Support Your Skin’s Natural “Glow”


Your face is your most visible expression of self. It’s a canvas of emotion, identity, and connection. It’s where joy, stress, and time leave their mark.

While skin is often viewed through a cosmetic lens, its health is deeply rooted in cellular function. Beneath the surface, a complex network of skin cells works tirelessly to maintain resilience, hydration, and repair. Yet as we age, the skin’s natural radiance can be challenged by environmental stressors, oxidative damage, and a gradual decline in cellular function.

By targeting the biological processes, USANA Glow offers a science-backed approach to nurturing facial skin at the deepest level.

The Benefits of Glow


Glow is formulated with powerful antioxidants and skin-nourishing ingredients to support even skin tone, hydration, and overall skin health from within.


Glow is an oral supplement designed to support skin at the cellular level. Each nourishing ingredient helps support not just your skin’s health, but the feeling of vitality and confidence that radiates from truly thriving skin.

  • Glow includes clinically studied ingredients that are shown to support even skin tone, pigmentation, and radiance.*
  • The ingredients in Glow sustain skin health by providing antioxidant support for the skin’s cells, which helps maintain cellular function by neutralizing free radicals and reducing oxidative *
  • Glow includes omega-6 and omega-9 fatty acids to support moisture production in the skin and maintain a healthy skin barrier.*

Damasty Shows Benefits through Clinical Study


Robertet’s clinical study shows that Damasty’s blend of rose extract, melon juice SOD, and acerola extract supports even skin tone and radiance, and helps strengthen skin’s antioxidant defenses and support overall skin health within just a few months.*


Robertet’s Damasty formula combines rose extract, melon juice SOD, and acerola extract. In a clinical study involving more than 160 women, Robertet researchers evaluated Damasty and observed promising results, highlighting its potential benefits as used in USANA Glow.

  • Rose extract was shown to support antioxidant defenses in the skin in as little as one day.
  • Within one month, melon juice concentrate, rich in superoxide dismutase (SOD), supported the skin’s antioxidant defenses and helped protect against oxidative stress.
  • The full Damasty formula with rose extract, melon juice SOD, and vitamin C from acerola extract supported antioxidants and helped support overall skin health at two and three months.

These promising results highlight the potential of Damasty’s unique blend of natural extracts included in Glow to support even pigmentation, skin tone, and radiance.*

Carotenoids and Powerful Antioxidants


Glow features astaxanthin, a powerful antioxidant from microalgae that supports skin elasticity and hydration.


Glow contains astaxanthin, a carotenoid obtained from microalgae and creatures that eat microalgae, such as salmon, shrimp, and krill. Astaxanthin is the chemical that gives these creatures their orange/pink/red colors.

As a powerful antioxidant, Astaxanthin provides several benefits for skin health—but will not turn you pink. On the contrary, this potent carotenoid supports even skin tone. It also helps maintain healthy skin by supporting skin elasticity, enhancing skin hydration, and supporting overall skin health. Additionally, astaxanthin can protect against oxidative stress.*


Grape Seed Oil—Linoleic Acid and Oleic Acid


Glow’s grape seed oil delivers essential fatty acids like linoleic and oleic acid to help strengthen the skin barrier, lock in moisture, and support hydration, elasticity, and overall skin health.


Grape seed oil is a fatty oil rich in linoleic acid with a moderate amount of oleic acid. Linoleic acid, an omega-6 fatty acid, is essential for maintaining the skin barrier—the top layer of skin that protects against harmful substances while retaining essential moisture and nutrients.*

Oleic acid, an omega-9 fatty acid, also contributes to grape seed oil’s moisturizing properties by locking in moisture and enhancing the absorption of beneficial compounds such as linoleic acid. These benefits make grape seed oil an ideal ingredient in Glow to promote skin health and hydration.*

Add Glow to Your Celavive Skin Routine


Glow is powered by Celavive to complement topical skincare by nourishing skin cells from within to help maintain a radiant, youthful complexion.


USANA Glow is powered by Celavive, the high-performance skincare line designed to support skin health at the cellular level. Celavive contains nutrient-rich ingredients to help rejuvenate and protect the skin, particularly targeting signs of aging such as wrinkles, dryness, and loss of elasticity.

While traditional skincare routines commonly rely on topical creams, lotions, and gels that act on the skin’s surface to enhance the appearance of healthy skin, Glow offers a complementary approach that works from within. Rather than replace your existing regimen, Glow becomes an essential step toward nourishing your skin’s cells and helping maintain a radiant, healthy complexion from the inside out.

Help Your Skin Glow!


From Damasty to grape seed oil, the ingredients in Glow support your skin through powerful antioxidants, vitamins, and nutrients. These ingredients help maintain even skin pigmentation, tone, and radiance, and support overall wellness from the inside out through the systemic benefits of an oral supplement.*

Key ingredients

  • Damasty
    • Rose extract
    • Melon extract
    • Acerola fruit extract
  • Astaxanthin
  • Grape seed oil

Usage

Take one (1) capsule daily, preferably with food.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

https://www.robertet.com/en/accueil-en/

https://examine.com/supplements/astaxanthin/?show_conditions=true

https://pmc.ncbi.nlm.nih.gov/articles/PMC6098779/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3917265/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4988453/

https://pubmed.ncbi.nlm.nih.gov/23278117/

https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/

https://www.robertet.com/en/accueil-en/

https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/grapeseed-oil

Experience the energizing benefits of USANA Revolve Fizzy Energy Drink in convenient, ready-to-mix stick packs. It’s the perfect boost to take wherever you go. Simply mix with water, let it fizz, and enjoy this fresh alternative to the typical energy drink.

USANA Revolve Fizzy Energy Drink is formulated without artificial flavors, artificial sweeteners, and artificial colors. None of the stuff you don’t want, all while delivering the energy drink benefits you’re looking for.

It’s formulated to give you:

  • Physical and mental invigoration with naturally sourced caffeine
  • B vitamins for energy metabolism
  • Electrolytes for physical performance and to support healthy hydration

Stimulate Your Mind and Body

Naturally sourced caffeine can help you feel alert, focused, and have improved energy levels. And USANA Revolve Fizzy Energy Drink contains about 60 mg of caffeine, as much as an average cup of tea or a small cup of coffee.

Caffeine is a stimulant consumed regularly in coffee, tea, and soft drinks. It works by blocking the effects of adenosine, a neurotransmitter that makes you feel relaxed and tired. When caffeine takes its place—effectively blocking the adenosine—your brain and nervous system do the opposite. It’s how the caffeine in USANA Revolve Fizzy Energy Drink helps to rev up your central nervous system.

Essential Nutrients for Physical Performance

Sodium and potassium are two important minerals that help your body function properly. Your cells use them to help transmit nerve impulses and contract muscles. Without these minerals, your muscles can’t contract properly—and too little in your body can lead to muscle weakness and cramps.

USANA Revolve Fizzy Energy Drink can keep your muscles in shape by helping you stock up on potassium and sodium. And its essential nutrients don’t stop there. Each sip also helps to give you the B vitamins you need to turn the food you eat into energy.

B vitamins are a group of essential nutrients that play a variety of roles in the body, including energy production. Your body can’t engage in energy metabolism without sufficient levels of B vitamins. Extra B vitamins aren’t going to boost your energy to infinitely higher levels. But if you don’t get enough of any one of these vitamins, you may experience fatigue, weakness, or have difficulty concentrating.

USANA Revolve Fizzy Energy Drink brings together B vitamins to help keep your body ready to produce energy. Then sodium and potassium make sure your muscles can use that energy on demand.

Finally, it includes Chromium, which is a trace mineral that binds to amino acids and other compounds to create Glucose Tolerance Factor (GTF). GTF allows insulin to bind to receptors on the surface of cells, enhancing the uptake of glucose from the blood. That’s how chromium helps maintain healthy blood sugar already in the normal range.

It’s not just glucose, though. Chromium also takes part in metabolizing proteins, fats, and carbohydrates. So, it helps turn the macronutrients of your diet into useful cellular energy.

Electrolytes to Help Keep You Hydrated

In addition to nerve transmission and muscle contraction, sodium and potassium also play a vital role in keeping you hydrated. These key electrolytes help balance the amount of water inside and outside each of your cells.

When you sweat, you aren’t losing just water, you also lose sodium and some potassium. Too little of these minerals can affect your body’s ability to retain water and lead to dehydration.

Electrolyte replacement drinks are a great way to maintain a healthy balance of electrolytes in your body. USANA Revolve Fizzy Energy Drink adds sodium and potassium to your water for an easy, convenient, and delicious way to replace electrolytes.

Support Energy and Physical Performance with Ginseng and Taurine

Both ginseng and taurine have established themselves as popular ingredients in energy supplements and foods. Ginseng can be traced back hundreds of years as a popular herb used in traditional Chinese medicine to help strengthen and revitalize the body’s qi. [https://askthescientists.com/traditional-chinese-medicine/] More broadly it has been shown to support physical and mental energy levels, support cognitive function, help the body cope with stress, and is an antioxidant.

Taurine has more modern origins. It’s synthesized in the body and consumed in the diet in small amounts, but taurine in foods has only become popular in the last few decades. When combined with caffeine, as found in USANA Revolve Fizzy Energy Drink,  it’s been shown to support athletic performance.

Key Ingredients

Caffeine (from Green Tea)

Sodium

Potassium

Vitamin B2 (as Riboflavin)

Vitamin B3 (as Niacin)

Vitamin B5 (as Calcium Pantothenate)

Vitamin B6 (as Pyridoxine HCl)

Vitamin B12 (as Cyanocobalamin)

Chromium (as Chromium Polynicotinate)

Korean Ginseng

Taurine

 

See full list of ingredients

 

Directions

Add one (1) stick pack to 8 fl. oz. (235 mL) of water, stir, and enjoy.

 

Ideal For

Adults looking to support their body’s natural energy cycle.

 

 

Q. Do the carbonates and bicarbonates offer any buffering potential in the stomach or body.
A. No. They are fully neutralized from the citric acid included in the formula.

Q. How do Korean ginseng and American ginseng compare?
A. Korean ginseng is known for its stimulating effects and is often used to support physical and mental performance. American ginseng is known for its calming effects and is often used to help manage stress, and support sleep.

Q. What creates the green color of Revolve Fizzy Energy Drink?
A. Revolve Fizzy Energy Drink does not have any added colors. The green color of the product is naturally occurring, primarily coming from Korean ginseng and riboflavin.

 

Souza DB, Del Coso J, Casonatto J, Polito MD. Acute effects of caffeine-containing energy drinks on physical performance: a systematic review and meta-analysis. Eur J Nutr. 2017;56(1):13-27.

Waldron M, Patterson SD, Tallent J, Jeffries O. The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis. Sports Med. 2018;48(5):1247-1253.

Chen Q, Li Z, Pinho RA, et al. The Dose Response of Taurine on Aerobic and Strength Exercises: A Systematic Review. Front Physiol. 2021;12:700352.

Hansen SH, Andersen ML, Cornett C, Gradinaru R, Grunnet N. A role for taurine in mitochondrial function. J Biomed Sci. 2010;17 Suppl 1(Suppl 1):S23.

Von Duvillard SP, Braun WA, Markofski M, Beneke R, Leithäuser R. Fluids and hydration in prolonged endurance performance. Nutrition. 2004;20(7-8):651-656.

USANA Marine Collagen Peptides Convenient for On-the-go Lifestyle

Collagen is the most common protein in your body. It’s found in your bones, muscles, tendons, ligaments, and, of course, skin. Caring for the collagen in your body will reflect positively on your overall health. USANA Marine Collagen Peptides provides a convenient method to nurture your body’s collagen to maintain healthy skin and joints no matter what your daily routine looks like.*

This remarkable collagen supplement comes in a gel form for quick and efficient absorption of active ingredients. Simply tear off the tab and enjoy the delicious pomegranate citrus flavor—no need to mix with food or liquid. The ready-to-drink sachet fits perfectly in your purse, glovebox, or backpack, making it the perfect on-the-go collagen supplement.

Marine Collagen Peptides is made using collagen from fish—specifically Atlantic and Pacific cod. Marine collagen is a versatile compound capable of offering many benefits including:

  • Sustaining healthy skin including hydration and elasticity*
  • Maintaining joint strength and flexibility*
  • Neutralizing free radicals through antioxidant properties
  • Absorbing more easily into the gastrointestinal tract and into the bloodstream to effectively reach collagen fibers
  • Aligning with dietary restrictions by providing an option besides bovine collagen

Transform your skincare routine with a powerful foundation of nutrition that starts beneath the surface to sustain healthy, glowing skin.

Support Your Healthy Collagen Throughout your Body with Type I Collagen Peptides

Drinking a daily collagen supplement can help your skin feel healthy and revitalized. Marine Collagen Peptides supports skin health and helps combat visible signs of aging, including natural smoothness and bounce by promoting elasticity and hydration.* Marine collagen supports moisture retention to address loose and lackluster skin.* Fine lines and wrinkles are no match for a healthy dose of collagen supplement.

Similarly, Marine Collagen Peptides supports joint health by supporting the skin, bones, tendons, and ligaments and maintaining the integrity of structures around the joints. Supporting collagen to sustain healthy skin and joints is possible because of the collagen peptides in this supplement.*

USANA Marine Collagen Peptides relies on types I collagen peptides. Collagen peptides (or protein chains) create strong connective tissues and give your skin and cartilage its shape and structure. They’re also responsible for your skin’s elasticity, or stretchiness.

Collagen is the most abundant protein in your body, but its natural production declines over time. This often leads to your skin and joints showing visible signs of aging. That’s why a supplement like USANA’s Marine Collagen Peptides helps support the appearance of youthful skin and maintain healthy joints.*

More Ingredients to Enhance the Marine Collagen Peptides Experience

Marine collagen already contains a plethora of benefits to support your skin and joint health including elasticity, hydration, and more. Included with Marine Collagen Peptides are fruit powders and concentrates for increased phytonutrients (natural compounds found in plant-based foods like fruits, vegetables, grains, beans, nuts, and seeds). Cranberry juice, apple juice, acerola cherry powder, elderberry juice, wolfberry powder, and green tea powder were provide antioxidant support that can support healthy skin and healthy joints.*

Collagen On-the-go or Shared with Friends

One of the favorite parts of Marine Collagen Peptides is its easy-to-share packaging. One sachet can support your collagen, so why not bring along another to share with a friend? No preparation or mixing is involved. Simply remove the top and drink the gel formula. This thoughtful gesture can help keep you and your friends healthy as you share in the benefits of healthy collagen.

While Marine Collagen Peptides, with its pomegranate citrus flavor, is ready at a moment’s notice, some customers have suggested drinking them cold for enhanced flavor. No matter how you enjoy your daily dose of collagen—cold, room temperature, alone, or with a friend—what’s important is that you are supporting your collagen’s health and wellness.

USANA Marine Collagen Peptides—Create Beauty On-the-go

Your skin is your way of showcasing the beauty within you. Treat your collagen to a delicious and effective skin-health optimizer with a daily drink of USANA Marine Collagen Peptides.* You’ll look your best and feel confident with the support of high-quality nutrition that helps your skin radiate health and brilliance, and your joints maintain their structure and flexibility.

