Build Your Foundation for Health with USANA® CellSentials™
The CellSentials are so much more than your average multivitamin. Each daily dose provides essential vitamins, minerals, antioxidants, plus additional key nutrients. The exclusive InCelligence Complex, made using USANA’s patent-pending USANA InCelligence Technology®, goes beyond nourishing the body. It also helps activate your body’s natural ability to respond to stress and keep your cells healthy.*
The CellSentials are formulated to meet the needs of generally healthy adults of any age who eat a balanced diet. They offer excellent nutritional support for the entire body:*
- Immune system
- Cardiovascular system
- Skin and nails
- Cell health and integrity
- Nervous system
- Bones and joints
- Muscle and tissue
- Metabolism and energy
The combination of Vita Antioxidant and Core Minerals delivers results you can feel. After one month of taking the CellSentials, an in-house USANA study found that participants self-reported perceived benefits in their mental and physical health, as well as vitality.*
Each tablet has readily bioavailable forms of each nutrient. This is important because your body can’t use what it can’t absorb.
And every USANA product is made to the highest standards. So, you can trust the CellSentials will have excellent completeness, potency, purity, and safety. For easy swallowing, the Core Minerals and Vita Antioxidant tablets have a sunflower-based coating.
Support your overall health with the CellSentials—a strong nutritional foundation you can build on.*
- 1 Your Best Health Starts with a Better Supplement
- 2 The USANA CellSentials are Made with Smart Supplement Design
- 3 Nourish Your Cellular Health with Optimal Amounts of Essential Nutrients
- 4 Core Minerals
- 5 Vita Antioxidant
- 6 Build Cellular Resilience and Longevity with the InCelligence Complex
- 7 Protect Your Cellular Health with Powerful Antioxidant Defense
- 8 Renew Your Health by Supporting Youthful Cellular Function
- 9 Frequently Asked Questions About USANA CellSentials
Vibrant health starts with well-nourished cells. And there’s a reason an estimated eight out of 10 people take supplements: it’s not always easy to eat right. Statistics continue to show that most people need to supplement. Their daily diet simply doesn’t supply even the minimum recommended amounts of many vitamins and minerals. And even if you could design a nutritionally perfect set of meals and snacks, would you eat that same food every day?
Like a nutritional “insurance plan,” a good daily supplement can help fill in the gaps. So, the question becomes, what is a good daily supplement?
Take a trip down the aisles of your local market. The choices for daily supplements can be daunting. You could choose a gummy that’s tasty (and probably laced with sugar) or a one-a-day multi. Either choice might provide enough of a basic set of micronutrients to avoid a deficiency. But you likely won’t get the range or levels of nutrients you need to achieve optimal health.
You see, there’s a difference.
Nutritional authorities often establish the recommended nutrient levels on supplement labels based on what it takes to avoid deficiency. (This is referenced as %DV—Percent of Daily Value—on labels in the United States.) The amounts aren’t at levels research shows can help make a difference in your long-term health.
To illustrate the differences, here’s a couple examples:
- The Food and Nutrition Board of the Institutes of Medicine set a Recommended Dietary Allowance (RDA) for vitamin D of 600 IU/day or 15 mcg. However, research has shown you often need higher levels to achieve the blood levels needed for good health. In fact, a 2011 in-house study conducted at USANA found that supplementation of up to 5,000 IU was necessary to reach optimal levels (40-60ng/mL). (Labels in the United States now list vitamin D amounts in micrograms. 5000 IU equates to about 125 mcg per day.)
- The current RDA for vitamin B12 is 2.4 mcg/day. However, some research has shown that up to 500 mcg had positive effects on homocysteine levels in the body—when combined with .5-5 mg of folic acid. Homocysteine is an amino acid that is measured as a marker of heart health.
That’s not all. Another consideration in your supplement selection is the ratio of nutrients used together. It can be tempting to pick and choose your nutrients. But those nutrients might be affected by others. For instance, iron and copper work better together. You need enough of one for the other to be used correctly in the body. Calcium, too, requires adequate levels of magnesium, vitamin K, and vitamin D to maintain healthy bones. The relationships between nutrients can be complex.
A well-designed multivitamin and mineral supplement is made with an understanding of the complexities. It provides you with the right amounts and the right balance of nutrients. And those nutrients are delivered in forms that can be used by the body. That’s where the USANA CellSentials come in.
