But it is much gentler on skin and generally won’t cause sensitivity.

Replenishing moisture and supporting a healthy rate of cell turnover will help ensure a refreshed appearance as your skin renews itself. Dry flakes will be banished. And your complexion’s natural glow will increasingly shine through as you continue to use Exfoliating Scrub+Mask over time.

One study found after using saccharide isomerate for four weeks, skin appeared measurably smoother with pores less visible. And applying N-acetyl glucosamine (one of the two sugars that make up the ingredient) to the skin has also shown promise for reducing the look of dark spots or discoloration, improving the appearance of overall skin tone.

Celavive Exfoliating Scrub+Mask is Your Skin’s Pollution Solution

Your skin is constantly exposed to air pollution. And while the pollutants are usually invisible to the naked eye, exposure can eventually show up on your complexion.

Air pollution is all around you—inside and outside. Cars, industrial facilities, building materials, smoking, and even natural events like forest fires and volcanoes can release pollutants. Some of the most common sources are:

  • UV rays, especially when they interact with other compounds in the air
  • Compounds and small particles released from burning coal, oil, gasoline, trash, tobacco, and wood
  • Chemicals released from common items in your home or office, like solvents, paints, adhesives, cleaners, pesticides, and insect repellents

The World Health Organization reports nine out of 10 people around the world live where air quality exceeds guideline limits. Even some of the most advanced countries can still have pollution levels above quality targets. That’s bad news for your health and your skin.

Your skin barrier is the outermost layer of your skin that’s exposed to the environment. A strong barrier is vital for skin that looks healthy, hydrated, and youthful. It protects your skin’s vibrance by keeping toxins and allergens out and holding moisture in.

A 2017 review article summarized the effects repeated exposure to air pollution can have on your skin barrier. It reported that high levels of pollution can overwhelm your skin barrier’s natural defenses and cause excessive oxidative stress. Eventually, that stress can damage your skin’s integrity and balance.

A disrupted skin barrier spells trouble for your complexion:

  • Skin can become dry, sensitive, and irritated.
  • Dark spots or discoloration may appear.
  • Skin may start to look prematurely older, with visible sagging and wrinkles.

You can protect yourself from the pollution problem on two fronts. On the inside, you can support your skin’s defenses by eating a diet rich in antioxidants and essential nutrients, including B vitamins.

On the outside, you can defend your skin from pollution by shielding it with smart sun protection. And by applying targeted ingredients specifically designed to help block the visible effects of pollution.

The ingredients in Celavive Exfoliating Scrub+Mask are your skin-saving pollution solution.

In addition to the charcoal powder, which helps absorb surface-level pollutants, Camellia japonica flower extract offers distinct anti-pollution benefits. The hardy red flower is able to grow in the snow of its native Korea and Japan. It’s known by many names: rose of winter, Japanese camellia, Tsubaki, or DongBaek. The bloom is rich in protocatechuic acid—a potent polyphenol (a type of phytonutrient).

Camellia japonica extract supports a youthful look and feel by improving skin hydration and softness. It also offers excellent protective power with antioxidants that neutralize oxidative stress caused by exposure to pollution.

These protective powers have real, visible benefits. Free radicals generated by pollution can cause skin to look prematurely older. By reducing the visible effects of free radicals, Camellia japonica can help diminish the appearance of photoaging and maintain skin’s firmness.

Continued use will result in skin that looks and feels noticeably younger. Research conducted in a heavily polluted urban center in Korea revealed a significant reduction in the appearance of skin wrinkles after participants applied a lotion containing Camellia japonica for eight weeks.

Even in the face of heavy pollution, the Exfoliating Scrub+Mask will protect against the look of premature aging. It cleanses away dirt without stripping vital moisture, and banishes dry, dead skin for a flawless appearance. The mask and scrub also helps maintain skin’s visible firmness and elasticity.

Seeing a lifeless complexion reflected in the mirror is a thing of the past. You’ll love the way your skin looks when you use Celavive Exfoliating Scrub+Mask as part of your weekly skincare routine.

Key Ingredients

  • Olivol Botanical Blend
  • Glucomannan
  • Charcoal
  • Saccharide Isomerate
  • Camellia Japonica

See full list of ingredients

See glossary of Celavive Ingredients

Usage

Directions: Apply generously to face and neck in gentle, circular motions. Rinse thoroughly and pat dry. For deeper purifying benefits, leave on for 10–15 minutes before rinsing. For best results use 3–5 times per week.

Caution: Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children. Do not swallow.

Ideal For

  • All skin types

Frequently Asked Questions About Exfoliating Scrub+Mask

You will see immediate improvements in radiance, texture, and reduced dry skin after only one use. And the visible benefits of using Exfoliating Scrub+Mask will increase over time. Pores will continue to look more refined and skin will appear smoother after about one month of consistent use. You should also begin to notice reduced appearance of lines and wrinkles and less visible dark spots or discoloration after approximately two months, when used as directed.

For best results, use Exfoliating Scrub+Mask after cleansing and before using Perfecting Toner.

The Exfoliating Scrub+Mask tube and lid should be recyclable if disposed of according to requirements set by recycling facilities available in your area.

https://www.healthline.com/health/beauty-skin-care/charcoal-mask-benefits#benefits

https://intothegloss.com/2019/10/charcoal-in-beauty-products-explained/

https://share.upmc.com/2018/03/benefits-charcoal-face-mask/?vwo=social-pages_primary-nav

https://www.aad.org/skin-care-secrets/treat-large-pores

https://www.ncbi.nlm.nih.gov/pubmed/28195077

https://toxtown.nlm.nih.gov/chemicals-and-contaminants/polycyclic-aromatic-hydrocarbons-pahs

https://toxtown.nlm.nih.gov/chemicals-and-contaminants/volatile-organic-compounds-vocs

https://www.who.int/airpollution/en/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514578/

https://www.ncbi.nlm.nih.gov/pubmed/31389672

https://www.ncbi.nlm.nih.gov/pubmed/30691451

https://www.ncbi.nlm.nih.gov/pubmed/17386986

https://www.ncbi.nlm.nih.gov/pubmed/21731461

https://www.mdpi.com/2079-9284/5/1/19

https://www.ncbi.nlm.nih.gov/pubmed/26918966

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337418/

https://www.aad.org/skin-care-secrets/treat-large-pores

https://www.ncbi.nlm.nih.gov/pubmed/29393550

https://incidecoder.com/ingredients/saccharide-isomerate

https://www.ncbi.nlm.nih.gov/pubmed/17348991

https://www.ncbi.nlm.nih.gov/pubmed/19691938

https://www.stateofglobalair.org/sites/default/files/soga_2019_report.pdf

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The old adage “knowledge is power” has never been more relevant. In today’s knowledge economy, your cognitive function is one of the most valuable assets you have. Being able to learn, understand, and connect concepts is essential to creating the new ideas that drive success in the modern world. A recent CopaPrime+ study shows USANA’s unique cognitive-support supplement can help.*

The demand to keep learning so you can excel at daily mental tasks has led to a growing interest in brain-optimizing compounds known as “nootropics.” Individually, some of the most promising plant extracts for optimizing brain function have been American ginseng, bacopa monnieri, and coffee-fruit extract. These three nootropics are combined in USANA CopaPrime+.*

A new double-blind, placebo-controlled study assessed the effectiveness of the CopaPrime+ formula. And the results have been published (November 2019) in the journal Nutritional Neuroscience.

USANA Science Summary

  • USANA funded a double-blind, placebo-controlled research study, which was conducted by researchers from Central Queensland University and Deakin University in Australia.
  • Researchers looked at the acute (immediate) effects of consuming two tablets of CopaPrime+ on cognitive measures.
  • Participants were given a variety of scientifically validated tests before consuming CopaPrime+. They were then re-tested about 45 minutes later.
  • Those who took CopaPrime+ experienced an increase in mental efficiency and significantly improved accuracy and response times during cognitively demanding tasks.*

This is an exciting outcome that demonstrates combining three powerful nootropics in USANA’s CopaPrime+ formula is highly effective for supporting peak mental performance.*

Let’s take a closer look at the study.

CopaPrime+ Study Shows Support for Three Measures of Cognitive Function

A growing body of evidence supports the use of nootropics to aid healthy brain function. Researchers wanted to look at the effects of a combined formula. So, USANA provided CopaPrime+ to determine what effects could be expected from such a formula after a single dose. CopaPrime+ is a unique combination of American ginseng, bacopa monnieri, and coffee-fruit extracts.*

Forty healthy participants were enrolled in the study and randomized into a treatment or control group. They didn’t eat or drink (other than non-stimulating beverages) for two hours before the study. Upon arrival at the testing center, participants answered questions regarding their state-of-mind and had blood drawn to ensure healthy blood glucose levels. These measures were repeated four times during the two-hour study period.

The participants completed a variety of tests before taking two tablets of CopaPrime+ to establish a baseline. As they took the tests, images were taken of the activity in their prefrontal cortex—the part of the brain used for complex cognitive behavior and decision making. Then participants re-took the tests, with concurrent brain imaging, 45 minutes later.

After eliminating confounding factors, there were significant differences in the group supplemented with CopaPrime+ in three areas:

  1. Working memory and accuracy
  2. Speed of attention and response time
  3. Brain efficiency

Measuring Working Memory—A Key to Cognitive Performance

One of the tests in the study measured something called working memory. This is a type of short-term memory. It involves remembering a small amount of information for a short time and retaining it long enough to interact with it in some way. For example: when you read a sentence, you have to remember what came at the beginning, so that whatever comes at the end makes sense.

It seems simple. But the ability to put information together is critical for everyday life. Finding your car. Doing math in your head. Understanding a report at work. All of these tasks, and many more, rely on your working memory. This type of memory is important for decision making, problem solving, and reasoning. It is often associated with attention, completing tasks, and academic performance.

