The old adage “knowledge is power” has never been more relevant. In today’s knowledge economy, your cognitive function is one of the most valuable assets you have. Being able to learn, understand, and connect concepts is essential to creating the new ideas that drive success in the modern world. A recent CopaPrime+ study shows USANA’s unique cognitive-support supplement can help.*

The demand to keep learning so you can excel at daily mental tasks has led to a growing interest in brain-optimizing compounds known as “nootropics.” Individually, some of the most promising plant extracts for optimizing brain function have been American ginseng, bacopa monnieri, and coffee-fruit extract. These three nootropics are combined in USANA CopaPrime+.*

A new double-blind, placebo-controlled study assessed the effectiveness of the CopaPrime+ formula. And the results have been published (November 2019) in the journal Nutritional Neuroscience.

USANA Science Summary

  • USANA funded a double-blind, placebo-controlled research study, which was conducted by researchers from Central Queensland University and Deakin University in Australia.
  • Researchers looked at the acute (immediate) effects of consuming two tablets of CopaPrime+ on cognitive measures.
  • Participants were given a variety of scientifically validated tests before consuming CopaPrime+. They were then re-tested about 45 minutes later.
  • Those who took CopaPrime+ experienced an increase in mental efficiency and significantly improved accuracy and response times during cognitively demanding tasks.*

This is an exciting outcome that demonstrates combining three powerful nootropics in USANA’s CopaPrime+ formula is highly effective for supporting peak mental performance.*

Let’s take a closer look at the study.

CopaPrime+ Study Shows Support for Three Measures of Cognitive Function

A growing body of evidence supports the use of nootropics to aid healthy brain function. Researchers wanted to look at the effects of a combined formula. So, USANA provided CopaPrime+ to determine what effects could be expected from such a formula after a single dose. CopaPrime+ is a unique combination of American ginseng, bacopa monnieri, and coffee-fruit extracts.*

Forty healthy participants were enrolled in the study and randomized into a treatment or control group. They didn’t eat or drink (other than non-stimulating beverages) for two hours before the study. Upon arrival at the testing center, participants answered questions regarding their state-of-mind and had blood drawn to ensure healthy blood glucose levels. These measures were repeated four times during the two-hour study period.

The participants completed a variety of tests before taking two tablets of CopaPrime+ to establish a baseline. As they took the tests, images were taken of the activity in their prefrontal cortex—the part of the brain used for complex cognitive behavior and decision making. Then participants re-took the tests, with concurrent brain imaging, 45 minutes later.

After eliminating confounding factors, there were significant differences in the group supplemented with CopaPrime+ in three areas:

  1. Working memory and accuracy
  2. Speed of attention and response time
  3. Brain efficiency

Measuring Working Memory—A Key to Cognitive Performance

One of the tests in the study measured something called working memory. This is a type of short-term memory. It involves remembering a small amount of information for a short time and retaining it long enough to interact with it in some way. For example: when you read a sentence, you have to remember what came at the beginning, so that whatever comes at the end makes sense.

It seems simple. But the ability to put information together is critical for everyday life. Finding your car. Doing math in your head. Understanding a report at work. All of these tasks, and many more, rely on your working memory. This type of memory is important for decision making, problem solving, and reasoning. It is often associated with attention, completing tasks, and academic performance.

Working memory is tested using an N-back task. “N” stands for a number, which varies depending on the study protocol. The current study included 1-back, 2-back, and 3-back tasks.

Here’s how it works.

Participants are shown a sequence of letters one-by-one. Every time the test participant sees a sequence of letters, they need to indicate if the current sequence is the same as the one they saw “N” times ago.

This task used letters A to J, with a correct match appearing 25 percent of the time. Each sequence of letters was on-screen for 500 milliseconds (half of a second), with 1,500 milliseconds (1.5 seconds) between sets. The two-second total speed makes the N-back task considerably more cognitively demanding than if more time were allotted. (Try the N-back task for yourself.)

When participants saw a correct match, they pressed a spacebar on a keyboard. If they did not select an answer within two seconds, their answer was left blank.

Those who consumed CopaPrime+ improved on the 1-, 2-, and 3-back tasks in all measured criteria (time, accuracy, and error rate). The measures with the most statistical significance were the following:

  • Faster response times on the 2-back task
  • Fewer errors on the 2-back task (fewer incorrect answers selected when not left blank [blank answers were not included in scoring])
  • Greater accuracy on the 3-back task (fewer blank or incorrect answers overall)

The results indicate that CopaPrime+ offers positive benefits on working memory, which is related to many aspects of thinking and learning.*

CopaPrime+ N-back Test Results

Looking at CopaPrime+’s Effect on Attention

Researchers determined selective attention (the ability to select what you focus on) by employing one of the most well-known observations in psychology: the Stroop effect. The effect is easily understood when the task used to test it is explained.

The Stroop task asks people to look at color words. So, “red,” “blue,” “green,” etc. Sometimes that word is presented in the color it represents (e.g., the word “red” in red text). At other times, the word appears, but the color of the text is another color (e.g., the word “red” in green text). The Stroop effect is the difficulty people have when the word and color of the text don’t match up.

Participants in this study undertook two versions of the Stroop task:

  • In the “congruent” Stroop task, the words were presented in their corresponding colors (e.g., “red” in red).
  • In the “incongruent” Stroop task, words were never presented in the color that matched the text (e.g., “red” in green).

Thirty different word/color combinations were presented. Participants were asked to indicate what color the text was (not what it said). The words stayed on-screen until a key on the keyboard labeled with the color that matched the color of the text was selected. Researchers measured the time it took for a response. (You can try the Stroop task, too.)

Participants who consumed the supplement showed faster response times on the congruent Stroop task than the placebo group. So, this suggests CopaPrime+ may help you think and focus faster. *

Faster speed of attention is valuable for helping you be more effective during daily tasks. Being able to focus your attention swiftly and maintain accuracy will allow you to switch tasks with a lower time-cost. This could help you quickly ease into the flow of work and be less prone to distraction.

Studying Brain Efficiency to Help You Work Smarter

As participants took the tests in this study, their brain activity was imaged using functional near-infrared spectroscopy (fNIRS). This is a non-invasive method for looking at specific kinds of blood flow in targeted areas of the brain.

The participant wears a monitor on their forehead. And changes in blood flow are detected by measuring differences in infrared light (a form of light waves the human eye can’t see and that can pass through skin and bone). In simple terms, variances are caused by changes in how much oxygen is in the blood or in total blood volume.

A particular fNIRS measurement stood out in the study. During one of the most cognitively demanding tests—the 3-back task—researchers observed “reduced activation of the prefrontal cortex related to effortful mental demand” in those who consumed CopaPrime+.

At first, the above sentence may sound negative. Reduced activation in the brain doesn’t sound good! But in actuality, these changes in activity relate to the level of workload happening in the brain.

Having a workload that is too high (or too low) can cause a decline in cognitive performance. The reduced activation pattern observed in this study reflects a decrease in workload. Or, put another way, an increase in cognitive efficiency.

This means CopaPrime+ may help you maintain maximum mental function longer by helping the brain become more efficient.*

On a related note, a more efficient brain generally has better performance in working memory. So, the fNIRS results provide a glimpse into biological activity behind how CopaPrime+ might work to boost brain power. (This is an additional functional benefit beyond what is provided by the InCelligence Cognitive-Support Complex. The blend of bacopa and coffee-fruit targets cell-signaling pathways that optimize brain-derived neurotropic factor [BDNF]—a cognitive protein—in the brain.)

The CopaPrime+ Study is Science You Can Use

Life comes at you fast. And thanks to distractions coming from all sides, your brain has more demands on it than ever. The CopaPrime+ study shows the supplement can help you experience greater accuracy in your thinking and faster focus, with less of a drain on your mental capacity. *

And that’s after only one use. Research on the individual ingredients has demonstrated even greater benefits when used over time. So, add CopaPrime+ to your daily supplement routine. It’s scientifically shown to help you get the most out of your mental performance every day. *

https://www.scientificamerican.com/article/working-memory-how-you-keep-things-ldquo-in-mind-rdquo-over-the-short-term/

https://www.sciencedirect.com/topics/medicine-and-dentistry/working-memory

http://www.scholarpedia.org/article/Working_memory

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852635/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207727/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887505/

https://www.sciencedirect.com/topics/neuroscience/functional-near-infrared-spectroscopy

https://psychcentral.com/lib/what-is-functional-optical-brain-imaging/

https://www.frontiersin.org/articles/10.3389/fpsyt.2017.00154/full

https://journals.sagepub.com/doi/abs/10.1177/154193120004402121?journalCode=proe

 

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Safe, high-quality formulas backed by science make USANA products a smart choice. A parallel, randomized controlled study has added to the volume of scientific research that shows real health benefits when using USANA products.

In 2017, USANA funded a China Nutrimeal and Fibergy study. It was conducted on Chinese product formulas by researchers at the School of Public Health in Beijing, China. Two papers, co-authored by members of USANA’s scientific team, have been published on the study—one in the “Journal of Obesity” and the second in “Nutrition & Metabolism.”

USANA Science Summary

  • Overweight or obese individuals from the Beijing area replaced dinner with a USANA shake every day for 12 weeks. Each shake contained one serving of the Chinese formulas of Nutrimeal and Fibergy.
  • Weight decreased and improvements in body composition were observed in the meal-replacement group.
  • Measures associated with blood glucose levels and cardiovascular health either improved or were well-maintained in the meal-replacement group. (Results were more significant in men than women.)

China Nutrimeal and Fibergy Study Shows Support for Healthy Weight

Using meal replacements can be a simple, sensible way to lose weight. In fact, a systematic review and meta-analysis has shown programs that include meal replacements can lead to greater weight loss after one year than those that don’t.

Some diet types may not be so sensible. They might require replacing all or most meals. Or extreme calorie restriction. And while it’s possible to maintain this practice for a short time, a longer-term solution is needed to sustain weight loss. This was the reasoning behind the design of the China Nutrimeal and Fibergy study.

Researchers hypothesized replacing only one meal each day would be easier for the Chinese study participants to sustain. And it would cut enough calories to gradually add up to a meaningful change. So, they asked participants to replace dinner each day with a shake made from Chinese formulas of USANA Nutrimeal and Fibergy. Each shake contained 22.6 grams of protein, 11.1 grams of fat, 39.3 grams of carbohydrate, 20.9 grams of dietary fiber, and 388 calories.

Other than the daily shake, participants continued to eat the same as before.

After 12 weeks, 174 participants completed the study—91 percent of the original 192 who were included. This high percentage of completion demonstrates the intervention was sustainable for most people.

A number of body-composition measures were taken at the beginning and end of the study. Those who consumed the meal replacement shake for 12 weeks experienced the most significant improvements in the following (on average, results varied by individual):

  • Body weight, body mass index (BMI), and waist circumference each decreased by 4.3 percent
  • Body fat mass decreased 5.3 percent (7.7 percent in men, 3.2 percent in women)

Losing 4.3 percent of body weight in 12 weeks is a smart, safe rate of weight loss. Generally, those who lose weight gradually, but steadily, are more successful at keeping weight off. And even modest weight loss of five to 10 percent can mean big benefits.

Fat and Weight Loss Equal Health Gains

As noted above, Chinese participants in the 12-week China Nutrimeal and Fibergy study had meaningful reductions in waist circumference and body fat mass.

Reducing waist circumference and body fat, especially visceral fat (the fat in the abdomen), have both been strongly tied to maintained cardiovascular health. Waist circumference is important because it is an indicator of intra-abdominal fat—the fat that accumulates around organs. Too much intra-abdominal fat has been directly linked to cardiovascular risks.

The benefits of reduced body size were detectable. Researchers looked at the outcomes of 168 participants and found significant support for healthy blood pressure in men. Blood-pressure benefits were not as clear for women. One explanation for this difference could be the fact women maintained but didn’t lose as much visceral fat as men (among other possible reasons).

However, those results don’t mean the shakes weren’t beneficial for both genders.

The shakes made from the Chinese product formulas measurably helped Chinese participants maintain current levels of fat better than those in the control group. In fact, visceral fat increased in both genders in the control group (those who did not replace their meals) over the course of the 12 weeks. This indicates that drinking one shake each day helped men and women avoid fat gain.

Maintaining, not gaining, fat is helpful for preserving cardiovascular health and blood pressure.

Positive impacts on blood glucose were also seen in men and women who swapped their dinners with shakes made from the Chinese product formulas for three months. This reinforces positive results associated with weight loss and reductions in waist circumference that have been seen in other studies. Retaining normal blood glucose means the body can manage sugar properly, which is essential for maintaining long-term health and stable energy levels.

China Nutrimeal and Fibergy Study Demonstrates USANA’s Commitment to Science

USANA is dedicated to conducting thorough research that demonstrates the quality, safety, and efficacy of its products. The China Nutrimeal and Fibergy Study protocol was reviewed and approved by the Ethics Committee of Peking University Health Sciences Center.

The results of this study are encouraging. They suggest a way for overweight or obese Chinese individuals to manage their weight and support their health using Chinese formulas of USANA Nutrimeal and Fibergy. It is unclear if similar results would be seen in other populations with different formulas.

https://stanfordhealthcare.org/medical-conditions/healthy-living/obesity.html

http://www.myhealthywaist.org/evaluating-cmr/clinical-tools/waist-circumference-measurement-guidelines/waist-circumference/page/8/index.html

https://www.cdc.gov/healthyweight/losing_weight/index.html

A glossary with an alphabetical list of all the ingredients found in Celavive® Skincare products.

You can also read more in-depth information about each Celavive product, including more information about the ingredients. Links to each page are available here. 

0–9 | A–B | C–D | E–F | G–H | I–J | K–L | M–N | O–P | Q–R | S–T | U–V | W–X | Y–Z

0–9
1,2-HEXANEDIOL: Paraben- and formaldehyde-free preservative. Also an effective humectant (substance that attracts water) for dry skin.

A–B
ACANTHOPANAX SENTICOSUS (ELEUTHRO) ROOT EXTRACT: Part of a complex of three types of ginseng that provides antioxidant action for a brighter, firmer look.

ACETYL GLUCOSAMINE: Amino acid sugar that helps reduce the appearance of dark spots and unwanted variations in skin tone.

ACETYL HYDROXYPROLINE: Amino acid that adds moisture and supports the natural ceramides (part of your skin’s natural lipids) in the skin’s barrier for a hydrated appearance.

ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER: Gentle emulsifier that thickens lotions or creams to helps them glide on smoothly.

ALBIZIA JULIBRISSIN BARK EXTRACT: Also known as silk tree. Helps reduce the appearance of fine lines and loss of firmness.