Vita Antioxidant and Core Minerals support good health with a broad range of premium-quality micronutrients. When taken together, you get a carefully formulated balance of four key types of nutrients to nourish, protect, and renew your cells:
- Essential vitamins, minerals, and trace minerals that nourish cellular health*
- Other beneficial building blocks and substances (often called cofactors) your body needs to use vitamins and minerals effectively*
- Dietary phytonutrients and antioxidants to defend against oxidative stress*
- Targeted nutrients that can act like cell signaling molecules to help promote the body’s natural health protection and renewal reactions*
Adding the CellSentials to a varied diet will help ensure you consume the right amounts of key nutrients. You will have a great foundation to help support vibrant health every day. When taken for one month, the CellSentials have been shown to increase circulating blood levels of many nutrients known to be beneficial for health.*
The CellSentials go beyond simply supporting good health with nutrients. They also help activate some of your cells’ responses that can keep you healthy with InCelligence Technology. These responses promote youthful cellular function, so your body can adapt to your unique lifestyle needs and help you age well.*
Your cells need the right ingredients to maintain health. That includes the nutrients needed to help them (and you) thrive. Support the health and longevity of your cells with an essential foundation of optimal nourishment. Core Minerals and Vita Antioxidant are designed to work together to support whole body health.*
Your lifestyle is unique. Your diet, activity levels, environment, sleep patterns, and stress levels all bring unique challenges to the health and integrity of your cells. You can help your cells adapt to those unique needs. Start with the healthy foundation of nutrition your cells need to function in the CellSentials. Then help build cellular resilience with the InCelligence Complex.*
The InCelligence Complex in Vita Antioxidant is a powerful blend of ingredients that supports a network of cell-signaling pathways. These pathways help cells adapt and respond to whatever life throws at them.*
The CellSentials deliver a number of dietary antioxidants to provide a first layer of defense against cell-damaging free radicals. But your body is made of trillions of cells that need protection. So, dietary antioxidants (also known as exogenous antioxidants) may not be enough.*
What if you could help your cells protect themselves?*
Your cells are naturally equipped with powerful antioxidants. Molecules such as superoxide dismutase, catalase, and glutathione are made in your cells. The nutrients in the InCelligence Complex help proactively stimulates production of these natural protectors.*
It’s simple math. Dietary antioxidant molecules neutralize free radicals in a one-to-one or one-to-two ratio: one dietary antioxidant eliminates one or two free-radical molecule(s). Endogenous antioxidants are typically able to neutralize 100 or more free-radical molecules during their lifespans. By encouraging the production of your natural antioxidants, the InCelligence Complex helps deliver significantly more protection. It is a powerful way to defend against an imbalance of the oxidative stress that can damage your healthy cells.*
Learn more about the antioxidant cell signaling pathway targeted by the InCelligence Complex
Your cells innately know how to protect themselves from damaging free radicals. A key controller of this cellular defense mechanism is the Nrf2 (nuclear factor erythroid 2–related factor 2)-antioxidant response element (ARE) pathway. When a cell senses an oxidant, also known as a free radical, it activates Nrf2. This begins a complex cascade of events that ultimately results in antioxidants being released by the cell. Certain chemicals, including those found in the InCelligence Complex, support stimulation of the Nrf2-ARE pathway to proactively promote antioxidant production.*
Your cells produce energy (ATP—adenosine triphosphate) in the mitochondria. This cellular energy production also generates a lot of free radicals. Natural antioxidants in the cell neutralize many of the free radicals. But some mitochondria will still be damaged over time. Damaged mitochondria can work inefficiently, producing less ATP and more damaging free radicals. This causes a self-perpetuating cycle of damage.*
The cell maintains efficiency through a natural response called mitophagy. Think of it like taking out the trash. Or cellular quality control. Initiating mitophagy degrades, removes, or recycles the damaged mitochondria. So, they aren’t causing damaging reactions and the cell stays healthy. However, age or other lifestyle factors may slow this process. The InCelligence Complex helps activate mitophagy to renew efficient energy production and keep cells acting youthful.*
Learn more about the mitophagy cell signaling pathway targeted by the InCelligence Complex
A cell works just like an engine—it works better when it’s clean than when it’s dirty. The mammalian target of rapamycin (mTOR) signaling pathway is a key regulator of cell metabolism, growth, and survival. It controls autophagy—a cleanup process that gathers and breaks down proteins in the cell.
Mitophagy is a type of autophagy specific to mitochondria. When the cell has limited availability of nutrients, as in the case of caloric restriction, mTOR initiates mitophagy. After proteins are degraded, the mitochondria can use those proteins to help fuel the process needed to create ATP—cellular energy.