Working memory is tested using an N-back task. “N” stands for a number, which varies depending on the study protocol. The current study included 1-back, 2-back, and 3-back tasks.

Here’s how it works.

Participants are shown a sequence of letters one-by-one. Every time the test participant sees a sequence of letters, they need to indicate if the current sequence is the same as the one they saw “N” times ago.

This task used letters A to J, with a correct match appearing 25 percent of the time. Each sequence of letters was on-screen for 500 milliseconds (half of a second), with 1,500 milliseconds (1.5 seconds) between sets. The two-second total speed makes the N-back task considerably more cognitively demanding than if more time were allotted. (Try the N-back task for yourself.)

When participants saw a correct match, they pressed a spacebar on a keyboard. If they did not select an answer within two seconds, their answer was left blank.

Those who consumed CopaPrime+ improved on the 1-, 2-, and 3-back tasks in all measured criteria (time, accuracy, and error rate). The measures with the most statistical significance were the following:

  • Faster response times on the 2-back task
  • Greater accuracy on the 3-back task (fewer blank or incorrect answers overall)

The results indicate that CopaPrime+ offers positive benefits on working memory, which is related to many aspects of thinking and learning.*

Looking at CopaPrime+’s Effect on Attention

Researchers determined selective attention (the ability to select what you focus on) by employing one of the most well-known observations in psychology: the Stroop effect. The effect is easily understood when the task used to test it is explained.

The Stroop task asks people to look at color words. So, “red,” “blue,” “green,” etc. Sometimes that word is presented in the color it represents (e.g., the word “red” in red text). At other times, the word appears, but the color of the text is another color (e.g., the word “red” in green text). The Stroop effect is the difficulty people have when the word and color of the text don’t match up.

Participants in this study undertook two versions of the Stroop task:

  • In the “congruent” Stroop task, the words were presented in their corresponding colors (e.g., “red” in red).
  • In the “incongruent” Stroop task, words were never presented in the color that matched the text (e.g., “red” in green).

Thirty different word/color combinations were presented. Participants were asked to indicate what color the text was (not what it said). The words stayed on-screen until a key on the keyboard labeled with the color that matched the color of the text was selected. Researchers measured the time it took for a response. (You can try the Stroop task, too.)

Participants who consumed the supplement showed faster response times on the congruent Stroop task than the placebo group. So, this suggests CopaPrime+ may help you think and focus faster. *

Faster speed of attention is valuable for helping you be more effective during daily tasks. Being able to focus your attention swiftly and maintain accuracy will allow you to switch tasks with a lower time-cost. This could help you quickly ease into the flow of work and be less prone to distraction.

Studying Brain Efficiency to Help You Work Smarter

As participants took the tests in this study, their brain activity was imaged using functional near-infrared spectroscopy (fNIRS). This is a non-invasive method for looking at specific kinds of blood flow in targeted areas of the brain.

The participant wears a monitor on their forehead. And changes in blood flow are detected by measuring differences in infrared light (a form of light waves the human eye can’t see and that can pass through skin and bone). In simple terms, variances are caused by changes in how much oxygen is in the blood or in total blood volume.

A particular fNIRS measurement stood out in the study. During one of the most cognitively demanding tests—the 3-back task—researchers observed “reduced activation of the prefrontal cortex related to effortful mental demand” in those who consumed CopaPrime+.

At first, the above sentence may sound negative. Reduced activation in the brain doesn’t sound good! But in actuality, these changes in activity relate to the level of workload happening in the brain.

Having a workload that is too high (or too low) can cause a decline in cognitive performance. The reduced activation pattern observed in this study reflects a decrease in workload. Or, put another way, an increase in cognitive efficiency.

This means CopaPrime+ may help you maintain maximum mental function longer by helping the brain become more efficient.*

On a related note, a more efficient brain generally has better performance in working memory. So, the fNIRS results provide a glimpse into biological activity behind how CopaPrime+ might work to boost brain power. (This is an additional functional benefit beyond what is provided by the InCelligence Cognitive-Support Complex. The blend of bacopa and coffee-fruit targets cell-signaling pathways that optimize brain-derived neurotropic factor [BDNF]—a cognitive protein—in the brain.)

The CopaPrime+ Study is Science You Can Use

Life comes at you fast. And thanks to distractions coming from all sides, your brain has more demands on it than ever. The CopaPrime+ study shows the supplement can help you experience greater accuracy in your thinking and faster focus, with less of a drain on your mental capacity. *

And that’s after only one use. Research on the individual ingredients has demonstrated even greater benefits when used over time. So, add CopaPrime+ to your daily supplement routine. It’s scientifically shown to help you get the most out of your mental performance every day. *

https://www.scientificamerican.com/article/working-memory-how-you-keep-things-ldquo-in-mind-rdquo-over-the-short-term/

https://www.sciencedirect.com/topics/medicine-and-dentistry/working-memory

http://www.scholarpedia.org/article/Working_memory

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852635/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207727/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887505/

https://www.sciencedirect.com/topics/neuroscience/functional-near-infrared-spectroscopy

https://psychcentral.com/lib/what-is-functional-optical-brain-imaging/

https://www.frontiersin.org/articles/10.3389/fpsyt.2017.00154/full

https://journals.sagepub.com/doi/abs/10.1177/154193120004402121?journalCode=proe

 

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Safe, high-quality formulas backed by science make USANA products a smart choice. A parallel, randomized controlled study has added to the volume of scientific research that shows real health benefits when using USANA products.

In 2017, USANA funded a China Nutrimeal and Fibergy study. It was conducted on Chinese product formulas by researchers at the School of Public Health in Beijing, China. Two papers, co-authored by members of USANA’s scientific team, have been published on the study—one in the “Journal of Obesity” and the second in “Nutrition & Metabolism.”

USANA Science Summary

  • Overweight or obese individuals from the Beijing area replaced dinner with a USANA shake every day for 12 weeks. Each shake contained one serving of the Chinese formulas of Nutrimeal and Fibergy.
  • Weight decreased and improvements in body composition were observed in the meal-replacement group.
  • Measures associated with blood glucose levels and cardiovascular health either improved or were well-maintained in the meal-replacement group. (Results were more significant in men than women.)

China Nutrimeal and Fibergy Study Shows Support for Healthy Weight

Using meal replacements can be a simple, sensible way to lose weight. In fact, a systematic review and meta-analysis has shown programs that include meal replacements can lead to greater weight loss after one year than those that don’t.

Some diet types may not be so sensible. They might require replacing all or most meals. Or extreme calorie restriction. And while it’s possible to maintain this practice for a short time, a longer-term solution is needed to sustain weight loss. This was the reasoning behind the design of the China Nutrimeal and Fibergy study.

Researchers hypothesized replacing only one meal each day would be easier for the Chinese study participants to sustain. And it would cut enough calories to gradually add up to a meaningful change. So, they asked participants to replace dinner each day with a shake made from Chinese formulas of USANA Nutrimeal and Fibergy. Each shake contained 22.6 grams of protein, 11.1 grams of fat, 39.3 grams of carbohydrate, 20.9 grams of dietary fiber, and 388 calories.

Other than the daily shake, participants continued to eat the same as before.

After 12 weeks, 174 participants completed the study—91 percent of the original 192 who were included. This high percentage of completion demonstrates the intervention was sustainable for most people.

A number of body-composition measures were taken at the beginning and end of the study. Those who consumed the meal replacement shake for 12 weeks experienced the most significant improvements in the following (on average, results varied by individual):

  • Body weight, body mass index (BMI), and waist circumference each decreased by 4.3 percent
  • Body fat mass decreased 5.3 percent (7.7 percent in men, 3.2 percent in women)

Losing 4.3 percent of body weight in 12 weeks is a smart, safe rate of weight loss. Generally, those who lose weight gradually, but steadily, are more successful at keeping weight off. And even modest weight loss of five to 10 percent can mean big benefits.

Fat and Weight Loss Equal Health Gains

As noted above, Chinese participants in the 12-week China Nutrimeal and Fibergy study had meaningful reductions in waist circumference and body fat mass.

Reducing waist circumference and body fat, especially visceral fat (the fat in the abdomen), have both been strongly tied to maintained cardiovascular health. Waist circumference is important because it is an indicator of intra-abdominal fat—the fat that accumulates around organs. Too much intra-abdominal fat has been directly linked to cardiovascular risks.

The benefits of reduced body size were detectable. Researchers looked at the outcomes of 168 participants and found significant support for healthy blood pressure in men. Blood-pressure benefits were not as clear for women. One explanation for this difference could be the fact women maintained but didn’t lose as much visceral fat as men (among other possible reasons).

However, those results don’t mean the shakes weren’t beneficial for both genders.

The shakes made from the Chinese product formulas measurably helped Chinese participants maintain current levels of fat better than those in the control group. In fact, visceral fat increased in both genders in the control group (those who did not replace their meals) over the course of the 12 weeks. This indicates that drinking one shake each day helped men and women avoid fat gain.

Maintaining, not gaining, fat is helpful for preserving cardiovascular health and blood pressure.

Positive impacts on blood glucose were also seen in men and women who swapped their dinners with shakes made from the Chinese product formulas for three months. This reinforces positive results associated with weight loss and reductions in waist circumference that have been seen in other studies. Retaining normal blood glucose means the body can manage sugar properly, which is essential for maintaining long-term health and stable energy levels.

China Nutrimeal and Fibergy Study Demonstrates USANA’s Commitment to Science

USANA is dedicated to conducting thorough research that demonstrates the quality, safety, and efficacy of its products. The China Nutrimeal and Fibergy Study protocol was reviewed and approved by the Ethics Committee of Peking University Health Sciences Center.