Key Ingredients

  • Marine collagen
  • Phytonutrient-rich ingredients: cranberry juice, apple juice, acerola cherry powder, elderberry juice, wolfberry powder, and green tea powder

See full list of ingredients

Usage

Shake well before drinking and drink immediately after opening the pouch. Recommended to drink cold for better taste. Additional pouch may be taken if desired. Do not drink if pouch is swollen or seal is broken.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Bolke, L., Schlippe, G., Gerß, J., & Voss, W. (2019). A collagen supplement improves skin hydration, elasticity, roughness, and density: Results of a randomized, placebo-controlled, blind study. Nutrients, 11(10), 2494.

Borumand, M., & Sibilla, S. (2014). Daily consumption of the collagen supplement Pure Gold Collagen® reduces visible signs of aging. Clinical interventions in aging, 1747-1758.

Al-Atif, H. (2022). Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics. Dermatology Practical and Conceptual, 12 (1), 1–10.

Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral collagen supplementation: a systematic review of dermatological applications. J Drugs Dermatol, 18(1), 9-16.

Hexsel, D., Zague, V., Schunck, M., Siega, C., Camozzato, F. O., & Oesser, S. (2017). Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Journal of cosmetic dermatology, 16(4), 520-526.

FAAD, G. A. M. (2018). A six-month, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of a nutraceutical supplement for promoting hair growth in women with self-perceived thinning hair. Journal of Drugs in Dermatology, 17(5), 558-565.

Ablon G. (2015). A 3-month, randomized, double-blind, placebo-controlled study evaluating the ability of an extra-strength marine protein supplement to promote hair growth and decrease shedding in women with self-perceived thinning hair. Dermatology research and practice, 2015, 841570.

De Luca, C., Mikhal’chik, E. V., Suprun, M. V., Papacharalambous, M., Truhanov, A. I., & Korkina, L. G. (2016). Skin antiageing and systemic redox effects of supplementation with marine collagen peptides and plant-derived antioxidants: A single-blind case-control clinical study. Oxidative medicine and cellular longevity, 2016.

Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo‐controlled clinical trials. Journal of cosmetic dermatology, 14(4), 291-301.

Evans, M., Lewis, E. D., Zakaria, N., Pelipyagina, T., & Guthrie, N. (2021). A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. Journal of cosmetic dermatology, 20(3), 825-834.

Venkatesan, J., Anil, S., Kim, S. K., & Shim, M. S. (2017). Marine fish proteins and peptides for cosmeceuticals: A review. Marine drugs, 15(5), 143.

Maia Campos, P. M. B. G., Franco, R. S. B., Kakuda, L., Cadioli, G. F., Costa, G. M. D. A., & Bouvret, E. (2021). Oral supplementation with hydrolyzed fish cartilage improves the morphological and structural characteristics of the skin: A double-blind, placebo-controlled clinical study. Molecules, 26(16), 4880.

Sangsuwan, W., & Asawanonda, P. (2021). Four-weeks daily intake of oral collagen hydrolysate results in improved skin elasticity, especially in sun-exposed areas: A randomized, double-blind, placebo-controlled trial. Journal of Dermatological Treatment, 32(8), 991-996.

Stephens, T. J., Sigler, M. L., Hino, P. D., Le Moigne, A., & Dispensa, L. (2016). A Randomized, double-blind, placebo-controlled clinical trial evaluating an oral anti-aging skin care supplement for treating photodamaged skin. The Journal of clinical and aesthetic dermatology, 9(4), 25.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8780088/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11050892/

https://www.nytimes.com/2019/11/09/style/self-care/collagen-benefits.html

Promote Healthy Circulation with USANA Circulate+

Maintaining healthy circulation is important to your cardiovascular health and overall wellbeing. A healthy diet, regular exercise, and wholesome habits can affect good blood flow. For an extra boost, USANA Circulate+ drink mix can provide you with ingredients rich in nitric oxide (NO), sustaining circulation and overall cellular health.

Circulate+ enhances nitric oxide production to promote the following:

  • Vasodilation: “Vaso” refers to blood vessels and “dilation” means widening. Therefore, vasodilation refers the widening of blood vessels, allowing more blood to flow through them. NO helps with vasodilation by relaxing and widening blood vessels, improving blood flow and reducing blood pressure.
  • Immune Response: NO helps support robust immune function and a healthy immune response.
  • Antioxidant Effects: NO helps protect blood vessels from oxidative stress and free radical damage.
  • Exercise Performance: Increased NO can help blood flow and oxygen delivery to muscles, improving performance and reducing muscle fatigue.
  • Neurotransmission: Effective neurotransmission is important for brain function and overall nervous system health. NO can act as a neurotransmitter, facilitating communication between neurons (nerve cells).
  • Wound Healing: NO supports various aspects of wound healing, including inflammation.
  • Maintaining Healthy Inflammation: By helping your body maintain a normal and healthy inflammation within the vascular system, nitric oxide supports cardiovascular health and maintains arterial health.

The nitric-oxide rich ingredients in Circulate+ can help you sustain performance and support overall health. But what is nitric oxide and how is it produced in your body?

The Benefits of Increased Nitric Oxide in the Body

Nitric oxide is a free radical characterized by an unpaired electron, which makes it highly reactive. Unlike most free radicals that are neutralized by antioxidants to prevent cellular damage, NO is unique due to its essential roles in the body. It is considered the body’s only known healthy free radical because of its positive effects on various physiological processes.

Nitric oxide is a molecule composed of one nitrogen atom and one oxygen atom. The body produces NO through two main pathways:

  1. Reducing dietary nitrates to nitrites and then to nitric oxide, especially under low oxygen conditions such as during intense physical activity.
  2. Converting the amino acid L-arginine into nitric oxide using the enzyme nitic oxide synthase (NOS)

The ingredients of Circulate+ utilizes both these pathways to support your body’s natural ability to produce nitric oxide.

Support Nitric Oxide Production with Red Spinach Extract

Nobody understands the benefits of spinach quite like the character Popeye. While consuming spinach will not have the same instantaneous results as portrayed by the cartoon sailor, spinach offers several benefits that apply to reality.

Leafy greens like spinach are excellent sources for boosting nitric oxide levels. The body converts the compounds in spinach into nitric oxide through the following process.

  1. Nitrate (NO3): Nitrate is a compound with one nitrogen atom and three oxygen atoms. When consumed, nitrates are absorbed in the gut and concentrated in the salivary glands.
  2. Nitrite (NO2): Bacteria in the mouth convert nitrates in the salivary glands to nitrites, which are compounds with one nitrogen atom and two oxygen atoms. These nitrites are then swallowed with saliva.
  3. Nitric Oxide (NO): The acidic environment of the stomach reduces nitrites to nitric oxide which can then enter the bloodstream and exert its various physiological effects, such as maintaining blood flow and supporting cardiovascular health.

The red spinach extract in Circulate+ is included for its high nitrate content. The increased nitric oxide levels from the red spinach extract can help support endurance, athletic performance, and muscle growth and recovery.

Convert Nitrates to Nitric Oxide with L-arginine

The body also produces nitric oxide through the enzyme nitric oxide synthase (NOS) using the amino acid L-arginine. A synthase is an enzyme that joins two molecules together—in this case, L-arginine and molecular oxygen—to form nitric oxide. This process takes place throughout the body and involves three main distinct forms called isoforms:

  • Endothelial NOS (eNOS): Found in the cells lining blood vessels, eNOS regulates blood pressure, blood flow, and causes vasodilation.
  • Neuron NOS (nNOS): Found in the nervous system including brain and peripheral nerves, nNOS helps with neurotransmission, synaptic plasticity (the ability of neurons to change the strength of their connections which plays a key role in memory storage), and regulation of blood flow in the brain.
  • Inducible NOS (iNOS): Found in various cell types, particularly immune cells, iNOS helps support strong immune cells and regulate normal inflammatory responses.

L-arginine is considered semi-essential, meaning that while the body can produce it, additional amounts may be needed from dietary sources or supplements. Circulate+ is one such supplement that can provide additional L-arginine to support nitric oxide production.

Maintain Health with Antioxidants from Grape Seed Extract

The benefits of grape seed extract have long been utilized in health supplements due to its high antioxidant content. Grape seed extract has been shown to enhance blood flow, protect against oxidative stress, and support healthy inflammation. It is also a main ingredient in USANA’s Proflavanol C health supplement. In Circulate+, the antioxidant properties combine with red spinach extract and L-arginine to support vasodilation, circulatory functions, and immunity.

Maintain Healthy Circulation with Circulate+

Supporting your circulatory system is fundamental to your overall health.  The ingredients in Circulate+ are designed to sustain nitric oxide production in the body, which supports vasodilation, circulatory functions, immunity, and overall cellular health. By maintaining better blood flow and reducing oxidative stress, Circulate+ helps your body function at its best.

Key Ingredients

  • Red spinach extract
  • L-arginine
  • Grape seed extract

See full list of ingredients

Usage

Add one (1) stick pack to 8–10 oz. water (or to taste), mix thoroughly, and enjoy.

Circulate+ Frequently Asked Questions

Red spinach extract (Amaranthus dubius) contains approximately twice the amount of dietary nitrate per kilogram of fresh weight compared to beetroot powder.

Circulate+ Test Strips FAQ

Nitric oxide test strips are a convenient, fast, and non-invasive way to estimate your body’s nitric oxide (NO) levels. They are useful for tracking cardiovascular health, the state of the oral microbiome, and certain aspects of diet and fitness.

The test strips measure nitrite levels in your saliva, which are a byproduct of dietary nitrates and a precursor to nitric oxide.

When the strip comes into contact with saliva, it reacts chemically and changes color. You can then compare the resulting color to a chart that is provided with the strips.

When foods rich in nitrates (beets, spinach, leafy greens) are consumed, the nitrates are converted to nitrites by oral bacteria. These nitrites are then converted to nitric oxide in the body which helps support healthy blood pressure, blood flow, and overall cardiovascular fitness.

The strips can be used as a tool to

  • Track the impact of nitrate-rich foods in the diet and their impact on the oral microbiome
  • Indicate oxygen availability to help optimize workouts
  • Provide early insights to potential health problems
  • Incentivize dietary and fitness improvements

Test at regular times for the most reliable tracking. You should avoid brushing your teeth, eating, or drinking anything except water for at least 30-60 minutes before testing. Use of antibacterial mouthwash will also disturb and negatively affect the oral microbiome needed to convert nitrates to nitrites.

If your nitric oxide test strip doesn’t change color, it may be an indication of something important. Possible reasons include:

  • Low Nitric Oxide levels: You may not be producing adequate nitric oxide due to a poor diet, chronic health conditions, or aging. A diet low in leafy greens, beets, and other nitrate-rich foods can lead to low nitrite levels in the saliva.
  • Genetics: Some individuals naturally have lower baseline levels of nitrate-converting enzymes due to genetics or underlying health conditions. Fortunately, you can train your body and oral microbiome to improve nitrate conversion through a healthy, nitrate-rich diet.
  • Oral Microbiome dysfunction: Use of antibacterial mouthwash or a recent dental cleaning can significantly diminish the oral bacteria needed to convert nitrates to nitrites. Therefore, even if your diet is sufficient, the color won’t change if you are lacking adequate nitrate converting bacteria.
  • Timing and Food Intake: Testing too soon after using a nitrate supplement or eating nitrate-rich foods may not give the body enough time to fully convert the nitrates into detectable nitrites. Eating, drinking, or brushing teeth within 30-60 minutes before testing can dilute or influence the saliva and alter the test.
  • Other factors: Excessive stress, certain medications, and a very sedentary lifestyle can also negatively impact nitric oxide production.

If your test strip still consistently shows no change in color, consult a healthcare provider for personalized guidance.

If you’re using USANA® Circulate+, remember that it’s formulated to support nitric oxide production through dual pathways—delivering nutrients that stimulate nitric oxide production both in the oral cavity and within blood vessels.

Pahlavani, N., Jafari, M., Sadeghi, O., Rezaei, M., Rasad, H., Rahdar, H. A., & Entezari, M. H. (2014). L-arginine supplementation and risk factors of cardiovascular diseases in healthy men: a double-blind randomized clinical trial. F1000Research, 3.

Melik, Z., Zaletel, P., Virtic, T., & Cankar, K. (2017). L-arginine as dietary supplement for improving microvascular function. Clinical hemorheology and microcirculation, 65(3), 205-217.

Maharaj, A., Fischer, S. M., Dillon, K. N., Kang, Y., Martinez, M. A., & Figueroa, A. (2022). Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women. Nutrients, 14(20), 4396.

Ochiai, M., Hayashi, T., Morita, M., Ina, K., Maeda, M., Watanabe, F., & Morishita, K. (2012). Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men. International journal of cardiology, 155(2), 257-261.

Wong, A., Alvarez-Alvarado, S., Jaime, S. J., Kinsey, A. W., Spicer, M. T., Madzima, T. A., & Figueroa, A. (2016). Combined whole-body vibration training and l-citrulline supplementation improves pressure wave reflection in obese postmenopausal women. Applied Physiology, Nutrition, and Metabolism, 41(3), 292-297.

Hwang, P., Morales Marroquín, F. E., Gann, J., Andre, T., McKinley-Barnard, S., Kim, C., … & Willoughby, D. S. (2018). Eight weeks of resistance training in conjunction with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained males. Journal of the International Society of Sports Nutrition, 15(1), 30.

Burgos, J., Viribay, A., Fernández-Lázaro, D., Calleja-González, J., González-Santos, J., & Mielgo-Ayuso, J. (2021). Combined Effects of Citrulline Plus Nitrate-Rich Beetroot Extract Co-Supplementation on Maximal and Endurance-Strength and Aerobic Power in Trained Male Triathletes: A Randomized Double-Blind, Placebo-Controlled Trial. Nutrients, 14(1), 40.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4525132/

https://academic.oup.com/femspd/article/51/3/443/631090

https://academic.oup.com/eurheartj/article-abstract/33/7/829/407043?redirectedFrom=fulltext

https://health.clevelandclinic.org/benefits-of-spinach

Amino acids are the building blocks of life. When linked together, they form proteins, which are fundamental components of all living organisms. To maintain your body’s health, you need the right amino acids to support protein synthesis.

There are 20 amino acids that the body uses to synthesize proteins, hormones, and neurotransmitters. While 11 amino acids are synthesized naturally in the body, nine amino acids must be obtained by other means. These are known as the nine essential amino acids. They include:

  • Leucine
  • Isoleucine
  • Valine
  • Phenylalanine
  • Threonine
  • Tryptophan
  • Methionine
  • Lysine
  • Histidine

These essential amino acids can be obtained through regular healthy diet. Complete protein sources such as meat, seafood, poultry, eggs, dairy products, and soy products can provide you with all nine essential amino acids. Even plant-based diets that include a variety of beans, nuts, seeds, whole grains, and vegetables can meet essential amino acid needs.

Unfortunately, many diets fall short of perfection and not everyone gets enough essential amino acids in their diet. Additionally, health conditions, fitness goals, aging, and other situations can create a need for supplemental essential amino acids to support protein health and overall wellness.

