USANA® CopaPrime+™

Power Peak Mental Performance with Nootropics in USANA® CopaPrime+™

USANA CopaPrime+

Help your mind focus, learn, and make and recall memories with a boost of brain nutrition made with InCelligence Technology™.*

Life moves fast. To keep pace with daily demands, you need to be at your mental best. But constant disruptions and distractions make it hard to think straight—not to mention dealing with the normal challenges of healthy aging. Help is here. Now, you can maximize your mental performance and protect long-term cognitive health with USANA CopaPrime+.*

The ingredients in CopaPrime+ deliver a boost of brain support. The formula features a potent combination of three naturally-derived nootropics—substances that support peak mental performance. American ginseng works with the InCelligence™ Cognitive-Support Complex—a blend of bacopa and coffee-fruit extract.*

CopaPrime+ nourishes your neurons (a type of brain cell) and increases levels of an important cognitive protein in your body to help deliver important benefits:

  • Support for thinking skills, alertness, and attention that aid learning and retention—even during times of stress*
  • Support for long- and short-term memory*
  • Support for keeping your brain healthy as you age to preserve mental sharpness*

It’s easy to lose focus in an ever-changing world full of packed schedules and pinging smartphones. But it is possible to take control of your cognition and reclaim your concentration.*

Give your brain nutrients that can help you maintain mental clarity, make memories that will last, and enhance your ability to think and learn—even when you’re under pressure. Whether you’re focused on family responsibilities, studying at school, or achieving career success, CopaPrime+ can help your brain keep up with the speed of life.*


Nurture Your Neurons for a Healthy Brain

Your brain performs a multitude of activities every day with the help of many complex functions. All those functions send and receive messages (or cell signals) using neurons to get things done. These messages control conscious and unconscious movements, learning and retention, mood and emotions, memory, your senses, and more.

Your brain and nervous system work like a super speedy postal office. Messages are received, processed, then passed along until they reach their final destination. In the blink of an eye (or less), the message is sent and causes a response.

Those messages mostly travel via specialized cells called neurons. The chemicals made by neurons to carry the messages are called neurotransmitters. These chemicals travel along a nerve fiber called an axon to be passed to the next neuron at a junction called a synapse. The synapses are on the ends of branches called dendrites, which extend from the cell body to receive messages.

Your neurons are some of the longest-living cells in your body. So, keeping them healthy is key to maintaining normal brain function. New neurons can also be created in some areas of the brain, including the hippocampus—the site of learning and memory. But, that’s not the only way your brain can change, which is known in scientific circles as neuroplasticity.

The synapses between neurons can change as they adapt to new information. This is known as synaptic plasticity. That process is directly tied to learning, as it influences how well your neurons communicate with each other. Repeatedly activating synapses makes them stronger, so messages sent between neurons are “louder.”

Over the long term, this synaptic strength plays a role in how well you create and remember new memories.

Many factors can impact the strength and structure of your neurons, which is directly related to your cognitive function. Age, stress, diet, and too little exercise can all cause your brain’s communication pathways to work less efficiently.

Fortunately, there are many lifestyle habits you can adopt to support brain health and cognitive function:

  • Feed your brain a calorie-conscious, healthy diet
  • Exercise (include yoga and vigorous 35- to 40-minute cardiovascular workouts)
  • Learn new things
  • Get plenty of sleep
  • Meditate
  • Stay connected with friends

Supplements can also help provide fuel for your mind. Many nutrients in CellSentials and HealthPak have been linked to maintained brain health. This includes choline, coenzyme Q10, green tea, resveratrol, quercetin, and curcumin. Lutein, which is found in Visionex, supports strong neuron signals. And, BiOmega provides omega-3 fats to help keep brain cells fluid and functioning optimally.*

Targeted supplementation with nootropics, such as those in USANA CopaPrime+, can also be added to these healthy lifestyle habits to help promote peak mental performance.*


CopaPrime+ Was Designed With Your Brain In Mind

When your brain can maintain strong connections, it’s primed to help you learn, concentrate, and make and recall memories. CopaPrime+ was designed with nootropics that help strengthen those connections by supporting your neural pathways’ ability to fire and wire together*

Take a closer look at the nootropics in USANA CopaPrime+.

American Ginseng

CopaPrime+ contains a potent extract of American ginseng (Panax quinquefolius). It is cultivated to deliver optimum levels of specific neuroprotective compounds (primarily ginsenosides Rg1, Rb1) to ensure effective cognitive benefits.*

Ginseng supports healthy brain function in a number of ways.*

First, it can influence healthy function of the cholinergic system. This is how your brain converts the nutrient choline into acetylcholine (ACh)—an important neurotransmitter that sends messages in the nervous system. ACh plays a role in learning, attention, and the formation of short- and long-term memory by supporting synaptic plasticity and communication.*

Ginseng is also beneficial to brain health because it acts as an antioxidant. In this way, it helps protect neurons and neurotransmitters from damaging oxidative stress.*