The results of this study are encouraging. They suggest a way for overweight or obese Chinese individuals to manage their weight and support their health using Chinese formulas of USANA Nutrimeal and Fibergy. It is unclear if similar results would be seen in other populations with different formulas.

https://stanfordhealthcare.org/medical-conditions/healthy-living/obesity.html

http://www.myhealthywaist.org/evaluating-cmr/clinical-tools/waist-circumference-measurement-guidelines/waist-circumference/page/8/index.html

https://www.cdc.gov/healthyweight/losing_weight/index.html

A glossary with an alphabetical list of all the ingredients found in Celavive® Skincare products.

You can also read more in-depth information about each Celavive product, including more information about the ingredients. Links to each page are available here. 

0–9 | A–B | C–D | E–F | G–H | I–J | K–L | M–N | O–P | Q–R | S–T | U–V | W–X | Y–Z

0–9
1,2-HEXANEDIOL: Paraben- and formaldehyde-free preservative. Also an effective humectant (substance that attracts water) for dry skin.

A–B
ACANTHOPANAX SENTICOSUS (ELEUTHRO) ROOT EXTRACT: Part of a complex of three types of ginseng that provides antioxidant action for a brighter, firmer look.

ACETYL GLUCOSAMINE: Amino acid sugar that helps reduce the appearance of dark spots and unwanted variations in skin tone.

ACETYL HYDROXYPROLINE: Amino acid that adds moisture and supports the natural ceramides (part of your skin’s natural lipids) in the skin’s barrier for a hydrated appearance.

ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER: Gentle emulsifier that thickens lotions or creams to helps them glide on smoothly.

ALBIZIA JULIBRISSIN BARK EXTRACT: Also known as silk tree. Helps reduce the appearance of fine lines and loss of firmness.

ALPHA GLUCAN (see also DEXTRIN): Sugar that helps bind water to help moisturize and soften skin.

ALPINIA SPECIOSA LEAF EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS):  Botanical source of antioxidants that also conditions the skin.

AMINOMETHYL PROPANEDIOL: Blended with active compounds in skincare products to ensure they dissolve and absorb into skin properly.

ARTEMISIA ABROTANUM EXTRACT: Commonly known as southernwood extract, this compound is rich in oligosaccharides (a type of sugar) that make the skin appear smoother.

ASCOPHYLLUM NODOSUM EXTRACT: Seaweed that contains minerals and antioxidants to help nourish and deep clean your pores for a healthy appearance.

ASCORBIC ACID: Vitamin C is an antioxidant and skin-soothing agent that can help preserve formulations while providing support against the visible signs of environmental damage.

AVOBENZONE (see also UV FILTER BLEND): Sunscreen that protects primarily against UVA rays, but offers some protection against UVB.

BIS-GLYCERYL ASCORBATE: Non-ionic vitamin C derivative that provides excellent skin-moisturizing effects.

BLEND OF SEVEN BOTANICAL EXTRACTS (Paeonia Albiflora Root Extract, Paeonia Suffruticosa Root Extract, Lilium Candidum Bulb Extract, Origanum Majorana Leaf Extract, Alpina Speciosa Leaf Extract, Oenothera Biennis Seed Extract, Geranium Robertianum Extract): Unique blend of botanical extracts rich in antioxidants that contain essential oils to help preserve skincare products without the use of harsh chemicals.

BUTYLENE GLYCOL: Commonly used ingredient in cosmetics that helps to enhance the texture and application of skincare formulations.

BUTYROSPERMUM PARKII (Shea Butter): Known as Africa’s ancient beauty secret for its intense moisturizing capabilities and pleasant fragrance.

C–D
CAPRYLYL GLYCOL: A gentle moisturizer that also acts as a preservative.

CAPRYLIC/CAPRIC TRIGLYCERIDE: Compound derived from coconut oil and glycerin that adds moisture to skin.

CARBOMER: Helps suspend an insoluble solid in a liquid. Used to maintain product consistency by keeping emulsions from separating into their oil and liquid components.

CARRAGEENAN: Sugar extracted from certain species of red seaweed (Rodophyceae) that helps thicken and stabilize skincare formulas.

CELAVIVE CELL SIGNALING COMPLEX (made with InCelligence Technology®): Active ingredients that allow for effective cell communication—palmitoyl tripeptide-38, hexapeptide-48 HCL, southernwood extract, and coffee-seed extract. Supports your skin’s barrier system and enhances your body’s natural youth-preserving functions. Helps reduce the appearance of wrinkles, uneven skin tone, and large pores, while also producing a healthy glow.

CELLULOSE GUM: Helps thicken and stabilize skincare formulas.

CERAMIDE NP: Mimics natural ceramides to help skin retain moisture for a hydrated appearance.

CETEARYL ALCOHOL: Skin softener with conditioning benefits; used to improve the application and texture of skincare formulations.

CETETH-10: Emulsifier with dirt-dissolving properties that also helps active ingredients blend into a formula.

CETYL ETHYLHEXANOATE: Oil-like skin softener that helps dissolve dirt while preserving skin’s moisture.

CITRIC ACID: Alpha hydroxy acid derived from citrus fruits that serves as a natural preservative and pH (acidity) adjuster.

CITRULLUS LANATUS (Watermelon) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): One of nature’s few materials to contain citrulline, which helps condition the skin and lock in natural moisture.

CITRUS PARADISI (Grapefruit) FRUIT EXTRACT: Contains vitamin C and other antioxidants to promote an even, bright appearance.

COFFEE (Arabica) SEED EXTRACT(see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Plant-based ingredient that has advanced antioxidant properties and has been shown to contribute to smoother, healthy-looking skin.

CYCLODEXTRIN: Blends with pea protein to promote absorption into the skin.

CYCLOPENTASILOXANE: A skin-safe silicone fluid that enhances product texture and application.

DEXTRIN: Water-soluble carbohydrate used to improve formula texture. Helps lock in your skin’s natural moisture for a radiant look.

DICETYL PHOSPHATE: Enhances texture of skincare formulas while also conditioning skin.

DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE: Broad-spectrum UV filter that also helps stabilize other UV filters.

DIMETHICONE: Gentle, lightweight silicone that forms a protective hydrating layer on the skin to help retain natural moisture by preventing water loss.

DISODIUM EDTA: Preservative that protects integrity of active ingredients and maintains texture of formula.

DIPENTAERYTHRITYL TRI-POLYHYDROXYSTEARATE: Skin-conditioning liquid with excellent water-holding capability.

DIPHENYLSILOXY PHENYL TRIMETHICONE: Conditioning agent that enhances product texture and application on skin.

DIPROPYLENE GLYCOL: Stabilizes product texture.

DIISOPROPYL SEBACATE: Boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling hydrated and silky.

E–F
EPILOBIUM ANGUSTIFOLIUM FLOWER/LEAF/STEM EXTRACT: Brightens, balances, and provides antioxidant protection to the complexion.

ETHOXYDIGLYCOL: Supports effectiveness of UV absorbers.

ETHYLHEXYL PALMITATE: Gentle skin conditioner that enhances texture of skincare formulations without interfering with effectiveness of sunscreens.

FRAGRANCE: A combination of primarily botanical extracts that add a pleasant aroma to skincare products to enhance the overall experience.

G–H
GARDENIA FLORIDA EXTRACT: Flower extract with antioxidant properties that helps refresh and revive the look of dull, tired skin.

GERANIUM ROBERTIANUM EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Soothing botanical extract that helps support skin cells for a bright, youthful appearance.

GINKGO BILOBA LEAF EXTRACT: Contains high levels of the antioxidant quercetin, which plays a role in fortifying skin against environmental stress and visible aging.

GLUCOSYL CERAMIDE: Rice-derived ceramide that supports natural lipid production and moisture retention in the outermost layers of the skin, providing a healthy glow.

GLUCOSYL HESPERIDIN: Powerful phytonutrient from citrus plants that can help revitalize the look of dull, dry skin caused by stress and climate changes.

GLYCERIN: Preserves and attracts water in the skin’s outer layer for moisturizing effects that help skin maintain a healthy look and feel.

GLYCERYL STEARATE: Emulsifier that helps remove dirt and makeup while maintaining skin’s natural moisture.

GLYCERYLAMIDOETHYL METHACRYLATE/STEARYL METHACRYLATE COPOLYMER: Reduces the appearance of wrinkles by mimicking naturally produced ceramides, which are critical to the appearance of smooth skin texture and even tone.

GLYCINE SOJA (Soybean) SEED EXTRACT: Plant-derived ingredient that adds moisturizing benefits.

GLYCOL DISTEARATE: Pearlescent emulsifier and foaming agent that also helps condition the skin.

GLYCOSAMINE: An amino acid sugar that can help replenish moisture and soothe the skin.

GLYCOSYL TREHALOSE: Sugar that helps support ideal levels of skin moisture.

HELIANTHUS ANNUUS (Sunflower) OIL (see also HORUS K COMPLEX): Hydrating plant oil to give skin a youthful appearance.

HEXAPEPTIDES 9 AND 33: Hexapeptides 9 and 33 reduce the visual intensity of facial wrinkles.

HEXAPEPTIDE-48 HCL (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Hexapeptide-48 HCL counteracts the visible effects of chronological and lifestyle-stress aging by targeting a new category of skin receptors.

HIPPOPHAE RHAMNOIDES OIL: Also known as sea buckthorn oil. Rich in vitamin C, fatty acids, and powerful carotenoids to replenish skin’s hydration and defend against environmental elements.

HOMOSALATE (see also UV FILTER BLEND): Sunscreen that absorbs UVB rays.

HORUS K COMPLEX (Rosa Canina Fruit Oil, Avocado Oil, Apricot Oil, Sunflower Seed Oil): A blend of naturally derived plant and vegetable oils that are rich in vitamin K, which helps diminish the appearance of dark circles.