USANA Core Aminos drink mix contains all nine amino acids plus beta-hydroxy beta-methylbutyrate (HMB) to support muscle health and function, as well as energy production in healthy individuals. This supplement also supports overall health and wellness, including vitality and immune function.

Core Aminos for Healthy Aging

As humans age, factors such as hormonal changes, reduced physical activity, and nutritional deficiencies can lead to a decrease in muscle mass. While some muscle loss is normal with aging, excessive muscle loss, known as sarcopenia, can negatively affect daily living. This more progressive loss of muscle mass and strength affects 5-13% of people aged 60-70 years and increases to 11-50% for those aged 80 or above. Individuals struggling with sarcopenia may experience symptoms such as muscle weakness, poor balance leading to falls, reduced stamina, slower walking speed, and difficulty rising from a chair or climbing stairs.

To combat muscle loss, aging adults need a higher intake of essential amino acids, especially branched-chain amino acids (BCAAs), which are vital for maintaining muscle health and strength. However, diet restrictions and other challenges make it difficult for aging adults to maintain sufficient levels of amino acids.

Core Aminos offers a healthy solution for aging adults to obtain the necessary dose of essential amino acids. The powdered formula is easily digestible and absorbs more efficiently compared to whole foods or most protein powders. Incorporating Core Aminos into daily routine provides a practical way to support healthy aging. This simple drink mix helps aging adults maintain muscle mass, support overall health, and sustain quality of life.

Branched-Chain Amino Acids (BCAAs)

If you are an athlete or fitness enthusiast, you may be familiar with branched-chain amino acids (BCAAs). These particular amino acids are known for their potential benefits in reducing muscle soreness and improving recovery.

The three essential amino acids leucine, isoleucine, and valine are BCAAs. They get their label because their chemical structure includes a chain of carbon and hydrogen atoms that branches off the amino acid molecule. This chain gives them unique properties that support muscle health.

While the three BCAAs are all known for synthesis and muscle health, they each contribute differently to sustain muscle wellbeing.

Leucine is one of the most effective amino acids for supporting healthy muscle growth and recovery. It helps build protein by activating the mTOR (mammalian target of rapamycin) pathway. When mTOR is activated, it supports cell health and promotes production of proteins needed for muscle repair and growth, especially in response to exercise. This is why leucine is a key ingredient in Core Aminos.

Isoleucine plays a significant role in energy production by maintaining stable blood sugar levels and ensuring that muscles have sufficient glucose for energy, which is crucial for maintaining muscle function and preventing muscle breakdown.

Valine supports muscle metabolism by providing extra glucose for muscle tissues as an energy source during and after exercise. Valine also helps maintain nitrogen balance and supports muscle repair and growth.

Neurotransmitter Production and Brain Function

While proteins are generally associated with muscle growth, the thousands of proteins in the human body do everything from building muscle to brain function. Certain essential amino acids are direct precursors to neurotransmitters—the chemical messengers that transmit signals across synapses (the gaps between neurons) in the brain and nervous system. These essential amino acids play a role in maintaining cognitive functions such as memory, attention, learning, and mood.

Phenylalanine is a precursor to the non-essential amino acid tyrosine, which converts into the neurotransmitters dopamine, norepinephrine, and epinephrine—chemicals involved in mood regulation, stress response, and focus.

Histidine is an essential amino for infants and children but is considered semi-essential in most adults. The adult body can produce limited amounts of histidine; however, additional amounts of histidine are required to meet health needs. Histidine is a precursor to histamine, a neurotransmitter involved in regulating sleep-wake cycles, appetite, and cognitive functions. Histamine also plays a crucial role in immune response, particularly in allergic reactions and inflammations.

Tryptophan is a precursor to serotonin and melatonin, which regulate mood, sleep, and appetite. Eating tryptophan-rich foods or taking a supplement with tryptophan may help support mood regulation, relaxation, and sleep patterns in healthy individuals.

Unique Amino Acids

The final three essential amino acids have distinct characteristics and specialized functions that distinguish them from the other six. Like all essential amino acids, they are important to sustaining the health and wellbeing of the human physiology.

Threonine may help support immune system health, collagen, and elastin production for skin and connective tissues. It also helps in fat metabolism in the liver to maintain healthy fat accumulation.

Methionine contains sulfur, which is important for the body to synthesize the non-essential amino acid cysteine. Cysteine is a key component to glutathione, a powerful antioxidant that supports liver detoxification and fat metabolism.

Lysine is crucial for protein synthesis, collagen production, and immune function. Core Aminos contains lysine hydrochloride, a form of lysine combined with hydrochloric acid. Lysine hydrocholoride may help support immune function and muscle recovery in healthy individuals.

Beta-Hydroxy Beta-Methylbutyrate (HMB) Calcium Powder

The final notable ingredient in Core Aminos is Beta-hydroxy beta-methylbutyrate (HMB), a substance that may help support muscle and bone health. The body produces HMB naturally when breaking down the essential amino acid leucine. As a dietary supplement, HMB may support lean muscle growth, help support muscle health, and enhance exercise performance. It may also be beneficial for individuals looking to support muscle health from aging or muscle recovery after intense workouts.

Support Your Muscle Health with Core Aminos

Core Aminos can supplement your essential amino acids when your diet is not providing enough protein. The essential amino acids plus the HMB in this drink mix play an important role maintaining muscle health from supporting your physical goals to sustaining your brain function. While it is important to consume a balanced diet complete with a source of protein, Core Aminos’ unique formula ensures you receive additional essential amino acids to support the growth and repair of muscle tissue, promoting overall muscle wellness.

These statements have not been evaluated by the Food and Drug Administration.

Key Ingredients

  • L-Phenylalanine
  • L-Valine
  • L-Threonine
  • L-Tryptophan
  • L-Methionine
  • L-Leucine
  • L-Isoleucine
  • L-Lysine Hydrochloride
  • L-Histidine
  • HMB Calcium Powder

See full list of ingredients

Usage

Add one (1) scoop to 8 – 10 oz ounces of cold water, mix thoroughly, and enjoy.

Cruzat, V. F., Krause, M., & Newsholme, P. (2014). Amino acid supplementation and impact on immune function in the context of exercise. Journal of the international Society of Sports Nutrition, 11(1), 61.

Ruth, M. R., & Field, C. J. (2013). The immune modifying effects of amino acids on gut-associated lymphoid tissue. Journal of animal science and biotechnology, 4(1), 1-10.

Kim, D. H., Kim, S. H., Jeong, W. S., & Lee, H. Y. (2013). Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances. Journal of exercise nutrition & biochemistry, 17(4), 169.

Khemtong, C., Kuo, C. H., Chen, C. Y., Jaime, S. J., & Condello, G. (2021). Does branched-chain amino acids (BCAAs) supplementation attenuate muscle damage markers and soreness after resistance exercise in trained males? A meta-analysis of randomized controlled trials. Nutrients, 13(6), 1880.

Martinho, D. V., Nobari, H., Faria, A., Field, A., Duarte, D., & Sarmento, H. (2022). Oral branched-chain amino acids supplementation in athletes: A systematic review. Nutrients, 14(19), 4002.

Rose, A. J. (2019). Amino acid nutrition and metabolism in health and disease. Nutrients, 11(11), 2623.

Devignes, C. S., Carmeliet, G., & Stegen, S. (2022). Amino acid metabolism in skeletal cells. Bone Reports, 17, 101620.

Li, Q., & Hoppe, T. (2023). Role of amino acid metabolism in mitochondrial homeostasis. Frontiers in Cell and Developmental Biology, 11, 1127618.

Suzuki, H., Yamashiro, D., Ogawa, S., Kobayashi, M., Cho, D., Iizuka, A., … & Fujiwara, Y. (2020). Intake of seven essential amino acids improves cognitive function and psychological and social function in middle-aged and older adults: a double-blind, randomized, placebo-controlled trial. Frontiers in Nutrition, 7, 586166.

Marcon, M., & Zanella, P. B. (2022). The effect of branched-chain amino acids supplementation in physical exercise: A systematic review of human randomized controlled trials. Science & Sports, 37(5-6), 393-404.

Ispoglou, T., White, H., Preston, T., McElhone, S., McKenna, J., & Hind, K. (2016). Double-blind, placebo-controlled pilot trial of L-Leucine-enriched amino-acid mixtures on body composition and physical performance in men and women aged 65–75 years. European journal of clinical nutrition, 70(2), 182-188.

Fitzgerald, P. C. E., Manoliu, B., Herbillon, B., Steinert, R. E., Horowitz, M., & Feinle-Bisset, C. (2020). Effects of L-Phenylalanine on Energy Intake and Glycaemia-Impacts on Appetite Perceptions, Gastrointestinal Hormones and Gastric Emptying in Healthy Males. Nutrients, 12(6), 1788.

Ueda, K., Sanbongi, C., Yamaguchi, M., Ikegami, S., Hamaoka, T., & Fujita, S. (2017). The effects of phenylalanine on exercise-induced fat oxidation: a preliminary, double-blind, placebo-controlled, crossover trial. Journal of the International Society of Sports Nutrition, 14(1), 34.

Olsen, T., Øvrebø, B., Haj-Yasein, N., Lee, S., Svendsen, K., Hjorth, M., … & Vinknes, K. J. (2020). Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study. Journal of Translational Medicine, 18(1), 1-15.

Jenkins, T. A., Nguyen, J. C., Polglaze, K. E., & Bertrand, P. P. (2016). Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients, 8(1), 56.

Chojnacki, C., Gąsiorowska, A., Popławski, T., Konrad, P., Chojnacki, M., Fila, M., & Blasiak, J. (2023). Beneficial Effect of Increased Tryptophan Intake on Its Metabolism and Mental State of the Elderly. Nutrients, 15(4), 847.

https://my.clevelandclinic.org/health/diseases/23167-sarcopenia

https://pmc.ncbi.nlm.nih.gov/articles/PMC3060646/

https://examine.com/articles/mtor/

https://examine.com/conditions/sarcopenia/

USANA Proflavanol C100
 Proflavanol C200

Bioflavonoids and vitamin C unite to deliver powerful support for cardiovascular, immune, skin health, and more.*

A Blend of Powerful Antioxidants for One-of-a-Kind Health Support

A study published by the CDC cautioned that only one out of 10 adults in the eat enough fruits and vegetables. A healthy diet that includes the recommended intake can affect health from immune function to the cardiovascular system. Proflavanol C helps supplement this gap in diet with a broad variety of bioflavonoids combined with vitamin C to sustain healthy habits.*

Get a boost of bioflavonoid power with USANA Proflavanol C. This one-of-a-kind supplement is made with USANA Nutritional Hybrid Technology. So, you get a combination of potent antioxidants in one, two-layer tablet. Together, these nutrients will help you maintain good health in a number of ways:

  • Neutralizes free radicals that, over time, could cause excessive oxidative stress that damages cells*
  • Supports cardiovascular and circulatory health by helping to retain healthy, normal blood pressure and cholesterol levels, provided they are already in the normal range*
  • Helps maintain strong veins, blood vessels, and capillaries*
  • Supports balanced immune function*
  • Helps maintain joint, muscle, and skin health*

Proflavanol C100 delivers 100 mg of the highest quality grape-seed extract, plus a combination of green-tea extract, quercetin, hesperidin, and bilberry extract, and 300 mg of USANA’s unique Poly C vitamin C blend in one, two-layer tablet. Or, choose Proflavanol C200 to get twice the amount of flavonoids in one tablet.

When you add Proflavanol C to your daily routine, you won’t just feel good about the many health benefits. A tasty grape-flavored coating on each Proflavanol C tablet makes taking your supplements even more satisfying.*

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Extracting the Difference of USANA Proflavanol C

Before hitting the health benefits, let’s look a little closer at the active ingredients in Proflavanol C. First, flavonoids.

Bioflavonoids (also called flavonoids) are a diverse family of phytonutrients (nutrients from plants). They are responsible for the vibrant colors in fruits and vegetables.

Proflavanol C includes grape-seed extract, green-tea extract, quercetin, hesperidin, and bilberry extract. This combination includes a broad range of different types of bioflavonoids that help sustain overall health and well-being. Their antioxidant properties help support cardiovascular health, eye health, and more.

The flavonoids extracted from blue or purple berries like bilberries and grape seeds are called proanthocyanidins. They are also referred to as “OPCs” for oligomeric procyanidins or “PCOs” for procyanidolic oligomers.

OPCs are known to have limited absorption through the gut. That’s due to their high molecular weight and variable chemical structure. The bioavailability of the flavonoids in Proflavanol C has been enhanced in two ways:

  1. Using concentrated, smaller OPC molecules, which can be absorbed better than larger molecules found in many other extracts
  2. Delivering a consistent, uniquely balanced chemical composition verified to have at least 90 percent active OPCs

These premium flavonoids are combined with another ingredient that goes beyond what you might find in other supplements.

USANA’s Poly C combines ascorbic acid (a common form of vitamin C) with mineral salts. An in-house study found that this blend effectively raises levels of vitamin C in the body for a longer period of time than equal amounts of ascorbic acid alone. (Ascorbic acid is often the only form of vitamin C used in supplements.) The mineral forms of vitamin C are also thought to be friendlier to sensitive stomachs.*

These uniquely powerful ingredients work together for better effectiveness than you would get with either nutrient alone. They’re what make Proflavanol C an excellent choice for supporting your health.*

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Free Radicals Fear Proflavanol C

Many benefits of Proflavanol C stem from its incredible power as an antioxidant, thanks to its phytonutrient-dense ingredients:*

  • Flavonoids included in Proflavanol C have antioxidant activity that rivals, or even surpasses, vitamin C and E. Plus, these ingredients can support cell signaling associated with your body’s natural ability to generate antioxidants for even greater defense.*
  • Vitamin C has long been considered the “master antioxidant.” It actively neutralizes free radicals and helps regenerate other antioxidants, such as vitamin E.*

So, what’s the big deal about antioxidants, anyway?

Your body is naturally equipped to respond to the formation of free radicals generated through the activity of living. Everything from breathing to metabolizing your food can generate free radicals in your body.

Free radicals are highly reactive molecules that have an unpaired electron (an odd number of electrons). Nature really likes balance. So, that molecule will steal an electron from another molecule to regain stability. Generally, this process is a good thing. This activity prompts your body to initiate health-protecting responses. You need a certain amount of free radicals in your body to stay healthy.

But in today’s world, you’re bombarded with things that generate even more free radicals including:

  • Unhealthy foods
  • Stress
  • Pollution
  • Sedentary lifestyle
  • UV exposure
  • Smoking
  • Sleep deprivation

When there are more free radicals in your body than it can handle naturally, it can cause an imbalance in oxidative stress. And if that stress sticks around too long, it leads to oxidative damage.*

Over time, oxidative stress can begin a cascade of irreparable oxidative damage to your cells, DNA, proteins, and lipids. This damage can impact proper structure and function of almost every part of your body. Everything from respiratory function to brain and cardiovascular function can be impacted by chronic oxidative stress. It’s also thought to be a significant contributor to premature aging.*

Maintaining a balance between free radicals and antioxidants is necessary for proper physiological function to support good health. Antioxidants can give you a first line of defense in protecting cells against damaging oxidative stress.*

Working together in Proflavanol C, vitamin C and bioflavonoids provide powerful antioxidant protection to help you maintain good health.*

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Get Unbeatable Cardiovascular Support with Proflavanol C

If helping your cardiovascular system stay healthy is important to you, Proflavanol C should be at the heart of your supplement regimen. Most people don’t meet the standards for a healthy heart set by American Heart Association.*

Your cardiovascular system, also called your circulatory system, consists of your heart, lungs, and blood vessels—which include arteries, capillaries, and veins. This system is responsible for moving oxygen, nutrients, waste products, and other compounds through your body in your blood. Your heart is the muscular pump. The vessels are the “superhighway” through which your blood circulates.

