Hepasil DTX™

Love Your Liver and Live the Good Life with USANA® Hepasil DTX™

USANA® Hepasil DTX™

Stay energized and help balance your body’s detoxification processes with a unique liver-support blend made with USANA InCelligence Technology®.

Life comes with the good and the bad. There are memorable meals with loved ones and opportunities to savor delicious food and drink. And there are also inescapable pollutants or chemicals in the environment that are a modern reality. Together, all of these add up to a load of substances your body has to process. Your liver is responsible for filtering everything you consume. It’s a big job. So, your body’s waste filtration system can’t ever really take a break. USANA Hepasil DTX™ can help support the normal health and function of your liver, so it can handle whatever may come its way. And you can stay focused on living the good life.*

The ingredients in Hepasil DTX help support your liver function, which plays many roles in maintaining your daily well-being:

  • Helps your body produce energy through supporting normal metabolic processes*
  • Produces vital substances needed to power your body*
  • Natural removal of fat, toxins, and waste products*

In addition to supporting your liver function, many of the ingredients in Hepasil DTX also provide antioxidant activity to help protect cells from damaging oxidative stress.*

Hepasil DTX is a powerhouse supplement for liver and detoxification support. Hepasil DTX is not a liver cleanse.*

Trendy cleanses where you limit your calories or drink only juices might be a “fun” way to help revitalize your commitment to living a healthier lifestyle. They might even help you lose a couple pounds, but they won’t cleanse your liver. When your liver is healthy, it doesn’t need an extreme cleanse to detoxify. That’s the job it’s designed to do. Hepasil DTX helps provide ingredients that will help it keep doing that job effectively.*

Your liver will love Hepasil DTX because it was formulated with the best of supplement science to create a uniquely powerful formula. It features a number of technologies exclusive to USANA. Each expertly blended tablet features USANA InCelligence Technology to activate your body’s naturally protective detoxification processes. The InCelligence Detox-Support Complex also includes Olivol®–the olive-fruit extract developed by USANA scientists. And because Hepasil DTX is also made with Nutritional Hybrid Technology, it offers an exceptional combination of ingredients at a potency that may not be available in many other products.*

The Liver: Your Body’s Primary Processing Plant

Weighing in at more than three pounds (1.36 kg), your liver is a heavy hitter when it comes to keeping your body healthy. You can find your liver in the upper right area of your abdomen, under your ribs—above your stomach and below the lungs. And, as the second largest organ in your body (your skin is the largest), it performs a multitude of functions vital to keeping you alive and well.

After passing through the digestive tract, almost everything you consume—food, drinks, medications, supplements—goes through your liver. Once there, nutrients are further broken down into forms your body can use. Substances your body needs for energy and other functions are produced and stored. Waste and toxins are filtered out of the blood, then altered, so they can be removed. Once everything is processed, the various compounds are returned to your blood stream. Nutrients and other substances are circulated to where they’re needed. And finally, waste is sent to your bowels and kidneys to be eliminated from your system.

It wouldn’t be too much of an overstatement to say the liver borders on having magical powers. It’s the only organ that can actually regenerate itself when it’s healthy. As long as 25 percent of the tissue remains, your body can essentially re-grow a new liver.

This doesn’t mean you’re free to abuse your liver. Because it’s such a hardworking gland, it’s important to keep it healthy. A number of activities, especially if they’re done excessively, can stress your liver:

  • Drinking too much alcohol
  • Eating too much sugar or fatty foods
  • Misusing medications
  • Using toxin-laden cleaning and gardening products
  • Exposure to high amounts of pollution

There are lifestyle practices you can follow to help maintain your liver function. They include limiting your exposure to excess alcohol, unnecessary chemicals, and fatty foods. Of course, eating plenty of fruits and veggies and getting adequate exercise won’t hurt either. Good hygiene can also help avoid exposing your liver to unnecessary toxins or germs. And drinking enough water will help support the circulation of nutrients and removal of wastes, too. 

