CoQuinone® 30: What You Need to Know


Supplement your cells and help them function with antioxidants such as coenzyme Q10, found in CoQuinone®.


When we’re young, our bodies store or produce ample amounts of coenzyme Q10 (CoQ10), which is used by the hundreds of mitochondria in each and every cell to generate adenosine triphosphate (ATP)—the form of energy cells use to function. As we age, the amount of CoQ10 that we absorb or produce naturally declines. In addition, CoQ10 may be depleted by several other factors, including overall nutritional status and inadequate levels of the B vitamins, vitamin C, and selenium. A high-quality, bioavailable CoQ10 supplement, such as CoQuinone 30, can help replenish our cells’ stores of CoQ10, and help hardworking cells, such as those in the heart, stay healthy.*

CoQuinone 30 also provides antioxidant protection. A byproduct of energy production in the mitochondria is the formation of damaging free radicals. Nature has designed a molecule in CoQ10 that is remarkable because it not only assists in ATP production, it also works in concert with other antioxidants to clean up the free radicals that are produced during that process and protect against their damaging effects. As an antioxidant, it rivals vitamins E and C. In addition, CoQ10 helps regenerate and recycle vitamin E.*

This unique supplement combines a well-absorbed form of CoQ10 with alpha-lipoic acid for maximum benefits. A key nutrient involved in converting glucose into energy, alpha-lipoic acid plays many roles in the body and is especially beneficial because it acts like a super antioxidant, going to work both inside the cell and in the outer cell membrane to fight off free radicals. It also assists cells in recycling CoQ10 after it has oxidized to provide even more defense against damaging oxidative stress.*


The energy that every cell needs to function is produced through a complex process in the mitochondria, which are organelles within the cell. Within the mitochondria, cells store energy in a molecule called ATP, which is synthesized and used by every cell in the body. CoQ10 is an essential part of the electron transport chain the mitochondria use to make ATP. CoQuinone 30 dietary supplement was developed to deliver high- quality, highly bioavailable CoQ10 to the cells to support the production of ATP.*

Cells with the highest energy demands, such as in the heart, have the highest levels of CoQ10, which has been studied for years in the United States, Europe, and Japan for its role in producing cellular energy for the heart and other muscles. Several human clinical trials demonstrate CoQ10’s effectiveness in maintenance of good heart function.*


CoQuinone 30 contains a full 30 mg of CoQ10 and 12.5 mg of alpha-lipoic acid per soft gel capsule. USANA’s unique formulation provides these important antioxidants in a natural mixture of lecithin and vegetable- derived glycerin monooleate in a base of medium chain triglycerides. Clinical tests performed in USANA’s laboratories show that CoQuinone 30 delivers CoQ10 in much higher quantities than from solid formulations or from competitive liquid formulations, making CoQuinone 30 more bioavailable than other CoQ10 products.*

CoQuinone 30 contains CoQ10 in the form of ubiquinone. Some competitors use ubiquinol instead, claiming it is a more bioavailable form of CoQ10, but a USANA in-house study confirmed other recently published research showing that both forms are equally beneficial.

CoQuinone contains advanced levels of Coenzyme Q10, a nutrient synthesized and used by every cell in the body due to its essential role in the electron transport chain and ATP production. Coenzyme Q10 has also been shown to support a strong and healthy cardiovascular system, as well as contributing to overall antioxidant protection.

CoQuinone also includes alpha lipoic acid in its highly bioavailable formula.

Coenzyme Q10 Source

The Coenzyme Q10 used in CoQuinone and other USANA products is produced microbiologically in fermentation, then purified.

Ubiquinol or Ubiquinone?

USANA uses solubilized ubiquinone for its CoQuinone products.

There is very little difference in the benefits and bioavailability of ubiquinone and ubiquinol at levels typically provided by dietary supplements. If you read most ubiquinol marketing closely, claims like “ubiquinol is 8 times more absorbable than ubiquinone” often appear. The catch is that this statement is only true when a well-made solubilized form of ubiquinol is compared to a poor form of ubiquinone (either a powder, tablet, or oil gel). In comparison, USANA’s solubilized ubiquinone is also ~8 times more absorbable than powdered and tableted ubiquinone.

Well-formulated ubiquinol and ubiquinone products are not significantly different at dosages normally taken (30-300 mg). It is true to state that at very advanced dosages (several hundred to 3,000 mg), ubiquinol has some advantages – but these dosages are the exception, not the rule. Based on current research and the many papers we have reviewed, the only real difference between ubiquinol and ubiquinone at common dosages is the price and the amount of hype, because the pharmacokinetics of ubiquinol and ubiquinone are virtually identical at these levels.

An in-house review of USANA’s CoQ10 formulation as compared to several competing products:

An in-house review of ubiquinone versus ubiquinol:

An abstract of one of the many papers available on this subject (note the last sentence):

Plasma coenzyme Q10 (CoQ10) response to oral ingestion of various CoQ10 formulations was examined. Both total plasma CoQ10 and net increase over baseline CoQ10 concentrations show a gradual increase with increasing doses of CoQ10. Plasma CoQ10 concentrations plateau at a dose of 2400 mg using one specific chewable tablet formulation. The efficiency of absorption decreases as the dose increases. About 95% of circulating CoQ10 occurs as ubiquinol, with no appreciable change in the ratio following CoQ10 ingestion. Higher plasma CoQ10 concentrations are necessary to facilitate uptake by peripheral tissues and also the brain. Solubilized formulations of CoQ10 (both ubiquinone and ubiquinol) have superior bioavailability as evidenced by their enhanced plasma CoQ10 responses.
Mitochondrion. 2007 Jun;7 Suppl:S78-88

  • *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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