Tag Archive for: vitamins and supplements

In research published in the International Journal of Obesity, scientists evaluated the effects of multivitamin/mineral supplementation on body fat, energy expenditure, and lipid profiles in obese Chinese women. Subjects were divided into three groups, receiving either a multivitamin/mineral supplement (MMS), 162mg of calcium, or placebo daily. Body weight, BMI, waist circumference, fat mass, lean tissue, resting energy expenditure, blood pressure, fasting plasma glucose and serum insulin, total cholesterol, LDL and HDL cholesterol, and triglycerides were measured at the beginning and end of the study period.

After 26 weeks, the multivitamin/mineral group had significantly lower body weight, BMI, fat mass, total and LDL cholesterol, and significantly higher resting energy expenditure and HDL cholesterol than individuals in the placebo group. They were also more likely to have a reduced waist circumference. The calcium group also had significantly higher HDL cholesterol and lower LDL cholesterol levels compared with the placebo group.

The results suggest that multivitamin/mineral supplementation could help reduce body weight and obesity and improve serum lipid profiles in obese women, possibly through increased energy expenditure and fat oxidation.

The correlation between inadequate nutrient status and obesity was further strengthened in a new study involving mice. For 12 weeks, mice were given either a standard diet or one that was restricted to 50% of their micronutrient requirements. At the end of the study, the body weight of the mice with a nutrient restricted diet was 6% higher than the controls, and their body fat more than doubled.

The results of a clinical trial published in Arthritis Research and Therapy suggest that supplementing with glucosamine and taking regular walks can improve pain, physical function, and overall activity levels in adults with mild to moderate knee or hip osteoarthritis.

Thirty-six low-activity participants (aged 42 to 73 years) were provided with 1500 mg glucosamine sulfate per day for 6 weeks. At the end of six weeks, the participants began a 12-week progressive walking program (while continuing to take glucosamine.)

Study subjects were given a pedometer to monitor step counts. They were then randomized into two groups – one to walk 3 days per week, the other to walk 5 days per week. The length of the walk was gradually increased over the course of the program, with 6000 per day being the goal by the end of the 12-week period. Physical activity levels, physical function, and arthritis symptoms were analyzed at the beginning and at 6, 12, 18 and 24 weeks.

Physical activity levels, physical function, and pain assessment scores improved during the first 6 weeks of the study (glucosamine supplementation only.) Between the start of the walking program (week 6) and the final follow-up (week 24), further improvements were seen, though most improvements happened between weeks 6 and 12. No significant differences were observed between participants who participated in the 3 and 5 day per week programs.

In people with mild to moderate hip or knee osteoarthritis, walking a minimum of 3,000 steps (approximately 30 minutes) at least 3 days per week, in combination with glucosamine sulfate, may reduce some symptoms of osteoarthritis.

Ng N, et al. Efficacy of a progressive walking program and glucosamine sulphate supplementation on osteoarthritic symptoms of the hip and knee: a feasibility trial. 2010. Arthritis Research & Therapy 12(1):R25.