Proglucamune™: What You Need to Know
Mushrooms have been used for thousands of years to support well-being in traditional Asian cultures. Proglucamune combines a unique blend of organic, antioxidant-rich shiitake and reishi mushroom powders with a proven strain of baker’s yeast to create the USANA InCelligence Technology™ Beta-Glucan Complex.
Who can take Proglucamune?
Proglucamune is only intended to be taken by healthy adults, 18 years and older. Proglucamune is not recommended for children unless being taken under the supervision of a medical professional.
Any individual with an autoimmune disorder should consult their doctor before using Proglucamune. USANA has no clinical data to support either the safety or efficacy of Proglucamune in individuals with autoimmune disorders. Additionally, individuals who are taking medications should also consult their physicians prior to use.
Will Proglucamune help if I am already sick?
Proglucamune helps prime the body to counter the initial presence of foreign pathogens. To do this, the product must be taken continually and already be in the system. It would not be expected to offer any benefit for those who are already sick.
Proglucamune usage should be discussed with a healthcare professional prior to use during pregnancy and lactation. It contains ingredients that lack sufficient safety data for USANA to recommend its general usage during pregnancy.
The bioactive components of mushrooms—known as beta-glucans—bind to receptors on the outside of immune cells and trigger cell-signaling pathways. The result of these cell-signaling pathways is to “wake up” that immune cell and bring it to a heightened state. Once the immune cell is in this heightened state, it can now more effectively help to defend us from the outside world—a mechanism known as “priming”.
Reishi and Shiitake Mushrooms
Reishi and Shiitake mushrooms have long been used in ancient cultures to enhance the immune system, help facilitate calmness, and strengthen qi—our so-called circulating life force that is the basis of Eastern philosophy and medicine. Scientists have now isolated the major “bioactive components” of mushrooms (known as beta-glucans) and modern medicine has confirmed what has been observed for literally thousands of years. USANA wanted to leverage the health-promoting ingredients of these two mushrooms and why they were chosen to be a part of the potent Proglucamune formula.
Mushroom Extract vs Mushroom Powder
There absolutely can be differences between extracts and powdered forms of mushrooms. Most of the health benefits attributed to yeast and mushrooms come from a class of compounds found in their cell walls called beta-glucans. These beta-glucans tend to be large molecules and are tightly bound in the cell wall. Additionally, some types of beta-glucans are insoluble in water. Together, this can make the extraction process inefficient, error prone, and even leaving health-promoting compounds behind. What is important—whether an extract or powder—is the potency and standardization of the health-promoting beta-glucans. USANA has deliberately chosen to utilize yeast and mushroom powders to deliver the most potent, reliable, and efficacious formulation possible.
Why is the mushroom mycelium used, instead of the fruiting body?
There are not major differences in the levels of health-promoting beta-glucans found in the different structures of a mushroom. This especially applies when the fruiting body (mushroom cap) is compared to the mycelium (vegetative growth). USANA has deliberately chosen to utilize mycelium powder to deliver the most potent, reliable, and efficacious formulation possible.
What is the difference between consuming the actual ingredients, as compared to taking Proglucamune?
Two major reasons come to mind. First is potency. Yeast and mushrooms tend to be very bulky in size relative to their weight. It would be very difficult to consume enough yeast and mushrooms, consistently, day-after-day to achieve clinical dosages of beta-glucans shown to have health benefits.
Second, Proglucamune utilizes a proprietary strain of yeast to leverage the health benefits of a specific beta-glucan with proven clinical results. Utilizing the concentrated and standardized ingredients found in Proglucamune help ensure you are achieving clinical dosages of beta-glucans to help keep you at your healthiest.
The beauty of leveraging cell-signaling—the basis of USANA’s InCelligence Technology—is that no two products will work the same. The action of Proglucamune is entirely unique to anything in USANA’s product portfolio. The bioactive components of mushrooms, beta-glucans, bind to receptors on the outside of immune cells and trigger cell-signaling pathways. The result of these cell-signaling pathways is to “wake up” that immune cell and bring it to a heightened state. Once the immune cell is in this heightened state, it can now more effectively help to defend us from the outside world—a mechanism known as “priming”.
What can negatively affect our immune system?
Many things can negatively affect our immune system. For example, our busy lifestyles, lack of sleep, stress, pollution, travel, poor diet, lack of exercise, competitive athletics, and a lack of sunlight can all keep our immune system from running as effectively as possible.
What other products/ingredients support our immune health in addition to Proglucamune?
Many ingredients have been shown to help support a healthy immune system. For example, vitamin D, omega-3 fatty acids, vitamin C, zinc, and Echinacea. Additionally, all cells in our body need essential vitamins and minerals to function optimally. Proglucamune works via a unique mechanism called priming. Once an immune cell is primed it can better support our body’s natural immune response. The other ingredients listed above all work through entirely different mechanisms than Proglucamune. Because of the different mechanisms of these ingredients and their potential synergies, additionally seeking these ingredients may further help support a healthy immune system.
USANA products that contain these immune-supporting ingredients include: USANA’s Vitamin D, BiOmega, Proflavanol C, Poly C, Booster C600, and CellSentials (Vita Antioxidant and Core Minerals).
Proglucamune vs Booster C600
Proglucamune can be taken every day and Booster C600 is best utilized in times when our immune system needs that extra boost.
The active ingredients in Proglucamune include mushroom and yeast extracts and zinc to help support a healthy immune system and scientifically designed to be taken every day.
The active ingredients in Booster C600 include vitamin C, zinc, Black Elderberry, and Echinacea. Both Echinacea and Elderberry have long been used for their beneficial effects on the immune system. With short-term use, Echinacea has been shown to naturally support a healthy immune system. Thus, it is recommended that Booster C600 be used for short periods, generally two weeks or less.
Immune Support MyHealthPak – Which Supplements to Choose?
An “immune support” MyHealthPak would include in each AM and PM packet the CellSentials (2 Core Minerals and 2 Vita AO), 1 BiOmega, 1 Proglucamune, 1 Vitamin D, and 1 Proflavanol C100. This would provide a potent combination of ingredients to help keep my immune system as healthy and strong as possible.
- *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.