Keeping this system flowing smoothly means maintaining the health of your blood vessels. Proflavanol C helps support vascular function. This will aid your efforts to maintain normal, healthy blood pressure levels—provided they are healthy to begin with.*

The cardiovascular advantages of Proflavanol C come from the unique combination of antioxidants.*

Proanthocyanidins from grapes are also present in red wine. They are believed to be one of the factors that contribute to the “French Paradox”—the fact that the French maintain good heart health despite a diet high in saturated fat. And vitamin C has been associated with markers of heart health, including supporting healthy blood flow.*

The combination of flavonoids and vitamin C in Proflavanol C helps maintain your cardiovascular health in a couple key ways.*

First, these nutrients help defend against low-density lipoprotein oxidation (bad cholesterol). This means Proflavanol C helps maintain lipids and proteins in cholesterol from changing into unhealthy end products.*

Proflavanol C also supports or maintains healthy circulation and blood flow by protecting endothelial cells from excessive oxidative stress. These cells line the interior surface of your blood vessels and arteries. One of their many functions is making nitric oxide. This substance signals for vasodilation (a fancy word for relaxing—or dilating—your blood vessels). That allows your blood to flow through your vascular system more easily.*

Nitric oxide function can be inhibited by excessive free radical damage. By protecting endothelial cells’ ability to produce nitric oxide, Proflavanol C supports healthy circulation.*

It even supports circulation in your tiniest blood vessels—including the peripheral arteries in your fingertips. A study conducted at Boston University School of Medicine found that combining grape-seed extract with vitamin C helped retain healthy micro-vascular function. Interestingly, this only occurred when epicatechin, another of the bioflavonoids in grape-seed extract, was also present in the blood.*

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The Collagen Connection: Heart, Skin, and More

Another key part of cardiovascular health is supporting the strength of your heart muscle and blood vessels. Both require collagen for structure and support. This means both require adequate amounts of vitamin C. (You also need other nutrients, like calcium and coenzyme Q10.) Because human bodies are incapable of manufacturing vitamin C, you must rely on your diet to satisfy daily requirements.*

Your body uses vitamin C to make many different types of collagen. These structural proteins are abundant throughout your body. Because they are needed to form healthy tissue.*

Here are a few of the most common types of collagen and where you’ll find them:

Type I: Fibers found in connective tissues of bone, teeth, tendons, and ligaments.
Type II: Found in cartilage.
Type III: Makes up connective tissues that give shape and strength to organs, such as the heart, liver, kidneys, etc.
Type IV: Found in the layers of cells in the blood vessels, muscles, and eye.

By supporting collagen production, Proflavanol C can help maintain a hardy heart, plus strong blood vessels, veins, and capillaries. But, as you can see, collagen is truly essential for an overall healthy body.*

Your appearance, too, can be affected by collagen. It’s integral to the skin’s elasticity and firmness. But collagen tends to start breaking down as you get older. So, taking vitamin C can help support production of this important protein.*

Your skin can also maintain health from within, with the help of the antioxidant activity provided by Proflavanol C. Defending against the oxidative effects of sun exposure may help protect against visible signs of aging. Of course, make sure to use smart sun safety measures to preserve your skin’s youthful appearance, too.*

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Help Your Body Produce Immune Cells with Proflavanol C

Your immune system is an incredibly complex protective mechanism designed to shield your body. And when your shield is weakened, your body is at risk. Exposure to potentially harmful microorganisms, along with stress or even intense exercise, can temporarily tax your immune system.

Bioflavonoids work with vitamin C to support two vital aspects of your natural immunity:

  1. Bioflavonoids can help support your cells’ ability to communicate with each other for healthy immune responses.*
  2. Vitamin C plays a role in the normal production and function of white blood cells and antibodies. You need to keep those abundant if you want a strong immune system.*

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Key Ingredients

  • Poly C
  • Grape-Seed Extract
  • Green-Tea Extract
  • Quercetin
  • Hesperidin
  • Bilberry Extract

See full list of ingredients
Proflavanol C

Usage

Adults, take two (2) to four (4) tablets daily, preferably with food.

Frequently Asked Questions About Proflavanol C

Proflavanol C100 and Proflavanol C200 both provide high-quality grape seed extract and vitamin C.

Each Proflavanol C100 tablet contains 100 mg of grape seed extract and 300 mg of vitamin C.
Each Proflavanol C200 tablet contains 200 mg of grape seed extract and 300 mg of vitamin C.

The coating of Proflavanol C is sweetened with stevia and natural grape flavor.

Ariga T. 2004. The antioxidative function, preventive action on disease and utilization of proanthocyanidins. Biofactors 21(1-4):197-201.

Bagchi D, et al. 2000. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148(2-3):187-97.

Bagchi D, et al. 1997. Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro. Res Commun Mol Pathol Pharmacol 95(2): 179-89.

Carr AC, Frei B. 1999. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr 69(6):1086-1107.

Cos P, et al. 2004. Proanthocyanidins in health care: current and new trends. Curr Med Chem 11(10):1345-59.

da Silva Porto PA, Laranjinha JA, de Freitas VA. 2003. Antioxidant protection of low density lipoprotein by procyanidins: structure/activity relationships. Biochem Pharmacol 66(6):947-54.

Meyer AS, et al. 1997. Inhibition of Human Low-Density Lipoprotein Oxidation in Relation to Composition of Phenolic Antioxidants in Grapes. J Agric Food Chem 45:1638-1643.

Murad S, et al. 1981. Regulation of collagen synthesis by ascorbic acid. Proc Natl Acad Sci 78(5):2879-82.

Natella F, et al. 2002. Grape Seed Proanthocyanidins Prevent Plasma Postprandial Oxidative Stress in Humans. J Agric Food Chem 50(26):7720-5.

Nuttall SL, Kendall MJ, Bombardelli E, Morazzoni P. 1998. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther 23(5):385-9.

Osganian SK, Stampfer MJ, Rimm E, et al. 2003 Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol 42(2):246-252.

Rabovsky A, Cuomo J. 2000. Pharmacokinetics of Poly C versus Ascorbic Acid. USANA Clinical Research Bulletin.

Yoshida M, et al. 2007. Prospective study showing that dietary vitamin C reduced the risk of age-related cataracts in a middle-aged Japanese population. Eur J Nutr 46(2):118-124.

Ngamukote S, et al. 2011. Cholesterol-lowering activity of the major polyphenols in grape seed. Molecules 16: 5054-5061.

Sapwarobol S, et al. 2012. Postprandial blood glucose response to grape seed extract in healthy participants: A pilot study. Pharmacogn Mag 8(31): 192-196.

Figueroa-Méndez R, Rivas-Arancibia S. 2015. Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain. Front Physiol 6: 397.

Cires MJ, Wong X, Carrasco-Pozo C, Gotteland M. 2017. The Gastrointestinal Tract as a Key Target Organ for the Health-Promoting Effects of Dietary Proanthocyanidins. Front Nutr [Internet] [accessed 13 April 2018] Available at https://www.frontiersin.org/articles/10.3389/fnut.2016.00057/full

Chen S, et al. 2015. Grape Seed Proanthocyanidin Extract Ameliorates Diabetic Bladder Dysfunction via the Activation of the Nrf2 Pathway. PLoS One 10(5) [Internet] [accessed 18 April 2018] Available at https://www.ncbi.nlm.nih.gov/pubmed/25974036

Lobo V, Patil A, Phatak A, Chandra N. 2010. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev 4(8): 118-126.

Segiev PV, Dontsova OA, Berezkin GV. 2015. Theories of aging: an ever-evolving field. 7(1): 9-18.

Padayatty S, Levine M. 2008. Fruit and vegetables: think variety, go ahead, eat! Am Jour Clin Nutr 87(1): 5-7.

May J, Harrison F. 2013. Role of vitamin C in the function of the vascular endothelium. Antioxid Redox Signal 19(17): 2068-2083.

Pandey K, Rizvi S. 2009. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2(5): 270-278.

Fujii H, et al. 2006. Protective effect of grape seed polyphenols against high glucose-induced oxidative stress. Biosci, Biotech, Biochem 70(9): 2104-2011.

Juraschek SP, Miller ER 3rd, Gelber AC. 2011. Effect of oral vitamin C supplementation on serum uric acid: a meta-analysis of randomized controlled trials. Arthritis Care Res (Hoboken) 63(9): 1295-306.

English J, Cass H. 2013. The Collagen Connection. Nutrition Review [Internet] [accessed 17 April 2018] Available at https://nutritionreview.org/2013/04/collagen-connection/

Cosgrove M, et al. 2007. Dietary nutrient intakes and skin-aging appearance among middle-aged American women. Am Jour Clin Nutr 86(4): 1225-1231.

Other resources

https://nccih.nih.gov/health/grapeseed/ataglance.htm

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Build Your Foundation for Health with USANA CellSentials

Look and feel your best every day with the essential nutrients you need for cellular health in USANA® Vita Antioxidant and Core Minerals.

Nourish, protect, and renew the health of your cells so you can be at your best every day with the USANA CellSentials. This cellular nutrition system includes two advanced nutritional supplements: Core Minerals and Vita Antioxidant. Together, they deliver a broad spectrum of vitamins, minerals, antioxidants, and additional nutrients for comprehensive support for your long-term health.*

The CellSentials are so much more than your average multivitamin. Each daily dose provides essential vitamins, minerals, antioxidants, plus additional key nutrients. The exclusive InCelligence Complex, made using USANA’s patented USANA InCelligence Technology®, goes beyond nourishing the body. It also helps activate your body’s natural ability to respond to stress and keep your cells healthy.*

The CellSentials are formulated to meet the needs of generally healthy adults of any age who eat a balanced diet. They offer excellent nutritional support for the entire body:*

The combination of Vita Antioxidant and Core Minerals delivers results you can feel. After one month of taking the CellSentials, an in-house USANA study found that participants self-reported perceived benefits in their mental and physical health, as well as vitality.*

Each tablet has readily bioavailable forms of each nutrient. This is important because your body can’t use what it can’t absorb.

And every USANA product is made to the highest standards. So, you can trust the CellSentials will have excellent completeness, potency, purity, and safety. For easy swallowing, the Core Minerals and Vita Antioxidant tablets have a sunflower-based coating.

Support your overall health with the CellSentials—a strong nutritional foundation you can build on.*

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Your Best Health Starts with a Better Supplement

Vibrant health starts with well-nourished cells. And there’s a reason an estimated eight out of 10 people take supplements: it’s not always easy to eat right. Statistics continue to show that most people need to supplement. Their daily diet simply doesn’t supply even the minimum recommended amounts of many vitamins and minerals. And even if you could design a nutritionally perfect set of meals and snacks, would you eat that same food every day?

Like a nutritional “insurance plan,” a good daily supplement can help fill in the gaps. So, the question becomes, what is a good daily supplement?

Take a trip down the aisles of your local market. The choices for daily supplements can be daunting. You could choose a gummy that’s tasty (and probably laced with sugar) or a one-a-day multi. Either choice might provide enough of a basic set of micronutrients to avoid a deficiency. But you likely won’t get the range or levels of nutrients you need to achieve optimal health.

You see, there’s a difference.

Nutritional authorities often establish the recommended nutrient levels on supplement labels based on what it takes to avoid deficiency. (This is referenced as %DV—Percent of Daily Value—on labels in the United States.) The amounts aren’t at levels research shows can help make a difference in your long-term health.

To illustrate the differences, here’s a couple examples:

  • The Food and Nutrition Board of the Institutes of Medicine set a Recommended Dietary Allowance (RDA) for vitamin D of 600 IU/day or 15 mcg. However, research has shown you often need higher levels to achieve the blood levels needed for good health. In fact, a 2011 in-house study conducted at USANA found that supplementation of up to 5,000 IU was necessary to reach optimal levels (40-60ng/mL). (Labels in the United States now list vitamin D amounts in micrograms. 5000 IU equates to about 125 mcg per day.)
  • The current RDA for vitamin B12 is 2.4 mcg/day. However, some research has shown that up to 500 mcg had positive effects on homocysteine levels in the body—when combined with .5-5 mg of folic acid. Homocysteine is an amino acid that is measured as a marker of heart health.

That’s not all. Another consideration in your supplement selection is the ratio of nutrients used together. It can be tempting to pick and choose your nutrients. But those nutrients might be affected by others. For instance, iron and copper work better together. You need enough of one for the other to be used correctly in the body. Calcium, too, requires adequate levels of magnesium, vitamin K, and vitamin D to maintain healthy bones. The relationships between nutrients can be complex.

A well-designed multivitamin and mineral supplement is made with an understanding of the complexities. It provides you with the right amounts and the right balance of nutrients. And those nutrients are delivered in forms that can be used by the body. That’s where the USANA CellSentials come in.

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The USANA CellSentials are Made with Smart Supplement Design

Vita Antioxidant and Core Minerals support good health with a broad range of premium-quality micronutrients. When taken together, you get a carefully formulated balance of four key types of nutrients to nourish, protect, and renew your cells:

  1. Essential vitamins, minerals, and trace minerals that nourish cellular health*
  2. Other beneficial building blocks and substances (often called cofactors) your body needs to use vitamins and minerals effectively*
  3. Dietary phytonutrients and antioxidants to defend against oxidative stress*
  4. Targeted nutrients that can act like cell signaling molecules to help promote the body’s natural health protection and renewal reactions*

Adding the CellSentials to a varied diet will help ensure you consume the right amounts of key nutrients. You will have a great foundation to help support vibrant health every day. When taken for one month, the CellSentials have been shown to increase circulating blood levels of many nutrients known to be beneficial for health.*

The CellSentials go beyond simply supporting good health with nutrients. They also help activate some of your cells’ responses that can keep you healthy with InCelligence Technology. These responses promote youthful cellular function, so your body can adapt to your unique lifestyle needs and help you age well.*

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Nourish Your Cellular Health with Optimal Amounts of Essential Nutrients

Your cells need the right ingredients to maintain health. That includes the nutrients needed to help them (and you) thrive. Support the health and longevity of your cells with an essential foundation of optimal nourishment. Core Minerals and Vita Antioxidant are designed to work together to support whole body health.*

Core Minerals

Core Minerals is a premium blend of highly absorbable minerals, trace minerals, and vitamin C.