ALPHA GLUCAN (see also DEXTRIN): Sugar that helps bind water to help moisturize and soften skin.

ALPINIA SPECIOSA LEAF EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS):  Botanical source of antioxidants that also conditions the skin.

AMINOMETHYL PROPANEDIOL: Blended with active compounds in skincare products to ensure they dissolve and absorb into skin properly.

ARTEMISIA ABROTANUM EXTRACT: Commonly known as southernwood extract, this compound is rich in oligosaccharides (a type of sugar) that make the skin appear smoother.

ASCOPHYLLUM NODOSUM EXTRACT: Seaweed that contains minerals and antioxidants to help nourish and deep clean your pores for a healthy appearance.

ASCORBIC ACID: Vitamin C is an antioxidant and skin-soothing agent that can help preserve formulations while providing support against the visible signs of environmental damage.

AVOBENZONE (see also UV FILTER BLEND): Sunscreen that protects primarily against UVA rays, but offers some protection against UVB.

BIS-GLYCERYL ASCORBATE: Non-ionic vitamin C derivative that provides excellent skin-moisturizing effects.

BLEND OF SEVEN BOTANICAL EXTRACTS (Paeonia Albiflora Root Extract, Paeonia Suffruticosa Root Extract, Lilium Candidum Bulb Extract, Origanum Majorana Leaf Extract, Alpina Speciosa Leaf Extract, Oenothera Biennis Seed Extract, Geranium Robertianum Extract): Unique blend of botanical extracts rich in antioxidants that contain essential oils to help preserve skincare products without the use of harsh chemicals.

BUTYLENE GLYCOL: Commonly used ingredient in cosmetics that helps to enhance the texture and application of skincare formulations.

BUTYROSPERMUM PARKII (Shea Butter): Known as Africa’s ancient beauty secret for its intense moisturizing capabilities and pleasant fragrance.

C–D
CAPRYLYL GLYCOL: A gentle moisturizer that also acts as a preservative.

CAPRYLIC/CAPRIC TRIGLYCERIDE: Compound derived from coconut oil and glycerin that adds moisture to skin.

CARBOMER: Helps suspend an insoluble solid in a liquid. Used to maintain product consistency by keeping emulsions from separating into their oil and liquid components.

CARRAGEENAN: Sugar extracted from certain species of red seaweed (Rodophyceae) that helps thicken and stabilize skincare formulas.

CELAVIVE CELL SIGNALING COMPLEX (made with InCelligence Technology®): Active ingredients that allow for effective cell communication—palmitoyl tripeptide-38, hexapeptide-48 HCL, southernwood extract, and coffee-seed extract. Supports your skin’s barrier system and enhances your body’s natural youth-preserving functions. Helps reduce the appearance of wrinkles, uneven skin tone, and large pores, while also producing a healthy glow.

CELLULOSE GUM: Helps thicken and stabilize skincare formulas.

CERAMIDE NP: Mimics natural ceramides to help skin retain moisture for a hydrated appearance.

CETEARYL ALCOHOL: Skin softener with conditioning benefits; used to improve the application and texture of skincare formulations.

CETETH-10: Emulsifier with dirt-dissolving properties that also helps active ingredients blend into a formula.

CETYL ETHYLHEXANOATE: Oil-like skin softener that helps dissolve dirt while preserving skin’s moisture.

CITRIC ACID: Alpha hydroxy acid derived from citrus fruits that serves as a natural preservative and pH (acidity) adjuster.

CITRULLUS LANATUS (Watermelon) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): One of nature’s few materials to contain citrulline, which helps condition the skin and lock in natural moisture.

CITRUS PARADISI (Grapefruit) FRUIT EXTRACT: Contains vitamin C and other antioxidants to promote an even, bright appearance.

COFFEE (Arabica) SEED EXTRACT(see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Plant-based ingredient that has advanced antioxidant properties and has been shown to contribute to smoother, healthy-looking skin.

CYCLODEXTRIN: Blends with pea protein to promote absorption into the skin.

CYCLOPENTASILOXANE: A skin-safe silicone fluid that enhances product texture and application.

DEXTRIN: Water-soluble carbohydrate used to improve formula texture. Helps lock in your skin’s natural moisture for a radiant look.

DICETYL PHOSPHATE: Enhances texture of skincare formulas while also conditioning skin.

DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE: Broad-spectrum UV filter that also helps stabilize other UV filters.

DIMETHICONE: Gentle, lightweight silicone that forms a protective hydrating layer on the skin to help retain natural moisture by preventing water loss.

DISODIUM EDTA: Preservative that protects integrity of active ingredients and maintains texture of formula.

DIPENTAERYTHRITYL TRI-POLYHYDROXYSTEARATE: Skin-conditioning liquid with excellent water-holding capability.

DIPHENYLSILOXY PHENYL TRIMETHICONE: Conditioning agent that enhances product texture and application on skin.

DIPROPYLENE GLYCOL: Stabilizes product texture.

DIISOPROPYL SEBACATE: Boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling hydrated and silky.

E–F
EPILOBIUM ANGUSTIFOLIUM FLOWER/LEAF/STEM EXTRACT: Brightens, balances, and provides antioxidant protection to the complexion.

ETHOXYDIGLYCOL: Supports effectiveness of UV absorbers.

ETHYLHEXYL PALMITATE: Gentle skin conditioner that enhances texture of skincare formulations without interfering with effectiveness of sunscreens.

FRAGRANCE: A combination of primarily botanical extracts that add a pleasant aroma to skincare products to enhance the overall experience.

G–H
GARDENIA FLORIDA EXTRACT: Flower extract with antioxidant properties that helps refresh and revive the look of dull, tired skin.

GERANIUM ROBERTIANUM EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Soothing botanical extract that helps support skin cells for a bright, youthful appearance.

GINKGO BILOBA LEAF EXTRACT: Contains high levels of the antioxidant quercetin, which plays a role in fortifying skin against environmental stress and visible aging.

GLUCOSYL CERAMIDE: Rice-derived ceramide that supports natural lipid production and moisture retention in the outermost layers of the skin, providing a healthy glow.

GLUCOSYL HESPERIDIN: Powerful phytonutrient from citrus plants that can help revitalize the look of dull, dry skin caused by stress and climate changes.

GLYCERIN: Preserves and attracts water in the skin’s outer layer for moisturizing effects that help skin maintain a healthy look and feel.

GLYCERYL STEARATE: Emulsifier that helps remove dirt and makeup while maintaining skin’s natural moisture.

GLYCERYLAMIDOETHYL METHACRYLATE/STEARYL METHACRYLATE COPOLYMER: Reduces the appearance of wrinkles by mimicking naturally produced ceramides, which are critical to the appearance of smooth skin texture and even tone.

GLYCINE SOJA (Soybean) SEED EXTRACT: Plant-derived ingredient that adds moisturizing benefits.

GLYCOL DISTEARATE: Pearlescent emulsifier and foaming agent that also helps condition the skin.

GLYCOSAMINE: An amino acid sugar that can help replenish moisture and soothe the skin.

GLYCOSYL TREHALOSE: Sugar that helps support ideal levels of skin moisture.

HELIANTHUS ANNUUS (Sunflower) OIL (see also HORUS K COMPLEX): Hydrating plant oil to give skin a youthful appearance.

HEXAPEPTIDES 9 AND 33: Hexapeptides 9 and 33 reduce the visual intensity of facial wrinkles.

HEXAPEPTIDE-48 HCL (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Hexapeptide-48 HCL counteracts the visible effects of chronological and lifestyle-stress aging by targeting a new category of skin receptors.

HIPPOPHAE RHAMNOIDES OIL: Also known as sea buckthorn oil. Rich in vitamin C, fatty acids, and powerful carotenoids to replenish skin’s hydration and defend against environmental elements.

HOMOSALATE (see also UV FILTER BLEND): Sunscreen that absorbs UVB rays.

HORUS K COMPLEX (Rosa Canina Fruit Oil, Avocado Oil, Apricot Oil, Sunflower Seed Oil): A blend of naturally derived plant and vegetable oils that are rich in vitamin K, which helps diminish the appearance of dark circles.

HYALURONIC ACID: Valuable skin-replenishing agent that has restorative abilities and can help enhance your skin’s natural moisture content for a noticeably plump appearance.

HYDROGENATED STARCH HYDROLYSATE: A hydrating sugar.

HYDROLYZED COLLAGEN: Consists of water-soluble peptides of various molecular weights that are rich in amino acids, which help support the natural production of a healthy skin matrix for a more youthful look.

HYDROLYZED CORN STARCH: Supports delivery of Olivol® Botanical Blend to skin and helps absorb oil.

HYDROLYZED HIBISCUS ESCULENTUS EXTRACT: Okra extract can help reduce the appearance of fine lines and wrinkles caused by repeated mechanical motions, like smiling.

HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER: Thickener that enhances consistency and stability of skincare formulations. Also gives product a silky feel on the skin.

HYDROXYPROPYL CYCLODEXTRIN: Helps provide stability to palmitoyl tripeptide-38.

I–J
ILLICIUM VERUM (Anise) FRUIT EXTRACT: Part of a botanical preservative system that also offers skin-conditioning benefits.

ISODECYL NEOPENTANOATE: Part of a blend of ingredients that boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling silky and supple.

ISOPENTYLDIOL: Helps attract and retain moisture for a hydrated appearance.

ISOPROPYL LAUROYL SARCOSINATE: Amino-acid from coconut fatty acids that offers non-greasy moisturizing for a hydrated look and smooth feel.

JOJOBA ESTERS: Oil-free skin softener derived from the desert plant jojoba that’s similar to sebum naturally found on skin. Promotes healthy appearance and even skin tone by increasing moisture; supporting skin barrier function; and reducing dryness and roughness.

K–L
LACTOBACILLUS/GRAPE JUICE FERMENT FILTRATE: Moisturizer with natural skin-conditioning properties.

LACTOBACILLUS/SOYBEAN EXTRACT FERMENT FILTRATE: Gentle skin-conditioning agent that contributes to a balanced, healthy-looking complexion.

LAURIC ACID: Moisturizing fatty acid found in coconut oil that offers gentle cleansing properties.

LAURYL LACTATE: Part of a blend of ingredients that boosts efficacy and application of sunscreens by helping them spread evenly on the skin. Also leaves skin feeling silky and hydrated.

LAURYL PCA: Moisturizer that helps condition the skin.

LECITHIN: Combines with sea buckthorn oil to enhance penetration and promote a healthy appearance.

LENS ESCULENTA (Lentil) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Plant-based ingredient that helps enhance moisture content in the skin for a long-lasting, hydrated look and feel.

LILIUM CANDIDUM BULB EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Extract from the bulb of the white Madonna lily that helps brighten and hydrate complexion.

LINALOOL: Natural fragrance.

LONICERA JAPONICA (Honeysuckle) FLOWER EXTRACT: Part of a botanical preservative system that also helps condition the skin.

M–N
MACADAMIA TERNIFOLIA SEED OIL: Contains high concentrations of palmitoleic acid, which helps increase hydration and plump the appearance of the skin.

MALIC ACID: Alpha hydroxy acid used in skincare formulations to promote healthy skin renewal for smoother-looking texture. Also helps balance the formula’s pH levels.

MALLOW FLOWER EXTRACT: Enhances texture and helps add moisture to soothe dry skin.

MANNITOL: Naturally derived sugar alcohol that serves as an effective skin conditioner by helping to reduce the loss of moisture.

MALPIGHIA PUNICIFOLIA (Acerola) FRUIT EXTRACT: Powerful antioxidant and added source of vitamin C.

MELISSA OFFICINALIS LEAF EXTRACT: Lemon balm extract that helps gently cleanse the skin. Also has antioxidant properties.

MENTHYL PCA: Skin conditioner with a cooling sensation to soothe the skin.

METHYL METHACRYLATE CROSSPOLYMER: Texture enhancer that also absorbs oil.

METHYLPROPANEDIOL: Helps enhance absorption of active ingredients and leaves a smooth, dewy finish on the skin.

MICA: Boosts effectiveness of sunscreens by helping them spread evenly for consistent coverage.

MYRISTIC ACID: Saturated fatty acid that creates lather or foaming effects for gentle cleansing.

NATTO GUM: Added to HORUS K COMPLEX. A fermentation product of soy that is a hydrating source of vitamin K.

O–P
OCIMUM BASILICUM HAIRY ROOT CULTURE EXTRACT: Antioxidant that supports your skin’s natural defense against the visible signs of aging caused by overexposure to the sun.

OCTINOXATE (see also UV FILTER BLEND): Sunscreen that absorbs UVB rays.

OCTOCRYLENE (see also UV FILTER BLEND): Moisturizing sunscreen that absorbs UVB light and also helps stabilize Avobenzone, which can degrade in light, over time.

OENOTHERA BIENNIS SEED EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Evening primrose seed extract that has brightening properties.

OLEA EUROPAEA (Olive) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Antioxidant that helps protect skin from environmental elements to maintain healthy appearance.

OLIGOPEPTIDE-6: Powerful peptide that helps to reduce the appearance of deep wrinkles and minimize the look of dark spots for a visible improvement in the appearance of aging.

OLIVOL™ BOTANICAL BLEND: Combines Olivol® olive-fruit extract with watermelon, apple, and lentil-fruit extracts to provide intense moisturizing effects that have been shown to increase the moisture level of the skin for up to 24 hours after just one application.

ORIGANUM MAJORANA LEAF EXTRACT (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Natural fragrance with preservative action.

PAEONIA ALBIFLORA & SUFFRUTICOSA ROOT EXTRACTS (see also BLEND OF SEVEN BOTANICAL EXTRACTS): Help protect and brighten the skin’s appearance.

PALMITIC ACID: Fatty acid found naturally in the skin that is often used in skincare products as a cleansing agent and moisturizer.

PALMITOYL TRIPEPTIDE-5: Delivers moisture and nutrients that absorb deeply into skin. Enhances the natural production of collagen and elastin, which helps firm the appearance of sagging skin and diminish the visibility of wrinkles.

PALMITOYL TRIPEPTIDE-38 (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. It works to support the natural production of key healthy skin elements, like collagen and elastin, to promote younger-looking skin.

PANAX GINSENG ROOT EXTRACT: Part of a complex of three types of ginseng that helps improve the appearance of aging by energizing and protecting skin from the signs of visible photo-damage.

PANAX QUINQUEFOLIUS ROOT EXTRACT: Part of a complex of three types of ginseng that provide antioxidant, brightening, and firming action.

PANTHENOL: Form of vitamin B5 that softens skin.

PEARL POWDER: Rich in amino acids and minerals that help support skin hydration and protect against visible signs of environmental stress.