HYALURONIC ACID: Valuable skin-replenishing agent that has restorative abilities and can help enhance your skin’s natural moisture content for a noticeably plump appearance.

HYDROGENATED STARCH HYDROLYSATE: A hydrating sugar.

HYDROLYZED COLLAGEN: Consists of water-soluble peptides of various molecular weights that are rich in amino acids, which help support the natural production of a healthy skin matrix for a more youthful look.

HYDROLYZED CORN STARCH: Supports delivery of Olivol® Botanical Blend to skin and helps absorb oil.

HYDROLYZED HIBISCUS ESCULENTUS EXTRACT: Okra extract can help reduce the appearance of fine lines and wrinkles caused by repeated mechanical motions, like smiling.

HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER: Thickener that enhances consistency and stability of skincare formulations. Also gives product a silky feel on the skin.

HYDROXYPROPYL CYCLODEXTRIN: Helps provide stability to palmitoyl tripeptide-38.

I–J
ILLICIUM VERUM (Anise) FRUIT EXTRACT: Part of a botanical preservative system that also offers skin-conditioning benefits.

ISODECYL NEOPENTANOATE: Part of a blend of ingredients that boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling silky and supple.

ISOPENTYLDIOL: Helps attract and retain moisture for a hydrated appearance.

ISOPROPYL LAUROYL SARCOSINATE: Amino-acid from coconut fatty acids that offers non-greasy moisturizing for a hydrated look and smooth feel.

JOJOBA ESTERS: Oil-free skin softener derived from the desert plant jojoba that’s similar to sebum naturally found on skin. Promotes healthy appearance and even skin tone by increasing moisture; supporting skin barrier function; and reducing dryness and roughness.

K–L
LACTOBACILLUS/GRAPE JUICE FERMENT FILTRATE: Moisturizer with natural skin-conditioning properties.

LACTOBACILLUS/SOYBEAN EXTRACT FERMENT FILTRATE: Gentle skin-conditioning agent that contributes to a balanced, healthy-looking complexion.

LAURIC ACID: Moisturizing fatty acid found in coconut oil that offers gentle cleansing properties.

LAURYL LACTATE: Part of a blend of ingredients that boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling silky and hydrated.

LAURYL PCA: Moisturizer that helps condition the skin.

LECITHIN: Combines with sea buckthorn oil to enhance penetration and promote a healthy appearance.

LENS ESCULENTA (Lentil) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Plant-based ingredient that helps enhance moisture content in the skin for a long-lasting, hydrated look and feel.

LILIUM CANDIDUM BULB EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Extract from the bulb of the white Madonna lily that helps brighten and hydrate complexion.

LINALOOL: Natural fragrance.

LONICERA JAPONICA (Honeysuckle) FLOWER EXTRACT: Part of a botanical preservative system that also helps condition the skin.

M–N
MACADAMIA TERNIFOLIA SEED OIL: Contains high concentrations of palmitoleic acid, which helps increase hydration and plump the appearance of the skin.

MALIC ACID: Alpha hydroxy acid used in skincare formulations to promote healthy skin renewal for smoother-looking texture. Also helps balance the formula’s pH levels.

MALLOW FLOWER EXTRACT: Enhances texture and helps add moisture to soothe dry skin.

MANNITOL: Naturally derived sugar alcohol that serves as an effective skin conditioner by helping to reduce the loss of moisture.

MALPIGHIA PUNICIFOLIA (Acerola) FRUIT EXTRACT: Powerful antioxidant and added source of vitamin C.

MELISSA OFFICINALIS LEAF EXTRACT: Lemon balm extract that helps gently cleanse the skin. Also has antioxidant properties.

MENTHYL PCA: Skin conditioner with a cooling sensation to soothe the skin.

METHYL METHACRYLATE CROSSPOLYMER: Texture enhancer that also absorbs oil.

METHYLPROPANEDIOL: Helps enhance absorption of active ingredients and leaves a smooth, dewy finish on the skin.

MICA: Boosts effectiveness of sunscreens by helping them spread evenly for consistent coverage.

MYRISTIC ACID: Saturated fatty acid that creates lather or foaming effects for gentle cleansing.

NATTO GUM: Added to HORUS K COMPLEX. A fermentation product of soy that is a hydrating source of vitamin K.

O–P
OCIMUM BASILICUM HAIRY ROOT CULTURE EXTRACT: Antioxidant that supports your skin’s natural defense against the visible signs of aging caused by overexposure to the sun.

OCTINOXATE (see also UV FILTER BLEND): Sunscreen that absorbs UVB rays.

OCTOCRYLENE (see also UV FILTER BLEND): Moisturizing sunscreen that absorbs UVB light and also helps stabilize Avobenzone, which can degrade in light, over time.

OENOTHERA BIENNIS SEED EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Evening primrose seed extract that has brightening properties.

OLEA EUROPAEA (Olive) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Antioxidant that helps protect skin from environmental elements to maintain healthy appearance.

OLIGOPEPTIDE-6: Powerful peptide that helps to reduce the appearance of deep wrinkles and minimize the look of dark spots for a visible improvement in the appearance of aging.

OLIVOL™ BOTANICAL BLEND: Combines Olivol® olive-fruit extract with watermelon, apple, and lentil-fruit extracts to provide intense moisturizing effects that have been shown to increase the moisture level of the skin for up to 24 hours after just one application.

ORIGANUM MAJORANA LEAF EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Natural fragrance with preservative action.

PAEONIA ALBIFLORA & SUFFRUTICOSA ROOT EXTRACTS (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Help protect and brighten the skin’s appearance.

PALMITIC ACID: Fatty acid found naturally in the skin that is often used in skincare products as a cleansing agent and moisturizer.

PALMITOYL TRIPEPTIDE-5: Delivers moisture and nutrients that absorb deeply into skin. Enhances the natural production of collagen and elastin, which helps firm the appearance of sagging skin and diminish the visibility of wrinkles.

PALMITOYL TRIPEPTIDE-38 (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. It works to support the natural production of key healthy skin elements, like collagen and elastin, to promote younger-looking skin.

PANAX GINSENG ROOT EXTRACT: Part of a complex of three types of ginseng that helps improve the appearance of aging by energizing and protecting skin from the signs of visible photo-damage.

PANAX QUINQUEFOLIUS ROOT EXTRACT: Part of a complex of three types of ginseng that provide antioxidant, brightening, and firming action.

PANTHENOL: Form of vitamin B5 that softens skin.

PEARL POWDER: Rich in amino acids and minerals that help support skin hydration and protect against visible signs of environmental stress.

PEG-7 GLYCERYL COCOATE: Coconut-based ingredient used in foaming cleansers to enhance texture and protect skin from drying out.

PEG-15 GLYCERYL ISOSTEARATE: Cleansing agent that provides good spreading properties and stability to creams and lotions.

PEG-20 SORBITAN COCOATE: Coconut-based cleanser.

PEG-25 GLYCERYL ISOSTEARATE: Stabilizes cleanser formulations.

PEG-40 HYDROGENATED CASTOR OIL: Enhances texture by helping to combine oil-based ingredients in water-based skincare formulations.

PENTYLENE GLYCOL: Anti-microbial agent that helps preserve skincare formulations and has moisture-binding properties.

PERSEA GRATISSIMA (Avocado) OIL (see also HORUS K COMPLEX): Antioxidant with high concentrations of phytosterols (a type of plant-based nutrient) and fatty acids that replenish skin and defend against the look of environmental damage.

PISUM SATIVUM (Pea) SEED EXTRACT: Helps protect dermal proteins and fortify your skin against the look of visible aging.

POLYSORBATE 60 & 80 (the numbers describe the physical state of polysorbate—ranges from semi-solid to liquid.): Texture enhancers that help combine oil-based ingredients in water-based skincare formulas. Help dissolve dirt.

POLYGLYCERYL-10 STEARATE: Stabilizes and enhances texture of foaming cleanser formula.

POLYMETHYL METHACRYLATE: Gives a soft feel to the product.

PORTULACA OLERACEA EXTRACT: Delivers antioxidants and fatty acids to the skin to help promote a youthful appearance.

POTASSIUM HYDROXIDE: Keeps skincare formulas balanced by attracting water to adjust pH.

PPG-6-DECYLTETRADECETH-30: Enhances texture of formula by allowing delivery of oil- and water-based ingredients together.

PROPANEDIOL: Gentle, non-greasy moisturizer that gives skin a soft feel while helping to preserve and enhance the texture of skincare formulas.

PRUNUS ARMENIACA (Apricot) KERNEL OIL (see also HORUS K COMPLEX): Non-greasy, smoothing moisturizer derived from apricot seeds.

PRUNUS LANNESIANA FLOWER EXTRACT: Extract from sakura cherry blossom that soothes and brightens skin.

PULLULAN: Natural sugar that forms a light film on the skin, which provides an immediate skin-tightening effect for a smooth appearance.

PYRUS MALUS (Apple) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Skin moisturizer and a key component of the Olivol Botanical Blend.

Q–R
ROSA CANINA FRUIT OIL (see also HORUS K COMPLEX): Oil from rosehip that hydrates as it delivers antioxidants and fatty acids to the skin for a healthy look.

ROSA MULTIFLORA FRUIT EXTRACT: Antioxidant extract from Eijitsu rose that balances and brightens the complexion. Tightens the appearance of pores.

ROYAL JELLY EXTRACT: Rich in nutrients and amino acids that minimize the look of wrinkles and promote a rejuvenated appearance.

S–T
SAPINDUS TRIFOLIATUS (Soapberry) FRUIT EXTRACT: Helps create a thick, soap-like foam in gentle cleansing formulations.

SCUTELLARIA BAICALENSIS ROOT EXTRACT: Herb with antioxidant and brightening properties. Also acts as botanical preservative.

