Celavive Vitalizing Serum

Reveal firm, glowing skin with a concentrated blend of nutrients that includes USANA proprietary BioPeptide-CS.

Reveal Firm, Glowing Skin with Celavive Vitalizing Serum

Dramatically reduce the appearance of fine lines and wrinkles and reveal your youthful radiance with Celavive Vitalizing Serum. Applied after Perfecting Toner or Hydrating + Lifting Sheet Mask, this water-based serum delivers targeted active ingredients and supports your skin’s natural renewal processes.

Celavive Vitalizing Serum includes a highly concentrated amount of the unique peptides and botanicals in BioPeptide-CS. The formula is also packed with nutrients and supports antioxidants that help condition and replenish skin.

Celavive Vitalizing Serum begins to visibly transform the look of your skin. From the first application, you’ll see:

  • Increased firmness
  • Visibly reduced fine lines and wrinkles
  • Smooth, supple look and feel
  • Minimized appearance of pores
  • Brighter, even skin tone with reduced appearance of hyperpigmentation

Celavive Vitalizing Serum is also clinically studied to improve:

  • The appearance of wrinkles by 12%
  • Visible fine lines by 24%
  • Firm-looking skin by 6%
  • Smoothness by 16%

Made without parabens, Celavive Vitalizing Serum is safe for dry, oily, sensitive, and combination skin.

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Softens the Look of Fine Lines and Wrinkles

You may not be able to turn back the clock, but Celavive Vitalizing Serum helps refresh and revitalize the look of your skin for a more youthful appearance.

Get powerful support for your visibly stressed skin caused by environmental and lifestyle factors with BioPeptide-CS. The botanical extracts and peptides work together to promote firm, vibrant-looking skin. The complex features InCelligence Technology, designed to support the skin’s natural processes for a visibly smoother complexion.

There are a number of ways the complex promotes the look of healthy skin:

  • Helps rebalance the look of stressed skin for a smoother appearance
  • Supports the skin’s moisture barrier to promote plump, hydrated-looking skin
  • Retains building blocks of healthy skin, including collagen, elastin, and hyaluronic acid, to fight the visible signs of aging and maintain firmness
  • Provides antioxidant support to promote a brighter, more even-looking skin tone

Supporting these processes within your skin can significantly reduce the appearance of fine lines and wrinkles and improve your overall complexion.

Healthy Collagen Helps Skin Look Tighter and Firmer

Youthful-acting skin is supple and resilient. Its strength comes from the ability to act a bit like a rubber band. It bounces back after stretching. The visible effects of less elasticity are gradual sagging and increased fragility of the skin.

Maintain your skin’s youthful firmness by supporting strong collagen and elastin in your skin matrix. Collagen is vulnerable after sun exposure because the free radicals and dryness created can cause it to break down. If too much collagen is degraded, you will see wrinkles and less elasticity in the skin.

BioPeptide-CS in Celavive Vitalizing Serum targets key cellular processes that support collagen and other structural proteins from breaking down to help minimize the appearance of fine lines and wrinkles.

Similarly, Celavive Vitalizing Serum is formulated to visibly improve the look of skin affected by environmental stressors, including those associated with advanced glycation end products (AGEs). AGEs are destructive molecules formed in reactions between sugars and proteins, lipids, or nucleic acids. These molecules can cause collagen to become rigid and more prone to breakage.

Collagen weakened by AGEs can cause skin to look thin, discolored, and slack. Oxidative stress can speed this process, especially from a diet full of fried foods and refined sugars. Inhibiting some of the effects of AGEs with antioxidants helps shield healthy collagen, preserving skin’s elasticity.

Celavive Vitalizing Serum contains a Superfood Complex made with fungi extract that contains a blend of adaptogens and antioxidants to support collagen and elasticity. Vitalizing Serum is designed to visibly enhance skin’s elasticity for a firmer, more supple appearance after use. A private study showed skin elasticity improved in three hours, meaning you’ll see visibly firmer skin.

Lipids and Skin Cells Are Protected

Protecting skin cells and natural lipids from damage helps preserve skin’s elasticity and firmness. One way to protect against damage and prevent early signs of aging is through the use of antioxidants.

The concentrated BioPeptide-CS in Vitalizing Serum supports the skin’s defense against oxidative stress and nurtures the moisture barrier for a healthy, hydrated appearance. This visible brightening action is boosted by many additional protective antioxidants in Vitalizing Serum, including coenzyme Q10 (ubiquinone) and Olivol24.

Coenzyme Q10 provides antioxidant support and helps reduce the appearance of fine lines and wrinkles. It also supports a firmer, more youthful-looking complexion.

Olivol24, USANA’s proprietary blend derived from olive fruit extract, delivers 24 hours of hydration to promote a luminous, healthy-looking complexion. These two ingredients work together to visibly brighten and smooth the skin’s surface—revealing a complexion that looks vibrant and healthy.

Youthful Skin Appearance and Tone is Preserved

Melanin plays a protective role in the skin. However, when too much is produced in one area, you can see age spots, freckles, or uneven coloration. While shifts in melanin are usually normal, they can dull your natural glow and affect your confidence.

The encapsulated liposomal bakuchiol in Vitalizing Serum promotes a youthful-looking complexion. This plant-based is delivered through lipid vesicles to enhance absorption and promote visible skin benefits.  It supports balanced melanin production and visibly even skin tone—all with a gentler touch than traditional retinoids.

Note: Always make sure you have any questionable spots or freckles inspected by your dermatologist.

Clinical Studies

An eight-week study was conducted to evaluate the efficacy of Celavive Triple Action Eye Cream on the appearance of the skin around the eyes. The study included 36 women between the ages of 35 and 75, representing diverse racial backgrounds and a range of skin types, including combination, dry, and normal. Participants presented with mild to moderate under-eye puffiness, dark circles, fine lines, wrinkles, and a lack of firmness or radiance.

Subjects were instructed to apply the test material twice daily as directed to the skin around the eyes, between the brows, the marionette lines, nasolabial folds, cheeks, and jawline. The first application was performed in the clinic immediately following baseline assessments. Product use continued for eight weeks, with measurements taken at baseline, week 2, week 4, and week 8 to assess improvements in skin appearance.

Results show that under the conditions of the test, Vitalizing Serum demonstrated a noticeable improvement in the appearance of fine lines— nearly 25% around the eye area, close to 20% on the forehead, and more than 15% across the upper lip and chin area.

This graph shows the results at week 8 of the study. Subjects saw an improvement in skin smoothness, particularly in the eye area, forehead, chin area, upper lip, and cheeks.

% Improvement From Baseline to Week 8

Nutrients Are Restored to Nourish Skin Cells

If your skin is stressed, it may be low on crucial nutrients it needs to keep looking healthy. Support your skin’s natural glow with Celavive Vitalizing Serum. The extract used in the formula is deeply penetrating for maximum benefit to the look and feel of your skin.

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Key Ingredients

See full list of ingredients
See glossary of Celavive Ingredients

Usage

Directions: After applying toner, apply 2–3 pumps of product evenly across face and neck, in upward and outward motions.

Caution:  Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs.

Ideal For

  • All skin types

Frequently Asked Questions About Celavive Vitalizing Serum

Please submit questions below.

  1. Briggaman A, Wheeler C. The epidermal-dermal junction. Journal of Investigative Dermatology 65.1 (1975): 71-84. Web. 08 June 2017.
  2. Gemede H. “Nutritional quality and health benefits of okra (Abelmoschus esculentus): a review.” Journal of food processing and technology 06.06 (2015): n. Pag. Web. 9 June 2017.
  3. Aburjai T, Natsheh F. “Plants used in cosmetics.” Phytotherapy Research 17.9 (2003): 987-1000. Web. 009 June 2017.
  4. Draelos ZD.  Cutis 81.1 (2008): 87-89. Web. 09 June 2017.
  5. Mylonas C, Kouretas D. 1999. Lipid peroxidation and tissue damage. In Vivo 13(3): 295-309. https://www.ncbi.nlm.nih.gov/pubmed/10459507
  6. Jadoon S, et al. 2015. Ox Med Cell Long 709628: 17 pages [page numbers not noted]. https://www.hindawi.com/journals/omcl/2015/709628/abs/
  7. Nassiri-Asl M, Hosseinzadeh H. 2016. Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update. Phytoth Res 30(9): 1392-1403. http://onlinelibrary.wiley.com/doi/10.1002/ptr.5644/full
  8. Baumann LS. Less-known botanical cosmeceuticals. Dermatologic Therapy. 2007;20(5):330–342. https://www.ncbi.nlm.nih.gov/pubmed/18045358
  9. Pownali T, Udenigwe C, Aluko R. 2010. Amino Acid Composition and Antioxidant Properties of Pea Seed (Pisum sativum L.) Enzymatic Protein Hydrolysate Fractions. J Agric Food Chem 58(8): 4712-4718. http://pubs.acs.org/doi/abs/10.1021/jf904456r
  10. Pittayapruek P, et al. 2016. Role of Matrix Metalloproteinases in Photoaging. Int J Mol Sci 17(6): 868. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926402/
  11. Meissner M, et al. 2011. AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes. Exp Derm 20(5): 425-429. http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2011.01253.x/full
  12. Pérez-Sánchez A, et al. 2016. J Dermatol Sci 84(2): 169-177. https://www.ncbi.nlm.nih.gov/pubmed/27528586
  13. Miroliaei M, Khazaei S, Moshkelgosha S, Shirvani M. 2011. Inhibitory effects of Lemon balm (Melissa officinalis, L.) extract on the formation of advanced glycation end products. Food Chem 129(2): 267-271. http://www.sciencedirect.com/science/article/pii/S0308814611005887
  14. Jariapamornkoon N, Yibchok-anun S, Adisakwattana S. 2013. Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity. BMC Complement Altern Med 13: 171. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716656/
  15. Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis. Bioorg Med Chem Lett 27(15): 3374-3377. https://www.ncbi.nlm.nih.gov/pubmed/28619537
  16. Chang T. 2009. An Updated Review of Tyrosinase Inhibitors. Int J Mol Sci 10(6): 2440-2475. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705500/
  17. Binic I, et al. 2013. Skin Ageing: Natural Weapons and Strategies. Evid Based Complement Alternat Med 2013: 827248. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569896/#B29
  18. Farris P. 2015. Dermatology Times. Resveratrol, the longevity molecule [Internet] [accessed 12 Dec 2017] Available at http://dermatologytimes.modernmedicine.com/dermatology-times/news/resveratrol-longevity-molecule?page=full
  19. Shi J, Yu J, Pohorly JE, Kakuda Y. 2003. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6(4): 291-9. https://www.ncbi.nlm.nih.gov/pubmed/14977436
  20. Zi SX, et al. 2009. Oligomeric proanthocyanidins from grape seeds effectively inhibit ultraviolet-induced melanogenesis of human melanocytes in vitro. Int J Mol Med 23(2): 197-204. https://www.ncbi.nlm.nih.gov/pubmed/19148543
  21. Cornaghi L, et al. Effects of UV Rays and Thymol/Thymus vulgaris L. Extract in an ex vivo Human Skin Model: Morphological and Genotoxicological Assessment. Cells Tissues Organs 201(3): 180-192.  https://www.karger.com/Article/Abstract/444361
  22. Calò R, Visone C, Marabni L. Thymol and Thymus Vulgaris L. activity against UVA- and UVB-induced damage in NCTC 2544 cell line. Mut Res/Gen Tox Env Mut 791: 30-37. http://www.sciencedirect.com/science/article/pii/S1383571815001990
  23. Velijkovic I. The Dermatologist. Mitochondria and the Skin [Internet] [accessed 13 Dec 2017] Available at https://www.the-dermatologist.com/content/mitochondria-and-skin
  24. Zielinska A, Nowak I. 2017. Abundance of active ingredients in sea-buckthorn oil. Lip Health Dis 16: 95. https://lipidworld.biomedcentral.com/articles/10.1186/s12944-017-0469-7
  25. Telang P. 2013. Vitamin C in dermatology. Indian Dermatol Online 4(2): 143-146. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673383/

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Celavive Contouring Face & Neck Cream

Lift, firm, contour, and smooth skin with formulas that feature exclusive Celavive skincare technologies.