Minerals are essential elements for health and well-being. Your body couldn’t function without them. They play a role in all physiological processes and help balance and regulate your body chemistry.*

Magnesium

Core Minerals is an excellent source of magnesium. This essential mineral helps more than 300 enzyme systems work properly. Magnesium is critical for helping the body use calcium and vitamin D so your body can make strong bones. It also supports energy production, as well as nerve, muscle, and cardiovascular function.*

Iodine

Core Minerals contains high-potency iodine. The mineral is crucial for the normal production of thyroid hormones. These hormones help regulate metabolism, growth, reproduction, and protein synthesis. Supplemental iodine is especially important if you are on a vegetarian diet, avoiding seafood, or restricting your iodized-salt intake.*

Selenium

The formula’s high-potency selenium aids your body’s natural ability to renew glutathione, an antioxidant made in your body. Selenium is important in thyroid hormone metabolism and immune function. Studies have also shown its helps maintain prostate health.*

Manganese

Core Minerals is a good source of manganese. Don’t confused this essential mineral with magnesium. Manganese plays different roles. It’s important for protein and glucose metabolism. It supports normal brain function. And, it helps maintain healthy connective tissues, bones, arteries, and other organs.*

Molybdenum

Core Minerals is an excellent source of molybdenum. This trace mineral is a cofactor for a number of enzymes and is necessary for the metabolism of sulfur-containing amino acids. It also supports protein metabolism and strong teeth.*

Copper

Core Minerals is rich in copper, which is critical for superoxide dismutase (SOD)—an antioxidant enzyme. It helps form hemoglobin and collagen. So, it also plays a role in connective tissue formation and healthy skin.*

Calcium

Calcium is the most abundant mineral in the body. You need it for healthy bones, teeth, muscle, and nerve function. Having enough calcium isn’t the problem for most people. It’s properly using what you have. So it’s important to also get enough vitamin K and magnesium. If you don’t eat much dairy or calcium-rich foods, you may want to consider adding MagneCal D to your daily routine to meet your daily needs. *

Zinc

Core Minerals is high in zinc, an antioxidant that is vital to overall health. Zinc is involved in many processes, including metabolism, immune function, vision, and skin health.*

Chromium

The high-potency chromium polynicotinate in Core Minerals is an important component of the Glucose Tolerance Factor (GTF). This helps maintain healthy glucose metabolism already in the normal range.*

Boron

Boron supports the body’s ability to use calcium, magnesium, and phosphorus. That makes it necessary for strong bones. It also plays a role in healthy brain function.*

Vanadium

Vanadium helps support healthy serum glucose levels, provided they are already healthy.*

Silicon

Maintaining a good balance of silicon in the body is important for supporting strong bones and connective tissues.*

N-Acetyl L-Cysteine

N-Acetyl L-Cysteine helps support your body’s production of compounds like glutathione—an antioxidant that plays a role in liver health and detoxification.*

Ultra-Trace Minerals

The blend used in Core Minerals contains many naturally occurring ionic trace minerals. They are sourced from inland sea salt, and 99 percent of the sodium is removed. Ionic trace minerals are mineral molecules that have bonded with water so they can be absorbed. They help conduct electrical signals throughout the body.*

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Vita Antioxidant

A full range of vitamins is essential to your whole-body well-being. Vita Antioxidant supplies carefully balanced levels of high-quality vitamins and antioxidants, plus the InCelligence Complex.* Some scientific evidence suggests that consumption of antioxidant vitamins may reduce the risk of certain forms of cancer. However, the FDA has determined that this evidence is limited and not conclusive.

Vitamin A

High-potency vitamin A in Vita Antioxidant comes from three sources: retinyl acetate, mixed carotenoids, and beta-carotene. Retinyl acetate is preformed vitamin A for those whose bodies don’t efficiently convert beta carotene to vitamin A. The plant-derived mixed carotenoids include alpha-carotene, gamma-carotene, lycopene, beta-carotene, and more. Beta-carotene is the provitamin form of vitamin A. That means it converts to vitamin A in the body only as needed. It helps maintain a strong heart, immune function, and eye and lung health. The carotenoid antioxidants help maintain skin and eye health by providing oxidative defense against damaging sources of free radicals from the environment.*

B Vitamins

Vita Antioxidant is an excellent source of vitamins B6 and B12, thiamin, riboflavin, niacin, biotin, pantothenic acid, and folate. The B vitamins are essential to many aspects of your health. You need them for energy and metabolism; immune function; and healthy hair, skin, and nails.*

Maintaining your cardiovascular health also requires B vitamins. They help maintain already healthy homocysteine levels.* And, as part of a well-balanced diet—that’s low in saturated fat and cholesterol—folate, vitamin B6, and vitamin B12 may reduce the risk of vascular disease. The FDA evaluated the above claim and found that while it is known that diets low in saturated fat and cholesterol reduce the risk of heart disease and other vascular diseases, the evidence in support of the above claim is inconclusive.

B vitamins also support normal brain and nerve function. Folate is especially important for women of childbearing age to help support healthy fetal brain and nerve development.*

Inositol, which is sometimes referred to as vitamin B8, is a sugar alcohol that has B-vitamin-like activity to support healthy cellular function and communication.*

Vitamin D

Your daily dose of sunshine! Support your whole-body health with the high-potency vitamin D in Vita Antioxidant. Many people don’t get enough vitamin D, even those in sunny climates. And this important nutrient continues to show benefits for many aspects of health. It supports calcium absorption for healthy bone density. It also supports healthy cell growth as well as muscle, cardiovascular, and immune function. Vita Antioxidant uses vitamin D3. Research suggests it is better at raising levels of vitamin D in the blood.*

Vitamin E and Mixed Tocopherols

Vita Antioxidant is a good source of vitamin E. It also contains 20 mg of mixed D-gamma, D-delta, and D-beta tocopherols in each tablet. The mixed tocopherols, though not technically vitamin E, offer similar functions. Antioxidants, like vitamin E, help defend your cells against the oxidative stress caused by sunlight, pollution, and stress. All of these can prematurely age your skin. When combined with zinc, beta-carotene, and vitamin C, as in the CellSentials, vitamin E also helps maintain long-term eye health.*

Vitamin C

Vita Antioxidant is rich in vitamin C. USANA uses a unique Poly C® vitamin C blend, which provides higher levels of vitamin C in plasma than ascorbic acid alone.*

Vitamin C is essential for making collagen—proteins that provide elasticity to your connective tissues. That’s why vitamin C is helpful in maintaining healthy veins and arteries, muscles, cartilage, tendons, bones, teeth, and skin. It also supports fat and protein metabolism, as well as the healthy production of immune cells.*

Note: You will notice 300 mg of vitamin C on the Core Minerals label. This is because the magnesium and calcium blends are made partly from the ascorbate forms of the nutrients. Ascorbate is a source of vitamin C.

Vitamin K

Vita Antioxidant is high in vitamin K1 and K2 for maximum effectiveness, as both forms have been shown to be beneficial for bone mineral density. This essential nutrient also has shown benefits for blood clotting and vascular health. Vitamin K is absorbed quickly, but also disappears from circulation in about six hours. So, regular dietary intake of vitamin K throughout the day is important for maintaining adequate amounts in the body. *

Lutein

See a healthy future for your eyes with lutein. This yellow-pigmented carotenoid is concentrated in the eye’s macula. It acts as a filter for blue light to aid clear vision. Lutein also helps support healthy skin.*

Lycopene

Get an added boost of heart and skin health support with lycopene. It’s one of the six major carotenoids found in your blood. But, your body can’t make lycopene. It must come from your diet. The red-pigmented nutrient is most often found in red fruits and vegetables. It offers great antioxidant activity and also supports intracellular communication.*

Choline

Choline is usually grouped with the B vitamins, even though it is not technically a vitamin. Regardless of classification, this key nutrient supports cell structure. It aids in the transmission of nerve impulses from the brain throughout the central nervous system. Choline also supports liver function and helps maintain healthy homocysteine levels.*

Coenzyme Q10

To keep you and your cells full of energy, Vita Antioxidant also includes coenzyme q10. This compound is key to producing the energy needed to power all of your cells. It also acts as an antioxidant to protect against damaging oxidative stress generated during the production of cellular energy.*

If you would like to supplement with more coenzyme q10, consider trying USANA® CoQuinone.

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Build Cellular Resilience and Longevity with the InCelligence Complex

Healthy dad with son and daughter outdoors

Your lifestyle is unique. Your diet, activity levels, environment, sleep patterns, and stress levels all bring unique challenges to the health and integrity of your cells. You can help your cells adapt to those unique needs. Start with the healthy foundation of nutrition your cells need to function in the CellSentials. Then help build cellular resilience with the InCelligence Complex.*

The InCelligence Complex in Vita Antioxidant is a powerful blend of ingredients that supports a network of cell-signaling pathways. These pathways help cells adapt and respond to whatever life throws at them.*

Alpha Lipoic Acid

Alpha lipoic acid (ALA) is one of the most powerful antioxidants. Because it’s only found in very small amounts in certain foods, ALA is especially good to take in supplement form. It offers several benefits for health, including aiding detoxification. ALA is fat and water soluble, so it offers excellent absorption and works in all tissues of the body.*

Green Tea Extract

Green tea has a long history of use in traditional medicine. It is made from unfermented leaves and is thought to have the highest concentration of polyphenols. The most studied catechin (a type of antioxidant) in green tea is epigallocatechin gallate (EGCG). It is well-known for supporting many aspects of well-being, including heart, liver, and metabolic health. The green tea extract used in the InCelligence Complex is decaffeinated.*

Resveratrol

This key component of red wine is another source of phenolic compounds. Resveratrol has been shown to offer benefits for bones, brain, skin, and the cardiovascular system. It also helps maintain healthy blood glucose levels already in the normal range. The InCelligence Complex includes a premium quality, naturally fermented resveratrol for exceptional purity.*

 Olivol® Olive-Fruit Extract

Olives and olive oil have long been known as one of the secrets of the Mediterranean-style diet. USANA’s Olivol delivers an exceptionally pure, concentrated dose of the phenolic compounds (a type of antioxidants) in olives, including tyrosol and hydroxytyrosol.*

Quercetin

Quercetin is one of the most abundant flavonoids found in fruits and vegetables (grapes, onions). It offers a number of benefits for maintaining health, including powerful antioxidant activity. Quercetin also helps other natural compounds, like resveratrol, boost their effectiveness. The InCelligence Complex includes quercetin dihydrate—a concentrated form.*

Rutin & Hesperidin

Rutin and hesperidin are citrus bioflavonoids. They’re known to complement the activity of quercetin to offer a number of beneficial biological activities.*

Meriva® †Bioavailable Curcumin

Curcumin, which comes from the spice turmeric, has been used in traditional cultures for centuries. Research continues to reveal ways that curcumin supports good health. This includes benefits for joints, blood vessels, and eyes. Curcumin typically is not absorbed well in the body. However, the InCelligence Complex includes a phytosome delivery form in which the curcumin is bound with fat, so it can cross cellular membranes more easily. This novel delivery form has been shown to improve bioavailability nearly 30-fold.*

PQQ (pyrroloquinoline quinone)

PQQ is an excellent antioxidant. It is particularly effective at helping protect mitochondria from free radical damage and stimulate the production of new mitochondria. PQQ is so effective because it is very efficient at transferring electrons. This ability to readily transfer electrons helps activated PQQ scavenge and neutralize free radicals and then be quickly recycled back into their active form. PQQ works synergistically with N-Acetyl L-Cysteine (NAC) and the InCelligence complex to stay recharged. NAC helps the body produce glutathione, which is the primary molecule responsible for keeping PQQ recharged and ready for action.

USANA InCelligence Technology® Joins Cellular Conversations

It’s time for a new approach to product design. InCelligence Technology plays an important role in helping enhance your body’s natural ability to help protect itself from stress and renew youthful, normal cellular function. This patented technology uses select nutrients to not only support but also stimulate specific cellular processes. It triggers these processes by targeting cell signaling pathways—your cells’ network for sending and receiving communications. InCelligence is an innovative way to help your body create vibrant health.*

The InCelligence Complex supports a broad range of pathways and processes for whole-body health. Two of the most important in the CellSentials are:

  • The production of endogenous antioxidants—those created in cells—for powerful protection
  • The activation of mitophagy—a cellular cleanup process—to help renew efficient production of the energy that powers your cells*

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Protect Your Cellular Health with Powerful Antioxidant Defense

Illustration of InCelligence antioxidant activity

The CellSentials deliver a number of dietary antioxidants to provide a first layer of defense against cell-damaging free radicals. But your body is made of trillions of cells that need protection. So, dietary antioxidants (also known as exogenous antioxidants) may not be enough.*

What if you could help your cells protect themselves?*

Your cells are naturally equipped with powerful antioxidants. Molecules such as superoxide dismutase, catalase, and glutathione are made in your cells. The nutrients in the InCelligence Complex help proactively stimulate production of these natural protectors.*

It’s simple math. Dietary antioxidant molecules neutralize free radicals in a one-to-one or one-to-two ratio: one dietary antioxidant eliminates one or two free-radical molecule(s). Endogenous antioxidants are typically able to neutralize 100 or more free-radical molecules during their lifespans. By encouraging the production of your natural antioxidants, the InCelligence Complex helps deliver significantly more protection. It is a powerful way to defend against an imbalance of the oxidative stress that can damage your healthy cells.*

Your cells innately know how to protect themselves from damaging free radicals. A key controller of this cellular defense mechanism is the Nrf2 (nuclear factor erythroid 2–related factor 2)-antioxidant response element (ARE) pathway. When a cell senses an oxidant, also known as a free radical, it activates Nrf2. This begins a complex cascade of events that ultimately results in antioxidants being released by the cell. Certain chemicals, including those found in the InCelligence Complex, support stimulation of the Nrf2-ARE pathway to proactively promote antioxidant production.*

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Renew Your Health by Supporting Youthful Cellular Function

Your cells produce energy (ATP—adenosine triphosphate) in the mitochondria. This cellular energy production also generates a lot of free radicals. Natural antioxidants in the cell neutralize many of the free radicals. But some mitochondria will still be damaged over time. Damaged mitochondria can work inefficiently, producing less ATP and more damaging free radicals. This causes a self-perpetuating cycle of damage.*

The cell maintains efficiency through a natural response called mitophagy. Think of it like taking out the trash. Or cellular quality control. Initiating mitophagy degrades, removes, or recycles the damaged mitochondria. So, they aren’t causing damaging reactions and the cell stays healthy. However, age or other lifestyle factors may slow this process. The InCelligence Complex helps activate mitophagy to renew efficient energy production and keep cells acting youthful.*

A cell works just like an engine—it works better when it’s clean than when it’s dirty. The mammalian target of rapamycin (mTOR) signaling pathway is a key regulator of cell metabolism, growth, and survival. It controls autophagy—a cleanup process that gathers and breaks down proteins in the cell.

Mitophagy is a type of autophagy specific to mitochondria. When the cell has limited availability of nutrients, as in the case of caloric restriction, mTOR initiates mitophagy. After proteins are degraded, the mitochondria can use those proteins to help fuel the process needed to create ATP—cellular energy.

When nutrients are abundant (i.e., when you’re eating regularly), mTOR reduces autophagy because the cells have plenty of fuel. So, they don’t need to be as efficient. The compounds found in the InCelligence Complex can cause cellular responses that mimic those caused by caloric restriction. This can start the cellular housekeeping process that helps keep your cells efficient, but you don’t have to eat less.*

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Key Ingredients

  • Vitamin A
  • Vitamin D
  • B Vitamins
  • Magnesium
  • Iodine
  • N-Acetyl L-Cysteine
  • InCelligence Complex

See full list of ingredients:

Core Minerals

Vita Antioxidant

Usage

Adults take two (2) tablets of Core Minerals and two (2) tablets of Vita Antioxidant twice daily, preferably with food.