SILICA: Texture enhancer that also absorbs oil.

SODIUM CITRATE: Used to control the pH level of skincare formulations.

SODIUM HYALURONATE: A salt naturally found in skin’s hyaluronic acid that holds water to promote a hydrated appearance.

SODIUM HYDROXIDE: Used to help balance the pH of skincare formulas.

SODIUM LACTATE: Salt from lactic acid that acts as a natural preservative and exfoliant.

SODIUM PCA: Water-attracting agent that helps bind moisture in the outer layers of the skin.

SOUTHERNWOOD EXTRACT (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Southernwood extract is rich in natural sugars that help stimulate lipid synthesis and storage, increasing density to promote an appearance of “lipofilling” or plumping of the skin.

SQUALANE: This plant-based sugar effectively moisturizes the skin, giving it a visibly soft, supple look.

STEARIC ACID: Saturated fatty acids that are used as a moisturizing and cleansing agent.

TETRASODIUM EDTA: Stabilizes and helps preserve skincare formulas.

TOCOPHEROL: Naturally occurring compound related to vitamin E. Provides antioxidant activity and conditions the skin.

TOCOPHERYL ACETATE: A type of organic compound (ester) from tocopherol (combined with acetic acid). Provides antioxidant activity and conditions the skin, without leaving an oily feeling.

TRIBEHENIN PEG-20 ESTERS: Softens the skin and keeps ingredients in formula from separating.

TRIETHYLHEXANOIN: Provides non-greasy hydration for the skin.

THYMUS (Thyme) FLOWER/LEAF EXTRACT: Contains powerful antioxidant properties.

U–V
UBIQUINONE: Fat-soluble substance naturally found in the body known for antioxidant benefits. Energizes the skin for a noticeably younger-looking complexion.

UV FILTER BLEND: Comprised of four UV filters that offer broad-spectrum protection against the sun’s damaging ultraviolet (UVA and UVB) rays.

  • Avobenzone—protects primarily against UVA rays but offers some protection against UVB, as well
  • Octocrylene—a moisturizing sunscreen that absorbs UVB light and also helps stabilize Avobenzone, which can degrade in light over time
  • Homosalate—absorbs UVB rays
  • Octinoxate—an effective UVB absorber

Celavive Protective Day Lotion and Day Cream both offer SPF 30. Sun protection factor (SPF) is based on how long it takes to sunburn skin that’s been treated with sunscreen compared to no sunscreen.

VITIS VINIFERA (Grape) LEAF EXTRACT: Potent antioxidant that helps diminish visible signs of environmental damage to your skin.

VITIS VINIFERA (Grape) VINE EXTRACT: Liquid from grape and bud vines that contains resveratrol and other antioxidants. Helps smooth the appearance of wrinkles.

W–X
XANTHAN GUM: Natural thickening ingredient.

XYLITOL: Sugar alcohol used as a skin conditioner to promote balanced moisture levels and improve barrier function for healthy-looking skin.

Y–Z
ZANTHOXYLUM PIPERITUM FRUIT EXTRACT: Energizing antioxidant from Japanese pepper that also acts as a botanical preservative.

It’s easy to lose focus in today’s fast-paced world full of packed schedules and constant notifications. But it is possible to take control of your cognition and reclaim your concentration. Optimize your mental performance while supporting cognitive health with USANA CopaPrime+.*

CopaPrime+ is a daily supplement formulated with a powerful blend of nootropics—ingredients that help optimize mental performance—to help support learning and concentration. Clinical studies show measurable results, including:

  • Supporting cognitive agility, with users experiencing over 12% faster reaction times in clinical testing.*
  • Helping optimize mental efficiency, allowing users to complete cognitive tasks 13.7% faster than controls.*
  • Maintaining mental accuracy during demanding tasks, with users showing 16% greater precision than the placebo group.*

Whether you’re focused on family responsibilities, studying at school, or building a successful career, CopaPrime+ can help your brain keep up with the speed of life.*

Nurture Your Neurons for a Healthy Brain


Your brain relies on neurons and neurotransmitters to send messages that control movement, memory, and mood. Age, stress, and lifestyle can weaken these pathways, so keeping neurons healthy with good habits and targeted support like USANA CopaPrime+ helps maintain peak mental performance.*


Your brain and nervous system work like a postal office. In the blink of an eye (or less), messages are received, processed, and then passed along. These messages control conscious and unconscious movements, learning and retention, mood and emotions, memory, senses, and more.

Messages travel via specialized cells called neurons. The chemicals made by neurons to carry the messages are called neurotransmitters. These chemicals travel along a nerve fiber called an axon to be passed to the next neuron at a junction called a synapse. The synapses are on the ends of branches called dendrites, which extend from the cell body to receive messages.



Many factors support the strength and structure of your neurons, which are directly related to your cognitive function. Healthy aging, supporting the body’s response to mild, occasional stress, eating a balanced diet, and exercising can help maintain your brain’s communication pathways.

Your neurons are some of the longest-living cells in your body. So, keeping them healthy is key to maintaining normal brain function. Targeted supplementation, such as USANA CopaPrime+, can be added to healthy lifestyle habits to help promote peak mental performance.*

CopaPrime+ Benefits Backed Up by Clinical Studies


CopaPrime+ supports memory and concentration, key areas for learning and decision-making. In clinical studies, participants taking the formula demonstrated 12.33% faster reaction time, 16% higher accuracy, and 13.7% faster processing speed compared to placebo, helping support focus, working memory, and attention control.*


CopaPrime+ supports key areas of your brain: memory and concentration. Two independent clinical studies show how the CopaPrime+ formula helps to increase efficiency in these key areas.*

  • Best T, Clarke C, Nuzum N, Teo WP. Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study. Nutritional Neuroscience. 2019;24(11):873-884.
  • Best T, Miller J, Teo WP. Neurocognitive effects a combined polyphenolic-rich herbal extract in healthy middle-aged adults – a randomised, double-blind, placebo-controlled study. Nutritional Neuroscience. 2024;27(11):1293-1305.

Memory

Short-term memory, also known as “working memory,” is crucial for reasoning, decision-making, behavior, learning, and comprehension. These are the skills used for any mental task, whether tapping into creativity for a writing project, evaluating a math problem, or analyzing data. As new information comes in, it combines with information already in your working memory.

Working memory was evaluated using the N‑back task. Participants watched a sequence of letters from A-J and tried to recognize when a letter matched the same as the one presented “N” times ago.

  • In the 2-back test, participants taking the formula demonstrated a 12.33% faster reaction time compared to placebo.*
  • In the more demanding 3-back test, participants showed 16% greater accuracy compared to placebo.*

Concentration

The ingredients in CopaPrime+ have been shown to help support selective attention, which is the ability to direct awareness and ignore distractions, and speed of attention—the time it takes to settle into focused, deep-thinking work.*

Concentration was tested through the Stroop task, which is used to measure cognitive interference by asking participants to name the ink color of words, not read the words themselves (e.g., the word RED written in the ink color BLUE).

  • In this test, participants demonstrated a 13.7% faster processing time from baseline relative to controls, helping support efficient attention and cognitive performance.*

Results from two randomized, placebo-controlled clinical studies:


CopaPrime+ Ingredients Optimizes Connections


CopaPrime+ combines InCelligence Cognitive-Support Complex and American ginseng to helps support learning, memory, focus, and mood. These nootropics—substances that help maintain peak mental performance—support neurotransmitters, BDNF levels, and stress resilience, helping promote brain health and peak mental performance.*


Take a closer look at the nootropics in USANA CopaPrime+.

American Ginseng

Along with antioxidant properties, American ginseng (Panax quinquefolius) supports learning, attention, memory, clarity, mood, and tranquility.*

Ginseng contains special compounds called ginsenosides that help promote brain health. These compounds support a system in your body that makes acetylcholine (ACh)—a chemical messenger that helps your nerves communicate. ACh is important because it helps your brain stay flexible and form new connections, which is key for learning and memory.*

Ginseng has been used for centuries in Chinese culture to help manage occasional stress, optimize mental clarity, and promote soothing Yin energy (instead of invigorating Yang energy). By combining traditional wisdom with scientific validation, American ginseng offers a natural way to optimize mental clarity, support brain health, and promote a positive mood, making it a valuable ingredient for supporting overall cognitive performance.*

InCelligence Cognitive-Support Complex

CopaPrime+ includes InCelligence Cognitive-Support Complex, a combination of ingredients that support cognitive health—including contributing to BDNF.*

Brain-derived neurotrophic factor (BDNF) is one of four types of neurotrophins—proteins that control the survival, development, function, and maintenance of neurons. Maintaining adequate levels of BDNF in the brain is critical for normal cognitive and nervous system function. Learning, mood, focus, and memory all rely on this important protein.*

The ingredients in the InCelligence Cognitive-Support Complex support a new approach to brain health by supporting cognitive health and BDNF levels.*

Bacopa

Bacopa monnieri (also known as brahmi or water hyssop) is an herb that’s been used for thousands of years in Ayurveda—the holistic approach to health practiced in Indian culture. There are even reports that bacopa may have been used in India between 1500 and 1000 B.C. to help scholars memorize lengthy hymns. So, it’s also long been used to support intellect.*

The naturally-derived extract used in CopaPrime+ has a high amount of Serotonin Active Bacopa Glycosides. This simply means it targets cell receptors that play a major role in cognition, while also supporting a sense of well-being.*

Bacopa has been shown to support the production of ACh for normal cell signaling, which is key for learning and memory. It’s also an antioxidant and can act as an adaptogen—a substance that helps your body handle the effects of mild, occasional stress.*

Whole Coffee-Fruit Extract

The health benefits of coffee go beyond the beans you brew. The cherry fruit that those beans come from also offers valuable nutrients when harvested and processed properly. The naturally-derived coffee fruit (Coffea arabica) in CopaPrime+ is extracted using a proprietary process that preserves high levels of chlorogenic acid (a source of polyphenols), but it has low amounts of caffeine.*

The unique phytonutrient profile of this coffee extract makes it more active in the body. This potency has been shown to support healthy BDNF levels in clinical studies. The extract also offers antioxidant activity for added optimization for your brain cells.*

Stay Sharp With CopaPrime+


Cognitive functions that can change during healthy aging are speed of information processing, memory, spatial ability (related to remembering and visualizing images), and reasoning. CopaPrime+ can help you maintain a healthy brain and nervous system, which are key to supporting mental sharpness and cognitive function.*

Key Ingredients

  • American ginseng
  • InCelligence Cognitive-Support Complex (bacopa and coffee extract)

Usage

  • Adults, take two (2) tablets daily, preferably with food.