Restore Radiant Skin with Celavive Contouring Face & Neck Cream

Reveal visibly younger-looking skin with Celavive Contouring Face & Neck Cream. Diminish the appearance of visible signs of your skin’s aging through restored moisture, creating the radiant, youthful look you want.

Whether you have sensitive, combination, dry, or oily skin, it needs to be nourished with intense moisture. You’ll get that when you include Contouring Face & Neck Cream in your Celavive skincare regimen.

Your skin will shine with these visible benefits:

  • Replenished hydration
  • Reduced visible signs of aging
  • Minimized appearance of fine lines and wrinkles

Celavive Contouring Face & Neck Cream is also clinically studied to improve:

  • Firmer-looking skin around the eye area by 11%
  • Visible elasticity around the eye area by 10%
  • The appearance of overall radiance by 18%

Celavive Contouring Face & Neck Cream is made from quality ingredients to restore your skin’s hydration, radiance, and youthful look and texture. You’ll visibly reduce the signs of aging by minimizing the appearance of fine lines and wrinkles.

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Restored Radiance is Possible with Celavive Contouring Face & Neck Cream

If you’ve had a long day, think about what your skin’s been through. Your largest organ does many jobs—protection and regulation for a start. And it’s supposed to look good doing them.

Treat your hard-working skin to luxurious moisture with Celavive Contouring Face & Neck Cream. The advanced active ingredients work to support your complexion. That way, your skin stays strong and looks youthful and radiant.

It all starts with BioPeptide-CS. USANA InCelligence Technology is utilized in Face & Neck cream to support visible skin vitality and promote a healthy-looking complexion. The complex includes ingredients like southernwood extract, coffee seed extract, hexapeptide-48 HCl, and palmitoyl tripeptide-38. These compounds work to enhance the appearance of the skin by supporting the natural functions associated with maintaining a youthful and radiant look.

For example, Hexapeptide-48 HCl supports the skin’s barrier function to create a smooth-looking skin surface overnight. Maintaining a healthy skin barrier contributes to the appearance of resilient, healthy-looking skin over time. A strong and thick skin barrier amplifies moisture retention for a visibly soft and youthful complexion.

Southernwood (Artemisia abrotanum) extract can support your skin’s lipids and protect collagen and elastin from breaking down to help maintain a youthful appearance. This compound is rich in oligosaccharides (complex sugars) that work to make the skin appear smooth and luminous.

Experience Intense Hydration

Celavive Contouring Face & Neck Cream is formulated to provide intense hydration. Dry skin is tight, rough, and can look wrinkled. Moisture changes all of that. That’s why the moisturizing ingredients help support exceptional hydration that smooths and plumps the look of skin for a youthful appearance.

Olivol24 adds deep hydration and helps balance your skin’s natural moisturizing factors. The fruit extracts in the botanical blend have been clinically shown to provide 24 hours of rich hydration after just one application.

Plum extract helps reduce the appearance of aging and delivers immediate hydration. Like many fruits, plums contain natural sugars and organic acids that are natural humectants—water-loving substances that can attract and bind water molecules from the surrounding environment. The humectants in plum extract prevent this water from evaporating from the skin’s surface, increasing your skin’s water content.

Hydration is key to healthy skin. When skin cells are hydrated, they swell. This “plumping” effect fills out the spaces between cells, reducing the visibility of fine lines and wrinkles. Similarly, hydrated skin is more pliable and resilient, affecting its ability to stretch and return to its original shape. The hydrating ingredients in Celavive Contouring Face & Neck Cream can help reinforce the skin’s moisture barrier to lock in hydration and promote a smoother, firmer appearance.

Reduce the Appearance of Fine Lines and Wrinkles

Superfood complex helps visibly smooth the skin’s surface and reduce the appearance of fine lines and wrinkles through a blend of adaptogens to support the skin’s moisture barrier.

Adaptogens support the skin’s natural balance. They are believed to help skin “adapt” to help improve the look of skin exposed to daily stressors, promoting a balanced and resilient appearance. This can lead to a more even skin tone, improved texture, and a healthier-looking complexion over time.

In addition to their balancing effects, adaptogens also contribute to strengthening the skin’s natural moisture barrier. A fortified barrier helps retain hydration, which contributes to the look of smooth, supple, and elastic skin.

The Superfood complex in Contouring Face & Neck Cream is also rich in antioxidants to help minimize the visible effects of oxidative stress and support the appearance of firm, smooth skin. As a result, the skin’s surface looks lifted and more refined.

An Approach to Youthful-Looking Skin

With the Contouring Face & Neck Cream, you’ll get a powerful formula that supports the appearance of visibly younger-looking skin. Engelhardtia chrysolepis (leaf) extract has been clinically studied for its potential to support the appearance of firm, elastic skin and reduce visible signs of aging associated with glycation.

Glycation is a natural process where sugar molecules—like glucose or fructose—bind to proteins such as collagen and elastin. This leads to the formation of Advanced Glycation End Products (AGEs), which can stiffen and weaken these structural proteins. Over time, AGEs contribute to visible signs of aging, including loss of firmness, fine lines, and dullness. By addressing visible signs of glycation, the cream helps promote a smoother, more resilient, and radiant-looking complexion.

Radiant, Youthful-Looking Skin

Refresh your skin with Celavive Contouring Face & Neck Cream. This product’s advanced combinations of powerful active ingredients will provide intense hydration for visibly younger-looking skin.

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Clinical Study

An eight-week study was conducted to evaluate the efficacy of Celavive Contouring Face & Neck Cream on the appearance of the skin in the face and neck. The study included 34 women between the ages of 40 and 70, representing diverse racial backgrounds and a range of skin types, including combination, dry, and normal. Participants presented with mild to moderate lines on the neck, marionette wrinkles, lack of visual firmness, and lack of radiance.

Subjects were instructed to apply the test material twice daily as directed to the entire face and neck. The first application was performed in the clinic immediately following baseline assessments. Product use continued for eight weeks, with measurements taken at baseline, week 2, week 4, and week 8 to assess improvements in skin appearance.

Results show that under the conditions of the test, Contouring Face & Neck Cream demonstrated a noticeable improvement in the appearance of radiance, firmness, and elasticity.

This graph shows the results at week 8 of the study. Subjects saw improvements in the appearance of skin radiance, firmness, and elasticity, particularly in the eye area.

Key Ingredients

See full list of ingredients

See glossary of Celavive Ingredients

Usage

Start with clean skin by washing your Face & Neck. Dispense on pump of the cream and apply it to your Face & Neck. Using upward, circular motions, gently massage the cream into your skin. For best results, apply the cream both AM and PM as part of your skincare routine.

Caution: Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.

Ideal For

  • All skin types

Frequently Asked Questions about Celavive Contouring Face and Neck Cream

Li, Yi-Chen, Chi-Ruei Chen, and Tai-Horng Young. “Pearl extract enhances the migratory ability of fibroblasts in a wound healing model.” Pharmaceutical Biology 51.3 (2012): 289-97. Web. 09 June 2017.

Rabouille, Thierry. Skin moisturizing compositions. Galderma Research and Development, assignee. Patent 8758805. 24 June 2014. Print.

“Macadamia Oil” Wikipedia. Wikimedia Foundation, 06 Apr. 2017. Web. 12 June 2017.

Deckard, Angela. “8 Benefits of gardenia essential oil.” Healthy Focus. healthyfocus.org. 20 June 2016. Web. 18 June 2017.

Chajra, H., B. Amstutz, K. Schweikert, D. Auriol, G. Redziniak, and F. Lefevre. “Opioid receptor delta as a globular modulator of skin differentiation and barrier function repair.” International Journal of Cosmetic Science 37.4 (2015): 386-94. Web. 16 June 2017.

Schmidt, Alfred, and Heinrich Weiland. Cosmetic or cosmetic product for firming and smoothing skin, in particular in the case of cellulite. S.W. Patentverwertungs Ges. M.B.H., assignee. Patent 5945109. 31 Aug. 1999. Print.

Cheng, Wai. “The relationship between peroxisome proliferator-activated receptors (PPAR) and cell proliferation.” American Journal of Clinical Dermatology. 9.1 (2008): 15-31. Springer Link. Web. 19 June 2017.

Lupo, Mary P., and Anna L. Cole. “Cosmeceutical peptides.” Dermatological Therapy 20.5 (2007): 343-49. Web. 19 June 2017.

Pazyar, N; Yaghoobi, R; Ghassemi, MR; Kazerouni, A; Rafeie, E; Jamshydian N. “Jojoba in dermatology: a succinct review.” G Ital Dermatol Venereol. 2013 Dec;148(6):687-91.

Meyer, J; Marshall, B; Gacula, M Jr.; Rheins, L. “Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study.” J Cosmet Dermatol. 2008 Dec;7(4):268-74.

Sethi, Anisha; Kaur, Tejinder; Malhorta, SK; Gambhir, ML. “Moisturizers: The Slippery Road.” Indian J Dermatol. 2016 May-Jun; 61(3): 279–287.

http://www.duponttateandlyle.com/sites/default/files/Skin%20Care%20Brochure%2010.11.17_0.pdf

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Celavive Perfecting Toner

Rebalance, replenish, and brighten your skin with Celavive Perfecting Toner.

Rebalance, Hydrate, and Brighten Your Skin with Celavive Perfecting Toner

Hydrate, create radiance, and promote healthy-looking skin with Celavive Perfecting Toner. A key step after cleansing, toner supports skin’s pH and prepares skin to take in moisturizer and skin treatments.

Perfecting Toner is a crucial part of your Celavive regimen. This unique formula enhances the action of your other products. You will also see a number of benefits in your skin’s appearance:

  • Reduced visibility of pores
  • Smoother-looking skin
  • Bright, even-looking skin tone
  • Refreshed, hydrated complexion

Celavive Perfecting Toner contains many potent ingredients, including BioPeptide-CS and Olivol24. It’s made without drying astringents, like alcohol or witch hazel. So, this soothing emulsion will help rebalance dry, oily, combination, or sensitive skin.

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Skin is Purified and Prepared to Absorb Products

Celavive Perfecting Toner is the perfect way to complete the cleansing process. Any traces of makeup or dirt are gently wiped away. Skin is conditioned. Impurities and blemish-causing compounds are also minimized, supporting clearer-looking skin.

Cleansing can remove natural oils from your skin. However, after cleansing, cells are more exposed to irritants and less able to absorb your skincare’s active ingredients. Celavive Perfecting Toner helps maintain the skin’s natural moisture levels and supports a healthy-looking pH.

When skin is properly cleansed and balanced, the cells are better able to absorb moisturizing and treatment products. Proper cleansing also helps to reduce the look of pores and leaves skin smooth.

Skin’s Moisture is Replenished with Celavive Perfecting Toner

In a private study, people using Celavive Perfecting Toner noticed a 180-percent increase in skin’s moisture level within the first 30 minutes of use. Skin’s moisture levels remained raised over the next three hours and beyond.

Celavive Perfecting Toner provides deep moisture to the skin. It is packed with some of the best skin hydrators:

  • Glycerin
  • Botanical Extract
  • Sodium PCA
  • Sodium Lactate
  • Tremella Mushrooms

These skin conditioners, and more, help support skin hydration by attracting and retaining moisture. When flakiness is reduced in dry skin, your complexion appears renewed.

Olivol24 is a blend of plant-based extracts that helps refresh skin and supports hydration, especially through heat and dry air. Olive-fruit extract, one of the ingredients in Olivol24, hydrates by acting like your skin’s natural oil. This similarity allows the blend to moisturize delicate, dry skin without causing irritation. Apple-, lentil-, and watermelon-fruit extracts support the natural skin barrier. This hydrating action aids the look of smooth, younger-looking skin.

