In a study published in the Archives of Internal Medicine, over 19,000 men were recruited to determine the relationship between cardiorespiratory fitness (CRF) and mortality risk in healthy men and those with metabolic syndrome. The study group, which included about 3,800 men with metabolic syndrome, were evaluated for fitness and then followed for up to 17 years.

Healthy men who were out of shape at the beginning of the study were three times as likely as their fit peers to die of cardiovascular disease. While men with metabolic syndrome were 89 percent more likely than healthy men to die of heart disease over the years, men with metabolic syndrome who were unfit had twice the death rate as their fit counterparts.

According to the researchers, “This study strengthens the argument for aggressive public health campaigns aimed at increasing physical activity levels in the population.”  Fitness, regardless of body weight, can provide a strong protective effect against premature death in men with metabolic syndrome as well as healthy men.

Arch Intern Med 2004 May 24;164(10):1092-7

A study conducted at Duke University and published in the journal Chest compared the effects of three different exercise regimens on fitness improvements in overweight men and women who were at risk for heart disease.

Broken into four groups, the volunteers either did not exercise, walked briskly for 12 miles a week at a moderate intensity, walked briskly or jogged slowly 12 miles a week at a vigorous intensity, or jogged 20 miles a week at a vigorous intensity.

Two measurements of fitness – time to exhaustion and oxygen consumption – were measured before and after 7 to 9 months of training.

All exercise groups saw fitness improvements compared to baseline. Results indicated that two to three hours of mild exercise a week at a moderate intensity is sufficient to increase aerobic fitness and cut the risk of cardiovascular disease. Increasing either the intensity or the amount of exercise provided additional improvements in fitness.

Although more vigorous exercise should still be encouraged for maximum benefit, this study demonstrates that it is appropriate to recommend mild exercise to improve fitness levels and reduce cardiovascular disease risk, especially in those who are overweight and sedentary.

Chest. 2005;128:2788-2793.