You can also help your liver thrive—even in a world filled with toxins and temptations—with advanced daily support. Add USANA’s Hepasil DTX to your healthy lifestyle to help maintain liver function and support your body’s natural detoxification processes.*

Help Your Liver Turn Your Food into Energy with Hepasil DTX

One of the main functions of your almost-magical organ is assisting the digestive process in breaking down everything you consume. This action supplies the energy you need to power your day. Your liver uses many nutrients, including the biotin and choline  in Hepasil DTX, to drive key parts of the metabolism process.*

Your liver uses biotin to form metabolic enzymes. These are substances that cause chemical reactions to break down and change macronutrients, like carbohydrates and protein, into useable compounds. And these biotin-dependent enzymes don’t just break nutrients down. They also help your liver make substances your body needs for energy, like fatty acids and glycogen (a type of sugar your body uses for fuel).*

Choline is used by the body to mobilize many steps of the metabolic process. One of the most important is helping to create phosphatidylcholine (a type of lipid) and betaine (an amino acid), which are vital for helping to move fats and cholesterol out of your liver. This vitamin-like substance is also necessary for supporting normal detoxification reactions.*

Your body can make some choline, but it also needs a steady supply from the diet. And unfortunately, many people don’t eat enough foods with choline. Additional choline could be even more important if you regularly participate in endurance sports (such as triathlons and marathons). Strenuous physical activity has been shown to reduce plasma choline concentrations by about 40 percent.*

Hepasil DTX is an excellent source of biotin and choline to help ensure you have plenty of both nutrients, so your liver can help keep you energized.*

The InCelligence Detox-Support Complex Helps Take Out the Trash

Imagine if you never took the trash out at home. It wouldn’t take long for all of the garbage to build up and become overwhelming. Soon, your home would be run down. And all the debris would interfere with your ability to function optimally.

Your body is similar. The metabolism process is constant source of toxins and waste that are filtered from the substances that you’ve consumed. And your body needs continual maintenance to keep it cleansed. This purification process helps your body function at its best. The liver is a major detoxifying organ that plays the role of housekeeper for your body.*

Taking a supplement like USANA Hepasil DTX every day can help support your liver’s important cleansing function.*

Hepasil DTX delivers superior support for your liver thanks to the InCelligence Detox-Support Complex. The unique blend supplies premium-quality nutrients, including many phytonutrient extracts selected because they deliver the highest percentage of active ingredients. These ingredients support naturally protective processes in a healthy liver.*

Milk thistle (Silybum marianum) extract

The extract in Hepasil DTX is derived from the seeds of the milk thistle fruit. Milk thistle is one of the most frequently used herbal extracts for maintaining the health and function of liver cells. It provides a concentrated amount of the active ingredient silymarin. Recent research revealed silymarin’s benefits may come from its ability to help regulate important cell-signaling pathways for stimulating liver enzymes. And it also promotes the production of your body’s natural antioxidants.*

N-acetyl L-cysteine (NAC)

Hepasil DTX supplements the amount of this amino acid naturally made from L-cysteine in your body. It may be a small protein, but it packs a big punch as a detoxifier. It helps your body make its own glutathione (a powerful antioxidant) to maintain healthy levels in the liver. *

Alpha-Lipoic Acid (ALA)

This acid, which is also naturally produced in the body, is quite the multitasker. Similar to NAC, alpha-lipoic acid helps your body make glutathione. It also offers direct antioxidant activity and helps recycle other antioxidants, including vitamins C and E.*

Historically, ALA could not be combined with NAC, as the two ingredients would break down and lose potency quickly. But because they’re combined using USANA Nutritional Hybrid Technology, these two powerful nutrients can be kept separate to retain potency, but still be delivered in one tablet.*

Broccoli (Brassica oleracea) extract

The broccoli concentrate in Hepasil DTX is a source of powerful compounds from cruciferous vegetables (like glucoraphanin and sulforaphane). They have been studied for their beneficial effects on a number of cell-signaling pathways. One of the effects of these antioxidant compounds is helping to activate the pathways for your body’s natural detoxification enzymes.*

Green-tea (Camellia sinensis) extract

With 90 percent polyphenols, the green tea extract in Hepasil DTX offers concentrated antioxidant activity. One of the most studied antioxidant compounds in green tea is epigallocatechin‐3‐gallate (EGCG). This compound has been shown to regulate important cell-signaling pathways.*