Ideal For

  • All generally healthy adults over age 18
  • Certified Kosher (U.S. formula)

Frequently Asked Questions About USANA CellSentials

It is simply not possible to condense the nutrient amounts in the CellSentials into fewer tablets. For example, if USANA provided the full CellSentials dosage in one pill, the tablet would be so large it would be like swallowing a golf ball.  If nutrient amounts in the CellSentials were reduced to levels appropriate for a single tablet dose, nutrient amounts would have to mimic Centrum® or One-A-Day®, with minimal antioxidants, strictly RDA levels of vitamins, and very little in the way of minerals. Higher nutrient amounts require space, and unfortunately there are limits to what can be condensed into a single tablet.

USANA’s CellSentials do not contain iron. The widespread availability of iron-fortified foods ensure that most adults receive sufficient iron from their diets (as a common example, just one cup of a popular toasted oat cereal provides 45% of the RDA for iron).

Iron supplementation is best handled separately by those who specifically need it. One such group includes pregnant women, who can get the benefits of the CellSentials plus iron in the Prenatal CellSentials.

During the premarketing evaluation of the CellSentials, and the Sanoviv Medical Institute trial participants were asked to report any unexpected reaction both positive and negative as a consequence of consuming the Cellsentials. The lack of any significant adverse events demonstrates that the new Cellsentials are generally safe and well-tolerated in healthy people. If you have a medical condition or if you are taking prescription medications we strongly suggest that you consult with your healthcare provider and pharmacist to determine if the CellSentials are appropriate for you to take.

Hypercarotenemia is a benign temporary yellowing of the skin caused by consuming large amounts of beta-carotene. The amount necessary to cause this type of condition, regardless of the weight of the individual, far exceeds the amount contained in the daily dose of the CellSentials. The amount of beta-carotene in a daily dose of the Vita Antioxidant is similar to the amount of beta-carotene obtained from one small carrot. Eating one carrot per day won’t cause hypercarotenemia.

If, however, someone is regularly juicing vegetables or consuming large quantities of vegetables high in beta-carotene (in addition to taking the CellSentials), it may be possible to develop hypercarotenemia.

Age-Related Eye Disease Study Research Group. A randomized, placebo controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. 2001. Arch Ophthalmol 119(10): 1417-36.

Barringer TA, Kirk JK, Santaniello AC, Foley KL, Michielutte R. Effect of a multivitamin and mineral supplement on infection and quality of life. A randomized, double-blind, placebo-controlled trial. 2003. Ann Intern Med 138(5):365-71.

Cosgrove MC, Franco OH, Granger SP, Murray PG, Mayes AE. Dietary nutrient intakes and skin-aging appearance among middle-aged American women. 2007. AJCN 86(4):1224-31.

Girodon F, Galan P, Monget AL, Boutron-Ruault MC, Brunet-Lecomte P, Preziosi P, Arnaud J, Manuguerra JC, Herchberg S. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial. 1999. Arch Intern Med 159(7):748-54.

Heinrich U, Gartner C, Wiebusch M, Eichler O, Sies H, Tronnier H, Stahl W. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. 2003. J Nutr 133(1):98-101.

Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. 2004. Am J Clin Nutr 79(3):362-371.

Kaikkonen J, Tuomainen TP, Nyyssonen K, Salonen JT. Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. 2002. Free Radic Res 36(4):389-97.

Lutsenko EA, Carcamo JM, Golde DW. Vitamin C Prevents DNA Mutation Induced by Oxidative Stress. 2002. J Biol Chem 277(19):16895-9.

Merchant AT, Hu FB, Spiegelman D, Willett WC, Rimm EB, Ascherio A. The use of B vitamin supplements and peripheral arterial disease risk in men are inversely related. 2003. J Nutr 133(9):2863-7.

Meydani SN, Meydani M, Blumberg JB, Leka LS, Siber G, Loszewski R, Thompson C, Pedrosa MC, Diamond RD, Stollar BD. Vitamin E supplementation and in vivo immune response in healthy elderly subjects: a randomized controlled trial. 1997. JAMA 277(17):1380-6.

Placzek M, Gaube S, Kerkmann U, Gilbertz KP, Herzinger T, Haen E, Przybilla B. Ultraviolet B-induced DNA damage in human epidermis is modifed by the antioxidants ascorbic acid and D-alpha-tocopherol. 2005. J Invest Dermatol 124(2):304-7.

AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. 2004. Curr Med Chem 11(9):1135-46.

Sreejayan, Rao MN. Curcuminoids as potent inhibitors of lipid peroxidation. 1994. J Pharm Pharmacol. 46(12):1013-6.

Beekmann, K. (2015). The effect of quercetin and kaempferol aglycones and glucuronides on peroxisome proliferator-activated receptor-gamma (PPAR-gamma). Food and Function. Volume 6 (4); 1098-1107.

Elavarasan J. (2012). Hesperidin-mediated expression of Nrf2 and upregulation of antioxidant status in senescent rat heart. Journal of Pharmacy and Pharmacology. Volume 64 (10); 1472-1482.

Gonzalez-Polo, R.A. (2015). Is the modulation of autophagy the future in the treatment of neurodegenerative diseases?. Current Topics in Medicinal Chemistry. Volume 15 (21); 2152-2174.

Moreira, P.I. (2007). Lipoic acid in N-acetyl cysteine decrease mitochondrial-related oxidative stress… Journal of Alzh Dis. Volume 12 (2); 195-206.

Suliman H.B. (2016) Mitochondrial quality control as a therapeutic target. Pharmacological Reviews. Volume 68 (1); 20-48.

Wang, K.C. (2013). Alpha-lipoic acid endogenous peroxisomeproliferator-activated receptor-gamma ameliorate experimental autoimmune encephalomyelitis in mice. Clinical Science. Volume 125 (7); 329-34.

Why Trace Minerals? Trace Minerals Research [Internet] [accessed 12 Feb 18] Available at https://traceminerals.com/why-trace-minerals/

Watts D. Nutrient Interrelationships: Minerals — Vitamins — Endocrines. Orthomolecular.org [Internet] [accessed 12 Feb 18] Available at http://www.orthomolecular.org/library/jom/1990/pdf/1990-v05n01-p011.pdf

1998. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists’ Collaboration. BMJ 316(7135):894-898. 

Hoffmann P, Berry M. 2008. The influence of selenium on immune responses. Mol Nutr Food Res 52(11): 1273-1280.

Deepmala, et al. 2015. Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review. Neurosci Biobehav Rev 55: 294-321.

Liu W, Liou S, Hong T, Liu I. 2017. Protective Effects of Hesperidin (Citrus Flavonone) on High Glucose Induced Oxidative Stress and Apoptosis in a Cellular Model… Nutrients 9(12).

Martínez-Huélamo M, Rodríguez-Morató J, Boronat A, de la Torre R. 2017. Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection. Antioxidants 6(4):73.

Testa G, Biasi F, Poli G, Chiarpotto E. 2014. Calorie restriction and dietary restriction mimetics: a strategy for improving healthy aging and longevity. Curr Pharm Des 20(18): 2950-77.

Kim H, Quon M, Kim J. 2014. New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biology 2: 187-195.

Appendino G, et al. 2011. Potential role of curcumin phytosome (Meriva) in controlling… Panminerva Med 53(3 Suppl 1): 43-9.

Pizzino G, et al. 2017. Oxidative stress: harms and benefits for human health. Oxid Med Cell Long [Internet] [accessed 5 Mar 18] Available at https://www.hindawi.com/journals/omcl/2017/8416763/

Nguyen T, Nioi P, Pickett C. 2009. The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress. J Biol Chem 284(20): 13291-13295.

Ma Q. 2013. Role of Nrf2 in Oxidative Stress and Toxicity. Annu Rev Pharmacol Toxicol 53: 401-426.

Laplante M, Sabatini D. 2009. mTOR signaling at a glance. Journal of Cell Science 122: 3589-3594.

Wei Y, Zhang Y, Cai Y, Xu M. 2014. The role of mitochondria in mTOR-regulated longevity. Bio Rev 90(1): 167-181.

Other Resources

National Institutes of Health, Office of Dietary Supplements

Linus Pauling Institute Micronutrient Information Center

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Renew Your Natural Radiance with Celavive Skincare

Restore moisture and support your skin’s natural ability to reduce the visible signs of aging.

The Science of Glowing, Healthy-Looking Skin

Revive your most luminous skin with Celavive skincare. Inspired by a deep understanding of the needs of your skin, Celavive is designed to bring your complexion to life. Each product contains science-based cosmetic ingredients and vital nutrients to replenish, balance, and support your skin’s youthful appearance.

In only a few short weeks of using the full regimen, you will see beautiful results:

  • Brighter, healthy-looking skin
  • Enhanced look of firmness
  • Visibly reduced fine lines and wrinkles
  • Improved hydration
  • Appearance of soft, smooth texture
  • Visibly even skin tone

Skin Basics

When it’s healthy, your skin is very resilient. The skin cells actively produce water-binding chemicals, lipids, and structural proteins needed to form a barrier that defends against toxins and retains moisture for a healthy appearance. This naturally protects the soft elastic tissues that keep skin looking young.

However, genetic and hormonal changes linked with normal aging—along with other lifestyle factors—can change the appearance of your skin. These visible changes can show up as wrinkles, dryness, sagging, and uneven skin tone. Depending on how your skin reacts to these factors, you may be able to identify your skin type.

Celavive skincare products work together to rejuvenate a youthful look by supporting healthy skin and a strong barrier.

The Best of Science and Nature

Two exclusive technologies found in Celavive products deliver visible improvements in the appearance of visible expression lines, wrinkles, dullness, and sagging.

BioPeptide-CS

Nourish your skin’s natural processes that defend against visible aging with the Celavive BioPeptide-CS. USANA InCelligence Technology features targeted botanicals and bioactive peptides that help improve the appearance of skin for a visibly smoother, more youthful-looking complexion. By working with your skin cells, this powerful complex delivers results that are unique to your personalized beauty needs.

Olivol24

Reveal your natural radiance by replenishing deep hydration to your skin for up to 24 hours with Olivol24. USANA’s unique olive-fruit extract plus watermelon, apple, and lentil fruit extracts work together to support your skin’s natural moisturizing processes. In only one use, skin looks plump, smooth, and youthful.

Skin science has shown that the appearance of youthful, healthy skin can be preserved or renewed with the use of the right beautifying ingredients. Plant extracts, nutrients, and peptides are some of the key ingredients found in USANA Celavive products.

The entire Celavive line is gluten-free, contains no harsh chemicals or parabens, and has been dermatologically tested.

The Regimen that Delivers Results

To let your youthful glow shine through, make sure to use products designed for your skin type. And apply your products in the correct order to get the most out of your skincare routine.

Step 1. Cleanse

Don’t let grime dull your glow. Use a gentle cleanser to remove impurities without over-stripping the natural oils from your skin. This will help prepare your skin for application of additional skin care products and/or makeup.

  • In the morning, cleansing will not only refresh your skin. It’s also helpful for removing any sweat, excess oil, dead skin cells, etc. that may have accumulated overnight.
  • At night, it’s essential to wash off the day. And water alone won’t do the job. Remove makeup with a makeup remover. Then cleanse away dirt, pollutants, and oily residue to leave your skin feeling fresh.
  • Three times a week cleanse and enhance by exfoliating to remove any dead surface skin, purify pores, and revive your complexion.
  • Makeup Remover
    • Conditioning Makeup Remover
      • Free from harsh chemicals, the gentle yet powerful micellar water removes makeup, sunscreen, and pollutants. Most effective when used as the first step in a double-cleanse routine, ensuring a deep, thorough cleanse for refreshed skin.
      • Skin type: Suitable for oily, dry, or combination skin types.
      • Use AM
      • Learn More
    • Bi-Phase Makeup Remover
      • Gently removes long-wear makeup, waterproof makeup, as well as dirt, oil, and impurities without leaving a greasy residue, leaving your skin feeling clean and refreshed.
      • Skin type: Suitable for oily, dry, or combination skin types.
      • Use PM to remove makeup
      • Learn More
  • Cleanser
    • Creamy Foam Cleanser
      • Deeply cleanses, exfoliates, and hydrates, removing impurities while preserving the skin’s moisture for a smoother, more radiant complexion.
      • Skin type: Suitable for oily, normal, or combination skin type.
      • Use AM/PM
      • Learn More
    • Postbiotic Calming Cleanser
      • Gently dissolves dirt while postbiotics help to balance and support your skin’s natural moisture barrier.
      • Skin type: Suitable for all skin types, especially sensitive of blemish-prone skin.
      • Use AM/PM
      • Learn More
    • Exfoliating Scrub + Mask weekly
      • Dual-action, scrubbing formula gently exfoliates with a pollution-fighting charcoal to help remove stubborn impurities; use weekly.
      • Skin type: Suitable for all skin types.
      • Use 1-2 times per week
      • Learn More

Step 2: Prep

One of the most important steps in your routine, toner begins to restore moisture balance and will help you get the most out of your other skincare products.

  • Perfecting Toner: Instant Refresh
    • Balances skin’s pH, replenishes hydration levels, and primes the skin with cosmetic-grade actives for enhanced product absorption—leaving your complexion visibly refreshed and glowing.
    • Skin type: Suitable for all skin types, including sensitive skin.
    • Use daily before your skincare routine
    • Learn More

Step 3: Correct

Serums, masks, and eye treatment products deliver more concentrated active ingredients than you can get from a moisturizer. They are the best way to support your skin’s natural barrier against environmental stressors and help maintain the appearance of skin exposed to visible signs of aging. These products are essential for effectively preserving the look of youthful skin tone, texture, and firmness.

  • Serums
    • Vitalizing Serum: Repairs skin
      • Reduces wrinkles, boosts hydration, and firms skin, delivering a youthful, plump complexion while supporting your skin’s natural barrier against environmental stress.
      • Skin type: Best for dull, tired, or lackluster skin that needs revitalization and a radiant boost.
      • Use AM or PM
      • Learn More
    • Resurfacing Serum
      • 4-in-1 Serum formula helps skin feel softer and smoother with an immediate glow after just one use.
      • Skin type: Suitable for oily, normal, or combination skin types.
      • Use AM or PM, make sure to apply sunblock in the morning.
      • Learn More
    • Postbiotic Rescue Serum
      • For extremely sensitive skin, visibly reset and balance the appearance of stressed-out, blemish-prone skin.
      • Skin type: Suitable for all skin types, especially sensitive or blemish-prone skin.
      • Use AM or PM
      • Learn More
  • Masks
    • Hydrating + Lifting Sheet Mask
      • Noticeably lifts and smooths the look of your skin while providing it with intense hydration.
      • Skin type: Suitable for all skin types.
      • Use AM or PM
      • Learn More
  • Eye Treatment
    • Triple Action Eye Cream: Brightens, firms, and rejuvenates delicate skin around the eyes and mouth to improve the appearance of deep expression lines.
      • Visibly softens the appearance of fine lines around the eyes, mouth, and chin, while helping improve skin’s elasticity for a smoother, more youthful-looking complexion.
      • Skin type: Suitable for all skin types.
      • Use AM/PM
      • Learn More

Step 4: Hydrate

Dermatologists agree, retaining and replenishing moisture is key for healthy-looking, vibrant skin. (Even oily skin can become dehydrated and needs to have water restored.) Treat your skin to a high-quality moisturizer morning and night to complete your daily skincare routine.