PEG-7 GLYCERYL COCOATE: Coconut-based ingredient used in foaming cleansers to enhance texture and protect skin from drying out.

PEG-15 GLYCERYL ISOSTEARATE: Cleansing agent that provides good spreading properties and stability to creams and lotions.

PEG-20 SORBITAN COCOATE: Coconut-based cleanser.

PEG-25 GLYCERYL ISOSTEARATE: Stabilizes cleanser formulations.

PEG-40 HYDROGENATED CASTOR OIL: Enhances texture by helping to combine oil-based ingredients in water-based skincare formulations.

PENTYLENE GLYCOL: Anti-microbial agent that helps preserve skincare formulations and has moisture-binding properties.

PERSEA GRATISSIMA (Avocado) OIL (see also HORUS K COMPLEX): Antioxidant with high concentrations of phytosterols (a type of plant-based nutrient) and fatty acids that replenish skin and defend against the look of environmental damage.

PISUM SATIVUM (Pea) SEED EXTRACT: Helps protect dermal proteins and fortify your skin against the look of visible aging.

POLYSORBATE 60 & 80 (the numbers describe the physical state of polysorbate—ranges from semi-solid to liquid.): Texture enhancers that help combine oil-based ingredients in water-based skincare formulas. Help dissolve dirt.

POLYGLYCERYL-10 STEARATE: Stabilizes and enhances texture of foaming cleanser formula.

POLYMETHYL METHACRYLATE: Gives a soft feel to the product.

PORTULACA OLERACEA EXTRACT: Delivers antioxidants and fatty acids to the skin to help promote a youthful appearance.

POTASSIUM HYDROXIDE: Keeps skincare formulas balanced by attracting water to adjust pH.

PPG-6-DECYLTETRADECETH-30: Enhances texture of formula by allowing delivery of oil- and water-based ingredients together.

PROPANEDIOL: Gentle, non-greasy moisturizer that gives skin a soft feel while helping to preserve and enhance the texture of skincare formulas.

PRUNUS ARMENIACA (Apricot) KERNEL OIL (see also HORUS K COMPLEX): Non-greasy, smoothing moisturizer derived from apricot seeds.

PRUNUS LANNESIANA FLOWER EXTRACT: Extract from sakura cherry blossom that soothes and brightens skin.

PULLULAN: Natural sugar that forms a light film on the skin, which provides an immediate skin-tightening effect for a smooth appearance.

PYRUS MALUS (Apple) FRUIT EXTRACT (see also OLIVOL BOTANICAL BLEND): Skin moisturizer and a key component of the Olivol Botanical Blend.

Q–R
ROSA CANINA FRUIT OIL (see also HORUS K COMPLEX): Oil from rosehip that hydrates as it delivers antioxidants and fatty acids to the skin for a healthy look.

ROSA MULTIFLORA FRUIT EXTRACT: Antioxidant extract from Eijitsu rose that balances and brightens the complexion. Tightens the appearance of pores.

ROYAL JELLY EXTRACT: Rich in nutrients and amino acids that minimize the look of wrinkles and promote a rejuvenated appearance.

S–T
SAPINDUS TRIFOLIATUS (Soapberry) FRUIT EXTRACT: Helps create a thick, soap-like foam in gentle cleansing formulations.

SCUTELLARIA BAICALENSIS ROOT EXTRACT: Herb with antioxidant and brightening properties. Also acts as botanical preservative.

SILICA: Texture enhancer that also absorbs oil.

SODIUM CITRATE: Used to control the pH level of skincare formulations.

SODIUM HYALURONATE: A salt naturally found in skin’s hyaluronic acid that holds water to promote a hydrated appearance.

SODIUM HYDROXIDE: Used to help balance the pH of skincare formulas.

SODIUM LACTATE: Salt from lactic acid that acts as a natural preservative and exfoliant.

SODIUM PCA: Water-attracting agent that helps bind moisture in the outer layers of the skin.

SOUTHERNWOOD EXTRACT (see also CELAVIVE CELL SIGNALING COMPLEX): A key component of the InCelligence Technology in Celavive products. Southernwood extract is rich in natural sugars that help stimulate lipid synthesis and storage, increasing density to promote an appearance of “lipofilling” or plumping of the skin.

SQUALANE: This plant-based sugar effectively moisturizes the skin, giving it a visibly soft, supple look.

STEARIC ACID: Saturated fatty acids that are used as a moisturizing and cleansing agent.

TETRASODIUM EDTA: Stabilizes and helps preserve skincare formulas.

TOCOPHEROL: Naturally occurring compound related to vitamin E. Provides antioxidant activity and conditions the skin.

TOCOPHERYL ACETATE: A type of organic compound (ester) from tocopherol (combined with acetic acid). Provides antioxidant activity and conditions the skin, without leaving an oily feeling.

TRIBEHENIN PEG-20 ESTERS: Softens the skin and keeps ingredients in formula from separating.

TRIETHYLHEXANOIN: Provides non-greasy hydration for the skin.

THYMUS (Thyme) FLOWER/LEAF EXTRACT: Contains powerful antioxidant properties.

U–V
UBIQUINONE: Fat-soluble substance naturally found in the body known for antioxidant benefits. Energizes the skin for a noticeably younger-looking complexion.

UV FILTER BLEND: Comprised of four UV filters that offer broad-spectrum protection against the sun’s damaging ultraviolet (UVA and UVB) rays.

  • Avobenzone—protects primarily against UVA rays but offers some protection against UVB, as well
  • Octocrylene—a moisturizing sunscreen that absorbs UVB light and also helps stabilize Avobenzone, which can degrade in light over time
  • Homosalate—absorbs UVB rays
  • Octinoxate—an effective UVB absorber

Celavive Protective Day Lotion and Day Cream both offer SPF 30. Sun protection factor (SPF) is based on how long it takes to sunburn skin that’s been treated with sunscreen compared to no sunscreen.

VITIS VINIFERA (Grape) LEAF EXTRACT: Potent antioxidant that helps diminish visible signs of environmental damage to your skin.

VITIS VINIFERA (Grape) VINE EXTRACT: Liquid from grape and bud vines that contains resveratrol and other antioxidants. Helps smooth the appearance of wrinkles.

W–X
XANTHAN GUM: Natural thickening ingredient.

XYLITOL: Sugar alcohol used as a skin conditioner to promote balanced moisture levels and improve barrier function for healthy-looking skin.

Y–Z
ZANTHOXYLUM PIPERITUM FRUIT EXTRACT: Energizing antioxidant from Japanese pepper that also acts as a botanical preservative.

Power Peak Mental Performance with Nootropics in USANA® CopaPrime+™

USANA CopaPrime+

Help your mind focus, learn, and make and recall memories with a boost of brain nutrition made with InCelligence Technology™.*

Life moves fast. To keep pace with daily demands, you need to be at your mental best. But constant disruptions and distractions make it hard to think straight—not to mention dealing with the normal challenges of healthy aging. Help is here. Now, you can maximize your mental performance and protect long-term cognitive health with USANA CopaPrime+.*

The ingredients in CopaPrime+ deliver a boost of brain support. The formula features a potent combination of three naturally-derived nootropics—substances that support peak mental performance. American ginseng works with the InCelligence™ Cognitive-Support Complex—a blend of bacopa and coffee-fruit extract.*

CopaPrime+ nourishes your neurons (a type of brain cell) and increases levels of an important cognitive protein in your body to help deliver important benefits:

  • Support for thinking skills, alertness, and attention that aid learning and retention—even during times of stress*
  • Support for long- and short-term memory*
  • Support for keeping your brain healthy as you age to preserve mental sharpness*

It’s easy to lose focus in an ever-changing world full of packed schedules and pinging smartphones. But it is possible to take control of your cognition and reclaim your concentration.*

Give your brain nutrients that can help you maintain mental clarity, make memories that will last, and enhance your ability to think and learn—even when you’re under pressure. Whether you’re focused on family responsibilities, studying at school, or achieving career success, CopaPrime+ can help your brain keep up with the speed of life.*

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Nurture Your Neurons for a Healthy Brain

Your brain performs a multitude of activities every day with the help of many complex functions. All those functions send and receive messages (or cell signals) using neurons to get things done. These messages control conscious and unconscious movements, learning and retention, mood and emotions, memory, your senses, and more.

Your brain and nervous system work like a super speedy postal office. Messages are received, processed, then passed along until they reach their final destination. In the blink of an eye (or less), the message is sent and causes a response.

Those messages mostly travel via specialized cells called neurons. The chemicals made by neurons to carry the messages are called neurotransmitters. These chemicals travel along a nerve fiber called an axon to be passed to the next neuron at a junction called a synapse. The synapses are on the ends of branches called dendrites, which extend from the cell body to receive messages.

Your neurons are some of the longest-living cells in your body. So, keeping them healthy is key to maintaining normal brain function. New neurons can also be created in some areas of the brain, including the hippocampus—the site of learning and memory. But, that’s not the only way your brain can change, which is known in scientific circles as neuroplasticity.

The synapses between neurons can change as they adapt to new information. This is known as synaptic plasticity. That process is directly tied to learning, as it influences how well your neurons communicate with each other. Repeatedly activating synapses makes them stronger, so messages sent between neurons are “louder.”

Over the long term, this synaptic strength plays a role in how well you create and remember new memories.


Many factors can impact the strength and structure of your neurons, which is directly related to your cognitive function. Age, stress, diet, and too little exercise can all cause your brain’s communication pathways to work less efficiently.

Fortunately, there are many lifestyle habits you can adopt to support brain health and cognitive function:

  • Feed your brain a calorie-conscious, healthy diet
  • Exercise (include yoga and vigorous 35- to 40-minute cardiovascular workouts)
  • Learn new things
  • Get plenty of sleep
  • Meditate
  • Stay connected with friends

Supplements can also help provide fuel for your mind. Many nutrients in CellSentials and HealthPak have been linked to maintained brain health. This includes choline, coenzyme Q10, green tea, resveratrol, quercetin, and curcumin. Lutein, which is found in Visionex, supports strong neuron signals. And, BiOmega provides omega-3 fats to help keep brain cells fluid and functioning optimally.*

Targeted supplementation with nootropics, such as those in USANA CopaPrime+, can also be added to these healthy lifestyle habits to help promote peak mental performance.*

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CopaPrime+ Was Designed With Your Brain In Mind

When your brain can maintain strong connections, it’s primed to help you learn, concentrate, and make and recall memories. CopaPrime+ was designed with nootropics that help strengthen those connections by supporting your neural pathways’ ability to fire and wire together*

Take a closer look at the nootropics in USANA CopaPrime+.

American Ginseng

CopaPrime+ contains a potent extract of American ginseng (Panax quinquefolius). It is cultivated to deliver optimum levels of specific neuroprotective compounds (primarily ginsenosides Rg1, Rb1) to ensure effective cognitive benefits.*

Ginseng supports healthy brain function in a number of ways.*

First, it can influence healthy function of the cholinergic system. This is how your brain converts the nutrient choline into acetylcholine (ACh)—an important neurotransmitter that sends messages in the nervous system. ACh plays a role in learning, attention, and the formation of short- and long-term memory by supporting synaptic plasticity and communication.*

Ginseng is also beneficial to brain health because it acts as an antioxidant. In this way, it helps protect neurons and neurotransmitters from damaging oxidative stress.*

The herb has been used for centuries in Chinese culture to help manage occasional stress, enhance mental clarity, and promote soothing Yin energy (instead of invigorating Yang energy). Science supports these benefits. Research has shown ginseng can support a positive mood, tranquility, and mental energy.*

InCelligence Cognitive-Support Complex

The ingredients in the InCelligence Cognitive-Support Complex support a new approach to brain health. They help your body naturally increase levels of an important cognitive protein called brain-derived neurotrophic factor (BDNF).*

BDNF is one of four types of neurotrophins. These proteins control the survival, development, function, and maintenance of neurons. BDNF is found throughout the brain, including in the hippocampus. There, it supports many signaling pathways involved with neuroplasticity, including those for:

  • making new neurons
  • dendrite density (it’s better to have a lot of dendrites)
  • and synaptic strength and plasticity

Maintaining adequate levels of BDNF in the brain and body is critical for normal cognitive and nervous system function.*


Learning, mood, focus, and memory all rely on this important protein. And production of BDNF decreases as you get older, if you’re stressed, don’t exercise enough, or gain weight. But you can’t take BDNF to increase it, because it isn’t a very bioavailable ingredient.*

The good news is targeted nutrients can stimulate your body to make BDNF naturally. Two of these nutrients make up the InCelligence Cognitive-Support Complex in CopaPrime+.*

Bacopa

Bacopa monnieri (also known as brahmi or water hyssop) is an herb that’s been used for thousands of years in Ayurveda—the holistic approach to health practiced in Indian culture. There are even reports bacopa may have been used in India between 1500 and 1000 B.C. to help scholars memorize lengthy hymns. So, it’s also long been used to sharpen intellect.*

The naturally-derived extract used in CopaPrime+ has the highest amount of Serotonin Active Bacopa Glycosides. This simply means it targets cell receptors that play a major role in cognition, while also supporting a sense of well-being. *

That’s not all. In addition to increasing BDNF to nourish and restore neurons, bacopa has been shown to support the production of ACh for normal cell signaling, which is key for learning and memory. It’s also an antioxidant and can act as an adaptogen—a substance that helps your body handle the effects of occasional stress.*

Whole Coffee-Fruit Extract

The health benefits of coffee go beyond the beans you brew. The cherry fruit that those beans come from also offers valuable nutrients when harvested and processed properly. The natural coffee fruit (Coffea arabica) in CopaPrime+ is extracted using a proprietary process that preserves high levels of chlorogenic acid (a source of polyphenols). But it has low amounts of caffeine.

The unique phytonutrient profile of this coffee extract makes it more active in the body. This potency is thought to be the reason it can increase BDNF levels. The extract also offers antioxidant activity for added protection for your brain cells.*

The coffee extract in CopaPrime+ is sourced from farms certified by Rainforest Alliance, an organization committed to sustainable practices.

The above active ingredients in USANA CopaPrime+ offer benefits for your day-to-day life and also can help keep your brain healthy as you age. And, the effects occur quickly. The ingredients have been shown to increase levels of BDNF in as little as one to two hours. Continued use creates even stronger effects. Research on bacopa has shown maximum impact between six and 12 weeks.*

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CopaPrime+ is a Brilliant Way to Have a Brighter Day

CopaPrime+ is an easy way to get a daily boost of brain nutrition for studying or performing your best at work. It’s designed to support three key areas for developing your brain and dominating your day: concentration, learning and retention, and staying cool under pressure.*

Concentration

Distractions make learning more difficult and may lead to ineffective cramming sessions to catch up. And they can wreak havoc on your productivity. Technology, with all its amazing advantages, also brings information overload that can leave you feeling frazzled and scatterbrained.