Olivol® olive-fruit (Olea europaea) extract

USANA scientists developed Olivol extract to deliver the potent antioxidant benefits of olive oil in a unique ingredient. The olive-fruit extract helps defend cells from oxidative damage. And research has indicated that hydroxytyrosol, one of the active phenolic compounds in olives, also helps the body produce its own protective antioxidant enzymes.*

Turmeric (Curcuma longa) extract

Turmeric extract is the source of another nutrient you’ve probably heard a lot about: curcumin. The “golden spice of India” has been used for thousands of years as part of Ayurveda (an ancient approach to holistic wellness). More recently, it has garnered a lot of attention. Studies have revealed that curcumin provides many benefits for health, including supporting antioxidant activity and healthy immune responses. Curcumin has also been shown to influence the production of your body’s own antioxidants and help retain normal levels of key detoxification enzymes.*

The InCelligence Detox-Support Complex activates your body’s natural processes to help keep your liver healthy and clear of substances that can slow you down. And by maintaining the integrity of your liver cells with antioxidant protection, the ingredients in Hepasil DTX work together to support the normal function of a healthy liver.*

How Hepasil DTX Helps Your Body Remove Toxins

When it comes to comprehensive support for liver health, Hepasil DTX truly shines. It aids metabolism and the removal of fats and cholesterol from the liver. And the ingredients in Hepasil DTX also help balance natural Phase I and Phase II detoxification reactions.*

Let’s take a brief look at how the process works:

Many enzymes in the liver help change toxins into less harmful substances. The main detoxification pathways in the liver use what are known as Phase I and Phase II enzymes.*

You may have guessed that Phase I is the first stage in your body’s natural detoxification process. Phase I enzymes begin transforming a toxin by joining the toxic molecules with other reactive molecules, making it unstable. This is known as oxidation. Unfortunately, this initial oxidation can make some compounds more toxic. However, your body has a second phase of detoxification that kicks in to defuse the situation.*

In the second phase of detoxification, the highly reactive molecules are combined with various compounds that neutralize them. These are known as Phase II detoxification enzymes. Glutathione, amino acids, and methyl groups are all included in this process (along with other substances). Once the byproducts of Phase I are chained to these water-soluble molecules, the byproducts have been made into forms that can be passed from the body in bile or urine.*

It’s important that Phase I and Phase II detoxification processes are balanced properly. You need Phase I enzymes to start the process. And it’s vital that there are enough Phase II enzymes to ensure the reactive molecules are neutralized to maintain cellular function and support healthy aging.*

That’s where Hepasil DTX comes in. It supplies your body with plenty of nutrients it can use to help keep these natural detoxification reactions in balance.*

Many of the ingredients in the InCelligence Detox-Support Complex, such as turmeric, milk thistle, ALA, and broccoli concentrate, have been shown to support naturally protective processes in the liver. One way they do this is by targeting the cell signaling pathway for helping your body produce liver enzymes, such as glutathione-S-transferase.*

Glutathione is a master detoxifier. It attaches to and carries toxins out of your body. The enzyme is highly concentrated in your liver, because it’s so important to detoxification reactions. And that’s not all. It’s also a master protector.*

Glutathione Guards Healthy Hepatocytes

Glutathione plays many vital roles in your health. In addition to its action as a Phase II detoxification enzyme, glutathione helps the liver regulate lipid, glucose, and amino acid use by the body. And it supports the removal of formaldehyde produced from the metabolism of choline and other substances.

Glutathione also supports healthy hepatocytes (liver cells) by acting as an antioxidant.*

The natural detoxification process is dynamic, with a lot of reactions and conversions happening as substances are metabolized. This process can generate a lot of free radicals. So, enzymes like glutathione can defend against damaging oxidative stress to maintain the health of your liver cells.*

Unfortunately, glutathione from food or supplements is inefficiently absorbed. It’s best to give your body what it needs to make it. In addition to having enough protein from your diet, a number of micronutrients can help support this process.*

The InCelligence Detox-Support Complex contains several nutrients that help your body produce its own antioxidants, like glutathione, in addition to providing antioxidant activity. (Many also help your body make other antioxidant enzymes, like superoxide dismutase [SOD].) Milk thistle, green tea, NAC, ALA, Olivol—virtually every ingredient in the proprietary complex enhances your cells’ ability to generate glutathione to help maintain healthy levels in your liver.*

3 Hepasil DTX a Day Keeps Liver Damaging Free Radicals Away

The InCelligence Detox-Support Complex in Hepasil DTX contains a unique blend of ingredients that optimize cell-signaling pathways tied with glutathione production. This process supports the body’s natural detoxification capacity, and it significantly enhances antioxidant protection.