  • In the morning, hydrate and protect with a moisturizer that also contains a broad-spectrum sunscreen. UV rays are one the biggest contributors to visible wrinkles and minor discoloration associated with normal aging. If you use a daytime moisturizer that doesn’t contain SPF, be sure to follow with a separate sunscreen.
  • At night, ensure a beautiful morning with a replenishing moisturizer that also contains targeted ingredients to help rejuvenate and repair the look of your skin.
  • AM Products:
    • Protective Day Lotion SPF 30
      • Protect your skin from sun rays for a luminous, hydrated glow.
      • Skin type: Ideal for those with oily or extremely sensitive skin.
      • Use AM before sun exposure
      • Learn More
    • Protective Day Cream SPF 30
      • Defend against the leading cause of premature skin aging while offering intense moisture for a healthy-looking complexion; ideal for those with normal, dry, or sensitive skin.
      • Skin type: Ideal for those with dry, sensitive skin.
      • Use AM before sun exposure
      • Learn More
  • AM/PM Products:
    • Radiant Facial Oil
      • Improve the appearance of discoloration and visible skin aging through super botanical oils that absorb quickly for skin that feels soothed and hydrated.
      • Skin type: Suitable for all skin types, especially those needing extra moisture and radiance.
      • Radiant Facial Oil can be used by itself or combined with other moisturizers or serums in your regimen. Massage 3–5 drops of oil gently onto face, neck, and decolletage. Follow with moisturizer.
      • Learn More
    • Contouring Face & Neck Crème
      • Boosts moisture production for a fuller, smoother look while reducing the appearance of wrinkles and expression lines.
      • Skin type: Suitable for all skin types.
      • Use AM/PM
      • Learn More
    • Postbiotic Soothing Moisturizer
      • Support and boost your skin’s moisture barrier while nourishing your skin and reducing the appearance of redness.
      • Skin type: Suitable for blemish-prone, stressed, or sensitive skin with dryness, redness, or a weakened moisture barrier.
      • Use in the AM/PM after serum, apply to face and neck
      • Learn More
    • Postbiotic Barrier Balm
      • Replenish your skin’s moisture barrier to promote a happy and balanced complexion.
      • Skin type: Suitable for dry, sensitive, and blemish-prone skin types.
      • Use in the AM/PM on clean face, neck, or any dry, flaky, or irritated areas.
      • Learn More

Frequently Asked Questions About Celavive Skincare

The name Celavive® represents the knowledge that your skin cells are alive, working together to provide protection from environmental elements, and supporting healthy beautiful skin. Celavive combines the best of science to awaken your skin cells natural ability to activate natural renewing abilities within your own skin for beautiful looking skin.

All of the Celavive products are gluten-free. The raw ingredients do not contain any gluten containing ingredients and independent testing did not detect and gluten (<20 ppm).

In the US there is not an official standard or requirement for a product to be labeled as hypoallergenic, so this designation has little meaning. Each Celavive product contains numerous naturally derived ingredients, making it possible for a person to be sensitive to a product.

The ingredients used in this product line have been thoroughly researched for safety and efficacy and should be appropriate for most individuals. If someone has a known sensitivity to skincare products or a specific ingredient it will be important to check product ingredient lists to determine if they are appropriate for use.

If you have known sensitivities to skincare products, it may be beneficial for you to test the products on a small area of your skin (the inside of your elbow, wrist, or the side of your neck) prior to applying it to your face to determine if you are sensitive. Potential reactions will typically occur within 24 hours, but may take up to 72 hours.

The Celavive Cell-Signaling Complex is made up of two bioactive peptides and two botanical extracts: Palmitoyl Tripeptide-38, Hexapeptide 48 HCl, southernwood extract, and coffee-seed extract.

These active ingredients bind to key cell receptors to support and send signals that can help counteract visible signs of chronological aging and lifestyle stress. These functions include preserving a healthy, balanced skin barrier and promoting the synthesis of a healthy skin matrix.

Together, the ingredients in the Cell Signaling Complex support your skin cells’ natural ability to create glowing, smooth, younger-looking skin from within.

Celavive™ is a comprehensive skin care system designed for both women and men concerned with preventing and minimizing the signs of aging. Celavive™ products are designed to cleanse, moisturize, protect, or renew, to help reveal healthy younger looking skin.

Women who are pregnant or breastfeeding should speak to their healthcare professional.

Celavive is a skin care line designed for adults concerned about minimizing the signs of visible aging. It is not designed to be used by infants or children. There are some differences between mature adult skin and the skin of infants and younger children and many health care providers routinely recommend skincare and sunscreen products designed specifically for this age group.

Celavive is not designed to treat diseases of the skin.

Results are different for each person, since we are all unique. Most people will see a difference in skin hydration and overall appearance within about two weeks. Because it can take up to 90 days for skin to renew itself through normal cell turnover, more dramatic visual results may take several weeks of regular daily use for most people.

Your skin is your outermost protective layer, and it is exposed to many environmental elements that can contribute to signs of premature aging.

Too much exposure to UV rays can lead to sunburn and impact delicate processes that affect the skin’s growth and appearance. Over time, exposure to UV rays causes the skin to lose its elasticity and to become thickened, leathery, and wrinkled.

The more exposed your skin is to the sun, the earlier your skin will show signs of aging, and as you get older, it becomes more difficult for skin to repair itself. Over time, this damage can take a toll on your skin and its underlying connective tissue. The influence of environmental and lifestyle factors is known as extrinsic aging or photo-aging.

But outside factors aren’t the only cause of skin aging. As you age naturally, your skin begins to produce less elastin causing skin to lose elasticity and decreasing skin’s resilience. Your skin also produces less collagen, which negatively affects skin structure causing the skin to appear wrinkled and less firm. This is called intrinsic aging and it is influenced by internal physiological factors including your DNA.

By proactively caring for your skin and focusing on prevention, you can minimize some of the visible signs related to aging skin. Limit sun exposure, apply sunscreen every day, and care for your skin internally. In addition to comprehensive topical support, providing your body with the micronutrients, macronutrients and adequate hydration can help to minimize the appearance of fine lines and wrinkles to maintain the appearance of healthy younger looking skin.

Many people are passionate believers that natural and/or organic ingredients must be better for their skin, but this belief is not always scientifically based or accurate. As the science behind skin care formulations evolve, new and innovative ways to create products are continuing to develop.

However, even with innovation, there are basic tenets of cosmetic development that must be followed to produce safe and effective products. From selecting the most effective raw materials to ensuring stability and shelf life, science dictates the types of ingredients most suitable for inclusion in products.

Our team of scientists thoroughly researched and reviewed the ingredients included in this innovative product line for safety, stability, and efficacy. The products have also been clinically tested in humans and the results are impressive.

Only the highest quality products ever make it from benchtop to market, and Celavive™ is the result of years of scientific innovation in product formulation and cell-signaling research brought to you by a team of highly qualified scientists.

Some may think that preservatives are a negative aspect of a product. But preservatives protect both the product and the consumer by maintaining stability of ingredients. They also prevent the growth of potentially harmful microbes that can occur from accidental contamination by the consumer or during the manufacturing process. In addition, all products that contain water must have some type of preservative system in place to maintain safety and stability. Certain types of multifunctional ingredients offer preservative properties and other benefits to the product.

Celavive products are preserved with ingredients including citric acid, sodium lactate, botanicals, oil extracts, and more.

Celavive is formulated without:

  • Parabens
  • Phenoxyethanol
  • Heavy Metals
  • Phthalates
  • BHA/BHT
  • Synthetic Dyes
  • Formaldehyde
  • Triclosan
  • Sodium Lauryl Sulfate
  • Hydroquinone
  • Coal tar

Fragrance in an integral part of the success of personal care products and Celavive products do contain fragrance.

Even products that claim to be fragrance free are not necessarily void of fragrance ingredients. In the US, the FDA has made the following regulation regarding this claim:

Fragrance free implies that a cosmetic product so labeled has no perceptible odor. Fragrance ingredients may be added to a fragrance-free cosmetic to mask any offensive odor originating from the raw materials used, but in a smaller amount than is needed to impart a noticeable scent.

Our scientists have a strong commitment to utilize the best science and latest available research to ensure the safety of products before they are marketed. They have gone to great lengths to find a fragrance that has a light mild scent that should not for be a concern for most individuals. As an additional safeguard, fragrance is added in minimal amounts and is typically listed near the very end of the ingredient list.

The ingredients that make up the fragrance contain synthetic ingredients selected for their stability, consistency and pleasing scent. The exact ingredients are proprietary and not available to disclose.

Celavive products do not contain animal-derived ingredients.

  1. Tobin D. Introduction to Skin Aging. 2017. Journal of Tissue Viability 26(1):37-46.

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Celavive Vitalizing Serum

Reveal firm, glowing skin with a concentrated blend of nutrients that includes USANA proprietary BioPeptide-CS.

Reveal Firm, Glowing Skin with Celavive Vitalizing Serum

Dramatically reduce the appearance of fine lines and wrinkles and reveal your youthful radiance with Celavive Vitalizing Serum. Applied after Perfecting Toner or Hydrating + Lifting Sheet Mask, this water-based serum delivers targeted active ingredients and supports your skin’s natural renewal processes.

Celavive Vitalizing Serum includes a highly concentrated amount of the unique peptides and botanicals in BioPeptide-CS. The formula is also packed with nutrients and supports antioxidants that help condition and replenish skin.

Celavive Vitalizing Serum begins to visibly transform the look of your skin. From the first application, you’ll see:

  • Increased firmness
  • Visibly reduced fine lines and wrinkles
  • Smooth, supple look and feel
  • Minimized appearance of pores
  • Brighter, even skin tone with reduced appearance of hyperpigmentation

Celavive Vitalizing Serum is also clinically studied to improve:

  • The appearance of wrinkles by 12%
  • Visible fine lines by 24%
  • Firm-looking skin by 6%
  • Smoothness by 16%

Made without parabens, Celavive Vitalizing Serum is safe for dry, oily, sensitive, and combination skin.

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Softens the Look of Fine Lines and Wrinkles

You may not be able to turn back the clock, but Celavive Vitalizing Serum helps refresh and revitalize the look of your skin for a more youthful appearance.

Get powerful support for your visibly stressed skin caused by environmental and lifestyle factors with BioPeptide-CS. The botanical extracts and peptides work together to promote firm, vibrant-looking skin. The complex features InCelligence Technology, designed to support the skin’s natural processes for a visibly smoother complexion.

There are a number of ways the complex promotes the look of healthy skin:

  • Helps rebalance the look of stressed skin for a smoother appearance
  • Supports the skin’s moisture barrier to promote plump, hydrated-looking skin
  • Retains building blocks of healthy skin, including collagen, elastin, and hyaluronic acid, to fight the visible signs of aging and maintain firmness
  • Provides antioxidant support to promote a brighter, more even-looking skin tone

Supporting these processes within your skin can significantly reduce the appearance of fine lines and wrinkles and improve your overall complexion.

Healthy Collagen Helps Skin Look Tighter and Firmer

Youthful-acting skin is supple and resilient. Its strength comes from the ability to act a bit like a rubber band. It bounces back after stretching. The visible effects of less elasticity are gradual sagging and increased fragility of the skin.

Maintain your skin’s youthful firmness by supporting strong collagen and elastin in your skin matrix. Collagen is vulnerable after sun exposure because the free radicals and dryness created can cause it to break down. If too much collagen is degraded, you will see wrinkles and less elasticity in the skin.

BioPeptide-CS in Celavive Vitalizing Serum targets key cellular processes that support collagen and other structural proteins from breaking down to help minimize the appearance of fine lines and wrinkles.

Similarly, Celavive Vitalizing Serum is formulated to visibly improve the look of skin affected by environmental stressors, including those associated with advanced glycation end products (AGEs). AGEs are destructive molecules formed in reactions between sugars and proteins, lipids, or nucleic acids. These molecules can cause collagen to become rigid and more prone to breakage.

Collagen weakened by AGEs can cause skin to look thin, discolored, and slack. Oxidative stress can speed this process, especially from a diet full of fried foods and refined sugars. Inhibiting some of the effects of AGEs with antioxidants helps shield healthy collagen, preserving skin’s elasticity.

Celavive Vitalizing Serum contains a Superfood Complex made with fungi extract that contains a blend of adaptogens and antioxidants to support collagen and elasticity. Vitalizing Serum is designed to visibly enhance skin’s elasticity for a firmer, more supple appearance after use. A private study showed skin elasticity improved in three hours, meaning you’ll see visibly firmer skin.

Lipids and Skin Cells Are Protected

Protecting skin cells and natural lipids from damage helps preserve skin’s elasticity and firmness. One way to protect against damage and prevent early signs of aging is through the use of antioxidants.

The concentrated BioPeptide-CS in Vitalizing Serum supports the skin’s defense against oxidative stress and nurtures the moisture barrier for a healthy, hydrated appearance. This visible brightening action is boosted by many additional protective antioxidants in Vitalizing Serum, including coenzyme Q10 (ubiquinone) and Olivol24.

Coenzyme Q10 provides antioxidant support and helps reduce the appearance of fine lines and wrinkles. It also supports a firmer, more youthful-looking complexion.

Olivol24, USANA’s proprietary blend derived from olive fruit extract, delivers 24 hours of hydration to promote a luminous, healthy-looking complexion. These two ingredients work together to visibly brighten and smooth the skin’s surface—revealing a complexion that looks vibrant and healthy.

Youthful Skin Appearance and Tone is Preserved

Melanin plays a protective role in the skin. However, when too much is produced in one area, you can see age spots, freckles, or uneven coloration. While shifts in melanin are usually normal, they can dull your natural glow and affect your confidence.

The encapsulated liposomal bakuchiol in Vitalizing Serum promotes a youthful-looking complexion. This plant-based is delivered through lipid vesicles to enhance absorption and promote visible skin benefits.  It supports balanced melanin production and visibly even skin tone—all with a gentler touch than traditional retinoids.

Note: Always make sure you have any questionable spots or freckles inspected by your dermatologist.

Clinical Studies

An eight-week study was conducted to evaluate the efficacy of Celavive Triple Action Eye Cream on the appearance of the skin around the eyes. The study included 36 women between the ages of 35 and 75, representing diverse racial backgrounds and a range of skin types, including combination, dry, and normal. Participants presented with mild to moderate under-eye puffiness, dark circles, fine lines, wrinkles, and a lack of firmness or radiance.

Subjects were instructed to apply the test material twice daily as directed to the skin around the eyes, between the brows, the marionette lines, nasolabial folds, cheeks, and jawline. The first application was performed in the clinic immediately following baseline assessments. Product use continued for eight weeks, with measurements taken at baseline, week 2, week 4, and week 8 to assess improvements in skin appearance.