Also found in Perfecting Toner, BioPeptide-CS helps support skin hydration for a refreshed, healthy-looking appearance. This unique blend of botanicals and bioactive peptides supports the skin’s natural barrier and promotes a well-nourished appearance.

Your epidermis—skin’s outermost layer—acts as a barrier. It is made of tightly packed skin cells that help retain moisture and shield the skin from environmental stressors. BioPeptide-CS helps fortify the skin barrier and nourish your skin’s natural lipids.

One of the key nutrients in BioPeptide-CS is southernwood extract (Artemisia abrotanum). This flowering plant is in the sunflower family. It is rich in carbohydrates containing a small number of simple sugars. By promoting hydration, these sugars help smooth and plump the skin to reduce the appearance of fine lines and wrinkles.

Applying glucosyl ceramide also benefits skin moisture. Ceramides are the major lipids found in the skin barrier.

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Skin Tone is Brightened

Reduce the appearance of uneven skin tone with the potent ingredients in Celavive Perfecting Toner. With continued use, you will see less blotchiness for refined, even-looking skin.

Protecting skin from environmental stressors helps promote a more even skin tone. Antioxidants in BioPeptides-CS help remove and destroy free radicals. And vitamin C—in the form of ascorbic acid—is a natural antioxidant that brightens and protects healthy-looking skin.

Many plant extracts also offer antioxidant protection and other benefits. A blend of seven botanical extracts in Perfecting Toner helps renew the complexion’s radiance and maintain a youthful appearance:

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Key Ingredients

  • BioPeptides-CS
  • Olivol24
  • Superfood Complex
  • Plum Extract
  • Xanthophylls Extract

See full list of ingredients
See glossary of Celavive Ingredients

Usage

Use twice daily (morning and night).

Start with clean skin. Close your eyes, hold the toner a few inches from your face, and mist onto skin (or apply to a cotton round and gently wipe your face and neck). Let it absorb naturally, without rinsing. It’s normal to feel a slight tingling sensation after application.

Caution: Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.

Ideal For

  • All skin types

Frequently Asked Questions About Celavive Perfecting Toner

  1. Tunón, H, Thorsell W, Mikiver A, and Malander A. Arthropod repellency, especially tick (Ixodes ricinus), exerted by extract from Artemisia abrotanum and essential oil from flowers of Dianthus caryophyllum. Fitoterapia 77.4 (2006): 257-61. Web. 30 May 2017.
  2. Natural mineral waters. BANA. N.p., 06 Nov. 2015. Web. 30 May 2017.
  3. Artemisia abrotanum. Wikipedia. Wikimedia Foundation, 21 May. 2017. Web. 30 May 2017.
  4. Bastos D, et al. Phenolic antioxidants identified by ESI-MS from yerba maté (Ilex paraguariensis) and green tea (Camelia sinensis) Extracts. Molecules 123 (2007): 423-32. Web. 31 May 2017.
  5. Dayan N, Kromidas L. Formulating, packaging, and marketing of natural cosmetic products. Hoboken: John Wiley & Sons, 2011. Print.
  6. Mimaki Y, Sashida Y, Kawashima K. Steroidal saponins from the bulbs of camassia cusickii. Phytochemistry 30.11 (1991): 3721-727. Web. 31 May 2017.
  7. Lima R, et al. Assessment of different biological capabilities of the Alpinia speciosa (Pers.) B. L. Burtt & R. M. Sm. Journal of Young Pharmacists. 7.4s (2015): 500-04. Web. 31 May 2017.
  8. Fereidoon S, Amarowicz R, He Y, Wettasignhe M. Antioxidant activity of phenolic extracts of evening primrose (Oneothera biennis): a preliminary study. Journal of Food Lipids 4.2 (1997): 75-86. Web. 31 May 2017.
  9. Amaral S, et al. Bioorganic and Medicinal Chemistry 17.5 (2009): 1876-883. Web. 31 May 2017.
  10. Vagi E, Simandi B, Suhajda A, Hethelyi E.  Food Research International 38.1 (2005): 51-57. Web. 1 June 2017.
  11. Bissett D, et al. Reduction in appearance of facial hyperpigmentation by topical N-acetyl glucosamine. Journal of Cosmetic Dermatology 6.1 (2007): 20-26. Web. 1 June 2017.
  12. Hashizume E, Nakano K, Morishita. Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus. Clinical, Cosmetic, and Investigative Dermatology (2013): 43. Web. 1 June 2017.
  13. Biological and Pharmaceutical Bulletin, Volume 35, Issue 12, 2012, pages 198–203; and Plant Foods for Human Nutrition, September 2011, pages 275–284.
  14. Cosmetics Info. Hydrolyzed Collagen [Internet] [cited 5 December 2017]. Available from http://www.cosmeticsinfo.org/ingredient/hydrolyzed-collagen-0
  15. Odjakova M, Opova E, Al Sharif M, Mironova R. 2012. Plant-Derived Agents with Anti-Glycation Activity, Glycosylation, Dr. Stefana Petrescu (Ed.), InTech, DOI: 10.5772/48186. Available from: https://www.intechopen.com/books/glycosylation/plant-derived-agents-with-anti-glycation-activity
  16. Shimoda H, et al. 2011. Effect of Cinnamoyl and Flavonol Glucosides Derived from Cherry Blossom Flowers on the Production of Advanced Glycation End Products (AGEs) and AGE-induced Fibroblast Apoptosis. Phytotherapy Research 25(9): 1328-1335.
  17. Mizutani Y, Mitsutake S, Tsuji K, Kihara A, Igarashi Y. 2009. Ceramide biosynthesis in keratinocyte and its role in skin functions. Biochimie 91(6): 784-90.
  18. Telang P. 2013. Vitamin C in Dermatology. Indian Dermatol Online J 4(2): 143-146. 
  19. Fiume Z. 2001. Final report on the safety assessment of malic acid and sodium malate. Int J Toxicol 20(Suppl 1): 47-55.

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Celavive Triple Action Eye Cream

Lessen the look of dark circles and puffiness with Celavive Triple Action Eye Cream.

Reveal Your Eyes’ Beauty and Brightness with Celavive Triple Action Eye Cream

You still have a youthful twinkle in your eyes. Frame them with bright, younger-looking skin that exudes vivacious vitality. Celavive Triple Action Eye cream targets three key concerns: visibly reducing discoloration, diminishing puffiness, and promoting healthy skin around the eyes, mouth, and chin.

This unique formula contains bioactive peptides, botanical extracts, and plant oils to revitalize youthful-looking eyes. Treat your most delicate skin to this lightweight, ultra-hydrating formula with powerhouse ingredients like Olivol24 and BioPeptide-CS.

Applied before your day or night moisturizer, Triple Action Eye Cream is an essential part of your Celavive skincare regimen. And you’ll start seeing these visible benefits with continued use:

  • Lessened appearance of dark circles and puffiness
  • A brighter look for your eyes
  • Delicate skin around the eye appears lifted and tighter
  • Smoother appearance for youthful-looking eyes

Celavive Triple Action Eye Cream is also clinically studied to improve:

  • Wrinkles by 9%
  • Fine lines by 16%
  • Firmness by 9%
  • Elasticity by 9%
  • Radiance by 16%
  • Dark circles by 11%

Visibly reduce the appearance of fine lines and wrinkles with this combination of bioactive peptides and botanical extracts. The formula targets key skin receptors to help your body bring out the look of your unique youthfulness.

Create a Bright Future for Your Eyes

Lessen the appearance of dark circles around your eyes. Using Celavive Triple Action Eye Cream helps you brighten your appearance and highlight that youthful sparkle in your eyes.

But how do dark circles develop in the first place? You might experience these circles for any number of reasons:

  • Family history
  • Irregular skin pigmentation
  • The pooling of blood in the area (especially after you sleep)
  • Shadows from puffiness
  • Time in the sun

As skin matures, changes in its appearance—such as increased visibility of blood vessels and uneven tone—can become more noticeable, especially around the delicate eye area. Celavive Triple Action Eye Cream features a powerful combination of ingredients that helps visibly brighten and revitalize the look of skin, targeting the appearance of dark circles and other signs of aging.

Enhance Your Eyes with Revitalizing Nutrients

Triple Action Eye Cream revitalizes and enhances the delicate skin around your eyes by supporting hydration and resilience to help your skin look and feel more vibrant.

At the heart of this cream is Olivol24, a botanical blend derived from watermelon, apple, lentil, and olive fruit that delivers 24 hours of continuous hydration while restoring a luminous glow. Complementing this ingredient is Superfood Complex, a potent mix of adaptogens from mushroom extract that supports the skin’s natural moisture barrier, ensuring long-lasting hydration and protection.

To further enrich your skin, the cream includes Abyssinian oil, packed with omega fatty acids and erucic acid to deeply nourish, soften, and improve the look of elasticity. Prickly pear oil (Opuntia ficus-indica seed oil) adds a boost of vitamin E and essential fatty acids, offering intense hydration to help moisturize and refresh the look of dull, tired skin.

Additionally, Ki’Leaft, an extract from Actinidia chinensis leaves, features polyphenols and sugars that support the natural skin barrier to promote a firmer, more hydrated appearance. Finally, Xanthophylis Extract, rich in lutein and zeaxanthin, helps support the skin’s resilience against environmental stressors like blue light, helping to reduce signs of fatigue and maintain a youthful, radiant appearance.

Multi-Peptide Formula Helps Smooth Your Skin’s Appearance

Smooth and brighten the delicate skin around your eyes with the advanced Multi-Peptide Formula in Celavive Triple Action Eye Cream. This powerful blend of bioactive peptides—including BioPeptide-CS, Haloxyl, and Matrixyl Morphomics—works to even skin tone, reduce the appearance of dark spots, and promote a more radiant, youthful complexion.

Peptides are short chains of amino acids that act as messengers in the skin, stimulating collagen production—the key protein responsible for maintaining firmness and elasticity. As collagen naturally declines with age, these peptides help replenish and support its production, minimizing the appearance of fine lines and wrinkles.

BioPeptide-CS, powered by USANA InCelligence Technology, features a unique combination of Palmitoyl Tripeptide-38, Hexapeptide-48 HCI, southernwood extract, and coffee-seed extract. This blend works to improve the appearance of key elements associated with healthy-looking skin.

The peptides in BioPeptide-CS help with hydration by supporting the skin’s natural moisture-retention processes for a more moisturized complexion. Additionally, these messengers target receptors in your skin that help promote healthy levels of hyaluronic acid for a visible plumping effect. If you’ve never heard of hyaluronic acid, it’s an important component of your skin. It has the ability to retain water, which makes it essential for skin hydration.

Other peptide-based ingredients include Haloxyl, which helps improve the appearance of dark circles and puffiness by supporting microcirculation and visibly reducing pigmentation-related discoloration, and Matrixyl Morphomics to help reduce the appearance of vertical wrinkles.

Plant Extracts that Revitalize and Protect

To further enhance the skin-smoothing and rejuvenating effects of Celavive Triple Action Eye Cream, a carefully selected blend of botanical extracts helps promote the appearance of smoother, more radiant skin by supporting surface-level hydration. These plant-based ingredients are rich in essential nutrients and antioxidants that help support the skin’s natural vitality and resilience, especially in the delicate under-eye area.

Among these is Encapsulated Liposomal Bakuchiol, a plant-derived ingredient known for its gentle benefits, sourced from the Babchi plant. This ingredient promotes the appearance of smoother, more refreshed skin by supporting visible skin revitalization while its liposomal encapsulation ensures deeper absorption and a gradual release—making it ideal for sensitive skin.

Complementing this are other powerful botanicals, including Olivol24 for long-lasting hydration and glow, the Superfood Complex to support the skin’s natural moisture barrier, and nutrient-rich oils like Abyssinian and Prickly Pear to condition the skin and promote a smoother, more supple-looking complexion. Energizing extracts like Ki’Leaft and antioxidant-rich Xanthophylis help refresh the look of skin and promote a more radiant, healthy-looking complexion.