To test the effectiveness of Hepasil DTX, USANA scientists conducted a double-blind, placebo controlled study. Participants took three tablets a day for 28 days. At the end of the study, USANA researchers looked at antioxidant status by measuring whole blood glutathione and vitamin C levels.*

The study’s results showed that circulating glutathione levels increased following supplementation with Hepasil DTX. And, somewhat unexpectedly, vitamin C levels also increased.

This was surprising, because there isn’t any vitamin C in the product. It was thought that circulating vitamin C levels could only be increased with direct vitamin C supplementation. But the results of this study found that both circulating and tissue levels of vitamin C can also be increased by certain phytochemicals.*

The increases in glutathione and vitamin C were measurable as soon as two hours following the first dose. And the levels continued to stay elevated for at least eight hours, which was when the last measurement was taken.*

To translate the observed increases in glutathione and vitamin C into a benefit, USANA scientists went on to determine the antioxidant capacity of each subject’s blood. They used a Serum Antioxidant Reserve (SAR) test developed by USANA. Results showed that subjects supplemented with Hepasil DTX were significantly more resistant to oxidative damage than subjects given the placebo.*

In other words, Hepasil DTX seriously ramps up your body’s ability to protect your liver, and other cells, from damage caused by free radicals. And because it’s made with USANA Hybrid and InCelligence technologies, no other liver support supplement can equal the innovative formula of Hepasil DTX.*

Key Ingredients

  • Choline
  • Biotin
  • InCelligence Detox-Support Complex

See full list of ingredients

Usage

Adults take three (3) tablets daily, preferably with food.

Ideal For

  • Healthy adults
  • Endurance athletes
  • People exposed to pollution or toxins

Frequently Asked Questions About Hepasil DTX

When should I take Hepasil DTX?

Supporting healthy liver function is always a good idea. But it’s especially important when your body is exposed to increased pollution or when you consume less healthy food and drink. If you know you’re going to need some extra support, it’s best to take Hepasil DTX before the exposure, not after. This will help ensure your liver has the support it needs to keep up with the extra load, when it needs it.*

How does Hepasil DTX affect cell signaling?

Hepasil DTX contains a unique blend of ingredients that alter cell signaling pathways tied with glutathione production. This process increases both the body’s antioxidant and detoxification capacity, by increasing plasma glutathione and vitamin C levels.

References

Newman T. 2018. What does the liver do? Medical News Today [Internet] [accessed 13 Aug 2018] Available at https://www.medicalnewstoday.com/articles/305075.php

How does the liver work? Informed Health Online/PubMed Health [Internet] [accessed 13 Aug 2018] Available at https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072577/

Rui L. 2014. Energy metabolism in the liver. Compr Physiol 4(1): 177-197.

Choline. National Institutes of Health Fact Sheet for Health Professionals. [Internet] [accessed 16 August 2018] Available at https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/

Choline. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. [Internet] [accessed 22 August 2018] Available at https://www.ncbi.nlm.nih.gov/books/NBK114308/

Brown MJ. 2016. What is choline? An essential nutrient with many benefits. Healthline. [Internet] [accessed 22 August 2018] Available at https://www.healthline.com/nutrition/what-is-choline

Cornatzer WE. 1960. Lipotropic agents and lipid transport. Am Jour Clin Nut 8(3): 306-309.

Methionine. PubChem. [Internet] [accessed 22 August 2018] Available at https://pubchem.ncbi.nlm.nih.gov/compound/L-methionine#section=Top

Pajares MA, Pérez-Sala D. 2006. Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism? Cell Mol Life Sci 63(23): 2792-803.