Ideal For

  • All healthy adults over age 18
  • College students
  • Career-focused professionals
  • Mature individuals interested in maintaining mental performance and memory

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions About CopaPrime+

CopaPrime+ was not designed for use by children. The labeled dosage on CopaPrime+ is appropriate for adults over 18.

A. The ingredients in CopaPrime+ have been used in numerous clinical studies and tolerated well. Some study participants who consumed doses higher than those provided in CopaPrime+ experienced mild headache or digestive upset, which went away naturally. If you experience a side effect after taking CopaPrime+, try taking it with food and reducing the dose to one tablet a day, then gradually returning to the full dose, as tolerated.

A. There are trace amounts of caffeine from the natural coffee-fruit extract in CopaPrime+.

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USANA Nutritional Supplements

USANA Celavive Skincare Products

USANA Personal Care Products

USANA Active Nutrition Products

Design Your Best Health with USANA Products

Taking charge of your health begins with the smart choices you make every day. USANA can help you become your best self with products that support optimal health, inside and out: Science-based supplements help support daily wellness, so you can keep up with your busy life. Balanced diet and energy products can fuel your fitness or weight-management goals. And advanced skincare and personal-care products help reveal your natural beauty.

Trust your health to USANA’s high-quality products and you can start living your healthiest, most vibrant life today.*

Follow these four simple steps to create a health regimen that supports your health goals:

  1. Start with a strong foundation by choosing the Essential Nutrition supplement that works best for you.
  2. Add Optimizers—the USANA supplements that will target your unique health needs.
  3. Select Celavive Skincare and Personal Care products to help you look as great as you feel.
  4. Round out your routine with Food and Energy products to help fuel your day.

Search USANA Products by Category

USANA Nutritional Supplements

A complete range of vitamins and supplements, from multivitamins for the whole family to targeted products designed to address your individual health needs.

Essential Nutrition

CellSentials™—Comprehensive daily multivitamin and mineral supplement that also supplies antioxidants and other important nutrients for your overall health and wellness. Features the InCelligence Complex to promote optimal cellular function.*

HealthPak™—Convenience pack with advanced nutrition for modern lifestyles. Includes morning and evening doses of the CellSentials, plus MagneCal D (a calcium, magnesium, and vitamin D supplement) and the CellSentials Booster, which is made exclusively with USANA InCelligence Technology™.*

Prenatal CellSentials™—Vitamin and mineral supplement that includes iron for women who are pregnant, breastfeeding, or who may become pregnant.*

Body Rox™—Daily vitamin, mineral, and antioxidant supplement for teenagers.*

Usanimals™—Chewable vitamin, mineral, and antioxidant supplement for children.*

Optimizers

BiOmega™—Highly purified fish-oil supplement that provides concentrated omega-3 fatty acids plus vitamin D to support many aspects of health, including cardiovascular and brain function.*

Booster C 600™—Lemon-berry flavored powder that supplies ingredients shown to support immune health when you need an occasional boost.*

CopaPrime+™—Supports peak mental performance and protects long-term brain health with American ginseng plus the InCelligence Cognitive-Support Complex.

CoQuinone® 30 | CoQuinone 100—Coenzyme Q10 supplement with alpha-lipoic acid to support a strong heart.*

Digestive Enzyme—Supplies enzymes to help you digest your meals more efficiently.*

EstroPro™—Phytoestrogen supplement that helps relieve many common symptoms of menopause.*

Glow—Add Glow to Your Celavive Skin Routine.*

Hepasil DTX™—Liver-support formula made with choline and the InCelligence Detox-Support Complex to support your body’s natural detoxification processes.*

Iron—Optimize your blood health and support healthy energy with help from USANA Iron.*

MagneCal D™—Contains magnesium, calcium, and vitamin D for skeletal support.*

Palmetto Plus™—Combination of saw palmetto, lycopene, and soy isoflavones to support prostate health.*

Probiotic—Probiotic supplement for digestive and immune health.*

Procosa®—Supports joint health with key nutrients, including vegetarian glucosamine, vitamin C, and curcumin.*

Proflavanol® C100 | Proflavanol C200—Powerful bioflavonoid supplement featuring USANA’s exclusive vitamin C blend (Poly C®) and grape-seed extract to support healthy circulation and more.*

Proglucamune™—Contains the InCelligence Beta-Glucan Complex and zinc to support healthy immune function, even during times of stress.*

Pure Rest™—Melatonin supplement to support natural sleep and wake cycles.*

Rest Complete—Wind Down for Sleep with USANA Rest Complete.

Stress Relief—Mood-support supplement features three adaptogens to help support the ways your body handles occasional stress.*

Visionex® | Visionex DS—Vision-support formula designed to help maintain long-term eye health, featuring lutein and zeaxanthin.*

Vitamin D—Helps prevent vitamin D deficiency and supports many aspects of health.*

Vitamin K2—Long-acting vitamin K2 that helps keep your bones and cardiovascular function strong.*

Wondering where to start?

Science shows that the majority of people would benefit the most from adding these products to their daily routine.

CellSentials™
Most dieticians recommend a broad-spectrum multivitamin, mineral, and antioxidant supplement to fill any nutritional gaps.

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BiOmega
An estimated 90 percent of people don’t consume enough omega-3 fatty acids to get the full range of their health benefits.*

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Vitamin D
A supplement is the easiest way to avoid the world’s most common nutrient deficiency.*

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USANA Celavive Skincare Products

Renew your natural radiance with USANA Celavive® Skincare products that can help support a healthy complexion and fight the visible signs of aging. Learn more about Celavive Skincare.

Postbiotic Skincare—Nourish your skin’s natural moisture barrier for radiant, healthy-looking skin with this microbiome-friendly series of products. Featuring Celavive Postbiotic Calming Cleanser, Rescue Serum, Soothing Moisturizer, and Barrier Balm.

Conditioning Makeup Remover and Bi-Phase Makeup Remover —Lifts stubborn makeup from the skin while conditioning with sugar-based moisturizers.

Creamy Foam Cleanser—Gently cleanses as it balances moisture.

Exfoliating Scrub+Mask—Dual-action formula polishes and purifies skin.

Contouring Face and Neck Cream—Delivers moisture and active ingredients to the skin.

Hydrating + Lifting Sheet Mask—Noticeably tightens and smooths the look of your skin in only 20 minutes.

Perfecting Toner—Completes cleansing process, hydrates, and prepares skin for treatment products.

Protective Day Cream and Lotion—Hydrates and shields skin from the sun with a broad-spectrum SPF 30 sunscreen.

Radiant Facial Oil—A lightweight moisturizing facial oil.

Resurfacing Serum—Advanced formula targets visible dark spots and hyperpigmentation for smoother, brighter, youthful-looking skin.

Triple-Action Eye Cream—Reduces the appearance of wrinkles and fine lines around the eyes.

Vitalizing Serum—Visibly firms and brightens skin while reducing the appearance of wrinkles, fine lines, and pores.

USANA Personal Care Products

USANA® Oral Care: Whitening Toothpaste and Oral Probiotic—Works together to keep you smiling bright with whiter teeth and a clean, fresh mouth.

USANA Foods

Activate your goals with USANA Active Nutrition. Discover how this nutritional program optimizes your digestion, weight-management efforts, hydration, and overall wellness

Circulate+—Support nitric oxide production, healthy blood flow, circulatory health, and overall wellbeing.

Core Aminos—Formulated with all nine essential amino acids and combined with beta-hydroxy beta-methylbutyrate.

Marine Collagen Peptides—A ready-to-drink collagen beverage for sharing with friends or any on-the-go lifestyle.

Metabolism+—See how a metabolism supplement can support your wellness goals, and make maintaining a healthy weight is more manageable.*

Fibergy Active—Find out how fiber helps digestion and can optimize your gut health.*

Nutrimeal™—Low-glycemic meal replacement shake.

Nutrimeal Active—Reach your fitness and nutrition goals with the help of a tasty, protein-packed meal replacement shake.

Rev3 Energy® Drink—Refreshing, low-glycemic energy drink.

Rev3 Energy® Surge Pack—Convenient, ready-to-mix powder.

Revolve Fizzy Energy Drink—Essential Nutrients for Physical Performance

Electrolyte Replacement Drink Mix—Mix up a tasty way to optimize your energy and hydration.*

Detox Tea Drink Mix—A refreshing tea that helps support your digestive health.*

Peanut Butter Snack Bar—A delicious, health-friendly option to power you between meals.

Collagen Protein Bars—A high-fiber and high-protein snack that will help keep you energized throughout the day.

Whey Protein Isolate—Support muscle growth, recovery, and overall nutrition with premium, grass-fed, USANA Whey Protein Isolate.

Learn More About USANA Products

USANA Product Usage During Pregnancy and Lactation

USANA Product Allergen Chart

Which USANA Products Can Be Used By Children?