Clinical Study

An eight-week study was conducted to evaluate the efficacy of Celavive Triple Action Eye Cream on the appearance of the skin around the eyes. The study included 36 women between the ages of 35 and 75, representing diverse racial backgrounds and a range of skin types, including combination, dry, and normal. Participants presented with mild to moderate under-eye puffiness, dark circles, fine lines, wrinkles, and a lack of firmness or radiance.

Subjects were instructed to apply the cream twice daily as directed to the skin around the eyes, between the brows, the marionette lines, cheeks, upper lip, and lower face. The first application was performed in the clinic immediately following baseline assessments. Product use continued for eight weeks, with measurements taken at baseline, week 2, week 4, and week 8 to assess improvements in skin appearance.

Results show that under the conditions of the test, Triple Action Eye Cream was effective in improving the cosmetic appearance of skin conditions over the course of 8 weeks, particularly improving the appearance of dark circles under the eyes by nearly 10% and reducing the visibility of fine lines by over 16%.

This graph shows the results at week 8 of the study. Subjects saw an improvement in the eye area, upper lip, marionette area, lower face, and overall radiance.

% Improvement From Baseline to Week 8

Key Ingredients

  • BioPeptide-CS
  • Olivol24
  • Superfood Complex
  • Haloxyl
  • Matrixyl Morphomics
  • Abyssinian Oil
  • Ki’Leaft
  • Encapsulated Liposomal Bakuchiol
  • Opuntia ficus-indica Seed Oil
  • Xanthophylis Extract

See full list of ingredients
See glossary of Celavive Ingredients

Usage

Directions: Massage product around the eye area and gently pat the product into your skin.

Caution:  Store in a cool, dry place. Avoid contact with eyes. Discontinue use if irritation occurs.

Ideal For

  • All skin types

Frequently Asked Questions About Celavive Hydrating Eye Essence

Submit your question at the link at bottom of page.

  1. Ershadi M, Itzanaki E. Skin-care formulation for treating anti-aging and wrinkle reduction. Maryam Ershadi, Emanuel Itzanaki, assignees.  Patent 20160354299. 8 Dec 2016.
  2. Kim S, et al. Effects of flavonoids of gingko biloba on proliferation of human skin… Skin Pharmacology and Physiology 10.4 (1997): 200-05.
  3. Yuan W, et al. The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects. American Journal of Clinical Dermatology 14.2 (2013): 147-53.
  4. Lither K. Peptides, amino acids, and proteins in skincare? Cosmetic and Toiletries Magazine. Oct 2007: 26-34. Print.
  5. Co. Ltd, HORUS. “Raw Materials for Cosmetics…” Horus Co., Ltd. Horus Co., Ltd., n.d.
  6. Mayo Clinic Staff. 13 Oct. 2106. Dark Circles Under Eyes. Retrieved from https://www.mayoclinic.org.
  7. Venereol A. Dermatol. Skin hydration and hyaluronic acid. PubMed.gov. 2010 April; 137 Suppl 1:S23-5. doi: 10.1016/S0151-9638(10)70005-3.
  8. Mahadevan S, Park Y. Multifaceted Therapeutic Benefits of Ginkgo biloba L.: Chemistry, Efficacy, Safety, and Uses. Journal of Food Science Volume 73, Issue 1, January/February 2008: Pages R14-R19.
  9. Smith JV, Luo Y. Appl Microbiol Biotechnol (2004) 64: 465.

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Celavive Protective Day Cream and Lotion

Hydrate and protect your delicate facial skin with nourishing moisturizers and a broad-spectrum SPF 30 sunscreen.

Hydrate and Protect with Celavive Protective Day Cream and Lotion

You want to put your best face forward every day. But, dry or dehydrated skin can look dull and lifeless. Fortunately, the right moisturizer can help reveal your complexion’s natural vitality. Celavive® Protective Day Cream or Protective Day Lotion will replenish hydration and protect your delicate facial skin from signs of premature aging caused by the sun.

Both products are designed with the right balance of active ingredients for your skin’s unique needs:

Dry, sensitive: Celavive® Protective Day Cream—a rich moisturizer that deeply replenishes parched skin.

Oily, combination: Celavive® Protective Day Lotion—a lightweight liquid that moisturizes without adding excess oil or grease.

Daily sun protection is essential to keeping your skin looking healthy. Celavive daytime moisturizers help protect skin from the visible aging effects of the sun’s rays with a broad-spectrum SPF 30 sunscreen. Nourishing moisturizers, potent botanicals, plus the exclusive Olivol® Botanical Blend also help deliver benefits to your complexion:

  • Appearance of healthy, hydrated skin
  • Reduced visible fine lines and wrinkles
  • Look of a smooth, even skin tone

Use every morning to complete your regimen of Celavive products and prime skin for daily sun exposure.

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[celavivedaylotion]

Protect and Moisturize Daily for Healthy Radiance

Your face goes through a lot every day. It’s exposed to weather and climate extremes, pollutants, or other lifestyle factors that can cause it to become dry or dehydrated. Age, too, can impact skin’s moisture levels. Declining moisture can cause your skin to look even older than you really are. And one of the biggest contributors to skin dryness and the appearance of premature aging is time spent in the sun.

So, what can you do to alleviate dry or dehydrated skin and fight the signs of aging?

While they act similarly, dehydrated skin and dry skin are different. Dry skin lacks oil and tends to flake (it often is dehydrated, too). Dehydrated skin lacks water and can feel tight, but can also be oily. Yes, oily skin can become dehydrated! In fact, dehydrated skin can cause overproduction of oil as cells work to restore a proper balance.

Most people’s skin needs more water, but not all skin needs more oil. This is why it’s important to choose a moisturizer created for your skin type.

Applying the right facial moisturizer daily can help keep skin looking youthful and vibrant. These formulas replenish dry or dehydrated skin with ingredients that attract and lock in moisture. Proper hydration helps ensure your skin’s moisture barrier function normally, so your skin doesn’t show signs of wrinkles prematurely. You can also support skin hydration from the inside by drinking plenty of water and eating omega-3 or linoleic fatty acids in your diet.

Diligently using sunscreen and smart sun protection are also crucial for supporting long-term skin health. Damage from sun exposure poses a series of serious problems for the skin. Sunburn can cause wrinkles, dark spots, and can increase the risk of skin cancer. Dermatologists recommend that you protect your skin from the sun’s damaging rays in three key ways:

  1. Limiting sun exposure, especially between 10 a.m. and 2 p.m.
  2. Wearing protective hats and clothing
  3. Applying a broad-spectrum sunscreen with an SPF of 30 or higher every day, even if it’s cloudy or you aren’t planning on spending time outdoors

Celavive® Protective Day Cream and Lotion Replenish Moisture for a Healthy, Firmer Appearance

Rehydrate and soften the look of your skin for an instant boost of luminosity and reduced appearance of fine lines and wrinkles with your Celavive daytime moisturizer. Each formula is made with the emollients best suited for your skin type. Both also deliver powerful active ingredients to replenish moisture, including shea butter (Butyrospermum parkii), nourishing plant extracts, and the exclusive Celavive Olivol Botanical Blend.

Shea butter is a rich moisturizer. Extracted from nuts of the African shea tree, shea butter has been used for years as an emollient in moisturizers and lotions. It contains large amounts of long-chain fatty acids, which absorb quickly to help restore moisture and support healthy collagen—a key structural protein that keeps your skin looking firm.

Supporting lipids in the top layer of your skin also helps skin look firmer. A unique soybean (Glycine soja) extract in the Celavive moisturizers acts like a natural lipid found in your skin’s moisture barrier known as ceramide-3. The outermost layer of the skin is comprised of high levels of ceramides—as much as 50 percent of total lipid composition. By helping your skin retain water in the lipid barrier, this extract delivers nourishing hydration.

The Olivol Botanical Blend sets Celavive apart from other moisturizers. It gives your skin a full 24-hour boost of skin-plumping hydration. Your skin’s natural moisture is enhanced with science-backed botanicals: Olivol olive (Olea europaea) fruit extract, plus watermelon-rind (Citrullus lanatus), apple (Pyrus malus), and lentil (Lens esculenta) fruit extracts. This soothing blend helps skin capture and keep water to reinforce your skin-barrier’s protective moisture.

To help fight flakiness and deliver even more hydration to dry, sensitive skin, Protective Day Cream contains oil- and fatty-acid based moisturizers. This includes caprylic/capric triglyceride, which is derived from coconut oil and glycerin. Salicornia herbacea comes from a plant that grows in the salt marshes along the coastline of South Korea. It delivers an added boost of moisture to enhance natural hyaluronic acid.

Defend Against Visible Signs of Aging with Broad-Spectrum SPF 30 (PA++) Sunscreen

There is perhaps nothing more important for maintaining skin’s health and youthful appearance than protecting it from the sun’s damaging rays. This is why the American Academy of Dermatology recommends you apply a broad-spectrum sunscreen with an SPF 30 or higher every day before you go outside.

There are two types of ultraviolet (UV) rays from the sun that can harm your skin: UVA and UVB. UVA rays can age the skin, causing wrinkles and age spots. UVB rays can burn your skin. Both are potentially harmful. So, you want a broad-spectrum sunscreen to protect your skin from both.

A broad-spectrum sunscreen with SPF 30 should block most rays effectively on most days. Sun protection factor (SPF) is based on how long it takes to sunburn skin that’s been treated with sunscreen compared to no sunscreen. It does not measure the effects of UVA.

Celavive daytime moisturizers use four UV filters for effective and safe broad-spectrum sun protection. UV filters have been shown to work more effectively when formulated together. This is because they can filter a broader spectrum of light when used together and provide more complete coverage on the skin.

The four UV filters in the Celavive Daytime Protective Lotion and Cream that help prevent sunburn are as follows:

  • Avobenzone—protects primarily against UVA rays but offers some protection against UVB as well
  • Octocrylene—a moisturizing sunscreen that absorbs UVB light and also helps stabilize Avobenzone, which can degrade in light over time
  • Homosalate—absorbs UVB rays
  • Octinoxate—an effective UVB absorber

Your Celavive daytime moisturizer provides even more protection against the effects of the sun’s rays with rejuvenating sweet basil (Ocimum basilicum L.) hairy root culture extract. Basil extract helps keep the skin looking healthy with coverage and protection from the sun. In addition to antioxidant activity, this extract also offers benefits for conditioning and soothing the skin after sun exposure to keep visual imperfections and blemishes at bay.

Please note that on the days you spend outdoors, a higher SPF doesn’t mean you can spend more time in the sun without reapplying. No matter what SPF you use, reapply every two hours. For even more defense against visible aging, apply the topical antioxidants in Celavive Vitalizing Serum under your sunscreen.

Reveal Beautifully Smooth, Luminous Skin

When your skin is hydrated, it looks dewy and luminous. To further revitalize your skin, Celavive Daytime Protective Cream and Lotion include unique botanical extracts to give the skin a tightened, toned appearance.

A complex of Korean (Panax ginseng), American (Panax quinquefolium), and Siberian (Acanthopanax senticosus) ginseng extracts provides antioxidant and firming action for a youthful look. Asian women have used ginseng as part of their beauty routine for hundreds of years. The extracts contain many revitalizing bioactive compounds, including ginsenosides, polysaccharides, phytosterols, peptides, fatty acids, and more. The compounds in ginseng can promote the appearance of a bright, even skin tone.

To refine the look of pores, Eijitsu rose (Rosa multiflora) extract helps condition and tighten the skin. A source of flavonoids, this flower is native to Asia. It helps balance oil to help minimize the appearance of pores for a radiant skin tone and smooth texture.

[celavivedaycream]

[celavivedaylotion]

Key Ingredients

See full list of ingredients:
Protective Day Lotion
Protective Day Cream

See glossary of Celavive Ingredients

Usage

Protective Day Lotion
Shake well and apply a pearl-sized amount to face and neck.