The herb has been used for centuries in Chinese culture to help manage occasional stress, enhance mental clarity, and promote soothing Yin energy (instead of invigorating Yang energy). Science supports these benefits. Research has shown ginseng can support a positive mood, tranquility, and mental energy.*

InCelligence Cognitive-Support Complex

The ingredients in the InCelligence Cognitive-Support Complex support a new approach to brain health. They help your body naturally increase levels of an important cognitive protein called brain-derived neurotrophic factor (BDNF).*

BDNF is one of four types of neurotrophins. These proteins control the survival, development, function, and maintenance of neurons. BDNF is found throughout the brain, including in the hippocampus. There, it supports many signaling pathways involved with neuroplasticity, including those for:

  • making new neurons
  • dendrite density (it’s better to have a lot of dendrites)
  • and synaptic strength and plasticity

Maintaining adequate levels of BDNF in the brain and body is critical for normal cognitive and nervous system function.*

Learning, mood, focus, and memory all rely on this important protein. And production of BDNF decreases as you get older, if you’re stressed, don’t exercise enough, or gain weight. But you can’t take BDNF to increase it, because it isn’t a very bioavailable ingredient.*

The good news is targeted nutrients can stimulate your body to make BDNF naturally. Two of these nutrients make up the InCelligence Cognitive-Support Complex in CopaPrime+.*


Bacopa monnieri (also known as brahmi or water hyssop) is an herb that’s been used for thousands of years in Ayurveda—the holistic approach to health practiced in Indian culture. There are even reports bacopa may have been used in India between 1500 and 1000 B.C. to help scholars memorize lengthy hymns. So, it’s also long been used to sharpen intellect.*

The naturally-derived extract used in CopaPrime+ has the highest amount of Serotonin Active Bacopa Glycosides. This simply means it targets cell receptors that play a major role in cognition, while also supporting a sense of well-being. *

That’s not all. In addition to increasing BDNF to nourish and restore neurons, bacopa has been shown to support the production of ACh for normal cell signaling, which is key for learning and memory. It’s also an antioxidant and can act as an adaptogen—a substance that helps your body handle the effects of occasional stress.*

Whole Coffee-Fruit Extract

The health benefits of coffee go beyond the beans you brew. The cherry fruit that those beans come from also offers valuable nutrients when harvested and processed properly. The natural coffee fruit (Coffea arabica) in CopaPrime+ is extracted using a proprietary process that preserves high levels of chlorogenic acid (a source of polyphenols). But it has low amounts of caffeine.

The unique phytonutrient profile of this coffee extract makes it more active in the body. This potency is thought to be the reason it can increase BDNF levels. The extract also offers antioxidant activity for added protection for your brain cells.*

The coffee extract in CopaPrime+ is sourced from farms certified by Rainforest Alliance, an organization committed to sustainable practices.

The above active ingredients in USANA CopaPrime+ offer benefits for your day-to-day life and also can help keep your brain healthy as you age. And, the effects occur quickly. The ingredients have been shown to increase levels of BDNF in as little as one to two hours. Continued use creates even stronger effects. Research on bacopa has shown maximum impact between six and 12 weeks.*


CopaPrime+ is a Brilliant Way to Have a Brighter Day

CopaPrime+ is an easy way to get a daily boost of brain nutrition for studying or performing your best at work. It’s designed to support three key areas for developing your brain and dominating your day: concentration, learning and retention, and staying cool under pressure.*


Distractions make learning more difficult and may lead to ineffective cramming sessions to catch up. And they can wreak havoc on your productivity. Technology, with all its amazing advantages, also brings information overload that can leave you feeling frazzled and scatterbrained.

When you need to focus, it’s important to be able to tune out the world, quiet the mind, and get things done.

Schedules, adequate sleep, a quiet environment, or a good pair of noise-cancelling headphones are all good strategies to help you focus. And, taking CopaPrime+ every day can help make it easier to stay alert and focused—no headphones required.*

The ingredients in CopaPrime+ have been shown to help selective attention—which is the ability to direct your awareness and ignore distractions. This means you can concentrate on whatever you need to pay attention to. CopaPrime+ also supports speed of attention, so you can get into your deep-thinking work more quickly. There’s even evidence bacopa may help you work faster—and who doesn’t want to get more done in less time?*

Learning and Memory

Faster work is the result of improved processing speed—the time it takes to do a mental task. CopaPrime+ supports information processing, learning, and retention to enhance your thinking skills. These are the skills you’ll use for any mental task, whether you’re tapping into your creativity for a writing project, evaluating a math problem, or analyzing data.*

Another key aspect of healthy mental performance is your short-term memory. Your brain must hold information long enough to form connections that will lead to true understanding. This is called “working memory.”

This type of memory is important for reasoning, decision-making, behavior, learning, and comprehension. You use your working memory to retain information in many situations, including:

  • Reading a book, article, or blog
  • Watching a video, movie, or TV show
  • Listening to a lecture
  • Working through calculations
  • Following instructions
  • Repeating a phone number after hearing it
  • Planning a driving route
  • Finding your keys

As new information comes in, it combines with information already in your working memory. This combination makes the information useful. You’ve followed the plot, learned something new, or solved a problem by putting the pieces together.

