Tag Archive for: essential nutrients

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osteocalcin

In addition to Calcium, Magnesium and Vitamin D, vitamin K1 and K2 play an essential role in bone health by regulating levels of osteocalcin. Osteocalcin is a protein found in the extracellular matrix of bone and dentin that is involved in regulating mineralization in the bones and teeth. A study published in Calcified Tissue International […]

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Post-menopausal women are more susceptible to osteoporosis as their estrogen levels decline. This leads to greater excretion of calcium and results in more brittle bones prone to fracture. In this study, women who took calcium supplements twice a day reduced their risk of breaking a bone, but getting them to consistently take the supplements was a problem.

The study, published in the Archives of Internal Medicine, led researchers to state that they believed calcium supplementation may not be a good public health approach to fracture prevention, not because they don’t work, but because of the lack of long-term compliance. Nearly half the 1,460 healthy women who participated in the study did not consistently take the twice-daily 600 mg supplements.

However, among the women in the study who took at least 80 percent of their assigned calcium, only 10 percent suffered a fracture within one year compared to 15 percent of the women who regularly took a placebo. Therefore, taking extra calcium in supplement form did significantly help those women who took them regularly.

The results of this study illustrate two important points: negative conclusions reported in some supplement studies may be a result of poor compliance, not the failure of the supplement itself, and supplements won’t likely be effective if they are not taken consistently.

Prince RL, Devine A, Dhaliwal SS, Dick IM. Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women. Archives of internal medicine. 166(8):869-75. 2006.

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