When nutrients are abundant (i.e., when you’re eating regularly), mTOR reduces autophagy because the cells have plenty of fuel. So, they don’t need to be as efficient. The compounds found in the InCelligence Complex can cause cellular responses that mimic those caused by caloric restriction. This can start the cellular housekeeping process that helps keep your cells efficient, but you don’t have to eat less.*
Frequently Asked Questions About USANA CellSentials
Why are there so many tablets in the CellSentials?
It is simply not possible to condense the nutrient amounts in the CellSentials into fewer tablets. For example, if USANA provided the full CellSentials dosage in one pill, the tablet would be so large it would be like swallowing a golf ball. If nutrient amounts in the CellSentials were reduced to levels appropriate for a single tablet dose, nutrient amounts would have to mimic Centrum® or One-A-Day®, with minimal antioxidants, strictly RDA levels of vitamins, and very little in the way of minerals. Higher nutrient amounts require space, and unfortunately there are limits to what can be condensed into a single tablet.
Why don’t the CellSentials contain iron?
USANA’s CellSentials do not contain iron. The widespread availability of iron-fortified foods ensure that most adults receive sufficient iron from their diets (as a common example, just one cup of a popular toasted oat cereal provides 45% of the RDA for iron).
Iron supplementation is best handled separately by those who specifically need it. One such group includes pregnant women, who can get the benefits of the CellSentials plus iron in the Prenatal CellSentials.
Are there potential side effects associated with taking the CellSentials?
During the premarketing evaluation of the CellSentials, and the Sanoviv Medical Institute trial participants were asked to report any unexpected reaction both positive and negative as a consequence of consuming the Cellsentials. The lack of any significant adverse events demonstrates that the new Cellsentials are generally safe and well-tolerated in healthy people. If you have a medical condition or if you are taking prescription medications we strongly suggest that you consult with your healthcare provider and pharmacist to determine if the CellSentials are appropriate for you to take.
Can the CellSentials cause my skin to turn yellow?
Hypercarotenemia is a benign temporary yellowing of the skin caused by consuming large amounts of beta-carotene. The amount necessary to cause this type of condition, regardless of the weight of the individual, far exceeds the amount contained in the daily dose of the CellSentials. The amount of beta-carotene in a daily dose of the Vita Antioxidant is similar to the amount of beta-carotene obtained from one small carrot. Eating one carrot per day won’t cause hypercarotenemia.
If, however, someone is regularly juicing vegetables or consuming large quantities of vegetables high in beta-carotene (in addition to taking the CellSentials), it may be possible to develop hypercarotenemia.
Age-Related Eye Disease Study Research Group. A randomized, placebo controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. 2001. Arch Ophthalmol 119(10): 1417-36.
Barringer TA, Kirk JK, Santaniello AC, Foley KL, Michielutte R. Effect of a multivitamin and mineral supplement on infection and quality of life. A randomized, double-blind, placebo-controlled trial. 2003. Ann Intern Med 138(5):365-71.
Girodon F, Galan P, Monget AL, Boutron-Ruault MC, Brunet-Lecomte P, Preziosi P, Arnaud J, Manuguerra JC, Herchberg S. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial. 1999. Arch Intern Med 159(7):748-54.
Heinrich U, Gartner C, Wiebusch M, Eichler O, Sies H, Tronnier H, Stahl W. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. 2003. J Nutr 133(1):98-101.
Meydani SN, Meydani M, Blumberg JB, Leka LS, Siber G, Loszewski R, Thompson C, Pedrosa MC, Diamond RD, Stollar BD. Vitamin E supplementation and in vivo immune response in healthy elderly subjects: a randomized controlled trial. 1997. JAMA 277(17):1380-6.
Placzek M, Gaube S, Kerkmann U, Gilbertz KP, Herzinger T, Haen E, Przybilla B. Ultraviolet B-induced DNA damage in human epidermis is modifed by the antioxidants ascorbic acid and D-alpha-tocopherol. 2005. J Invest Dermatol 124(2):304-7.
Why Trace Minerals? Trace Minerals Research [Internet] [accessed 12 Feb 18] Available at https://traceminerals.com/why-trace-minerals/
Watts D. Nutrient Interrelationships: Minerals — Vitamins — Endocrines. Orthomolecular.org [Internet] [accessed 12 Feb 18] Available at http://www.orthomolecular.org/library/jom/1990/pdf/1990-v05n01-p011.pdf
Pizzino G, et al. 2017. Oxidative stress: harms and benefits for human health. Oxid Med Cell Long [Internet] [accessed 5 Mar 18] Available at https://www.hindawi.com/journals/omcl/2017/8416763/
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*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.