When you need to focus, it’s important to be able to tune out the world, quiet the mind, and get things done.

Schedules, adequate sleep, a quiet environment, or a good pair of noise-cancelling headphones are all good strategies to help you focus. And, taking CopaPrime+ every day can help make it easier to stay alert and focused—no headphones required.*

The ingredients in CopaPrime+ have been shown to help selective attention—which is the ability to direct your awareness and ignore distractions. This means you can concentrate on whatever you need to pay attention to. CopaPrime+ also supports speed of attention, so you can get into your deep-thinking work more quickly. There’s even evidence bacopa may help you work faster—and who doesn’t want to get more done in less time?*

Learning and Memory

Faster work is the result of improved processing speed—the time it takes to do a mental task. CopaPrime+ supports information processing, learning, and retention to enhance your thinking skills. These are the skills you’ll use for any mental task, whether you’re tapping into your creativity for a writing project, evaluating a math problem, or analyzing data.*

Another key aspect of healthy mental performance is your short-term memory. Your brain must hold information long enough to form connections that will lead to true understanding. This is called “working memory.”

This type of memory is important for reasoning, decision-making, behavior, learning, and comprehension. You use your working memory to retain information in many situations, including:

  • Reading a book, article, or blog
  • Watching a video, movie, or TV show
  • Listening to a lecture
  • Working through calculations
  • Following instructions
  • Repeating a phone number after hearing it
  • Planning a driving route
  • Finding your keys

As new information comes in, it combines with information already in your working memory. This combination makes the information useful. You’ve followed the plot, learned something new, or solved a problem by putting the pieces together.

The ingredients in USANA CopaPrime+ have shown benefits for working memory and learning.*

Here’s one example: In a randomized, placebo-controlled trial, a group of 60 medical students took bacopa (300 mg) for six weeks. At the end of the study, measures of working memory, immediate recall of logical material, and language comprehension improved. Positive effects were also seen in efficiency of attention and freedom from distractibility.*

Stress Without Duress

Now, with the help of CopaPrime+, you’ve helped your brain focus and prepare to learn. But, another important factor could impact your ability to maximize your mental game: stress. CopaPrime+ can assist with that, too. That’s because this brain supplement can also help you manage the mental effects of occasional stress.*

When you start feeling the tension of demands and daily pressures, CopaPrime+ can help you stay cool, calm, and collected. Study participants have self-reported feeling less tense and more composed after using the ingredients in CopaPrime+. This is likely because the ingredients support systems in your body that influence positive mood and its ability to handle stress.*

If you’re under occasional stress and feeling overwhelmed, CopaPrime+ will help relax and focus your mind. Get additional support for your body with USANA’s Proglucamune immune-support supplement to promote daily well-being.*

Study Shows Immediate Benefits of CopaPrime+

A double-blind, placebo-controlled research study showed support for three cognitive measures only 45 minutes after participants took a single dose. Mental efficiency, accuracy, and response times during mentally demanding tasks were all impacted. Take a closer look at the exciting results of this study.*

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Stay Sharp With CopaPrime+ and Remember Moments That Matter Most

Gaining wisdom is one of the greatest advantages of aging. Your knowledge and insights can help make middle-age and beyond the best years of your life. It’s important to protect your mental performance, so you can remember the things that mean the most as you continue to learn and grow.*

If you feel like you don’t think as quickly as when you were younger, that’s normal—even if you’re in your thirties. There’s some question about when mild, age-related declines in cognitive function generally start. One 2009 study reported structural changes in the brain as early as your twenties. But, generally, research points to mid-life—your fifties and older—as the time when signs of mild cognitive decline associated with normal aging become more apparent.

The cognitive functions most affected during healthy aging are speed of information processing, memory, spatial ability (related to remembering and visualizing images), and reasoning. CopaPrime+ can help you maintain a healthy brain and nervous system, which are key to preserving mental sharpness and cognitive function as you age.*

Research on the ingredients in CopaPrime+, specifically in adults over 40, has shown benefits for learning, as well as short- and long-term memory. Benefits have been observed for the following measures after up to four months of supplementation:*

  • Verbal learning (repeating lists of words)
  • Retention of new information
  • Focus and attention
  • Processing speed
  • Short-term or working memory
  • Making memories
  • Long-term memory

CopaPrime+ can help support these functions of mental acuity by helping restore healthy levels of BDNF in your body. As you read above, BDNF is a protein that helps keep your neural networks strong and stable. And, higher levels in the brain have been associated with better maintained cognitive function later in life. *

CopaPrime+ also protects normal cognitive processing and memory. It does this by maintaining a healthy balance of neurotransmitters, including acetylcholine (ACh). This keeps information flowing throughout your brain.*

Antioxidant activity also plays a role in the brain supplement’s neuroprotective effectiveness. This activity is important because your brain cells are particularly vulnerable. To function properly, neurons need oxygen, glucose, and fatty acids, which are susceptible to attacks from free radicals. So, by neutralizing oxidative damage, USANA CopaPrime+ protects long-term neural and cognitive function.*

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Key Ingredients

  • American ginseng
  • InCelligence Cognitive-Support Complex (bacopa and coffee extract)

See full list of ingredients

Usage

Adults, take two (2) tablets daily, preferably with food.

Ideal For

  • All healthy adults over age 18
  • College students
  • Career-focused professionals
  • Mature individuals interested in maintaining mental performance and memory

Frequently Asked Questions About CopaPrime+

CopaPrime+ was not designed for use by children. The labeled dosage on CopaPrime+ is appropriate for adults over 18.

The ingredients in CopaPrime+ have been used in numerous clinical studies and tolerated well. Some study participants who consumed doses higher than those provided in CopaPrime+ experienced mild headache or digestive upset, which went away naturally. If you experience a side effect after taking CopaPrime+, try taking it with food and reducing the dose to one tablet a day, then gradually returning to the full dose, as tolerated.

There are trace amounts of caffeine from the natural coffee-fruit extract in CopaPrime+.

CopaPrime+ and Ginkgo-PS both offer antioxidant protection. Otherwise, they work through different activity in the brain. Ginkgo-PS works by increasing blood flow, which is important for delivering oxygen and nutrients to the brain. And the phosphatidylserine (PS) is a compound that helps nerve cell membranes stay fluid, so that messages are sent and received effectively. CopaPrime+, on the other hand, works primarily by helping your body make an important protein for cognition, memory, learning, and focus. Because they work by different mechanisms, there should be no reason you couldn’t take them together. However, please note that CopaPrime+ will be replacing Ginkgo-PS, which will be phased out of production as supplies run out.

https://www.medicinenet.com/script/main/art.asp?articlekey=7143

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555146/

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https://www.ncbi.nlm.nih.gov/pubmed/15585351

https://www.ncbi.nlm.nih.gov/pubmed/29614706

https://www.ncbi.nlm.nih.gov/pubmed/20590480

https://www.ncbi.nlm.nih.gov/pubmed/25778987

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https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1320681

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https://www.scirp.org/journal/PaperInformation.aspx?PaperID=36447

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https://www.ncbi.nlm.nih.gov/pubmed/25653588

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https://www.ncbi.nlm.nih.gov/pubmed/27060612

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https://www.ncbi.nlm.nih.gov/pubmed/29289576

https://qbi.uq.edu.au/brain-basics/brain-physiology

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274766/

https://science.sciencemag.org/content/361/6406/eaan8821

https://www.health.harvard.edu/mind-and-mood/12-ways-to-keep-your-brain-young

https://www.psychologytoday.com/us/blog/iq-boot-camp/201407/10-ways-improve-your-brain-health

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805706/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710114/

https://www.ncbi.nlm.nih.gov/pubmed/18683852

https://www.ncbi.nlm.nih.gov/pubmed/21130117

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021479/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758233/

https://www.ncbi.nlm.nih.gov/pubmed/23831365

https://www.tuw.edu/health/how-stress-affects-the-brain/

https://www.ncbi.nlm.nih.gov/pubmed/21401105

http://www.nutritionaloutlook.com/herbs-botanicals/study-compares-higher-antioxidant-coffee-fruit-extract-coffee-powder

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772595/

https://www.sciencedirect.com/science/article/pii/S0747563210000488

https://www.britannica.com/science/spatial-memory

https://www.ncbi.nlm.nih.gov/pubmed/17882234

https://link.springer.com/article/10.1007/s10648-018-9432z

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683339/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962567/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344987/

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

USANA Nutritional Supplements

USANA Celavive Skincare Products

USANA Personal Care Products

USANA Active Nutrition Products

Design Your Best Health with USANA Products

Taking charge of your health begins with the smart choices you make every day. USANA can help you become your best self with products that support optimal health, inside and out: Science-based supplements help support daily wellness, so you can keep up with your busy life. Balanced diet and energy products can fuel your fitness or weight-management goals. And advanced skincare and personal-care products help reveal your natural beauty.

Trust your health to USANA’s high-quality products and you can start living your healthiest, most vibrant life today.*

Follow these four simple steps to create a health regimen that supports your health goals:

  1. Start with a strong foundation by choosing the Essential Nutrition supplement that works best for you.
  2. Add Optimizers—the USANA supplements that will target your unique health needs.
  3. Select Celavive Skincare and Personal Care products to help you look as great as you feel.
  4. Round out your routine with Food and Energy products to help fuel your day.

Search USANA Products by Category

USANA Nutritional Supplements

A complete range of vitamins and supplements, from multivitamins for the whole family to targeted products designed to address your individual health needs.

Essential Nutrition

CellSentials™—Comprehensive daily multivitamin and mineral supplement that also supplies antioxidants and other important nutrients for your overall health and wellness. Features the InCelligence Complex to promote optimal cellular function.*

HealthPak™—Convenience pack with advanced nutrition for modern lifestyles. Includes morning and evening doses of the CellSentials, plus MagneCal D (a calcium, magnesium, and vitamin D supplement) and the CellSentials Booster, which is made exclusively with USANA InCelligence Technology™.*

Prenatal CellSentials™—Vitamin and mineral supplement that includes iron for women who are pregnant, breastfeeding, or who may become pregnant.*

Body Rox™—Daily vitamin, mineral, and antioxidant supplement for teenagers.*

Usanimals™—Chewable vitamin, mineral, and antioxidant supplement for children.*

Optimizers

BiOmega™—Highly purified fish-oil supplement that provides concentrated omega-3 fatty acids plus vitamin D to support many aspects of health, including cardiovascular and brain function.*

BiOmega™ Jr—Omega-3 fish-oil supplement in a tasty gel for children or people who don’t like swallowing tablets.*

Booster C 600™—Lemon-berry flavored powder that supplies ingredients shown to support immune health when you need an occasional boost.*

CopaPrime+™—Supports peak mental performance and protects long-term brain health with American ginseng plus the InCelligence Cognitive-Support Complex.

CoQuinone® 30 | CoQuinone 100—Coenzyme Q10 supplement with alpha-lipoic acid to support a strong heart.*

Digestive Enzyme—Supplies enzymes to help you digest your meals more efficiently.*

EstroPro™—Phytoestrogen supplement that helps relieve many common symptoms of menopause.*

Hepasil DTX™—Liver-support formula made with choline and the InCelligence Detox-Support Complex to support your body’s natural detoxification processes.*

Iron—Optimize your blood health and support healthy energy with help from USANA Iron.*

MagneCal D™—Contains magnesium, calcium, and vitamin D for skeletal support.*

Palmetto Plus™—Combination of saw palmetto, lycopene, and soy isoflavones to support prostate health.*

Probiotic—Probiotic supplement for digestive and immune health.*

Procosa®—Supports joint health with key nutrients, including vegetarian glucosamine, vitamin C, and curcumin.*

Proflavanol® C100 | Proflavanol C200—Powerful bioflavonoid supplement featuring USANA’s exclusive vitamin C blend (Poly C®) and grape-seed extract to support healthy circulation and more.*

Proglucamune™—Contains the InCelligence Beta-Glucan Complex and zinc to support healthy immune function, even during times of stress.*

Pure Rest™—Melatonin supplement to support natural sleep and wake cycles.*

Rest Complete—Wind Down for Sleep with USANA Rest Complete.

Stress Relief—Mood-support supplement features three adaptogens to help support the ways your body handles occasional stress.*

Visionex® | Visionex DS—Vision-support formula designed to help maintain long-term eye health, featuring lutein and zeaxanthin.*

Vitamin D—Helps prevent vitamin D deficiency and supports many aspects of health.*

Vitamin K2—Long-acting vitamin K2 that helps keep your bones and cardiovascular function strong.*

Wondering where to start?

Science shows that the majority of people would benefit the most from adding these products to their daily routine.

CellSentials™
Most dieticians recommend a broad-spectrum multivitamin, mineral, and antioxidant supplement to fill any nutritional gaps.

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BiOmega
An estimated 90 percent of people don’t consume enough omega-3 fatty acids to get the full range of their health benefits.*

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Vitamin D
A supplement is the easiest way to avoid the world’s most common nutrient deficiency.*

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USANA Celavive Skincare Products

Renew your natural radiance with USANA Celavive® Skincare products that can help support a healthy complexion and fight the visible signs of aging. Learn more about Celavive Skincare.

Postbiotic Skincare—Nourish your skin’s natural moisture barrier for radiant, healthy-looking skin with this microbiome-friendly series of products. Featuring Celavive Postbiotic Calming Cleanser, Rescue Serum, Soothing Moisturizer, and Barrier Balm.

Brightening Products—Help fade visible discoloration to see a naturally vibrant, even skin tone with this series of unique products.

Conditioning Makeup Remover—Lifts stubborn makeup from the skin while conditioning with sugar-based moisturizers.

Creamy Foam and Gentle Milk Cleanser—Gently cleanses as it balances moisture.

Exfoliating Scrub+Mask—Dual-action formula polishes and purifies skin.

Contouring Face and Neck Cream—Delivers moisture and active ingredients to the skin.

Hydrating + Lifting Sheet Mask—Noticeably tightens and smooths the look of your skin in only 20 minutes.

Perfecting Toner—Completes cleansing process, hydrates, and prepares skin for treatment products.

Protective Day Cream and Lotion—Hydrates and shields skin from the sun with a broad-spectrum SPF 30 sunscreen.

Radiant Facial Oil—A lightweight moisturizing facial oil.

Resurfacing Serum—Advanced formula targets visible dark spots and hyperpigmentation for smoother, brighter, youthful-looking skin.

Triple-Action Eye Cream—Reduces the appearance of wrinkles and fine lines around the eyes.