Cho E, et al. 2006. Dietary choline and betaine assessed by food- frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. AJCN 83(4):905-11.

Zeisel S, da Costa K. 2009. Choline: An Essential Nutrient for Public Health. Nutr Rev 67(11): 615-623.

Tong L. 2013. Structure and function of biotin-dependent carboxylases. Cell Mol Life Sci 70(5): 863-891.

Gazak R, Walterova D, Kren V. 2007. Silybin and Silymarin – New and Emerging Applications in Medicine. Current Medicinal Chemistry 14(3):315-38.

Flora S, Pachauri V. 2010. Chelation in metal intoxication. Int J Environ Res Pub Health 7(7): 2745-2788.

Lang I, et al. 1993. Effect of the natural bioflavonoid antioxidant silymarin on superoxide dismutase (SOD) activity and expression in vitro. Biotechnol Ther 4(3-4):263-70.

Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB. 1999. Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis. J Immunol 163(12):6800-9.

Wellington K, Jarvis B. 2001. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs 15(7):465-89.

Esmaeil N, Anaraki SB, Gharagozloo M, Moayedi B. 2017. Silymarin impacts on immune system as an immunomodulator: One key for many locks. Int Immunopharmacol 50: 194-201.

Vargas-Mendoza N, et al. 2014. Hepatoprotective effect of silymarin. World J Hepatol 6(3): 144-149.

de Andrade K, et al. 2015. Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine. Int J Mol Sci 16(12): 30269-30308.

Kall MA, Vang O, Clausen J. 1996. Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcinogenesis 17(4):793-9.

Fahey JW, Talalay P. 1999. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. Food Chem Toxicol 37(9-10): 973-9.

Dinkova-Kostova A, et al. 2002. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A 99(18): 11908-11913.

Yang F, et al. 2001. The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6. Mol Pharmacol 60(3): 528-33.

Oz H. 2017. Chronic inflammatory diseases and green tea polyphenols. Nutrients 9(6): 561.

Basu A, et al. 2013. Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome. Nutr Res 33(3): 180-187.

Chen L, et al. 2017. Therapeutic properties of green tea against environmental insults. J Nutr Biochem 40: 1-13.

Manna C, et al. 1999. Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages. J Nutr Biochem 10(3):159-65.

Echeverría F, Ortiz M, Valenzuela R, Videla L. 2017. Hydroxytyrosol and Cytoprotection: A Projection for Clinical Interventions. Int J Mol Sci 18(5): 930.

Hegazi RA, Seth A. 2013. Chapter 38 – The Role of Curcumin in Gastrointestinal and Liver Diseases. Bioact Food Diet Interv Liv Gast Dis: 585-596. [Internet] [accessed 29 Aug 2018] Available at https://www.sciencedirect.com/science/article/pii/B9780123971548000221

García-Niño WR, Pedraza-Chaverrí J. 2014. Protective effect of curcumin against heavy metals-induced liver damage. Food Chem Toxicol 69: 182-201.

Zhai Qixiao Z, Narbad A, Chen W. 2015. Dietary strategies for the treatment of cadmium and lead toxicity. Nutrients 7(1): 552-571.

Flora S, Pachauri V. 2010. Chelation in metal intoxication. Int J Environ Res Public Health 7(7): 2745-2788.

Hodges RE, Minich DM. 2015. Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application. J Nutr Metab 2015: 760689.

Zimniak P. 2008. Detoxification reactions: relevance to aging. Ageing Res Rev 7(4); 281-300.

Wu G, et al. 2004. Glutathione metabolism and its implications for health. J Nutr 134(3): 489-92.

Oregon State University. Lipoic Acid. [Internet] [accessed 10 October 2018] Available at https://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid

Metabolic Functions of the Liver. Vivo Pathophysiology. [Internet] [accessed 11 October 2018] Available at http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/metabolic.html

American Liver Foundation. 13 Ways to a Healthy Liver. [Internet] [accessed 10 October 2018] Available at https://liverfoundation.org/13-ways-to-a-healthy-liver/

What is Ayurveda. National Ayurvedic Medical Association. [Internet} [accessed 5 November 2018] Available at https://www.ayurvedanama.org/what-is-ayurveda/

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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