USANA EstroPro

Ease some of the effects of menopause and get back to feeling like yourself with a unique blend of phytoestrogens.*

Find Relief from Common Menopause Symptoms with USANA EstroPro*

To say the symptoms of menopause can interrupt your life is putting it mildly. Suddenly, you have your very own personal heat wave that flares up at the most inconvenient times. A full eight hours of sleep is a thing of the past. And your mood and mind can seem like they’re all over the place. You simply may not feel like yourself anymore. But, you can take control of your menopause symptoms and find relief with USANA EstroPro. This phytoestrogen supplement provides a uniquely potent blend of four clinically studied botanical extracts that can help you get back to feeling like yourself again.*

EstroPro makes it easy to add the benefits of naturally-derived, estrogen-like compounds—isoflavones from soy and red clover, plus licorice and flaxseed—to your daily life. Consistently taking two tablets a day is the key to maximizing the benefits:

  • Provides relief for many common symptoms of menopause (hot flashes and night sweats, difficulty sleeping and fatigue, mood swings, appearance of aging)*
  • Supports bone and heart health after menopause*
  • Provides gentle estrogenic effects to support balanced hormone function*

Changes associated with the transition to menopause (perimenopause) can begin as early as your thirties, but are more common in your forties. But the end of fertility that comes with menopause doesn’t mean the end of a vibrant, active lifestyle. You have a lot going on. And these years are yours to enjoy. USANA EstroPro can help you find freedom from common menopause complaints, so nothing will get in the way of feeling your best every day.*

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Menopause: The Stages, Signs, and Side Effects

A woman’s life comes with many changes—from her first menstruation cycle through the end of her reproductive cycle. Each brings its own joys and challenges. Menopause causes changes related to the natural shift to lower levels of estrogen and progesterone in the body. These shifts are triggered by reduced function of the ovaries that happens in middle age. Menopause also marks the permanent end of fertility.

You’ll encounter the term “menopause” throughout this page to describe the gradual transition that occurs in three stages:

  1. Perimenopause—or pre-menopause—is the time leading up to menopause. There is a large variation of when this can begin. Most women begin to experience the symptoms between the ages of 40 and 58. The average age is 51. And, it can last anywhere from seven to 14 years.
  2. You’ve officially made it to menopause 12 months after your last menstrual period.
  3. Post-menopause is the aptly named time after menopause. You may continue to experience some of the symptoms of perimenopause.

Every woman’s menopause experience is different. You may not experience any side effects. But more than 85 percent of women are estimated to experience at least some symptoms related to declines in estrogen. The following are some signs and symptoms of menopause:

  • Irregular periods (there’s still a likelihood you could become pregnant, so continue any birth control until you haven’t had a period for at least 12 months)
  • Mood swings
  • Weight gain
  • Hot flashes/flushes and night sweats
  • Difficulty sleeping and increased fatigue (often related to night sweats)
  • Headaches
  • Vaginal dryness
  • Changes in sex drive
  • Increased wrinkling and dryness of the skin

Fortunately, there are a number of actions you can take to help ease the transition, including adding EstroPro to your daily routine. It was designed to help provide relief from some of the most troublesome side effects of normal menopause: hot flashes, night sweats, changes in skin and hair, mood swings, and occasional sleeplessness.*

Make sure to meet with your doctor to discuss your experiences, especially if your symptoms start to disrupt your life or become painful.

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Lifestyle Strategies for Managing Menopause Symptoms

If the side effects of menopause have you feeling less than your best, there are a few approaches you can try to find relief and get back to living your life on your own terms.

USANA® EstroPro™ is a great place to start. The gentle effects of the phytoestrogen supplement can help balance hormones and ease some of the most commonly reported menopause symptoms. It was created by USANA scientists using effective, well-researched ingredients.*

Two tablets of EstroPro per day provide 48 milligrams (mg) of soy and red clover isoflavones, 105 mg of flaxseed, and 60 mg of licorice, daily. These naturally-derived ingredients are gentle and effective because they function as mild phytoestrogens, which are estrogen-like compounds found in plants. With regular use, EstroPro can help improve your quality of life during the transition to menopause and the years following.*

The North American Menopause Society also offers a number of suggestions for dealing with the change of life. Their recommendations for hot flashes and difficulty sleeping include the following:

  • Exercise regularly and do your workouts early in the day (exercising too close to bedtime could make it harder to sleep)
  • Consume a healthy diet that includes nutritious whole foods—consider adding more soy to your diet to get the benefits of their phytoestrogen properties
  • Limit caffeine, alcohol, spicy foods, and hot beverages
  • Sleep in light clothing and layer your bedding so you can add or remove as needed
  • Keep your bedroom dark, peaceful, and cool—use a fan along with a cooling pillow or mattress
  • Manage your stress and practice deep breathing when a hot flash strikes or you can’t sleep

Maintaining a healthy weight before menopause could help lessen the severity of the side effects. This is because women who are overweight or obese can be more likely to experience hot flashes, especially early in the transition.

The 5-Day RESET, and Nutrimeal can help make it easier to manage your weight. A number of other USANA products can also help support many aspects of your health during menopause. You’ll find them listed throughout the rest of this page. *

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Keep Your Cool with EstroPro—Gentle Relief for Menopause Hot Flashes

woman lying down on yoga mat meditating surrounded by wellness equipment and EstroPro

You’re going about your day when, suddenly, the top half of your body feels like you’re locked in an unbearably hot sauna. You break out into a sweat and your face turns red. You start removing layers of clothing and reaching for ice water or a fan—anything to help you cool down. It’s difficult to think about anything else until the heat wave subsides.

If this matches your experience, you’re not alone. Hot flashes (also called “flushes”) are the most common menopause-related discomfort.

Hot flashes involve an almost instantaneous flare of heat that can last anywhere from a few seconds up to five minutes. They can happen infrequently or many times a day. Sweating and flushed skin often come along for the ride. And, you may also experience a racing heartbeat. Finally, once the heat has subsided, you could feel like you’ve been blasted by a cold chill.

The scientific community refers to hot flashes as “vasomotor symptoms,” because they involve the constriction and dilation of blood vessels. Declining estrogen and changes in the part of the brain that regulates body temperature are thought to cause the vasomotor actions that trigger hot flashes.

Hot flashes are typically the worst in the first couple years of menopause. However, ethnicity, as well as lifestyle factors—like stress levels or smoking—can contribute to variations in how long you may experience hot flashes. And the symptoms can vary greatly in intensity and duration.

Fortunately, you don’t just have to put up with hot flashes. You can take back control over your day with EstroPro—a supplement that will help you keep your cool.*

There is good evidence that the ingredients in EstroPro can help relieve the vasomotor symptoms associated with menopause. The unique blend of soy, red clover, licorice, and flaxseed is designed to help reduce the frequency or intensity of hot flashes.*

Each ingredient in EstroPro has been studied in menopausal women—with the majority of research centering on soy isoflavones. When the ingredients are combined, you get broad support to help ease hot flashes:

  • Consumption of supplemental isoflavones from soy (Glycine max) has shown to result in fewer hot flashes. Effects can begin to be felt as early as six to 12 weeks after beginning supplementation. And long-term use is recommended. One meta-analysis found that hot flashes were less severe when taken for about a year.*
  • Red clover (Trifolium pretense) isoflavone supplementation has also been shown to be more effective than placebo in cutting down the number of hot flashes and reducing “overall menopausal intensity.”*
  • Small studies have indicated benefits for hot flashes with licorice (Glycrrhiza glabra) supplementation, but more research is needed.*
  • Research reviews have found that flaxseed (Linum usitatissimum) appears to offer some mild beneficial effects for hot flashes.*

Together, these ingredients provide an effective way to tame the flame of your hot flashes, so you can feel cool, calm, and collected throughout your day.*

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Manage Menopause Mood Swings and Mental Fog Caused by Fatigue with EstroPro

The disruptions of hot flashes don’t just happen during the day. Hot flashes while you’re trying to sleep cause night sweats. And waking up in bed, drenched in perspiration and feeling like you’re on fire can significantly impair your sleep. This could leave you sluggish—mentally and physically—and irritable the next day.

Over time, a lack of sleep could start a downward spiral—for your health, mood, and energy levels. Helping to relieve hot flashes and night sweats is one way EstroPro helps you manage your mood and fight fatigue during menopause.*

But the benefits of EstroPro extend beyond its effect on hot flashes. It can also provide support for maintaining normal sleep and a stable mood in other ways.*

The normal decline of estrogen during menopause does more than cause changes in how your brain regulates the heating and cooling of your body. The same changes can also impact your mood. That’s due to a decrease in the release of certain neurotransmitters (chemical messengers in the brain). This includes a drop in norepinephrine, which underlies your fight-or-flight stress response, and serotonin, which contributes to feelings of well-being and happiness.

Similarly, menopause-related changes in estrogen levels can also impact your normal sleep hormones—having an impact on your circadian rhythms. There are also effects on your endocrine hormones, which influence the functions of many different glands in your body. These include your ovaries and pituitary gland, which affect your reproductive system, among others.

The fluctuations in your various hormone systems can all add up to not feeling yourself due to poor sleep or alterations in mood. These changes are normal for women during menopause—even more so for women who experienced changes in mood due to premenstrual syndrome (PMS) in their younger years.

The fact that these symptoms are normal doesn’t make them any easier to experience every day. The ingredients in EstroPro have been shown to help lessen the impacts of menopause on your mood and sleep by offering similar activity to your natural estrogen.*

  • Soy and red clover isoflavone consumption have been associated with improved sleep and a stable mood during menopause. *
  • The active compounds in licorice have demonstrated unique function on the serotonin system, suggesting potential benefits on mood during menopause, as well.*

Another complaint of some menopausal women is experiencing brain fog—a slowdown of cognitive function. Research has confirmed that mental performance and memory can be different during menopause. So, if you’ve noticed a difference, it’s not all in your head (figuratively speaking).