Vitalizing Serum—Visibly firms and brightens skin while reducing the appearance of wrinkles, fine lines, and pores.

USANA Personal Care Products

USANA® Oral Care: Whitening Toothpaste and Oral Probiotic—Works together to keep you smiling bright with whiter teeth and a clean, fresh mouth.

USANA Foods

Activate your goals with USANA Active Nutrition. Discover how this nutritional program optimizes your digestion, weight-management efforts, hydration, and overall wellness

Circulate+—Support nitric oxide production, healthy blood flow, circulatory health, and overall wellbeing.

Core Aminos—Formulated with all nine essential amino acids and combined with beta-hydroxy beta-methylbutyrate.

Marine Collagen Peptides—A ready-to-drink collagen beverage for sharing with friends or any on-the-go lifestyle.

Metabolism+—See how a metabolism supplement can support your wellness goals, and make maintaining a healthy weight is more manageable.*

Fibergy Active—Find out how fiber helps digestion and can optimize your gut health.*

Nutrimeal™—Low-glycemic meal replacement shake.

Nutrimeal Active—Reach your fitness and nutrition goals with the help of a tasty, protein-packed meal replacement shake.

Rev3 Energy® Drink—Refreshing, low-glycemic energy drink.

Rev3 Energy® Surge Pack—Convenient, ready-to-mix powder.

Electrolyte Replacement Drink Mix—Mix up a tasty way to optimize your energy and hydration.*

Detox Tea Drink Mix—A refreshing tea that helps support your digestive health.*

Peanut Butter Snack Bar—A delicious, health-friendly option to power you between meals.

Collagen Protein Bars—A high-fiber and high-protein snack that will help keep you energized throughout the day.

Whey Protein Isolate—Support muscle growth, recovery, and overall nutrition with premium, grass-fed, USANA Whey Protein Isolate.

Learn More About USANA Products

USANA Product Usage During Pregnancy and Lactation

USANA Product Allergen Chart

Which USANA Products Can Be Used By Children?

Find Relief from Common Menopause Symptoms with USANA® EstroPro™*

USANA® EstroPro™

Ease some of the effects of menopause and get back to feeling like yourself with a unique blend of phytoestrogens.*

To say the symptoms of menopause can interrupt your life is putting it mildly. Suddenly, you have your very own personal heat wave that flares up at the most inconvenient times. A full eight hours of sleep is a thing of the past. And your mood and mind can seem like they’re all over the place. You simply may not feel like yourself anymore. But, you can take control of your menopause symptoms and find relief with USANA EstroPro. This phytoestrogen supplement provides a uniquely potent blend of four clinically studied botanical extracts that can help you get back to feeling like yourself again.*

EstroPro makes it easy to add the benefits of naturally-derived, estrogen-like compounds—isoflavones from soy and red clover, plus licorice and flaxseed—to your daily life. Consistently taking two tablets a day is the key to maximizing the benefits:

  • Provides relief for many common symptoms of menopause (hot flashes and night sweats, difficulty sleeping and fatigue, mood swings, appearance of aging)*
  • Supports bone and heart health after menopause*
  • Provides gentle estrogenic effects to support balanced hormone function*

Changes associated with the transition to menopause (perimenopause) can begin as early as your thirties, but are more common in your forties. But the end of fertility that comes with menopause doesn’t mean the end of a vibrant, active lifestyle. You have a lot going on. And these years are yours to enjoy. USANA EstroPro can help you find freedom from common menopause complaints, so nothing will get in the way of feeling your best every day.*

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Menopause: The Stages, Signs, and Side Effects

A woman’s life comes with many changes—from her first menstruation cycle through the end of her reproductive cycle. Each brings its own joys and challenges. Menopause causes changes related to the natural shift to lower levels of estrogen and progesterone in the body. These shifts are triggered by reduced function of the ovaries that happens in middle age. Menopause also marks the permanent end of fertility.

You’ll encounter the term “menopause” throughout this page to describe the gradual transition that occurs in three stages:

  1. Perimenopause—or pre-menopause—is the time leading up to menopause. There is a large variation of when this can begin. Most women begin to experience the symptoms between the ages of 40 and 58. The average age is 51. And, it can last anywhere from seven to 14 years.
  2. You’ve officially made it to menopause 12 months after your last menstrual period.
  3. Post-menopause is the aptly named time after menopause. You may continue to experience some of the symptoms of perimenopause.

Every woman’s menopause experience is different. You may not experience any side effects. But more than 85 percent of women are estimated to experience at least some symptoms related to declines in estrogen. The following are some signs and symptoms of menopause:

  • Irregular periods (there’s still a likelihood you could become pregnant, so continue any birth control until you haven’t had a period for at least 12 months)
  • Mood swings
  • Weight gain
  • Hot flashes/flushes and night sweats
  • Difficulty sleeping and increased fatigue (often related to night sweats)
  • Headaches
  • Vaginal dryness
  • Changes in sex drive
  • Increased wrinkling and dryness of the skin

Fortunately, there are a number of actions you can take to help ease the transition, including adding EstroPro to your daily routine. It was designed to help provide relief from some of the most troublesome side effects of normal menopause: hot flashes, night sweats, changes in skin and hair, mood swings, and occasional sleeplessness.*

Make sure to meet with your doctor to discuss your experiences, especially if your symptoms start to disrupt your life or become painful.

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Lifestyle Strategies for Managing Menopause Symptoms

If the side effects of menopause have you feeling less than your best, there are a few approaches you can try to find relief and get back to living your life on your own terms.

USANA® EstroPro™ is a great place to start. The gentle effects of the phytoestrogen supplement can help balance hormones and ease some of the most commonly reported menopause symptoms. It was created by USANA scientists using effective, well-researched ingredients.*

Two tablets of EstroPro per day provide 48 milligrams (mg) of soy and red clover isoflavones, 105 mg of flaxseed, and 60 mg of licorice, daily. These naturally-derived ingredients are gentle and effective because they function as mild phytoestrogens, which are estrogen-like compounds found in plants. With regular use, EstroPro can help improve your quality of life during the transition to menopause and the years following.*

The North American Menopause Society also offers a number of suggestions for dealing with the change of life. Their recommendations for hot flashes and difficulty sleeping include the following:

  • Exercise regularly and do your workouts early in the day (exercising too close to bedtime could make it harder to sleep)
  • Consume a healthy diet that includes nutritious whole foods—consider adding more soy to your diet to get the benefits of their phytoestrogen properties
  • Limit caffeine, alcohol, spicy foods, and hot beverages
  • Sleep in light clothing and layer your bedding so you can add or remove as needed
  • Keep your bedroom dark, peaceful, and cool—use a fan along with a cooling pillow or mattress
  • Manage your stress and practice deep breathing when a hot flash strikes or you can’t sleep

Maintaining a healthy weight before menopause could help lessen the severity of the side effects. This is because women who are overweight or obese can be more likely to experience hot flashes, especially early in the transition.

The 5-Day RESET, and Nutrimeal can help make it easier to manage your weight. A number of other USANA products can also help support many aspects of your health during menopause. You’ll find them listed throughout the rest of this page. *

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Keep Your Cool with EstroPro—Gentle Relief for Menopause Hot Flashes

woman lying down on yoga mat meditating surrounded by wellness equipment and EstroPro

You’re going about your day when, suddenly, the top half of your body feels like you’re locked in an unbearably hot sauna. You break out into a sweat and your face turns red. You start removing layers of clothing and reaching for ice water or a fan—anything to help you cool down. It’s difficult to think about anything else until the heat wave subsides.

If this matches your experience, you’re not alone. Hot flashes (also called “flushes”) are the most common menopause-related discomfort.

Hot flashes involve an almost instantaneous flare of heat that can last anywhere from a few seconds up to five minutes. They can happen infrequently or many times a day. Sweating and flushed skin often come along for the ride. And, you may also experience a racing heartbeat. Finally, once the heat has subsided, you could feel like you’ve been blasted by a cold chill.

The scientific community refers to hot flashes as “vasomotor symptoms,” because they involve the constriction and dilation of blood vessels. Declining estrogen and changes in the part of the brain that regulates body temperature are thought to cause the vasomotor actions that trigger hot flashes.

Hot flashes are typically the worst in the first couple years of menopause. However, ethnicity, as well as lifestyle factors—like stress levels or smoking—can contribute to variations in how long you may experience hot flashes. And the symptoms can vary greatly in intensity and duration.

Fortunately, you don’t just have to put up with hot flashes. You can take back control over your day with EstroPro—a supplement that will help you keep your cool.*

There is good evidence that the ingredients in EstroPro can help relieve the vasomotor symptoms associated with menopause. The unique blend of soy, red clover, licorice, and flaxseed is designed to help reduce the frequency or intensity of hot flashes.*

Each ingredient in EstroPro has been studied in menopausal women—with the majority of research centering on soy isoflavones. When the ingredients are combined, you get broad support to help ease hot flashes:

  • Consumption of supplemental isoflavones from soy (Glycine max) has shown to result in fewer hot flashes. Effects can begin to be felt as early as six to 12 weeks after beginning supplementation. And long-term use is recommended. One meta-analysis found that hot flashes were less severe when taken for about a year.*
  • Red clover (Trifolium pretense) isoflavone supplementation has also been shown to be more effective than placebo in cutting down the number of hot flashes and reducing “overall menopausal intensity.”*
  • Small studies have indicated benefits for hot flashes with licorice (Glycrrhiza glabra) supplementation, but more research is needed.*
  • Research reviews have found that flaxseed (Linum usitatissimum) appears to offer some mild beneficial effects for hot flashes.*

Together, these ingredients provide an effective way to tame the flame of your hot flashes, so you can feel cool, calm, and collected throughout your day.*

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Manage Menopause Mood Swings and Mental Fog Caused by Fatigue with EstroPro

The disruptions of hot flashes don’t just happen during the day. Hot flashes while you’re trying to sleep cause night sweats. And waking up in bed, drenched in perspiration and feeling like you’re on fire can significantly impair your sleep. This could leave you sluggish—mentally and physically—and irritable the next day.

Over time, a lack of sleep could start a downward spiral—for your health, mood, and energy levels. Helping to relieve hot flashes and night sweats is one way EstroPro helps you manage your mood and fight fatigue during menopause.*

But the benefits of EstroPro extend beyond its effect on hot flashes. It can also provide support for maintaining normal sleep and a stable mood in other ways.*

The normal decline of estrogen during menopause does more than cause changes in how your brain regulates the heating and cooling of your body. The same changes can also impact your mood. That’s due to a decrease in the release of certain neurotransmitters (chemical messengers in the brain). This includes a drop in norepinephrine, which underlies your fight-or-flight stress response, and serotonin, which contributes to feelings of well-being and happiness.

Similarly, menopause-related changes in estrogen levels can also impact your normal sleep hormones—having an impact on your circadian rhythms. There are also effects on your endocrine hormones, which influence the functions of many different glands in your body. These include your ovaries and pituitary gland, which affect your reproductive system, among others.

The fluctuations in your various hormone systems can all add up to not feeling yourself due to poor sleep or alterations in mood. These changes are normal for women during menopause—even more so for women who experienced changes in mood due to premenstrual syndrome (PMS) in their younger years.

The fact that these symptoms are normal doesn’t make them any easier to experience every day. The ingredients in EstroPro have been shown to help lessen the impacts of menopause on your mood and sleep by offering similar activity to your natural estrogen.*

  • Soy and red clover isoflavone consumption have been associated with improved sleep and a stable mood during menopause. *
  • The active compounds in licorice have demonstrated unique function on the serotonin system, suggesting potential benefits on mood during menopause, as well.*

Another complaint of some menopausal women is experiencing brain fog—a slowdown of cognitive function. Research has confirmed that mental performance and memory can be different during menopause. So, if you’ve noticed a difference, it’s not all in your head (figuratively speaking).

Lack of sleep could be one explanation. So, use EstroPro to cut down on hot flashes and night sweats to improve your chances of getting healthy sleep. This will help you feel less tired and support your mental clarity.*

Beyond taking EstroPro to support a balanced mood, a clear head, and a good night’s sleep, there are other USANA products to support overall health. Adding a broad-spectrum supplement like the HealthPak, along with BiOmega, to a balanced diet can help you get the right foundation of nutrients to maintain your overall health and energy levels. CopaPrime+™ can help maintain memory and cognitive function. And, Pure Rest can help support your body’s sleep and wake cycle to help you get to sleep.*

Note: If the changes in your mood are severely impacting your quality of life, please talk to your healthcare provider for more solutions.

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Support Your Skin’s Ageless Beauty During Menopause

beautiful mature woman

From laugh lines to the visible effects of adventures out in the sun—a life well-lived will show up on your skin. And you can help maintain your naturally ageless beauty by supporting the health of your skin with the ingredients in EstroPro.*

There are estrogen receptors in the layers of your skin (this includes on the scalp, where they play a role in hair growth). So, as your estrogen levels gradually decline during and after menopause, the effects can show up on your complexion more quickly. Skin becomes thinner and more fragile, wrinkles and sagging may appear due to reduced collagen, and skin becomes drier.

Consuming isoflavones from soy and red clover has shown promise for maintaining the appearance of skin in middle-aged women. A 12-week study in postmenopausal women who consumed 40 mg/day of soy isoflavones in a test food showed improvements in fine wrinkles and skin elasticity.*

Similar positive results in skin texture, elasticity, and appearance have also been seen in other research. And participants in a study who received red clover extract not only reported subjective benefits in skin condition but hair condition, too.*

There’s a lot more you can do to help your skin age beautifully. In addition to a healthy diet and lifestyle habits, applying quality ingredients on your skin can also deliver visible results. Celavive Skincare uses exclusive technologies that help rejuvenate skin’s natural processes for preserving hydration and firmness for a more youthful appearance.

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Pump Up Support for Your Cardiovascular Health During Menopause with EstroPro

EstroPro surrounded by fitness gear

You have a lot to love about your life by the time you’ve hit middle age. And caring for your cardiovascular health after menopause is especially important, so you can keep enjoying life to its fullest.*

Estrogen helps protect cardiovascular health by supporting healthy endothelial function. The endothelium lines the walls of your blood vessels, where the endothelial cells control relaxation and contraction to regulate blood flow. The normal changes in endothelial function associated with menopause could at least be partially to blame for vasomotor symptoms—hot flashes.*

As your estrogen naturally declines during menopause, research has shown you can use phytoestrogens like soy isoflavones to help maintain normal endothelial function. The phenolic compounds (types of antioxidants) in flax may also help provide defense against free radical damage to endothelial cells. This means EstroPro can help support your vascular health during menopause.*

Soy, red clover, and flaxseed have also been shown to help support healthy cholesterol levels, as long as they’re already in the normal range. Red clover may provide additional support for maintaining normal triglyceride levels, too.*

You can learn more about a heart-healthy lifestyle in this article on Navigating the Cardiovascular System. For additional nutritional support, you can also help protect a strong heart with CoQuinone and help maintain healthy circulation with Proflavanol C.*

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Phytoestrogens in EstroPro Help Strengthen Support for Bone Health

woman doing yoga

The increased confidence that comes with age isn’t your only source of inner strength. A strong skeleton is also necessary to support your body through whatever may come its way.