Protective Day Cream
Apply 2-3 pumps of product to face and neck.

Apply generously and evenly 15 minutes before sun exposure. Reapply at least every 2 hours. Use a water-resistant sunscreen if swimming or sweating.

Ideal For

  • Protective Day Cream is recommended for those with dry, sensitive skin.
  • Protective Day Lotion is recommended for those with oily, combination skin.

Warnings

For external use only. Do not use on damaged or broken skin. When using this product keep out of eyes. Rinse with water to remove. Stop use and ask a doctor if rash occurs.

Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

Sun Protection Measures

Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including:

  • limit time in the sun, especially from 10 a.m.–2:00 p.m.
  • wear long-sleeved shirts, pants, hats, and sunglasses
  • Children under 6 months of age: Ask a doctor

Frequently Asked Questions About Celavive Protective Day Cream and Day Lotion

Many markets share the same formulas for our Celavive Protective Day Cream and Protective Day Lotion.* However, regulations for cosmetic products vary in every country, which impacts the claims allowable on product packaging.

Currently (as of March 2026), there is no SPF (sun protection factor) rating on Celavive day moisturizers in Canada. And Australia/New Zealand receives a product labeled as SPF 15.

In the case of Canada, sunscreens are regulated as pharmaceutical drugs. In Australia/New Zealand, moisturizers containing sunscreen with an SPF greater than 15 are regulated as therapeutic goods. As such, the requirements and regulations to make the same SPF 30 claim would have increased the product cost. Therefore, the SPF claim was removed or altered as determined necessary for best availability.

*In general, formulas for Celavive Daytime Protective Cream and Lotion are shared as follows:

  • United States, Canada, Australia/New Zealand, Mexico, share a formula. With the US and Mexico being able to claim SPF 30.
  • Hong Kong, Singapore, Malaysia, Philippines, Japan, Taiwan, and Korea share a formula. All markets within this region can claim SPF 30.

Kraft JN, Lynde CW. “Moisturizers: What They Are and a Practical Approach to Product Selection.” Skin Therapy Letter 10.5 (2005): 1-12. Web. 27 June 2017.

Goreja, W. G. Shea Butter: the Nourishing Properties of Africa’s Best-kept Natural Beauty Secret. New York: Amazing Herbs Press, 2004. PDF.

Israel MO. 2014. Effects of topical and dietary use of shea butter… Am Jour Lif Sci 2(5): 303-307.

Adiguzel A, et al. “Antimicrobial Effects of Ocimum basilicum (Labiatae) Extract.” Turk J Biol 29 (2005): 155-60. Web. 27 June 2017.

Rasul A, Akhtar N. 2011. Formulation and in vivo evaluation for anti-aging effects of an emulsion containing basil extract using non- invasive biophysical techniques. Daru 19(5): 344-50.

Velasco MV, et al. 2008. Broad spectrum bioactive sunscreens. Int J Pharm 363(1-2): 50-7.  

Kale S, et al. 2010. Formulation and in-vitro determination of sun protection factor or Ociumum basilicum, Linn. Leaf oils sunscreen cream. Int Jour Pharm and Pharmaceut Sci 2(4): 147-149.

Nikolić, S., C.m. Keck, C. Anselmi, and R.h. Müller. Skin photoprotection improvement: Synergistic interaction between lipid nanoparticles and organic UV filters. International Journal of Pharmaceutics414.1-2 (2011): 276-84. Web. 27 June 2017.

Gaspar, L., and P. Campos. “Photostability and efficacy studies of topical formulations containing UV-filters combination and vitamins A, C and E.” International Journal of Pharmaceutics 343.1-2 (2007): 181-89. Web. 27 June 2017.

Kim EJ, et al. IFCC. Skin moisturizing efficacy of salicornia herbacea L. extract by enhanced skin barrier [Internet] [accessed 11 January 2018] Available at http://tst.pg2.at/abstracts/a0087.html?zoom_highlight=

Kasprowicz S. Dermatology Times. Ginseng may provide benefits on multiple fronts [Internet] [accessed 11 January 2018] Available at http://dermatologytimes.modernmedicine.com/dermatology-times/news/ginseng-may-provide-benefits-multiple-fronts?page=0,0

Kim K. 2015. Effect of ginseng and ginsenosides on melanogenesis and their mechanism of action. J Ginseng Res 39(1): 1-6.

Choi H, et al. 2016. Phlorizin, an Active Ingredient of Eleutherococcus senticosus, Increases Proliferative Potential of Keratinocytes with Inhibition of MiR135b and Increased Expression of Type IV Collagen. Oxid Med Cell Longev 2016: 3859721.

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A clinical study was conducted by USANA Health Sciences to evaluate the efficacy and tolerance of Celavive Resurfacing Serum. Celavive Resurfacing Serum is a topical skincare product that contains a blend of alpha and beta hydroxy acids, niacinamide, peptides, and bakuchiol.

Study Design

The study included 33 women with mild to moderate skin concerns. They used USANA Resurfacing serum for 12 weeks. The women came from different races and ethnicities, and they were between 39 and 65 years old, with an average age of 56.

Clinical skin measurements were taken before the participants began using Resurfacing Serum, and again after using the product for 2, 4, 8, and 12 weeks. The participants also completed a self-assessment questionnaire to evaluate how they felt about their skin after using the product.

Results

Resurfacing Serum was well-tolerated by all the subjects. Users showed statistically significant improvements in the appearance of their skin in just two weeks. These measurements further improved as they continued to use the product through weeks 4, 8, and 12.

Over 80% reported that it was the best their skin had felt in a long time. Some of the specific improvements they saw were that Resurfacing Serum helped their skin appear clearer, firmer, and more radiant. It helped reduce the appearance of pores, fine lines, and wrinkles. They also reported that the product was easy to use, and 97% of them said that they would recommend the product to others.

Visual Results

Key Findings

  • Results were visible in as little as four weeks
  • Over the 12-week study clinical measurements showed a:
    • 23% reduction in acute hyperpigmentation
    • 15.8% reduction in the appearance of fine lines
    • 11.6% reduction in the appearance of pores
    • 8.9% improvement in skin clarity
    • 8.6% improvement in skin radiance
  • 81.8% of participants reported it was the best their skin had felt in a long time
  • 97% of participants would recommend the product

Improvements in Clinical Skin Measurements: Participants Showing Improvement

Improvements in Clinical Skin Measurements: Measured Change

Participant Self-Assessment at Week 12

 

Daily life takes strength. From lifting your latest haul of groceries to carrying your growing toddler up the stairs to conquering your fitness goals. Keeping your muscles strong requires regular exercise and consuming enough protein. This essential macronutrient provides the amino acids that are vital for building and maintaining healthy lean muscle mass.

USANA Whey Protein Isolate is formulated for athletes, aging individuals, and anyone who needs more protein in their diet to reach their daily recommended intake. With only four ingredients total, this formula simplifies a classic supplement product.

Benefits of USANA Whey Protein Isolate:

  • Supports muscle growth
  • Recovery support
  • Weight management
  • Supports muscle retention
  • Easily digestible
  • Great as a post workout
  • Full amino acid profile supports overall nutrition

Each serving is packed with 25 grams of 100% pure, grass-fed whey protein, without the fillers and sugar you might find in other protein powders on the shelves. Isolate protein is its most bioavailable form, so your body can easily absorb and utilize the maximum amount of protein in each scoop. With a nearly flavorless profile, Whey Protein Isolate mixes well with any liquid or food you choose to combine it with, while tasting great on its own.

Whether you’re a frequent gym goer looking to build lean muscle mass, a casually active person looking to support overall nutrition, or someone concerned about healthy aging, everyone can benefit from added protein in their daily diet.

Whey is a byproduct of milk and cheese production. It comes from the watery part of milk that separates from curds, the solid clumps that form during cheese production. It is a completely safe and natural food that contains all nine essential amino acids, vitamins, and minerals.

Boost Your Protein Intake to Fuel Your Muscles

Across the world, people are not consuming enough protein from quality sources. This is especially concerning for elderly people, active individuals, and athletes. Everyone needs adequate amounts of protein for optimal health.

Protein deficiency can impair your immune system, stunt your growth, weaken your bones and muscles, and much more. It also becomes especially important to focus on maintaining muscle as you get older. Muscle mass and function are gradually lost over the years. By age 60, you may begin to lose the muscle strength and function needed to stay independent and energetic into your senior years (especially if you tend to have a more sedentary lifestyle). And this decline can be even more pronounced in post-menopausal women.

The good news is that some muscle loss can be avoided. Mature individuals can help maintain a good quality of life through working to stay strong by exercising regularly and by supporting muscle maintenance by consuming enough protein.

Because protein helps you feel fuller, longer, it may help you eat less if you’re trying to cut calories. And protein’s benefits for weight management don’t stop there. Muscles tend to burn more calories than fat, even when you’re at rest. So, by helping to maintain your lean body mass, a diet with increased protein can help support efficient energy metabolism.

By incorporating USANA Whey Protein Isolate into your diet, you’ll support a variety of long-term health benefits: muscle growth and retention, healthy aging, weight management, and overall nutrition.

Understanding Protein’s Role in the Body

Protein is an important part of a healthy diet. Proteins are made up of chemical building blocks called amino acids. On a biochemical level, your body uses amino acids to synthesize proteins that support a wide variety of structures and functions throughout the body.

Protein plays a role in:

  1. Growth and Repair: Protein repairs and builds muscle. But it’s also involved in repairing other tissues, like skin, hair, nails, and bone.
  2. Energy: Protein supports energy production, but it can also be used as an energy source itself.
  3. Immunity: The antibodies your body needs to fight infections and illness are made of amino acids that come from your dietary protein.
  4. Oxygenation: Protein is needed for your blood to carry oxygen throughout the body.
  5. Metabolism: Your protein intake supports a healthy metabolism, which burns more calories throughout the day.
  6. Hormones and Enzymes: Practically all hormones and enzymes in the body are proteins made from the amino acids in the protein you consume.

The body doesn’t store protein the way it stores carbohydrates or fats. That’s why protein intake from your diet is so important.

How Much Protein Do I Need?

To maintain health, the Institute of Medicine recommends most people consume eight grams of protein for every 20 lbs. of body weight per day (.8 g/kg).

If you’re trying to manage your weight, higher intakes also may be needed. Research has shown that it’s important to consume more protein than your usual intake to see improvements. You may need about 37 percent more protein than the general recommendation, or 11 grams for every 20 lbs. of body weight (1.2 g/kg).

Athletes, too, need more protein. If you’re very active, aim to consume up to 18 grams of protein for every 20 lbs. of body weight per day, depending on the intensity of training.

Let’s look at a couple examples.

Mary is 35 years old and weighs 150 lbs. She exercises daily, but otherwise works at a sedentary desk job. That means she would need around 60 grams of protein per day to maintain her health. She should aim for about 82 grams of protein per day if she is focused on managing her weight.

Joe is a 150-pound professional athlete. So, he exercises strenuously and for extended lengths of time daily. That means he could need up to 135 grams of protein per day.

But that’s not all you need to consider for the best results.

The key to maximizing the benefits of your protein consumption is spreading it into roughly equal amounts at every meal. This is a more effective approach for building muscle than skewing protein intake toward only one or two meals. So, once you’ve calculated how much protein you need, divide that equally across the number of meals/snacks you generally eat every day.

If you’re interested in learning more about the scientific research behind protein recommendations, the International Society of Sports Nutrition (ISSN) is a great place to start. Bringing together top experts from various fields: nutritionists, biologists, medical practitioners, clinical researchers, and more, the ISSN’s work on protein intake is highly regarded across the world.

USANA Whey Protein makes it easy to add protein to your diet when you need it. For example, many people don’t get enough protein at breakfast. Adding USANA Whey Protein to your first meal is a great way to have a complete, balanced breakfast, and a strong start to your day.