Lack of sleep could be one explanation. So, use EstroPro to cut down on hot flashes and night sweats to improve your chances of getting healthy sleep. This will help you feel less tired and support your mental clarity.*

Beyond taking EstroPro to support a balanced mood, a clear head, and a good night’s sleep, there are other USANA products to support overall health. Adding a broad-spectrum supplement like the HealthPak, along with BiOmega, to a balanced diet can help you get the right foundation of nutrients to maintain your overall health and energy levels. CopaPrime+™ can help maintain memory and cognitive function. And, Pure Rest can help support your body’s sleep and wake cycle to help you get to sleep.*

Note: If the changes in your mood are severely impacting your quality of life, please talk to your healthcare provider for more solutions.

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Support Your Skin’s Ageless Beauty During Menopause

beautiful mature woman

From laugh lines to the visible effects of adventures out in the sun—a life well-lived will show up on your skin. And you can help maintain your naturally ageless beauty by supporting the health of your skin with the ingredients in EstroPro.*

There are estrogen receptors in the layers of your skin (this includes on the scalp, where they play a role in hair growth). So, as your estrogen levels gradually decline during and after menopause, the effects can show up on your complexion more quickly. Skin becomes thinner and more fragile, wrinkles and sagging may appear due to reduced collagen, and skin becomes drier.

Consuming isoflavones from soy and red clover has shown promise for maintaining the appearance of skin in middle-aged women. A 12-week study in postmenopausal women who consumed 40 mg/day of soy isoflavones in a test food showed improvements in fine wrinkles and skin elasticity.*

Similar positive results in skin texture, elasticity, and appearance have also been seen in other research. And participants in a study who received red clover extract not only reported subjective benefits in skin condition but hair condition, too.*

There’s a lot more you can do to help your skin age beautifully. In addition to a healthy diet and lifestyle habits, applying quality ingredients on your skin can also deliver visible results. Celavive Skincare uses exclusive technologies that help rejuvenate skin’s natural processes for preserving hydration and firmness for a more youthful appearance.

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Pump Up Support for Your Cardiovascular Health During Menopause with EstroPro

EstroPro surrounded by fitness gear

You have a lot to love about your life by the time you’ve hit middle age. And caring for your cardiovascular health after menopause is especially important, so you can keep enjoying life to its fullest.*

Estrogen helps protect cardiovascular health by supporting healthy endothelial function. The endothelium lines the walls of your blood vessels, where the endothelial cells control relaxation and contraction to regulate blood flow. The normal changes in endothelial function associated with menopause could at least be partially to blame for vasomotor symptoms—hot flashes.*

As your estrogen naturally declines during menopause, research has shown you can use phytoestrogens like soy isoflavones to help maintain normal endothelial function. The phenolic compounds (types of antioxidants) in flax may also help provide defense against free radical damage to endothelial cells. This means EstroPro can help support your vascular health during menopause.*

Soy, red clover, and flaxseed have also been shown to help support healthy cholesterol levels, as long as they’re already in the normal range. Red clover may provide additional support for maintaining normal triglyceride levels, too.*

You can learn more about a heart-healthy lifestyle in this article on Navigating the Cardiovascular System. For additional nutritional support, you can also help protect a strong heart with CoQuinone and help maintain healthy circulation with Proflavanol C.*

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Phytoestrogens in EstroPro Help Strengthen Support for Bone Health

woman doing yoga

The increased confidence that comes with age isn’t your only source of inner strength. A strong skeleton is also necessary to support your body through whatever may come its way.

Estrogen plays a role in your bone health. It helps keep bone remodeling balanced—the process by which older bone tissue is removed from the skeleton and new bone is created. Maintaining a balance is important so you don’t lose more bone than your body makes. But when estrogen levels naturally drop after menopause, the result can be an imbalance between the types of cells needed to create bone (osteoblasts) and remove bone (osteoclasts).

You can learn more about this process in this article on Understanding Bone Anatomy.

The rate of bone remodeling tends to increase after menopause. And it’s common for the pace of bone formation to lag behind the rate of bone resorption (the term for what happens when your body absorbs bone). This is why women lose bone more rapidly during the first four to eight years after menopause, especially in the hip, wrist, and spine.

The ingredients in EstroPro may help you maintain healthy bone mineral density during and after menopause to protect strong bones.*

Phytoestrogens can provide somewhat similar structural activity to your natural estrogen to help maintain bones. Research has shown supplementation with isoflavones can help maintain bone mineral density, as measured in the hip joint and lower spine. Most studies use soy, but red clover has also shown some benefit.*

Isoflavones have demonstrated support for maintaining bone-calcium content, promoting bone formation, and reducing the rates of resorption. And supplementation over the long-term is important—one study showed benefits over three years.*

Research has also suggested that licorice may help support healthy bone remodeling when combined with quercetin. This makes the licorice in EstroPro a great complement for the higher levels of quercetin you get with the HealthPak. You can further support strong bones by also adding Vitamin K2 and/or Vitamin D to your daily routine. (Or, if you opt to take the CellSentials instead of HealthPak, you’ll also want to add MagneCal D).

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EstroPro Delivers Unique Blend of Naturally Derived Phytoestrogens to Support Hormone Balance

EstroPro is able to help support so many aspects of health during menopause because it provides phytoestrogens—ingredients that have structural similarities to your natural estrogen. When your natural estrogen declines, the phytonutrients can attach to open estrogen receptor sites on various cells to support similar functions.*

EstroPro contains two major classes of phytoestrogens: isoflavones and lignans (which are structurally different plant compounds).*

  • Soybeans and red clover are both isoflavones. Licorice is a flavanone (which is structurally similar to an isoflavone) that also offers some estrogenic effects.*
  • Flaxseed is the richest food source of lignans.

Isoflavones are the most well-researched class of phytoestrogens. There are a number of different types of isoflavone molecules that can come from various sources. They include genistein,  daidzein, formononetin, and biochanin A. The names aren’t really important to remember. But you’ll see genistein mentioned most frequently in studies.*

USANA scientists designed EstroPro to supply a diverse formula of naturally-derived botanicals for broad benefits. Soy and red clover have similar chemical profiles. But soy contains more genistein and daidzein. Red clover delivers higher levels of formononetin and biochanin A.

woman in kitchen slicing lemons surrounded by healthy foods and a bottle of EstroPro on counter

The blend of soy and red clover, along with the added licorice extract, will give you a balanced mixture of isoflavones. This mix more closely reflects what you would get if you ate a diet that provided a healthy balance of soybeans and unfermented soy foods.*

The interest in mirroring a diet high in soy stems from the fact that Asian women tend to have an easier time transitioning through menopause. They consume considerably more soy than women in Western cultures. Because Western diets rarely contain much soy, a supplement is a convenient way to deliver their beneficial compounds.*

But not all supplements made with soy isoflavones are the same. The soy isoflavones that come from whole soybean—not soy germ—are more concentrated. And the form of isoflavone also matters. EstroPro is formulated to provide an effective amount of a highly absorbable form of soy isoflavones that come from whole soybeans for more potent activity.*

Soy isoflavones can come in one of two forms: a glycoside or an aglycone. A molecule of soy from food includes a sugar as part of its structure. This is the glycoside (glycol = sugar) form. That sugar has to be removed during digestion before the nutrients can be absorbed.

An aglycone is an isoflavone that already has the sugar removed, so it absorbs faster. USANA EstroPro is formulated to provide an effective amount of aglycones to provide the most active formula possible.

You can also increase your soy consumption by eating foods like miso, edamame, or tempeh.

The lignans from flaxseed also make EstroPro unique.

Lignans are distinctive because they only provide estrogenic activity in the body if your estrogen levels are low. If there is plenty of estrogen already available to your cells, then the flaxseed won’t provide additional estrogenic effects. This makes EstroPro a good choice, regardless of where you are in your menopause journey, because it can adapt to your needs.*

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Key Ingredients

  • Isoflavones
  • Flaxseed Extract
  • Licorice Extract

See complete list of ingredients

Usage

Women 40 and older, take two (2) tablets spaced evenly throughout the day.

Do not take this product if you are pregnant, nursing, taking a prescription drug, or have a gastrointestinal disorder or other medical condition without first consulting your physician.

Ideal For

  • Women over 40

Frequently Asked Questions About EstroPro

USANA® EstroPro™ is a phytoestrogen supplement that helps relieve common symptoms of menopause, including hot flashes, night sweats, mood swings, sleeplessness, and fatigue. It also helps maintain bone and cardiovascular health. EstroPro contains isoflavones from soy and red clover, as well as licorice and flaxseed extracts, for broad support.*

Phytoestrogens can be subtle in their effects and results will vary by individual. A meta-analyses of studies found some effect of soy isoflavone supplementation in as early as six weeks. However, the effects are greater with longer periods of use. Many studies show benefits after three to six months of use. But, a different meta-analysis estimated it can take up to 48 weeks to achieve 80 percent of the maximum beneficial effects of soy isoflavones. An informal, in-house survey found that women noticed a difference after about two months of using EstroPro.*

If you don’t eat much soy in your daily diet, it may take longer to see an effect. You can consider taking an increased dosage of up to four EstroPro tablets a day, for three to four months, to increase levels of active ingredients more quickly. Spread consumption of the tablets throughout the day.

Please consult your healthcare provider or a pharmacist before adding EstroPro (or any other supplement) to your routine to determine if it’s the right approach for you.

The majority of research in humans has shown that soy is not only safe, but it is actually beneficial for health. This includes offering support for breast and cardiovascular health. Every individual is unique, and we encourage you to discuss any concerns with your healthcare provider.*

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.