Estrogen plays a role in your bone health. It helps keep bone remodeling balanced—the process by which older bone tissue is removed from the skeleton and new bone is created. Maintaining a balance is important so you don’t lose more bone than your body makes. But when estrogen levels naturally drop after menopause, the result can be an imbalance between the types of cells needed to create bone (osteoblasts) and remove bone (osteoclasts).

You can learn more about this process in this article on Understanding Bone Anatomy.

The rate of bone remodeling tends to increase after menopause. And it’s common for the pace of bone formation to lag behind the rate of bone resorption (the term for what happens when your body absorbs bone). This is why women lose bone more rapidly during the first four to eight years after menopause, especially in the hip, wrist, and spine.

The ingredients in EstroPro may help you maintain healthy bone mineral density during and after menopause to protect strong bones.*

Phytoestrogens can provide somewhat similar structural activity to your natural estrogen to help maintain bones. Research has shown supplementation with isoflavones can help maintain bone mineral density, as measured in the hip joint and lower spine. Most studies use soy, but red clover has also shown some benefit.*

Isoflavones have demonstrated support for maintaining bone-calcium content, promoting bone formation, and reducing the rates of resorption. And supplementation over the long-term is important—one study showed benefits over three years.*

Research has also suggested that licorice may help support healthy bone remodeling when combined with quercetin. This makes the licorice in EstroPro a great complement for the higher levels of quercetin you get with the HealthPak. You can further support strong bones by also adding Vitamin K2 and/or Vitamin D to your daily routine. (Or, if you opt to take the CellSentials instead of HealthPak, you’ll also want to add MagneCal D).

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EstroPro Delivers Unique Blend of Naturally Derived Phytoestrogens to Support Hormone Balance

EstroPro is able to help support so many aspects of health during menopause because it provides phytoestrogens—ingredients that have structural similarities to your natural estrogen. When your natural estrogen declines, the phytonutrients can attach to open estrogen receptor sites on various cells to support similar functions.*

EstroPro contains two major classes of phytoestrogens: isoflavones and lignans (which are structurally different plant compounds).*

  • Soybeans and red clover are both isoflavones. Licorice is a flavanone (which is structurally similar to an isoflavone) that also offers some estrogenic effects.*
  • Flaxseed is the richest food source of lignans.

Isoflavones are the most well-researched class of phytoestrogens. There are a number of different types of isoflavone molecules that can come from various sources. They include genistein,  daidzein, formononetin, and biochanin A. The names aren’t really important to remember. But you’ll see genistein mentioned most frequently in studies.*

USANA scientists designed EstroPro to supply a diverse formula of naturally-derived botanicals for broad benefits. Soy and red clover have similar chemical profiles. But soy contains more genistein and daidzein. Red clover delivers higher levels of formononetin and biochanin A.

woman in kitchen slicing lemons surrounded by healthy foods and a bottle of EstroPro on counter

The blend of soy and red clover, along with the added licorice extract, will give you a balanced mixture of isoflavones. This mix more closely reflects what you would get if you ate a diet that provided a healthy balance of soybeans and unfermented soy foods.*

The interest in mirroring a diet high in soy stems from the fact that Asian women tend to have an easier time transitioning through menopause. They consume considerably more soy than women in Western cultures. Because Western diets rarely contain much soy, a supplement is a convenient way to deliver their beneficial compounds.*

But not all supplements made with soy isoflavones are the same. The soy isoflavones that come from whole soybean—not soy germ—are more concentrated. And the form of isoflavone also matters. EstroPro is formulated to provide an effective amount of a highly absorbable form of soy isoflavones that come from whole soybeans for more potent activity.*

Soy isoflavones can come in one of two forms: a glycoside or an aglycone. A molecule of soy from food includes a sugar as part of its structure. This is the glycoside (glycol = sugar) form. That sugar has to be removed during digestion before the nutrients can be absorbed.

An aglycone is an isoflavone that already has the sugar removed, so it absorbs faster. USANA EstroPro is formulated to provide an effective amount of aglycones to provide the most active formula possible.

You can also increase your soy consumption by eating foods like miso, edamame, or tempeh.

The lignans from flaxseed also make EstroPro unique.

Lignans are distinctive because they only provide estrogenic activity in the body if your estrogen levels are low. If there is plenty of estrogen already available to your cells, then the flaxseed won’t provide additional estrogenic effects. This makes EstroPro a good choice, regardless of where you are in your menopause journey, because it can adapt to your needs.*

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Key Ingredients

  • Isoflavones
  • Flaxseed Extract
  • Licorice Extract

See complete list of ingredients

Usage

Women 40 and older, take two (2) tablets spaced evenly throughout the day.

Do not take this product if you are pregnant, nursing, taking a prescription drug, or have a gastrointestinal disorder or other medical condition without first consulting your physician.

Ideal For

  • Women over 40

Frequently Asked Questions About EstroPro

USANA® EstroPro™ is a phytoestrogen supplement that helps relieve common symptoms of menopause, including hot flashes, night sweats, mood swings, sleeplessness, and fatigue. It also helps maintain bone and cardiovascular health. EstroPro contains isoflavones from soy and red clover, as well as licorice and flaxseed extracts, for broad support.*

Phytoestrogens can be subtle in their effects and results will vary by individual. A meta-analyses of studies found some effect of soy isoflavone supplementation in as early as six weeks. However, the effects are greater with longer periods of use. Many studies show benefits after three to six months of use. But, a different meta-analysis estimated it can take up to 48 weeks to achieve 80 percent of the maximum beneficial effects of soy isoflavones. An informal, in-house survey found that women noticed a difference after about two months of using EstroPro.*

If you don’t eat much soy in your daily diet, it may take longer to see an effect. You can consider taking an increased dosage of up to four EstroPro tablets a day, for three to four months, to increase levels of active ingredients more quickly. Spread consumption of the tablets throughout the day.

Please consult your healthcare provider or a pharmacist before adding EstroPro (or any other supplement) to your routine to determine if it’s the right approach for you.

The majority of research in humans has shown that soy is not only safe, but it is actually beneficial for health. This includes offering support for breast and cardiovascular health. Every individual is unique, and we encourage you to discuss any concerns with your healthcare provider.*

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

A Bright Smile in Just 2 Steps: USANA® Whitening Toothpaste and Oral Probiotic

USANA oral probiotic and whitening toothpaste on white background

USANA Whitening Toothpaste and Oral Probiotic

Get a clean, fresh mouth and whiter, brighter smile with fluoride-free toothpaste and an advanced probiotic that will support your long-term oral health.*

There is power in your smile. It can make you happy, even if you’re feeling blue. It can bring joy, comfort, and encouragement to those you love. It can soften hardened hearts and draw others closer to you. But there can be a barrier between you and the world if you lack confidence in your smile due to stained teeth, bad breath, or poor oral health. USANA Oral Care products provide gentle, effective support for the health of your mouth, teeth, and gums. The fluoride-free Whitening Toothpaste and Oral Probiotic combine the power of naturally-derived and scientifically-advanced ingredients for a clean, fresh mouth and whiter, brighter smile.*

Whitening Toothpaste and Oral Probiotic are designed to be used as a system. Together, they help keep your mouth and teeth looking and feeling as great as they do after a visit to the dentist. When used together, they help support a healthy-looking smile and minty fresh breath.*

  • AM and PM: Brush away grime, food debris, and microscopic organisms as you gently polish and remove surface stains from your teeth by using USANA fluoride-free Whitening Toothpaste enhanced with ADP-1. (Read more about ADP-1 below.)
  • PM: Replenish the good bacteria in your mouth before you sleep, so they can work overnight to help protect the long-term health of your teeth, mouth, and gums with Oral Probiotic.

Brushing your teeth to keep them clean is the foundation of good oral health. And maintaining a healthy mouth can also help contribute to your overall health and wellbeing.*

USANA Whitening Toothpaste and Oral Probiotic are the right choice to help you and your family live healthfully while maintaining good oral hygiene. The formulas use naturally-based ingredients that are safe, gentle, and effective. And, they’re free from artificial sweeteners or colors. That’s something to smile about.*

USANA Fluoride-Free Whitening Toothpaste

A Brighter Way to Ban Bad Breath and Reveal a Whiter Smile

Your teeth may seem small, but they have some big jobs. Teeth give shape to your face, help you pronounce words properly, and—most importantly—allow you to chew your food.

Chewing begins to break down food as part of the digestive process. This is vital for your physical health, because it’s how your body gets the nutrients it needs to function. And, the appearance of your teeth also plays a role in how you feel about yourself. So, a healthy, bright smile is equally important for your confidence and emotional health, too.*

father holding young daughter putting toothpaste on brush

Brushing your teeth twice a day, along with regular flossing between teeth, is essential to your dental health. Brushing clears away food, grime, and plaque (a thin, sticky film that forms on your teeth), which can go a long way in preserving your oral health.*

You have a lot of choices when it comes to selecting a toothpaste. USANA Whitening Toothpaste is a safe, gentle option made without harsh chemicals or artificial flavors or colors. So, it’s a bright choice for the whole family. This fluoride-free paste is made from naturally-derived ingredients. And it’s unlike many other toothpastes on the market, because it supplies ADP-1. This postbiotic helps support the cleansing process by targeting and clearing away unwanted compounds that can dull your teeth or cause bad breath.*

You’ve likely heard of probiotics, which are live organisms that can be consumed to deliver a health benefit. Or prebiotics, which are fibers that help feed bacteria. A new area of research is something called postbiotics.

This research has revealed that, in some cases, probiotic bacteria do not need to be alive to provide a desired benefit. The compounds that the bacteria produce or that are released as their cells disintegrate are sufficient to create a response. (These compounds can include proteins and peptides, enzymes, or other acids.)

The isolated compounds are postbiotics.

A postbiotic delivers the functional components from probiotic bacteria cells. But, the bacteria are no longer alive. This allows you to get many of the same benefits of a live strain in a product that otherwise could not contain a probiotic.

Live bacteria are fragile and can easily be destroyed during processing. Or they simply don’t survive well in certain types of products—like a toothpaste. Isolating the active compounds from live probiotic bacteria creates a stable delivery form that can be used in these types of products to give you the desired benefits.

The postbiotic ADP-1 in Whitening Toothpaste is an inactivated form of the probiotic bacteria Lactobacillus paracasei. Research has shown that ADP-1 is stable and delivers the benefits of the probiotic, helping Whitening Toothpaste provide an exceptional clean that can help maintain good oral health.

USANA Whitening Toothpaste freshens breath and offers a clean that lasts for up to 12 hours. So, your mouth will look and feel clean and fresh all-day long. And it’s been shown to visibly whiten teeth for a healthy-looking smile—without using hydrogen peroxide. In fact, tests from an independent lab found that USANA Whitening Toothpaste removed 78.3 percent of surface stains (relative to the American Dental Association Reference).

Let’s take a closer look at what’s in every tube of Whitening Toothpaste.

USANA Whitening Toothpaste Ingredients

Calcium Carbonate, Silica, and Sodium Bicarbonate (commonly known as baking soda)Mild abrasives that clean and polish teeth by removing debris and surface stains without damaging tooth enamel for a whiter look.
Sea Salt Gently scrubs and polishes teeth, and also stimulates saliva to bring moisture into oral tissues for a beautiful smile.
Aloe VeraSoothes, cleanses, and helps teeth shine by leaving a slick surface that is difficult for dirt or plaque to adhere to.
Coconut OilCleanses teeth and gums with lauric acid—a medium-chain fatty acid with unique properties for supporting oral health.
SteviosideA naturally-derived sweetener extracted from leaves of Stevia that won’t cause tooth decay.
MentholRefreshes breath and mouth.
ADP-1 (Lactobacillus paracasei)

Supports cleansing process by clearing away unwanted compounds that can cause bad breath or give your teeth a dull appearance.

Research has shown that, after about eight weeks, using ADP-1 helped maintain balanced oral microflora better than placebo to help keep teeth clean for a healthy-looking smile.

There’s one ingredient commonly found in most toothpastes that you will NOT see in USANA Whitening Toothpaste: fluoride.

Many chemical-conscious consumers already drink fluoridated water and do not want to add more to their daily exposure. Using fluoride is a personal choice that’s best handled individually between a family and a trusted dental professional.

See full list of ingredients

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USANA Oral Probiotic

woman with beautiful smile taking oral probiotic

Replenish Beneficial Bacteria to Protect Your Pearly Whites and Keep Breath Fresh

Beauty sleep is a real thing. Your body does a lot of work every night to keep you well while it recovers from daily wear and tear. So, take your evening dose of supplements, like MagneCal D to supply important nutrients that support strong, healthy bones and teeth. Apply Celavive Replenishing Night Cream or Gel to protect your youthful complexion. Then protect the beauty of your smile as you slumber. How? Put the growing science of the microbiome to work for you.*

First, brush your teeth with USANA Whitening Toothpaste to cleanse away plaque, surface stains, and other substances that built up during the day. This creates a clean slate.

Then take advantage of the nighttime hours (while you won’t be eating or drinking anything) to promote the good health of your teeth, mouth, and gums. Complete your oral-care routine by replenishing some of the beneficial bacteria that can help keep your mouth clean, fresh, and healthy with Oral Probiotic.*

package of oral probiotic on nightstand to be taken before bed

Why do you need Oral Probiotic if you already brush your teeth twice a day?

The oral cavity has a distinct and diverse microbiome that influences your health—in your mouth and throughout your body. Researchers have noted that anywhere from 300 to 1,000 different species could reside in your mouth alone.

When properly balanced, the bacteria in your mouth play a number of roles, including helping break down the food you eat and acting as part of your immune defenses. But it’s possible to disrupt that balance.*

Most toothpastes, mouthwashes, or oral rinses have broad anti-bacterial action. This means they’ll remove most of the bad-breath-causing bacteria that you don’t want, but they’ll also temporarily remove the good bacteria you do. This means those products can potentially open the door to an imbalanced oral microbiome.