Usage Instructions

USANA Whey Protein is a versatile supplement that can be used in various ways to boost your protein intake. You can take your protein within 30 minutes after exercise for a post-workout recovery boost. But it’s also great in the morning, between meals, or before bed.  Here are some usage tips:

  • General Tips for Best Results
    • Measure Accurately
      • Use the scoop provided to measure the protein powder accurately
    • Blend Well
      • Ensure you mix the powder thoroughly to avoid clumps. A blender or shaker bottle works best.
    • Adjust Liquid
      • If desired, you can use milk or a milk alternative to add more calories to your protein shake. Whether you use water or milk, you can always adjust the amount of liquid you use to reach your preferred consistency.
  • Protein Shake
    • Mix one scoop of USANA Whey Protein with 4-6 ounces of water, or milk in a shaker bottle or blender. Shake well and consume.
    • Or add a scoop of USANA Whey Protein to your favorite smoothie recipe. Combine fruits, vegetables, yogurt, and liquids in a blender.
  • Other Recipes
    • Protein Pancakes: Mix one scoop into your pancake batter for a protein boost.
    • Baked Goods: Add one scoop of USANA Whey Protein to muffins, cookies, and brownies.
  • Storage
    • Keep your USANA Whey Protein in a cool, dry place away from direct sunlight

Key Ingredients

See full list of ingredients

Ideal For

  • Any adults struggling to get enough protein in their diet.
  • Elderly
  • Active individuals

Frequently Asked Questions

Within 30 minutes post-workout is a great time to take your protein. Research has also demonstrated benefits to the body when protein is consumed in the morning or before bed. It’s also important to consume your daily recommended protein intake throughout your day and meals, rather than all at once.

Yes, USANA Whey Protein is a completely vegetarian product. However, it is not suitable for vegans because it is derived from cow’s milk.

USANA Whey Protein contains only 4 ingredients total. It is lightly flavored but contains no added sugar, color or fillers.

Yes, this is a gluten-free product.

Cooke, M. B., Rybalka, E., Stathis, C. G., Cribb, P. J., & Hayes, A. (2010). Whey protein isolate attenuates strength decline after eccentrically-induced muscle damage in healthy individuals. Journal of the International Society of Sports Nutrition, 7(1), 30.

Buckley, J. D., Thomson, R. L., Coates, A. M., Howe, P. R., DeNichilo, M. O., & Rowney, M. K. (2010). Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise. Journal of science and medicine in sport, 13(1), 178-181.

Joy, J. M., Lowery, R. P., Wilson, J. M., Purpura, M., De Souza, E. O., Wilson, S. M., … & Jäger, R. (2013). The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutrition journal, 12, 1-7.

Burd, N. A., West, D. W., Moore, D. R., Atherton, P. J., Staples, A. W., Prior, T., … & Phillips, S. M. (2011). Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men. The Journal of nutrition, 141(4), 568-573

Burd, N. A., Yang, Y., Moore, D. R., Tang, J. E., Tarnopolsky, M. A., & Phillips, S. M. (2012). Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. British Journal of nutrition, 108(6), 958-962.

West, D. W., Abou Sawan, S., Mazzulla, M., Williamson, E., & Moore, D. R. (2017). Whey protein supplementation enhances whole body protein metabolism and performance recovery after resistance exercise: a double-blind crossover study. Nutrients, 9(7), 735.

Do you ever feel restless when it’s time for sleep? Like your mind or body just isn’t tired yet? If so, you are not alone. Sometimes your nervous system needs some help getting the message. That it’s late, you have a busy day tomorrow, and it’s time for bed.

USANA Rest Complete is a comprehensive sleep supplement that helps your body and mind prepare for bedtime. Take Rest Complete one hour before bedtime to relax your muscles, reduce anxiety, and promote restful sleep.*

Rest Complete contains:

  • Melatonin to help promote drowsiness and restful sleep*
  • Ashwagandha to calm your mind and reduce anxiety*
  • GABA (Gamma-Aminobutyric Acid) and L-theanine to calm your nerves and relax your muscles*

Sleep is essential for recharging your body and mind. It helps ensure that you feel fresh and alert as you live your life. Sleep supports brain functions like concentration, clear thinking, and memory processing. It also helps regulate emotions, supports your ability to manage stress, consolidates memories for learning, and improves decision making and problem-solving abilities.

Sleep is important for your physical health too. Good sleep helps aid in the healing and repair of all muscles, tissues, and your individual cells. Additionally, sleep supports the immune system to fight off infections. Sleep also affects hormones that control appetite, which can influence body weight. In essence, sleep is as vital to our survival as food and water. It impacts nearly every type of tissue and system in your body.

Unfortunately, when sleep doesn’t come easily, its benefits remain just out of reach. There are many different reasons that you might have trouble getting to sleep or staying asleep through the night.

Outside factors like staying up late watching tv or looking at your phone can disrupt your sleep for hours after the lights go out. Internal thoughts and worries about family, work, finances, or even worrying about sleep itself can also make it hard to quiet your mind and find rest.

Melatonin Helps Support Your Natural Sleep Cycle

Melatonin is a hormone that plays a crucial role in initiating sleep. It is synthesized in the brain’s pineal gland. Its primary function is to regulate the body’s sleep-wake cycles. In essence, it helps keep your body in sync with the 24-hour cycle of the sun.

Melatonin production is halted during daylight hours. Then, as daylight fades and evening approaches, melatonin production increases. Throughout the night, elevated melatonin levels cue your body that it’s time to rest.

Modern life frequently exposes us to artificial lighting at night. It comes from the TV, phone screens, or the lights throughout your home. This light inhibits melatonin production and can disrupt your natural circadian rhythm—the body’s internal clock. When that happens, it can be difficult to wind down for sleep and get a good night’s rest.

Consider Rest Complete to ensure consistent melatonin levels throughout the night. Rest Complete is designed to align your body with the Earth’s natural cycle of light and darkness, fostering a more organic sleep rhythm. Taking Rest Complete roughly an hour before sleep can lead to reduced alertness, increased drowsiness, and ultimately sleep.*

Melatonin supplementation has other uses too. For those concerned that sleep deprivation might disrupt a holiday or cause tiredness during a business trip, melatonin is an ideal travel partner. It’s known to alleviate jet lag, particularly when traveling across multiple time zones. Melatonin can help realign your body and mind with the 24-hour light and dark cycle found in your travel destination.

Beyond aiding sleep, melatonin also contributes to cellular health. It functions as an antioxidant, scavenging free radicals, and bolstering the body’s endogenous antioxidant enzymes. By combating oxidative stress that damages cells, melatonin not only supports sleep but also enhances the body’s restorative activities during slumber.

Rest Complete Helps You Feel Calm and Eases Your Mind

Lights might not be the only thing keeping you up at night. When life becomes busy and hectic, it can be difficult to turn your mind off when it comes time to go to sleep. Rest Complete takes a holistic approach to helping you sleep, and helps you address a variety of different aspects that might be keeping you up at night.*

Rest Complete contains Ashwagandha, which is known to have a myriad of health benefits. This potent herb is included in Rest Complete because it helps regulate cortisol and neurotransmitter levels, contributing to a balanced stress response.*

Ashwagandha works by modulating the body’s stress mechanisms in a way that mimics the effects of mild stress without causing any adverse effects. This process effectively boosts your body’s adaptability, enabling you to stay calm amidst various kinds of stress—physical, mental, or environmental.

Ashwagandha has other benefits such as antioxidant properties, and physiological and psychological benefits. It is known to promote a sense of tranquility and aids in sustaining cognitive functions. This combination of benefits helps put your mind at ease, which is conducive to restful sleep.

Rest Complete Helps Calm Your Nerves and Muscles

Rest Complete contains GABA (Gamma-Aminobutyric Acid)—a neurotransmitter that helps to calm the body and mind by turning off wakefulness and quieting nerve activity. It also contains L-theanine, an amino acid that signals to your body that it needs to make more GABA too. This helps maintain elevated GABA levels in your body throughout the night.*

GABA is an amino acid neurotransmitter. It helps facilitate communication between neurons. Notably, GABA functions as an inhibitory neurotransmitter, halting some message transmissions and slowing the rate of other neural communications.

The collection of neurons that utilize GABA, known as the GABAergic system, act as a regulatory mechanism akin to a brake pedal. It helps slow down the transmission of information, lessen the actions of other neurotransmitters, and lower the excitation of brain neurons.

The experience of stress, anxiety, or fear is often linked to excessive neuronal activity and stimulation. GABA’s reputation for fostering relaxation and a sense of calm is tied to its ability to counteract such overactivity.

In the realm of sleep regulation, GABA plays a pivotal role. When it’s time to rest, the GABAergic system intensifies its function, soothing the nervous system and inducing tranquility. This process aids in the shift from wakefulness to the initial sleep stage and beyond. Hormones such as melatonin target GABA receptors to further enhance the calming action of the GABAergic system.

Key Ingredients

  • Melatonin
  • Ashwagandha
  • GABA
  • L-theanine

See full list of ingredients

Usage

Adults take one (1) tablet as needed one hour before bedtime for relief of occasional sleeplessness.

Ideal For

  • Adults struggling with occasional sleeplessness
  • Night shift workers
  • Jet Lag

https://www.nigms.nih.gov/education/pages/Factsheet_CircadianRhythms.aspx

Han KS, Kim L, Shim I. 2012. Stress and sleep disorder. Exp Neurobiol 21(4): 141-150.

Czeisler CA. 2013. Perspective: casting light on sleep deficiency. Nature 497(7450): S13.

Peuhkuri K, Sihvola N, Korpela R. 2012. Dietary factors and fluctuating levels of melatonin. Food Nutr Res 56: 10.3402/fnr.v56i0.17252.

Ramis MR, et al. 2015. Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review. Curr Med Chem 22(22): 2690-711.

Reiter RJ, Tan DX, Osuna C, Gitto E. 2000. Actions of melatonin in the reduction of oxidative stress. A review. J Biomed Sci 7(6): 444-58.

Vielma JR, et al. 2014. Effects of melatonin on oxidative stress, and resistance to bacterial, parasitic, and viral infections: a review. Acta Trop 137: 31-8.

Hosseinzadeh A, et al. 2016. Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin. J Pineal Res 61(4): 411-425.

Posadzki PP, et al. 2018. Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action. BMC Med 16(1): 18.

Xie Z, et al. 2017. A review of sleep disorders and melatonin. Neurol Res 39(6): 559-565.

Amstrup AK, Sikjaer T, Mosekilde L, Rejnmark L. 2015. The effect of melatonin treatment on postural stability, muscle strength, and quality of life and sleep in postmenopausal women: a randomized controlled trial. Nutr J 14: 102.

Leger D, Laudon M, Zisapel N. 2004. Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy. Am J Med 116(2): 91-5.

Buscemi N, et al. 2005. The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis. J Gen Intern Med 20(12): 1151-8.

van Geijlswijk IM, Korzilius HP, Smits MG. 2010. The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. Sleep 33(12): 1605-14.

Herxheimer A, Petrie KJ. 2002. Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev (2): CD001520.

Meerlo P, Sgoifo A, Suchecki D. 2008. Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity. Sleep Med Rev 12(3): 197-210.

Trivedi MS, et al. 2015. Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status. PLoS One 12(7): e0181978.

Grander M, Hale L, Moore M, Patel N. 2010. Mortality Associated with Short Sleep Duration: The Evidence, The Possible Mechanisms, and The Future. Sleep Med Rev 14(3): 191-203.

https://www.ncbi.nlm.nih.gov/books/NBK19961/

Bryant PA, Trinder J, Curtis N. Sick and tired: does sleep have a vital role in the immune system?. 2004. Nature Reviews Immunology 4:457-67.

Irwin M, McClintick J, Costlow C, Fortner M, White J, Gillin JC. Partial night sleep deprivation reduces natural killer and cellular immune responses in humans. 1996. FASEB 10:643-53.