The ingredients in USANA CopaPrime+ have shown benefits for working memory and learning.*

Here’s one example: In a randomized, placebo-controlled trial, a group of 60 medical students took bacopa (300 mg) for six weeks. At the end of the study, measures of working memory, immediate recall of logical material, and language comprehension improved. Positive effects were also seen in efficiency of attention and freedom from distractibility.*

Stress Without Duress

Now, with the help of CopaPrime+, you’ve helped your brain focus and prepare to learn. But, another important factor could impact your ability to maximize your mental game: stress. CopaPrime+ can assist with that, too. That’s because this brain supplement can also help you manage the mental effects of occasional stress.*

When you start feeling the tension of demands and daily pressures, CopaPrime+ can help you stay cool, calm, and collected. Study participants have self-reported feeling less tense and more composed after using the ingredients in CopaPrime+. This is likely because the ingredients support systems in your body that influence positive mood and its ability to handle stress.*

If you’re under occasional stress and feeling overwhelmed, CopaPrime+ will help relax and focus your mind. Get additional support for your body with USANA’s Proglucamune immune-support supplement to promote daily well-being.*

Study Shows Immediate Benefits of CopaPrime+

A double-blind, placebo-controlled research study showed support for three cognitive measures only 45 minutes after participants took a single dose. Mental efficiency, accuracy, and response times during mentally demanding tasks were all impacted. Take a closer look at the exciting results of this study.*


Stay Sharp With CopaPrime+ and Remember Moments That Matter Most

Gaining wisdom is one of the greatest advantages of aging. Your knowledge and insights can help make middle-age and beyond the best years of your life. It’s important to protect your mental performance, so you can remember the things that mean the most as you continue to learn and grow.*

If you feel like you don’t think as quickly as when you were younger, that’s normal—even if you’re in your thirties. There’s some question about when mild, age-related declines in cognitive function generally start. One 2009 study reported structural changes in the brain as early as your twenties. But, generally, research points to mid-life—your fifties and older—as the time when signs of mild cognitive decline associated with normal aging become more apparent.

The cognitive functions most affected during healthy aging are speed of information processing, memory, spatial ability (related to remembering and visualizing images), and reasoning. CopaPrime+ can help you maintain a healthy brain and nervous system, which are key to preserving mental sharpness and cognitive function as you age.*

Research on the ingredients in CopaPrime+, specifically in adults over 40, has shown benefits for learning, as well as short- and long-term memory. Benefits have been observed for the following measures after up to four months of supplementation:*

  • Verbal learning (repeating lists of words)
  • Retention of new information
  • Focus and attention
  • Processing speed
  • Short-term or working memory
  • Making memories
  • Long-term memory

CopaPrime+ can help support these functions of mental acuity by helping restore healthy levels of BDNF in your body. As you read above, BDNF is a protein that helps keep your neural networks strong and stable. And, higher levels in the brain have been associated with better maintained cognitive function later in life. *

CopaPrime+ also protects normal cognitive processing and memory. It does this by maintaining a healthy balance of neurotransmitters, including acetylcholine (ACh). This keeps information flowing throughout your brain.*

Antioxidant activity also plays a role in the brain supplement’s neuroprotective effectiveness. This activity is important because your brain cells are particularly vulnerable. To function properly, neurons need oxygen, glucose, and fatty acids, which are susceptible to attacks from free radicals. So, by neutralizing oxidative damage, USANA CopaPrime+ protects long-term neural and cognitive function.*


Key Ingredients

  • American ginseng
  • InCelligence Cognitive-Support Complex (bacopa and coffee extract)

See full list of ingredients


Adults, take two (2) tablets daily, preferably with food.

Ideal For

  • All healthy adults over age 18
  • College students
  • Career-focused professionals
  • Mature individuals interested in maintaining mental performance and memory

Frequently Asked Questions About CopaPrime+

CopaPrime+ was not designed for use by children. The labeled dosage on CopaPrime+ is appropriate for adults over 18.

The ingredients in CopaPrime+ have been used in numerous clinical studies and tolerated well. Some study participants who consumed doses higher than those provided in CopaPrime+ experienced mild headache or digestive upset, which went away naturally. If you experience a side effect after taking CopaPrime+, try taking it with food and reducing the dose to one tablet a day, then gradually returning to the full dose, as tolerated.

There are trace amounts of caffeine from the natural coffee-fruit extract in CopaPrime+.

CopaPrime+ and Ginkgo-PS both offer antioxidant protection. Otherwise, they work through different activity in the brain. Ginkgo-PS works by increasing blood flow, which is important for delivering oxygen and nutrients to the brain. And the phosphatidylserine (PS) is a compound that helps nerve cell membranes stay fluid, so that messages are sent and received effectively. CopaPrime+, on the other hand, works primarily by helping your body make an important protein for cognition, memory, learning, and focus. Because they work by different mechanisms, there should be no reason you couldn’t take them together. However, please note that CopaPrime+ will be replacing Ginkgo-PS, which will be phased out of production as supplies run out.

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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