Cleansing products aren’t the only consideration. Factors like genetics, age, stress, and poor diet can also disrupt the natural balance of microflora in your mouth. This can leave your oral health vulnerable.*

By replenishing beneficial bacteria, Oral Probiotic supports a healthy balance to help maintain your oral health. Regular use can help promote healthy teeth and gums, as well as keep your breath fresh. (If you’re especially worried about bad breath, a tongue scraper may also help.) It also helps contribute to your overall wellbeing through improved oral care, which has been linked to many aspects of health.*

Each dissolvable lozenge of Oral Probiotic is formulated with one billion total CFU (colony forming units) of three powerful, patented probiotic strains. Each were selected for their proven effectiveness. It contains Lactobacillus brevis CECT 7480, Lactobacillus plantarum CECT 7481, and Pediococcus acidilactici CECT 8633. ‡

These strains of bacteria have been shown to work together to colonize the oral cavity so they can offer protective action. The bacteria recognize each other and stick together to form a barrier. They create a film on teeth and oral tissues that won’t be washed away by saliva. So, the probiotics act as a shield that will help preserve the long-term health of your teeth and gums.*

It is recommended that you use Oral Probiotic nightly to maintain the strength of colonization. Simply swirl a lozenge around your mouth for three to five minutes after you brush your teeth. Do not chew. It is sweetened with sorbitol and mint flavor, so it will leave a refreshing taste and clean feeling in your mouth. For best results, do not eat or drink for 30 minutes after using the Oral Probiotic tablet.

Get in the habit of using Oral Probiotic to help support your oral health, so nothing will dull your sparkling smile.*

See full list of ingredients

‡ Probiotic strains protected under patent US9192634B2 and patent pending WO2018065324A1, held by AB-BIOTICS, Inc.

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Frequently Asked Questions About Whitening Toothpaste and Oral Probiotic

USANA Whitening Toothpaste is a fluoride-free toothpaste that includes the postbiotic ADP-1 (Lactobacillus paracasei that has been inactivated to isolate and deliver stable, functional components). It’s made with naturally-derived ingredients and is free from artificial flavors, sweeteners, or colors. The toothpaste effectively whitens and cleans teeth as it freshens breath with ingredients like baking soda and sea salt. Aloe, coconut oil, and ADP-1 help provide a better, longer-lasting clean.

USANA Oral Probiotic provides a powerful blend of three patented probiotic strains. The strains were selected because they’ve been shown to survive in the oral cavity and support the health of the mouth, teeth, and gums. It also helps freshen breath. The mint-flavored lozenge works by promoting the growth of healthy oral flora (bacteria) after brushing to help maintain a healthy balance.*

The Whitening Toothpaste is suitable for children 3 years old and over. Children under 6 years old should be supervised by an adult.

The Oral Probiotic is suitable for children 6 years old and over.

We recommend you discuss if these products are right for your child with your pediatric dentist.

Your microbiome is diverse. Each part of your body has a unique community of microbes, so each area requires different probiotics to support their health. USANA Probiotic is designed using probiotic strains specifically selected to support your digestive and immune health. USANA Oral Probiotic was designed with bacteria strains specifically chosen for their ability to provide oral-health benefits.*

The USANA Oral Probiotic can be used at any time, but for best results, you’ll want to use it at night after brushing your teeth. The longer you can keep the beneficial bacteria in your mouth, the better the results. If you use the Oral Probiotic during the day, it may be less effective as it will be washed away by food or drink.

The Oral Probiotic can help freshen breath. The strength of the effects depends on different factors that are unique to you, including your diet, oral hygiene, genetics, and environment. Adding USANA Oral Probiotic, along with regular brushing, is a good way to support a healthy mouth and fight bad breath.*

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897872/

https://askthedentist.com/oral-probiotics/

http://www.medicinaoral.com/pubmed/medoralv15_i5_p677.pdf

https://www.immunology.org/public-information/bitesized-immunology/organs-and-tissues/immunity-in-the-oral-cavity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320998/

https://www.ncbi.nlm.nih.gov/pubmed/29710488

https://www.ncbi.nlm.nih.gov/pubmed/17577323

http://www.ab-biotics.com/products-en/probiotics-en/oral-care-en/ab-dentalac-pro-en.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349898/

https://www.caister.com/oral-ecology

https://www.ncbi.nlm.nih.gov/pubmed/22054727

https://www.ncbi.nlm.nih.gov/pubmed/28271469

https://www.ncbi.nlm.nih.gov/pubmed/23201354

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688201/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704030/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC120797/

https://www.ncbi.nlm.nih.gov/pubmed/28556062

https://www.mouthhealthy.org/en/az-topics/b/bad-breath

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133768/

https://www.ncbi.nlm.nih.gov/pubmed/11168719

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806962/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200013/

https://www.ncbi.nlm.nih.gov/pubmed/24174720

https://www.deltadentalins.com/oral_health/whats-in-your-toothpaste.html

https://www.researchgate.net/publication/12822103_Gingiva_teeth_and_sea_salt

https://www.authoritydiet.com/why-coconut-oil-good-teeth-pulling-toothpaste/

https://www.ncbi.nlm.nih.gov/pubmed/27084861

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382606/

https://www.ncbi.nlm.nih.gov/pubmed/12017930

https://www.ncbi.nlm.nih.gov/pubmed/19278079

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606330/

https://www.dentalhealth.org/caring-for-my-teeth

https://www.sciencedirect.com/science/article/abs/pii/S0924224416302412

https://www.sciencedirect.com/science/article/pii/S0924224417302765

https://www.ncbi.nlm.nih.gov/pubmed/23271068

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USANA® Vitamin K2 is Powerful Protection for Strong Bones and a Healthy Heart*

USANA® Vitamin K2

Keep your bones and cardiovascular function strong by making sure calcium goes where it belongs with the help of long-acting vitamin K2.*

You’re actively focused on staying healthy every day. You try to eat right, exercise, and get plenty of sleep. You take your multivitamins and maybe omega-3s or calcium. But do you wonder if you’re missing something? You might be. Vitamin K2 is an essential nutrient with important benefits for your well-being, but it doesn’t get much attention. You can add this missing nutrient to your daily diet with USANA® Vitamin K2.*

Recent research has shown vitamin K2 is critical for helping you live well today and age healthfully into the future. It’s especially important to add to your supplement routine if you take a calcium supplement. It helps your body use the mineral properly, so you can get the most out of your calcium intake.* Take one tablet of USANA Vitamin K2 a day for a double dose of benefits:

  • Helps build and maintain strong bones and teeth by ensuring calcium is deposited in bones*
  • Maintains healthy cardiovascular function by stopping calcium from being absorbed into soft tissues*

USANA’s supplement delivers an effective amount of the highest quality form of vitamin K2 to ensure maximum absorption and activity in your body. Add USANA Vitamin K2 to keep your body’s calcium moving in the right direction so you can keep your health—and your life—moving in the right direction, too.*

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The Health Benefits of Vitamin K2: A Perfect Partner for Calcium

smiling woman in convertible

Exploring the importance of vitamin K begins with another nutrient: calcium.

For decades, the expert advice was that you should consume calcium supplements to maintain your bone health. But recently that conventional wisdom has begun to shift, because calcium is only part of the story.

Nutritional science shows that balancing your calcium intake with other important nutrients is the key. You also need magnesium and vitamin D. And vitamin K is one of calcium’s most important nutrient partners to help keep your body strong and healthy.*

There are two types of vitamin K (both are provided for a solid nutritional foundation in the CellSentials):

  • Vitamin K1 (phylloquinone) supports the normal blood clotting process.* It’s found at higher concentrations in leafy green vegetables.
  • Vitamin K2 (menaquinone) is present in many body tissues and supports bone and cardiovascular health (research on its role in other aspects of health continues).* It’s found in some animal products, and in fermented foods like natto—a traditional Japanese food made from fermented soybeans.

The differences in the types of vitamin K are important. Your body will use most vitamin K1 in the liver to support the coagulation process, which is imperative to immediate survival. Very little is left over to convert to the other form. Vitamin K2 is what is needed to support functions that promote long-term health by helping your body use calcium properly.*

Small amounts of some forms of vitamin K2 can be produced by bacteria that reside in your colon. Or it can be converted from K1 in tissues. But the amount of K2 that’s naturally available in your body could be low.

The typical Western diet contains insufficient amounts of vitamin K2. And dietary sources from plants (spinach, turnip greens) have poor bioavailability. USANA offers Vitamin K2 as a supplement to give you a consistent 180 microgram (mcg) supply of this vital nutrient every day. This amount will help ensure you have enough circulating in your body when it’s needed.*

The recommended Daily Value of total vitamin K is 90 mcg for females and 120 mcg for males. However, that may not be enough to reach optimal levels of K2 for some people. Your body recycles vitamin K, but it stores very little. So, it can be depleted rapidly if it isn’t replaced by your diet. And deficiency of vitamin K also tends to increase with age.*

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What Makes USANA’s Vitamin K2 a High-Quality Product?

When you take USANA’s Vitamin K2, you can be confident you’ll get the best form of vitamin K. And you’ll get the dose stated on the label—guaranteed.

Vitamin K2 comes in several varieties, identified with MK plus a number that indicates its molecular structure. Menaquinone-4 (MK-4) and MK-7 are the only two that are available in supplement form. And their functions are the most well-studied.

USANA chose the MK-7 form for Vitamin K2 because of its flexibility and longevity. MK-7 can convert to MK-4 in the body, if needed. And MK-7 stays active in the body longer than MK-4. So, you only need to take it once a day to maintain ideal levels.*

Many raw ingredient formulations of vitamin K2 are not very stable when blended into a finished product. Unfortunately, this causes those products to lose potency quickly. So, some supplements with vitamin K on the label may not actually contain much of the nutrient by the time you consume them.

USANA Vitamin K2 uses a premium-quality form of MK-7 that is double-coated. This ingredient formulation preserves its potency better than non-coated forms.

You can also help maximize absorption by taking Vitamin K2 with a meal. Because it’s a fat-soluble vitamin, it works best when consumed alongside some dietary fat.*

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Vitamin K2 is the Glue that Helps Calcium Stick to New Bones

If you think about reinventing yourself, you probably focus on changing your hairstyle or embarking on a new career. But on the inside, your body is always getting a fresh start. It continually renews itself, day in and day out.

The bones that give you stability, which seem solid and fixed, are actively broken down and rebuilt constantly as part of your body’s normal processes. Your old bones are broken down as your body pulls calcium or other nutrients from them when needed (this natural process is called resorption). Meanwhile, the micronutrients from your diet come in to replenish what’s been lost.*

To support the body’s ability to rebuild solid, strong bones, your body need to maintain the right balance of all the nutrients needed to complete the remodeling process. So, regular intake of those nutrients is vital for a steady supply.*

You need plenty of calcium, magnesium, vitamin D, and vitamin K. Regular use of USANA’s Vitamin K2 supplement will help supply plenty of this essential nutrient to help ensure calcium goes where it’s needed to form and maintain strong, resilient bones.*

Here’s how it works.

A number of proteins that support proper bone remodeling are dependent on vitamin K2. One of the main proteins is osteocalcin, which helps establish a matrix, or organizing structure, for bone.

Initially, osteocalcin is released by vitamin D3. But it requires vitamin K2 to be activated. (This is why it’s also important to get enough dietary vitamin K2 if you supplement vitamin D.) The activation process is critical, because it makes the calcium “stick” to and be incorporated into the bone.*

That’s not the only way vitamin K2 offers bone-supporting benefits. It also helps turn some genes on or off that regulate bone remodeling. This action helps keep the resorption process balanced—so, ideally, your body won’t break down and absorb more bone than is replaced.*

Constantly maintaining that balance is important at any age to help preserve healthy bone density. But it becomes a bigger concern for women as they age. After menopause, women tend to lose more bone density as a result of the changes in hormone levels. Vitamin K2 may be able to help offset some (but not all) of that bone loss over time.*

A three-year study looked at the effects when healthy postmenopausal women consumed 180 mcg of the MK-7 form of vitamin K2 daily. Results showed that supplementation significantly improved vitamin K status and better maintained bone density in the spine and neck (changes weren’t seen in the hip). Healthy bone strength was also retained.*

On the other hand, another study found that women over 70 who had high levels of osteocalcin that hadn’t been activated by vitamin K2 (called undercarboxylated osteocalcin) were less likely to maintain healthy bone density. This illustrates the importance of vitamin K2 to maintaining your skeletal stability as you age.*

Building up your bone strength is important for staying active throughout your lifetime. If you don’t have enough vitamin K2 in your body, calcium won’t deposit into your bone as efficiently to retain healthy bone density. So, supplementing your vitamin K2 can help maintain strong bones, when used as part of a healthy lifestyle.*

Vitamin K2 may also benefit your oral health to help keep you smiling. By maintaining proper bone balance, USANA’s Vitamin K2 supports the health of your jaw and teeth.*

The bone-building benefits of Vitamin K2 are even greater when you also supplement calcium along with other important bone minerals. That makes Vitamin K2 an excellent companion to USANA MagneCal D and/or Vitamin D.*

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Vitamin K2 Keeps Calcium Where It Belongs to Protect Cardiovascular Health

As mentioned above, adequate vitamin K2 in your body helps usher calcium into the bones, where it’s needed. If the calcium doesn’t end up in your bones, it still has to go somewhere. So, it could end up in soft tissues and make them more rigid.*

USANA Vitamin K2 helps maintain flexible arteries and normal cardiovascular function. It does this by supporting your body’s natural mechanism for directing calcium to the right place, at the right time.*

Vitamin K2 as MK-7 supports vascular health by activating another protein, called matrix Gla. This protein is found in soft tissues, including the heart, blood vessel walls, and cartilage. It binds to calcium to stop it from being incorporated into your soft tissues.*

This makes USANA Vitamin K2 important for more than bone health. It offers significant support for maintaining healthy cardiovascular function by supporting your body’s natural ability to keep your heart and blood vessels healthy and flexible.*

If maintaining good circulation is at the heart of your healthy lifestyle, USANA Vitamin K2 is a great addition to your supplement routine. And it pairs perfectly with Proflavanol C to help keep your blood flowing.*

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Key Ingredients

  • Vitamin K2 (MK-7)

See full list of ingredients

Usage

Take one (1) tablet daily, preferably with food.

Ideal For

  • Healthy adults
  • Postmenopausal women
  • Adults taking calcium or vitamin D supplements

Frequently Asked Questions About Vitamin K2

Anyone currently taking blood-thinning medications should discuss the use of vitamin K-containing supplements (including the CellSentials, HealthPak, Vitamin D, and Vitamin K2) with their physician.

Vitamin K2 is a sensitive ingredient that can degrade and lose potency quickly when included in formulas along with other nutrients. While USANA uses one of the most stable forms of vitamin K2 available, we’ve opted to offer it as a stand-alone product at this time. This is to ensure you get the highest quality product possible, with a dosage in the tablet that you can trust will match what is on the label.