Majde JA, Krueger JM. Links between the innate immune system and sleep. 2005. Journal of Allergy and Clinical Immunology 116(6):1188-98.

Opp MR. Sleeping to fuel the immune system: mammalian sleep and resistance to parasites. 2009. BMC Evol Bio 9:8.

Newman A, et al. 1997. Sleep Disturbance, Psychosocial Correlates, and Cardiovascular Disease in 5201 Older Adults: The Cardiovascular Health Study. Jour Am Ger Soc 45(1): 1-7. (ALSO MOOD)

Whitney C, et al. 1998. Correlates of Daytime Sleepiness in 4578 Elderly Persons: The Cardiovascular Health Study. Sleep 21(1): 27-36.

Gottlieb DJ, et all. 2006. Association of Usual Sleep Duration With Hypertension: The Sleep Heart Health Study. Sleep 29(8): 1009-1014.

Sabanayagam C, Shankar A. 2010. Sleep Duration and Cardiovascular Disease: Results from the National Health Interview Survey. Sleep 33(8): 1037-42.

Ge B, Guo X. 2015. Short and long sleep durations are both associated with increased risk of stroke: a meta-analysis of observational studies. Int J Stroke 10(2): 177-84.

Bidulescu A, et al. 2010. Interaction of sleep quality and psychosocial stress on obesity in African Americans: the Cardiovascular Health Epidemiology Study (CHES). BMC Public Health 10: 581.

Leger D, Bayon V, de Sanctis A. 2015. The role of sleep in the regulation of body weight. Mol Cell Endocrin 418 (Pt 2): 101-7.

Grandner M, Jackson N, Gerstner J, Knutson K. 2013. Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample. Appetite (64): 71-80.

Sun W, et al. 2015. Sleep duration associated with body mass index among Chinese adults. Sleep Med 16(5): 612-6.

Copinshi G. 2005. Metabolic and endocrine effects of sleep deprivation.

Ess Psycopharm 6(6): 341-7. {also MEMORY}

Gottlieb DJ, et al. 2005. Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch Intern Med 165(8): 863-7.

Reutrakul S, Van Cauter E. 2014. Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes. Ann N Y Acad Sci 1311: 151-73.

Abel T, Havekes R, Saletin JM, Walker MP. 2013. Sleep, plasticity and memory from molecules to whole-brain networks. Curr Biol 23(17): R774-88.

Nakata A. 2011. Work hours, sleep sufficiency, and prevalence of depression among full-time employees: a community-based cross-sectional study. J Clin Psych 72(5): 605-14.

Watson, AM. 2017. Sleep and athletic performance. Curr Sports Med Rep 16(6): 413-418.

Halson S. 2014. Sleep in Elite Athletes and Nutritional Interventions to Enhance Sleep. Sports Med 44(Suppl 1): 13-23.

Oyetakin-White P, et al. 2014. Does poor sleep quality affect skin ageing? Clin Exp Derm 40(1): 17-22.

Desotelle JA, Wilking MJ, Ahmad N. 2012. The circadian control of skin and cutaneous photodamage. Photochem Photobiol 88(5): 1037-47.

Kavanaua JL. 1997. Origin and Evolution of Sleep: Roles of Vision and Endothermy. Brain Res Bull 42(4): 245-264.

Quant JR. 1992. The effect of sleep deprivation and sustained military operations on near visual performance. Aviat Space Environ Med 63(3): 172-6.

National Sleep Foundation. What Happens When You Sleep?

Mayo Clinic. Is melatonin a helpful sleep aid – and what should I know about melatonin side effects?

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Experience a beautifully balanced-looking complexion with Celavive Resurfacing Serum.

This cutting-edge, science-based formula covers the skin with eight brilliance-boosting ingredients. They work synergistically to refine and brighten without harsh, chemical bleaching agents.

Benefits of using the Celavive Resurfacing Serum:

  • Visibly brightens and evens the appearance of skin tone
  • Reduces the appearance of stubborn skin discoloration for a more even-looking complexion
  • Gently exfoliates to allow for better coverage of brightening key actives
  • Helps reduce the appearance of discoloration

Include Resurfacing Serum in your Celavive Skincare regimen to reveal your skin’s most luminous look.

Banish spots for good and get even with the Celavive Resurfacing Serum. All you’ll see is a perfectly balanced, beautiful complexion.

A Brighter You with Celavive Resurfacing Serum

A flawless, translucent skin tone can be yours with the help of this high-performance serum. Apply Celavive Resurfacing Serum twice daily to reduce the appearance of uneven skin tone.

This advanced serum helps to visibly refine your overall complexion with ingredients that will make visible discoloration virtually disappear. Mandelic acid, Niacinamide, Glycolic acid, peptides, and much more come together to fade the appearance of dark spots and brighten the skin. They work by dispersing the appearance of discoloration on the surface of your skin, making it invisible to the eye. As the pigment is diffused, your skin tone will look bright, even, and flawless.

In only a couple of months, you’ll no longer need to apply heavy concealers or foundation to create a uniform skin tone. But Resurfacing Serum doesn’t just work to make skin look brighter and more even. It helps keep it that way, too.

How to Use Celavive Resurfacing Serum

Celavive Resurfacing Serum can help even out the appearance of your skin tone, reduce dark spots, and give your skin a radiant glow. Here’s a step-by-step guide on how to use Celavive Resurfacing Serum.

  1. Cleanse
    • Use a gentle cleanser to remove dirt, oil, and makeup from your face
      • Creamy Foam Cleanser
      • Gentle Milk Cleanser
      • Postbiotic Calming Cleanser
      • Conditioning Makeup Remover
  2. Tone (Optional)
    • You can apply a toner after cleansing to prepare the skin for better absorption of the serum
  3. Celavive Resurfacing Serum
    • Apply a pea-sized amount of serum. It is concentrated so a little goes a long way.
    • Gently pat the serum into your face and neck using your fingertips. Avoid rubbing too hard as this can irritate the skin
    • Give the serum a couple minutes to absorb into the skin before applying other products
  4. Moisturize
    • Follow up with a moisturizer to lock in the serum and hydrate your skin
      • Protective Day Cream SPF 30
      • Protective Day Lotion SPF 30
      • Replenishing Night Cream
      • Replenishing Night Gel
      • Postbiotic Soothing Moisturizer

By following these steps, you’ll effectively incorporate Celavive Resurfacing Serum into your skincare routine and enjoy a more radiant complexion.

What Causes Skin Discoloration?

Melanin is the pigment made in the top layer of your skin that’s the source of your skin color. Beyond that, its main role is protecting your skin by absorbing ultraviolet (UV) rays.

The types and amounts of melanin made in your skin can vary. They are controlled by your genes and can be influenced by internal and external factors, such as age, hormones, and environmental stressors like exposure to UV light.

Too much sunlight is one of the major causes of excess melanin production. With more and more sun exposure, a pocket of concentrated melanin can form that extends deep within your skin. This can show up as a dark spot or as blotchy, uneven skin tone. This hyperpigmentation usually appears on the face, arms, hands, chest—any areas regularly exposed to the sun.

Usually, discoloration, age spots, and uneven skin tone are perfectly safe (just make sure to ask your doctor about large, irregularly shaped spots that are very dark or have multiple colors). But you may dislike how it looks and want a solution.

Because the concentrated melanin extends more deeply into your skin layers, it can’t simply be scrubbed away. It takes consistent use of effective topical products to fade the appearance of discoloration as your skin cells renew over time. And constant protection from the sun is required to maintain skin’s brightness and translucence.

Noteworthy Ingredients:

Niacinamide 2%

There are many ingredients that can lighten the skin’s appearance. Some of the most common are hydroquinone, retinoids, and azelaic acid. However, these may cause skin sensitivity and irritation.

There is a gentler option that’s been well-studied and found to be effective for refining the skin’s appearance. It’s a form of vitamin B3 called niacinamide (also known as nicotinamide).

Niacinamide is a key ingredient of Celavive Resurfacing Serum. Topical application of this vitamin soothes and moisturizes as it helps visibly balance skin tone and boost radiance. Clinical trials have shown it can reduce the appearance of discoloration, when used twice a day.

One study included 18 subjects with hyperpigmentation who used a five percent niacinamide moisturizer and plain moisturizer in a paired design. There was noticeably less visible pigmentation and increased luminosity in the niacinamide group after four weeks.

A second study of 50 women, ages 40 to 60, found that a five percent niacinamide cream provided significant improvements in the appearance of hyperpigmentation, skin tone, and texture after 12 weeks.

Skin brighteners tend to work best when used in combination. In addition to niacinamide, Celavive Resurfacing Serum contains unique ingredients that will help further reduce the appearance of discoloration and beautifully balance your complexion.

Mandelic Acid

Alpha hydroxy acids (AHA) are often used in skincare to smooth visible fine lines and wrinkles and improve skin tone appearance. Mandelic acid is a type of AHA originally derived from almonds. Its molecular structure is larger than other AHA’s, which slows down its penetration into the skin compared to other AHA’s. This slower penetration significantly lowers its irritation potential to the skin, making this a very gentle ingredient suitable for sensitive skin.

In this formula, Mandelic Acid helps conceal the appearance of acne, blemishes, dark spots, fine lines, and wrinkles.

Acetyl Tetrapeptide-40

Telangyn is an innovative peptide complex designed to reduce visible redness in the skin. Peptides are used in skincare, especially for sensitive skin. They also have high potency and efficacy even at a low dosage.

This peptide complex also targets telangiectasia, which refers to the small blood vessels or spider veins that can appear on the skin. Telangiectasia is harmless but may not be very appealing to have on your face.

Telangyn peptide complex helps conceal hyperpigmentation, the appearance of redness and dilated blood vessels, and improves skin tone.

Nonapeptide-1

Nonapeptide-1 is a peptide designed to reduce dark spots, even out skin tone, and conceal the appearance of skin spots related to the hyperproduction of melanin. It doesn’t interfere with the natural function of your melanocytes and therefore doesn’t cause any damage to your cellular function, making it an ideal ingredient to support the appearance of the skin.Glycolic & Lactic Acids

Glycolic and Lactic acids are are a potent exfoliant for the skin. They help to remove dead skin cells and reveal smoother, brighter skin. They are designed to help diffuse AHA’s onto the surface of the skin in a controlled and balanced way. Thes ingredients boost exfoliation without irritating the skin.

Bakuchiol 1%

Retinol and retinoids have been used to counter the visible effects of premature aging from UV radiation (sunlight). The problem with retinol is that it can sometimes be poorly tolerated by the skin and cause irritation. Bakuchiol oil is an alternative that doesn’t have any of the negatives associated with Retinol. Bakuchiol is a phytochemical compound derived from Psoralea corylifolia, a plant historically used in Indian and Chinese traditional medicine.

Research has shown that Bakuchiol may help conceal hyperpigmentation and wrinkles as efficiently as retinol without side effects.

In this formula, Bakuchiol helps calm visible redness. The antioxidants in the extract help support the look of firmer skin, with fewer lines and wrinkles. And they keep existing discoloration from looking darker after sun exposure. Overall, Bakuchiol oil aids in overall skin health and radiance.

White Willow Bark 5%

Salicin, a natural source of salicylic acid, is extracted from white willow bark and has been researched for its wide-spectrum benefits for the skin.

In one clinical study, salicin was found to improve the appearance of wrinkles, roughness, pore size, radiance, and overall appearance in as little as one week.

See full list of ingredients

Frequently Asked Questions

Yes, you can use these two serums in conjunction. We recommend using Resurfacing Serum first and then applying Vitalizing Serum or using these serums alternatively, one in the AM and the other in the PM or swapping them out nightly.

We recommend applying it twice daily: morning and night. If the serum is too tacky or sticky for morning use, then continue to use nightly. For daytime use, always follow with sunscreen when using this product as photo sensitivity may occur.

We do not recommend use of this product while pregnant.

With daily, regular use the 50 ml bottle should last about 6 weeks.