Results show that under the conditions of the test, Vitalizing Serum demonstrated a noticeable improvement in the appearance of fine lines— nearly 25% around the eye area, close to 20% on the forehead, and more than 15% across the upper lip and chin area.

This graph shows the results at week 8 of the study. Subjects saw an improvement in skin smoothness, particularly in the eye area, forehead, chin area, upper lip, and cheeks.

% Improvement From Baseline to Week 8

Nutrients Are Restored to Nourish Skin Cells

If your skin is stressed, it may be low on crucial nutrients it needs to keep looking healthy. Support your skin’s natural glow with Celavive Vitalizing Serum. The extract used in the formula is deeply penetrating for maximum benefit to the look and feel of your skin.

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Key Ingredients

See full list of ingredients
See glossary of Celavive Ingredients

Usage

Directions: After applying toner, apply 2–3 pumps of product evenly across face and neck, in upward and outward motions.

Caution:  Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs.

Ideal For

  • All skin types

Frequently Asked Questions About Celavive Vitalizing Serum

Please submit questions below.

  1. Briggaman A, Wheeler C. The epidermal-dermal junction. Journal of Investigative Dermatology 65.1 (1975): 71-84. Web. 08 June 2017.
  2. Gemede H. “Nutritional quality and health benefits of okra (Abelmoschus esculentus): a review.” Journal of food processing and technology 06.06 (2015): n. Pag. Web. 9 June 2017.
  3. Aburjai T, Natsheh F. “Plants used in cosmetics.” Phytotherapy Research 17.9 (2003): 987-1000. Web. 009 June 2017.
  4. Draelos ZD.  Cutis 81.1 (2008): 87-89. Web. 09 June 2017.
  5. Mylonas C, Kouretas D. 1999. Lipid peroxidation and tissue damage. In Vivo 13(3): 295-309. https://www.ncbi.nlm.nih.gov/pubmed/10459507
  6. Jadoon S, et al. 2015. Ox Med Cell Long 709628: 17 pages [page numbers not noted]. https://www.hindawi.com/journals/omcl/2015/709628/abs/
  7. Nassiri-Asl M, Hosseinzadeh H. 2016. Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update. Phytoth Res 30(9): 1392-1403. http://onlinelibrary.wiley.com/doi/10.1002/ptr.5644/full
  8. Baumann LS. Less-known botanical cosmeceuticals. Dermatologic Therapy. 2007;20(5):330–342. https://www.ncbi.nlm.nih.gov/pubmed/18045358
  9. Pownali T, Udenigwe C, Aluko R. 2010. Amino Acid Composition and Antioxidant Properties of Pea Seed (Pisum sativum L.) Enzymatic Protein Hydrolysate Fractions. J Agric Food Chem 58(8): 4712-4718. http://pubs.acs.org/doi/abs/10.1021/jf904456r
  10. Pittayapruek P, et al. 2016. Role of Matrix Metalloproteinases in Photoaging. Int J Mol Sci 17(6): 868. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926402/
  11. Meissner M, et al. 2011. AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes. Exp Derm 20(5): 425-429. http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2011.01253.x/full
  12. Pérez-Sánchez A, et al. 2016. J Dermatol Sci 84(2): 169-177. https://www.ncbi.nlm.nih.gov/pubmed/27528586
  13. Miroliaei M, Khazaei S, Moshkelgosha S, Shirvani M. 2011. Inhibitory effects of Lemon balm (Melissa officinalis, L.) extract on the formation of advanced glycation end products. Food Chem 129(2): 267-271. http://www.sciencedirect.com/science/article/pii/S0308814611005887
  14. Jariapamornkoon N, Yibchok-anun S, Adisakwattana S. 2013. Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity. BMC Complement Altern Med 13: 171. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716656/
  15. Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis. Bioorg Med Chem Lett 27(15): 3374-3377. https://www.ncbi.nlm.nih.gov/pubmed/28619537
  16. Chang T. 2009. An Updated Review of Tyrosinase Inhibitors. Int J Mol Sci 10(6): 2440-2475. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705500/
  17. Binic I, et al. 2013. Skin Ageing: Natural Weapons and Strategies. Evid Based Complement Alternat Med 2013: 827248. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569896/#B29
  18. Farris P. 2015. Dermatology Times. Resveratrol, the longevity molecule [Internet] [accessed 12 Dec 2017] Available at http://dermatologytimes.modernmedicine.com/dermatology-times/news/resveratrol-longevity-molecule?page=full
  19. Shi J, Yu J, Pohorly JE, Kakuda Y. 2003. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6(4): 291-9. https://www.ncbi.nlm.nih.gov/pubmed/14977436
  20. Zi SX, et al. 2009. Oligomeric proanthocyanidins from grape seeds effectively inhibit ultraviolet-induced melanogenesis of human melanocytes in vitro. Int J Mol Med 23(2): 197-204. https://www.ncbi.nlm.nih.gov/pubmed/19148543
  21. Cornaghi L, et al. Effects of UV Rays and Thymol/Thymus vulgaris L. Extract in an ex vivo Human Skin Model: Morphological and Genotoxicological Assessment. Cells Tissues Organs 201(3): 180-192.  https://www.karger.com/Article/Abstract/444361
  22. Calò R, Visone C, Marabni L. Thymol and Thymus Vulgaris L. activity against UVA- and UVB-induced damage in NCTC 2544 cell line. Mut Res/Gen Tox Env Mut 791: 30-37. http://www.sciencedirect.com/science/article/pii/S1383571815001990
  23. Velijkovic I. The Dermatologist. Mitochondria and the Skin [Internet] [accessed 13 Dec 2017] Available at https://www.the-dermatologist.com/content/mitochondria-and-skin
  24. Zielinska A, Nowak I. 2017. Abundance of active ingredients in sea-buckthorn oil. Lip Health Dis 16: 95. https://lipidworld.biomedcentral.com/articles/10.1186/s12944-017-0469-7
  25. Telang P. 2013. Vitamin C in dermatology. Indian Dermatol Online 4(2): 143-146. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673383/

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Celavive Contouring Face & Neck Cream

Lift, firm, contour, and smooth skin with formulas that feature exclusive Celavive skincare technologies.

Restore Radiant Skin with Celavive Contouring Face & Neck Cream

Reveal visibly younger-looking skin with Celavive Contouring Face & Neck Cream. Diminish the appearance of visible signs of your skin’s aging through restored moisture, creating the radiant, youthful look you want.

Whether you have sensitive, combination, dry, or oily skin, it needs to be nourished with intense moisture. You’ll get that when you include Contouring Face & Neck Cream in your Celavive skincare regimen.

Your skin will shine with these visible benefits:

  • Replenished hydration
  • Reduced visible signs of aging
  • Minimized appearance of fine lines and wrinkles

Celavive Contouring Face & Neck Cream is also clinically studied to improve:

  • Firmer-looking skin around the eye area by 11%
  • Visible elasticity around the eye area by 10%
  • The appearance of overall radiance by 18%

Celavive Contouring Face & Neck Cream is made from quality ingredients to restore your skin’s hydration, radiance, and youthful look and texture. You’ll visibly reduce the signs of aging by minimizing the appearance of fine lines and wrinkles.

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Restored Radiance is Possible with Celavive Contouring Face & Neck Cream

If you’ve had a long day, think about what your skin’s been through. Your largest organ does many jobs—protection and regulation for a start. And it’s supposed to look good doing them.

Treat your hard-working skin to luxurious moisture with Celavive Contouring Face & Neck Cream. The advanced active ingredients work to support your complexion. That way, your skin stays strong and looks youthful and radiant.

It all starts with BioPeptide-CS. USANA InCelligence Technology is utilized in Face & Neck cream to support visible skin vitality and promote a healthy-looking complexion. The complex includes ingredients like southernwood extract, coffee seed extract, hexapeptide-48 HCl, and palmitoyl tripeptide-38. These compounds work to enhance the appearance of the skin by supporting the natural functions associated with maintaining a youthful and radiant look.

For example, Hexapeptide-48 HCl supports the skin’s barrier function to create a smooth-looking skin surface overnight. Maintaining a healthy skin barrier contributes to the appearance of resilient, healthy-looking skin over time. A strong and thick skin barrier amplifies moisture retention for a visibly soft and youthful complexion.

Southernwood (Artemisia abrotanum) extract can support your skin’s lipids and protect collagen and elastin from breaking down to help maintain a youthful appearance. This compound is rich in oligosaccharides (complex sugars) that work to make the skin appear smooth and luminous.

Experience Intense Hydration

Celavive Contouring Face & Neck Cream is formulated to provide intense hydration. Dry skin is tight, rough, and can look wrinkled. Moisture changes all of that. That’s why the moisturizing ingredients help support exceptional hydration that smooths and plumps the look of skin for a youthful appearance.

Olivol24 adds deep hydration and helps balance your skin’s natural moisturizing factors. The fruit extracts in the botanical blend have been clinically shown to provide 24 hours of rich hydration after just one application.

Plum extract helps reduce the appearance of aging and delivers immediate hydration. Like many fruits, plums contain natural sugars and organic acids that are natural humectants—water-loving substances that can attract and bind water molecules from the surrounding environment. The humectants in plum extract prevent this water from evaporating from the skin’s surface, increasing your skin’s water content.

Hydration is key to healthy skin. When skin cells are hydrated, they swell. This “plumping” effect fills out the spaces between cells, reducing the visibility of fine lines and wrinkles. Similarly, hydrated skin is more pliable and resilient, affecting its ability to stretch and return to its original shape. The hydrating ingredients in Celavive Contouring Face & Neck Cream can help reinforce the skin’s moisture barrier to lock in hydration and promote a smoother, firmer appearance.

Reduce the Appearance of Fine Lines and Wrinkles

Superfood complex helps visibly smooth the skin’s surface and reduce the appearance of fine lines and wrinkles through a blend of adaptogens to support the skin’s moisture barrier.

Adaptogens support the skin’s natural balance. They are believed to help skin “adapt” to help improve the look of skin exposed to daily stressors, promoting a balanced and resilient appearance. This can lead to a more even skin tone, improved texture, and a healthier-looking complexion over time.

In addition to their balancing effects, adaptogens also contribute to strengthening the skin’s natural moisture barrier. A fortified barrier helps retain hydration, which contributes to the look of smooth, supple, and elastic skin.

The Superfood complex in Contouring Face & Neck Cream is also rich in antioxidants to help minimize the visible effects of oxidative stress and support the appearance of firm, smooth skin. As a result, the skin’s surface looks lifted and more refined.

An Approach to Youthful-Looking Skin

With the Contouring Face & Neck Cream, you’ll get a powerful formula that supports the appearance of visibly younger-looking skin. Engelhardtia chrysolepis (leaf) extract has been clinically studied for its potential to support the appearance of firm, elastic skin and reduce visible signs of aging associated with glycation.

Glycation is a natural process where sugar molecules—like glucose or fructose—bind to proteins such as collagen and elastin. This leads to the formation of Advanced Glycation End Products (AGEs), which can stiffen and weaken these structural proteins. Over time, AGEs contribute to visible signs of aging, including loss of firmness, fine lines, and dullness. By addressing visible signs of glycation, the cream helps promote a smoother, more resilient, and radiant-looking complexion.

Radiant, Youthful-Looking Skin

Refresh your skin with Celavive Contouring Face & Neck Cream. This product’s advanced combinations of powerful active ingredients will provide intense hydration for visibly younger-looking skin.

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Clinical Study

An eight-week study was conducted to evaluate the efficacy of Celavive Contouring Face & Neck Cream on the appearance of the skin in the face and neck. The study included 34 women between the ages of 40 and 70, representing diverse racial backgrounds and a range of skin types, including combination, dry, and normal. Participants presented with mild to moderate lines on the neck, marionette wrinkles, lack of visual firmness, and lack of radiance.

Subjects were instructed to apply the test material twice daily as directed to the entire face and neck. The first application was performed in the clinic immediately following baseline assessments. Product use continued for eight weeks, with measurements taken at baseline, week 2, week 4, and week 8 to assess improvements in skin appearance.

Results show that under the conditions of the test, Contouring Face & Neck Cream demonstrated a noticeable improvement in the appearance of radiance, firmness, and elasticity.

This graph shows the results at week 8 of the study. Subjects saw improvements in the appearance of skin radiance, firmness, and elasticity, particularly in the eye area.

Key Ingredients

See full list of ingredients

See glossary of Celavive Ingredients

Usage

Start with clean skin by washing your Face & Neck. Dispense on pump of the cream and apply it to your Face & Neck. Using upward, circular motions, gently massage the cream into your skin. For best results, apply the cream both AM and PM as part of your skincare routine.

Caution: Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.

Ideal For

  • All skin types

Frequently Asked Questions about Celavive Contouring Face and Neck Cream

Li, Yi-Chen, Chi-Ruei Chen, and Tai-Horng Young. “Pearl extract enhances the migratory ability of fibroblasts in a wound healing model.” Pharmaceutical Biology 51.3 (2012): 289-97. Web. 09 June 2017.

Rabouille, Thierry. Skin moisturizing compositions. Galderma Research and Development, assignee. Patent 8758805. 24 June 2014. Print.

“Macadamia Oil” Wikipedia. Wikimedia Foundation, 06 Apr. 2017. Web. 12 June 2017.

Deckard, Angela. “8 Benefits of gardenia essential oil.” Healthy Focus. healthyfocus.org. 20 June 2016. Web. 18 June 2017.

Chajra, H., B. Amstutz, K. Schweikert, D. Auriol, G. Redziniak, and F. Lefevre. “Opioid receptor delta as a globular modulator of skin differentiation and barrier function repair.” International Journal of Cosmetic Science 37.4 (2015): 386-94. Web. 16 June 2017.

Schmidt, Alfred, and Heinrich Weiland. Cosmetic or cosmetic product for firming and smoothing skin, in particular in the case of cellulite. S.W. Patentverwertungs Ges. M.B.H., assignee. Patent 5945109. 31 Aug. 1999. Print.

Cheng, Wai. “The relationship between peroxisome proliferator-activated receptors (PPAR) and cell proliferation.” American Journal of Clinical Dermatology. 9.1 (2008): 15-31. Springer Link. Web. 19 June 2017.

Lupo, Mary P., and Anna L. Cole. “Cosmeceutical peptides.” Dermatological Therapy 20.5 (2007): 343-49. Web. 19 June 2017.

Pazyar, N; Yaghoobi, R; Ghassemi, MR; Kazerouni, A; Rafeie, E; Jamshydian N. “Jojoba in dermatology: a succinct review.” G Ital Dermatol Venereol. 2013 Dec;148(6):687-91.

Meyer, J; Marshall, B; Gacula, M Jr.; Rheins, L. “Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study.” J Cosmet Dermatol. 2008 Dec;7(4):268-74.

Sethi, Anisha; Kaur, Tejinder; Malhorta, SK; Gambhir, ML. “Moisturizers: The Slippery Road.” Indian J Dermatol. 2016 May-Jun; 61(3): 279–287.

http://www.duponttateandlyle.com/sites/default/files/Skin%20Care%20Brochure%2010.11.17_0.pdf

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