Keeping Vitamin K2 as a separate product also allows people who are taking blood thinning medications—and therefore must carefully monitor vitamin K intake—to get the important benefits of MagneCal D without concern.

Vitamin K1 and vitamin K2 come from different sources and perform different actions in your body. Vitamin K1 is found in leafy green vegetables. Its primary function in the body is to act as a coenzyme that is necessary for healthy blood clotting. Vitamin K2 is found in certain types of meat, dairy, eggs, and fermented foods like natto. Vitamin K2 is also produced, to a lesser extent, by intestinal microbes. Its primary function within the body is related to supporting cardiovascular and bone health.*

The primary function of vitamin K2 is to support the body’s natural process of directing calcium deposition. Simply stated, it helps maintain healthy blood vessels and a strong skeleton by directing calcium into bones and teeth.*

Recent studies have shown that many people do not consume enough vitamin K2  in their diet to reach optimal levels. A supplement is a convenient way to achieve higher levels in the body to get full nutritional support.

Each tablet of USANA Vitamin K2 contains 180mcg. The suggested adult dose is one tablet per day.

USANA Vitamin K2 is labeled for adult use. It is important to consult your child’s physician to determine appropriate use. This tablet can be a choking hazard for children who have difficulty swallowing tablets.

You should always consult your physician or pharmacist to check for interactions with dietary supplements and medications. Special consideration should be taken if you are taking anticoagulation medications.

You should always  consult your physician before using any dietary supplements while pregnant.

USANA Vitamin K2 is made with high potency MK-7. MK-7 is absorbed well by the body and remains active longer than the other form—MK-4. However, it can be converted to MK-4 in the body as needed.*

A lower amount is included in USANA Vita Antioxidant, along with vitamin K1, for broad nutritional support. It is also found in USANA Vitamin D. For additional support for bone and cardiovascular health, or if you use USANA MagneCal D, you may want to add Vitamin K2 to your supplement routine. There is no upper limit for vitamin K, and the products are designed to work together.

There are a number of USANA products that will pair well with the Vitamin K2 supplement to support overall health, as well help maintain your bones and cardiovascular system:*

  • USANA CellSentialsTM delivers a broad-spectrum nutritional foundation for your overall well-being*
  • MagneCal D™ provides the other nutrients needed to support bone health*
  • Procosa® helps maintain bone and joint function*
  • Proflavanol® C100 helps support cardiovascular health*
  • CoQuinone® 30 helps maintain a strong heart*

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471136/

https://www.ncbi.nlm.nih.gov/pubmed/23525894

https://www.ncbi.nlm.nih.gov/pubmed/15514282

https://www.ncbi.nlm.nih.gov/pubmed/19179058

https://www.ncbi.nlm.nih.gov/pubmed/28646812

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494092/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040265/

https://www.ncbi.nlm.nih.gov/pubmed/8739908?dopt=Abstract

https://www.ncbi.nlm.nih.gov/pubmed/16801507

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

https://www.ncbi.nlm.nih.gov/pubmed/29749440

https://www.ncbi.nlm.nih.gov/pubmed/25516361

https://www.ncbi.nlm.nih.gov/pubmed/18722618

https://lpi.oregonstate.edu/mic/vitamins/vitamin-K

https://www.healthline.com/nutrition/vitamin-k2#sources

https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/

https://www.ncbi.nlm.nih.gov/pubmed/24296867

https://www.ncbi.nlm.nih.gov/pubmed/30791399

K2Vital Delta: Market Study 2016. Kappa Bioscience.

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true health assessment

Health comes as a result of choosing a healthy lifestyle every day. That includes moderate exercise, ample water, plenty of restful sleep, and a balanced diet full of fruits and vegetables.

Stress, poor diet, inactivity, and environmental pollutants can all take a toll on your health. The ever-growing burden on your body is why it is so important to get all the nutrients you need. And you need to get them in the right amounts to protect your most valuable asset—your health.

Even the healthiest diets usually fail to provide the right amounts of nutrients needed to achieve and maintain optimal health.* So, high-quality nutritional supplements should be a key component of a healthy lifestyle, too. But the question remains: Which supplements should I take?

Take this product advisor quiz to find out which USANA supplements are right for you.

 

Proflavanol® C100 contains grape-seed extract and vitamin C to deliver powerful support for cardiovascular, immune, skin health, and more.*

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BiOmega™ features purified fish oil with omega-3 fatty acids and an extra dose of vitamin D. These ingredients help support nearly every cellular function in your body, including healthy brain and cardiovascular function.*

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USANA Probiotic contains a blend of good bacteria that helps support healthy digestion, nutrient absorption, and normal immune function.*

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Procosa® is a joint-health formula made with USANA InCelligence Technology. It contains glucosamine and Meriva bioavailable curcumin to help promote the formation of healthy cartilage and support your joints’ mobility at any age.*

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CoQuinone® 30 contains coenzyme Q10 and alpha-lipoic acid, two critical nutrients needed for generating the energy to power your cells. This powerful formula keeps you healthy and energized throughout the day.*

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Hepasil DTX™ uses USANA InCelligence Technology, a powerful antioxidant blend, to combat oxidative stress in a healthy liver. And it helps support your body’s natural detoxification processes.*

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MagneCal D™ contains magnesium and calcium, plus vitamin D, to support bone health, muscle function, and energy metabolism so you can keep moving.*

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Visionex® contains a unique antioxidant blend that includes lutein. It helps protect the delicate tissues of your retina and supports long-term eye health.*

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USANA Digestive Enzyme contains carefully selected enzymes that help to breakdown carbohydrates, fats, proteins, and lactose. This helps give you the digestive support you need to avoid feeling uncomfortable and bloated after eating.*

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EstroPro™ is a phytoestrogen supplement that helps relieve many common symptoms of menopause, including hot flashes, night sweats, mood swings, sleeplessness, and fatigue. It also helps maintain bone and cardiovascular health.

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USANA Vitamin D is a combination of advanced levels of vitamin D3 and vitamin K2 to support healthy bones and cellular health.*

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Pure Rest™ is a fast-acting melatonin supplement designed to help you get to sleep and give your body the quality rest it needs so you can function at your best.*

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Palmetto Plus™ contains a combination of saw palmetto, soy isoflavones, and lycopene designed to support healthy prostate function for men at any age.*

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CopaPrime+™ is a brain-support supplement that helps power peak mental performance. It supports learning, focus, and memory with a unique blend of nootropics: American ginseng plus bacopa and coffee-seed extract in the InCelligence Cognitive-Support Complex.

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Proglucamune® includes USANA InCelligence Technology in a powerful combination of zinc and exclusive Beta-Glucan Complex. It supports healthy immune defense during times of occasional stress.*

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BOOSTER C 600 is a delicious lemon-berry drink mix that contains USANA’s Poly C® blend. You’ll also get other potent, immune-supporting ingredients to keep you feeling healthy when you need an occasional boost.*

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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Reveal Your Youthful Radiance with Celavive® Hydrating + Lifting Sheet Mask

Celavive® Hydrating + Lifting Sheet Mask

Lift, hydrate, and rejuvenate skin’s appearance with a concentrated serum of the Celavive® Cell Signaling Complex and some of nature’s best botanicals.

Get glowing in only 20 minutes with Celavive® Hydrating + Lifting Sheet Mask. Infused with USANA InCelligence Technology™, this replenishing facial treatment will help reveal more radiant, youthful-looking skin in just one application.

Each sheet mask delivers concentrated rejuvenating ingredients that penetrate deep within your skin. Use morning or night, after Perfecting Toner, a few times a week—or anytime you want visible results:

  • Skin looks tighter and lifted
  • Moisture is replenished
  • Complexion appears smooth and bright

After you remove your Hydrating + Lifting Sheet Mask, massage the remaining serum into your skin. The active ingredients will keep working to help reveal your youthful radiance. The powerful peptides and potent botanicals combine innovative science with some of the most popular ingredients in Korean and Japanese skincare.

Hydrating + Lifting Sheet Mask can be used with either the oily/combination or dry/sensitive Celavive regimen. And you can feel good knowing that each cotton mask is saturated with a serum made without parabens or alcohol.

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Decrease the Look of Fine Lines and Wrinkles with Celavive Hydrating + Lifting Sheet Mask

You have a new secret weapon in your fight to reduce the visible signs of aging—the Celavive Hydrating + Lifting Sheet Mask. Each sheet delivers an intense boost of the Celavive® Cell Signaling Complex. And the ratio of ingredients in the complex have been adjusted to deliver more noticeable results.

The sheet mask helps smooth the appearance of fine lines and wrinkles by using the most highly concentrated amount of Palmitoyl Tripeptide-38 available in any Celavive product. This beauty peptide mimics those found naturally in structural proteins within your epidermis—collagen and laminin—to create a plumper, younger-looking complexion.*

Palmitoyl Tripeptide-38 supports natural processes in your skin cells that will help give your skin a firmer look. You will notice that skin looks tighter. And the appearance of crow’s feet and forehead lines will be diminished.

You will also feel a tightening effect thanks to an ingredient in the sheet mask called pullulan. It’s a natural, water-soluble polysaccharide (sugar) produced by fermenting Aureobasidium pullulans—a black, yeast-like fungus. (That may sound scary, but it’s totally not.) The pullulan helps form a thin layer of serum. This allows the active ingredients to work on the epidermis, so skin appears supple and smooth when the hydrating mask is removed.

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Protect, Soothe, and Rejuvenate with Moisturizing Extracts

Reveal your skin’s natural radiance as you replenish your complexion with the botanical extracts in Celavive Hydrating + Lifting Sheet Mask. Many of the extracts will help revive your appearance. And they are gentle on your skin.

The following extracts are blended with two ingredients that help trap moisture in the skin (1,2 Hexanediol and butylene glycol). By combining these plant extracts with moisture, you will get a boost in hydration.

Brown algae (Ascophyllum nodosum), or knotted wrack, is a nutrient-rich seaweed found along the coasts of the northern Atlantic Ocean. It restores your radiance with minerals and antioxidants. It can also help your skin naturally detoxify as it nourishes for a healthy appearance.

Fireweed extract (Epilobium angustifolium) comes from the flowers, leaves, and stems of the Rose Bay (an herb plant). It brightens your complexion as it balances hydration. And the polyphenols (a type of antioxidant) from this extract may help minimize the visible effects of stress.

Purslane (Portulaca oleracea) calms as it delivers nutrients, fatty acids, and antioxidants, including vitamins C and E. The antioxidants help protect skin from oxidative damage, helping to preserve a firmer look.

In addition to the nourishing extracts, skin conditioners in Hydrating + Lifting Sheet Mask also moisturize to help skin look plumper. This includes sodium hyaluronate—the salt form of hyaluronic acid. Cyclopentasiloxane and cyclohexasiloxane are also conditioning agents.

Refresh Your Complexion with Multifunctional Botanicals

The Celavive Hydrating + Lifting Sheet Mask is packed with multitasking skincare ingredients. These botanical extracts offer a multitude of benefits for your complexion.

  • Japanese honeysuckle (Lonicera japonica) imparts a light fragrance as it soothes and conditions the skin for a smooth, hydrated appearance.
  • Japanese pepper (Zanthoxylum piperitum) energizes skin and provides protective antioxidant activity for a healthy complexion.
  • Grapefruit (Citrus paradisi) contains vitamin C and is rich in phenolic compounds (chemicals that come from plants), including gallic acid. Vitamin C and gallic acid both offer antioxidant activity to promote an even, bright appearance.
  • The fragrant extract of Chinese star anise (Illicium verum) protects your natural radiance with antioxidants that help neutralize free radical damage.
  • Baikal skullcap (Scutellaria baicalensis) is a soothing, purifying herb. It helps defend against oxidative stress and preserve the appearance of an even skin tone. It also supports a healthy skin barrier for a more youthful look.

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Key Ingredients

See full list of ingredients
See glossary of Celavive Ingredients

Usage

Remove mask from foil packaging and gently unfold before applying it to a clean, dry face. Remove mask after 20 minutes and massage any excess product into skin in upward and outward motions.

Caution: Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children

Frequently Asked Questions about Celavive Hydrating + Lifting Sheet Mask

Agregán R, et al. 2018. Antioxidant Potential of Extracts Obtained from Macro- (Ascophyllum nodosum, Fucus vesiculosus and Bifurcaria bifurcata) and Micro-Algae (Chlorella vulgaris and Spirulina platensis) Assisted by Ultrasound. Medicines (Basel) 5(2).

Ruszová E, et al. 2013. Epilobium angustifolium extract demonstrates multiple effects on dermal fibroblasts in vitro and skin photo-protection in vivo. Gen Physiol Biophys 32(3): 347-59.

Schepetikin A, et al. 2016. Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed). Phyto Res 30(8): 1287-1297.

Baumann L. 2015. Portulaca oleracea (purslane). Derm News [Internet] [accessed 25 April 2018] Available at https://www.mdedge.com/edermatologynews/article/99635/aesthetic-dermatology/portulaca-oleracea-purslane

Kim I, Lee M, Shim S, Chun Y. 2013. Skin Lightening and Wrinkle Improving Efficacy of Organic Portulaca oleracea Extract in Skin Care Cosmetic. Int Jour BioSci BioTec 5(5): 75-84.

Johnson W Jr, et al. 2011. Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane. Int J Toxicol 30(6 Suppl): 149S-227S.

Yamazaki E, Inagaki M, Kurita O, Inoue T. 2007. Antioxidant activity of Japanese pepper (Zanthoxylum piperitum DC.) fruit. Food Chem 100(1): 171-177.

Cavinato M, et al. 2017. Plant extracts and natural compounds used against UVB-induced photoaging. Biogerontol 18(4): 499-516.

Su T, et al. 2013. Inhibition of Melanogenesis by Gallic Acid: Possible Involvement of the PI3K/Akt, MEK/ERK and Wnt/β-Catenin Signaling Pathways in B16F10 Cells. Int J Mol Sci 14(10): 20443-20458.

Baier, A, et al. 2015. Inhibition of advanced glycation end products in skin aging – a new target for Citrus paradisi. [Internet] [accessed 25 April 2018] Available at http://tst.pg2.at/abstracts/a0334.html?zoom_highlight=

Xiu-ling Z. Research progress in natural active components of Illicium verum Hook.f. Sci Tech Food Ind [Internet] [accessed 27 April 2018] Available at http://en.cnki.com.cn/Article_en/CJFDTOTAL-SPKJ201219083.htm

Jiang L. 2015. Review: Cosmeceutical Potential of Chinese Skullcap (Scutellaria Baicalensis). Glob Jour Res Anal 4(7): 132-133.

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