Some of the ingredients may make your skin more sensitive to sunlight. SPF protects your skin from harmful exposure to UV rays, and preserves the integrity of the ingredients of the serum.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10304091/

https://pubmed.ncbi.nlm.nih.gov/16766489/

https://pubmed.ncbi.nlm.nih.gov/31553119/

https://www.deascal.com/ingredient-information/acetyl-tetrapeptide-40/

https://pubchem.ncbi.nlm.nih.gov/compound/Nonapeptide-1

https://www.health.harvard.edu/staying-healthy/bakuchiol-does-it-make-skin-look-younger

https://pubmed.ncbi.nlm.nih.gov/25997859/

USANA Health Sciences offers the highest quality products you can find anywhere. To guarantee their quality, USANA products are manufactured under rigorous conditions, and each product goes through four major areas of testing: Purity, Identity, Composition, and Strength. This ensures that you can be confident in USANA’s products, and that what’s on the label is in the product.

The quality control process is unique for each product and each raw material. USANA’s Research and Development team custom designs the testing necessary for each individual product and ingredients. Hepasil DTX is just one of USANA’s many high-quality products. Below you will find some of what goes into guaranteeing the quality of this product.

Hepasil DTX Testing for Purity, Identity, Composition, and Strength

Item Tested Purity Identity Composition Strength Strength Dosage Third-Party Validated
Hepasil DTX Tablet ✅ ✅ ✅ ✅ ✅ ✅
Biotin ✅ ✅ ✅ ✅ 75 µg ✅
Choline ✅ ✅ ✅ ✅ 51.3 mg ✅
Milk Thistle Extract ✅ ✅ ✅ ✅ 80 mg ✅
N-Acetyl L-Cysteine ✅ ✅ ✅ ✅ 75 mg ✅
Alpha-Lipoic Acid ✅ ✅ ✅ ✅ 67 mg ✅
Broccoli Concentrate ✅ ✅ ✅ ✅ 25 mg ✅
Inositol ✅ ✅ ✅ ✅ 25 mg ✅
Green Tea Extract ✅ ✅ ✅ ✅ 15 mg ✅
Olivol ✅ ✅ ✅ ✅ 15 mg ✅
Meriva Curcumin ✅ ✅ ✅ ✅ 1.33 mg ✅

Purity

Supplements are designed to nourish your body and support your health, not harm it. Just how food can become contaminated without proper food safety, ingredients in your supplement can be contaminated too. Potential contamination becomes especially critical in supplement raw materials. That’s because extraction and concentration of beneficial components can concentrate the harmful ones too.

Testing of raw ingredients and the finished product is essential to make sure that you won’t be harmed by biological contaminants, heavy metals, pesticides, and other forms of contamination.

Hepasil DTX Biological Contamination Testing Specifications

Total plate count: ≤ 3000 CFU/gram (10,000 CFU/gram milk thistle)

Escherichia coli: Absent in 10 g sample

Salmonella species: Absent in 10 g sample

Staphylococcus aureus: Absent in 10 g sample

Total molds and yeast: ≤ 300 CFU/gram

Hepasil DTX Chemical Contamination Testing Specifications

Lead: ≤ 1.71 ppm

Arsenic: ≤ 5.15 ppm

Mercury: ≤ 5.15 ppm

Cadmium: ≤ 1.71 ppm

Solvents Tested: Acetonitrile, Benzene, Carbon tetrachloride, Chlorobenzene, Chloroform, Cumene, Cyclohexane, 1,2-Dichloroethane, 1,1-Dichloroethene, 1,2-Dichloroethene, 1,2-Dimethoxyethane, N,N-Dimethylacetamide, N,N-Dimethylformamide, 1,4-Dioxane, 2-Ethoxyethanol, Ethylene glycol, Formamide, Hexane, Methanol, 2-Methoxyethanol, Methylbutylketone, Methylcyclohexane, Methylene chloride, Methylisobutylketone, N-Methylpyrrolidone, Nitromethane, Pyridine, Sulfolane, 1,1,1-Trichloroethane

Residual Solvents Test Specifications: Tested to conform with USP standards for each individual solvent.

Pesticides Tested: Acephate/Orthene, Alachlor, Alachlor, Aldrin, Azinphos ethyl, Azinphos methyl/Gluthion, BHC Total, BHC Alpha, BHC Beta, BHC, delta, BHC gamma/Lindane, Bromophos ethyl, Bromophos methyl, Bromopropylate/Acarol, Chlordane (total), Chlordane alpha, Chlordane gamma, Chlordane Oxy, Chlorfenvinphos, Chlorpyrifos/Dursban, Chlorpyrifos Methyl, Chlorthal-Dimethyl/Dacthal, Cyfluthrin (Sum), Cyhalothrin Lambda, Cypermethrin (sum of isomers), DDD-2,4’/DDD-o,p’, DDD-4,4’/DDD-p,p’, DDE-2,4’/DDE-o,p’, DDE-4,4’/DDE-p,p’, DDT, Total, DDT-2,4’/DDT-o,p’, DDT-4,4’/DDT-p,p’, Deltamethrin, Diazinon, Dichlofluanid, Dichlorvos/DDVP, Dicofol-o,p’, Dieldrin, Dimethoate/Cygon, Dithiocarbamates (CS2), Endosulfan (total), Endosulfan I, Endosulfan II, Endosulfan sulfate, Endrin aldehyde, Ethion, Endrin ketone, Ethion, Etrimfos/Etrimophos, Fenchlorphos/Ronnel, Fenchlorphos-oxon, Fenitrothion, Fenpropathrin, Fensulfothion (Sum), Fensulfothion-oxon, Fensulfothion-oxon sulfone, Fensulfothion-sulfone, Fenthion/Baytex, Fenthion sulfone, Fenthion sulfoxide, Fenthion-oxon, Fenthion-oxon sulfone, Fenthion-oxon sulfoxide, Fenvalerate/Sanmarton, Ferbam, Flucythrinate, Fluvalinate, tau, Fonofos/Dyfonate, Heptachlor, Heptachlor epoxide, Heptachlor epoxide A, Heptachlor epoxide B, Hexachlorobenzene/HCB, Malaoxon/Malathion OA, Malathion, Mancozeb, Maneb, Mecarbam, Methacrifos, Methamidophos, Methidathion/Supracide, Methoxychlor, Mirex, Monocrotophos/Azodrin, N-Desethyl-Pirimiphos-methyl, Nabam, Omethoate, Parathion, Parathion Methyl/Methyl Parathion, Parathion Methyl Oxon, Parathion Oxon/Paraoxon, Pendimethalin/Prowl, Pentachloroaniline, Pentachloroanisol/PCA, Pentachloronitrobenzene/PCNB/Quintozene, Pentachlorothioanisole/Methyl pentachlorophenyl sulfide/MPCPS, Permethrin/Pounce, Permethrin, cis, Permethrin, trans, Phosalone/Zolone, Phosmet/Imidan, Piperonyl Butoxide, Pirimiphos ethyl, Pirimiphos methyl ,Procymidone, Profenophos/Curacron, Propineb, Prothiofos/Tokuthion, Pyrethrin/Pyrethrum, Pyrethrin I, Pyrethrin II, Quinalphos, Thiram, Zineb/Metiram, Ziram

Pesticides Test Specifications: Tested to conform with USP standards for each individual pesticide.

Identity

Identifying the beneficial components of the finished good and each raw material is the next step of the quality control process.

Following manufacturing, every batch is reviewed and approved to meet good manufacturing practices and product specifications for each raw material and the finished good. The identity for each raw material within the product must meet the identity specified on the product label.

For raw materials, each batch of raw material is sampled, inspected, and analytically tested. They’re tested to ensure that the raw material contains the desired nutrients in the right form and concentration.

Each raw material has its own specific testing procedure and method. An overview of the test method and a sample method for Meriva Curcumin can be found below.

Ingredient Test Method
Biotin LCMS
Choline LCMS
Milk Thistle Extract HPTLC and HPLC
N-Acetyl L-Cysteine HPLC and FTIR
Alpha-Lipoic Acid HPLC
Broccoli Concentrate FTIR
Inositol LCMS
Green Tea Extract HPTLC
Olivol HPTLC
Meriva Curcumin HPLC

LCMS = Liquid Chromatography Mass Spectroscopy

HPTLC = High Performance Thin Layer Chromatography

HPLC = High Pressure Liquid Chromatography

FTIR = Fourier Transform Infrared Spectroscopy

Test Methodology Example: Meriva Curcumin

  1. Prepare 0.03% formic acid
  2. Prepare solvent solution MeOH:DMSO (75%:25%)
  3. Prepare HPLC
    1. Install HPLC column
    2. Purge with formic acid
    3. Turn on detector and start flow with 65% formic acid and 35% methanol.
  4. Prepare standard sample by mixing reference curcumin and solvent (from step 2)
  5. Prepare raw material sample by mixing sample curcumin with solvent (from step 2)
  6. Load vials into HPLC sampler and start run. Total run time is 12.3 minutes.
  7. Collect data and calculate results.

Example HPLC Output

Composition

Each ingredient has its own composition that is tested and verified by USANA before it can be used in manufacturing. For example, milk thistle has a huge number of different components in the plant, and those could be found in a variety of different proportions within a raw material. Silymarin is the primary component of interest by USANA scientists when they designed this product. So, the milk thistle used in Hepasil DTX is verified to have a composition of 80% silymarin.

The milk thistle extract is also reviewed for other beneficial components, source location, and potential allergens. A similar analysis is performed for every raw material used in Hepasil DTX.

Tablet composition is important to make sure that your body can digest the tablet, and that individual nutrients reach and benefit your cells. This starts with the research and development process, where the product is formulated. The active ingredients aren’t the only important part of a tablet. Additional ingredients must be added to make everything form into a solid and durable tablet, but also one that can be easily broken down in the body.

After the right combination of ingredients is determined, the tablet can finally go into production. Every finished batch of product is analyzed and tested for weight, thickness, disintegration, friability (tendency to break), and hardness.

Hepasil DTX Composition

Appearance: Hepasil DTX is a coated Bi-Layer tablet. One layer is white to off white; the other layer is tan to beige. Some color variation is normal.

Weight: 980 mg

Thickness: 6.6 mm

Disintegration: 100% disintegration in ≤ 20 minutes

Strength

Finally, finished products are tested to have the strength and potency guaranteed on the labels—one of the main reasons why people trust their health to USANA. This requires repeating many of the purity tests from the individual tests from the identification step above. Adjustments are made to the methods as needed, due to differences between a finished good and raw materials.

Stability testing is also performed to guarantee the potency of the product throughout shelf-life.

Long-Term Product Stability

Vitamins, plant compounds, and other nutrients can oxidize and degrade over time. Over time, this can result in the level of these nutrients being lower than the amount listed on the level. However, a properly formulated product helps to counteract this risk and guarantee the viability of the product throughout its shelf-life. This includes meeting at least 100% label claim throughout shelf-life.

Long-term stability testing is necessary to test product formulation. This ensures that there are no significant physical, chemical, or microbiological changes to the Hepasil DTX Bi-Layer tablet that would negatively impact its beneficial properties for the consumer.

Stability studies are conducted on Hepasil DTX following guidelines set forth by the U.S. FDA, Canada NHPD, Australia’s TGA, and the ICH. The product is tested for potency and purity at the date of manufacture, then samples are placed in a controlled test environment. The test environment is maintained at 25 ± 2 °C and 60 ± 5% relative humidity throughout the shelf-life of the product (24 months from the date of manufacture).

Samples are pulled from the stability batch at 12 and 24 months. Potency of the active ingredients is tested at both of these intervals, and the 24-month sample is tested for biological contamination.

Government and Third-Party Validation

A tremendous amount of research goes into formulating, manufacturing, and testing each USANA product. You don’t have to take our word for it though. USANA facilities and manufacturing processes are regularly audited by outside organizations, finished products have a variety of certifications, and products are studied in collaboration with research organizations around the world.