{"id":9878,"date":"2017-06-26T08:30:12","date_gmt":"2017-06-26T14:30:12","guid":{"rendered":"https:\/\/askthescientists.com\/qa\/liver-detoxification-pathways\/"},"modified":"2022-07-05T10:17:37","modified_gmt":"2022-07-05T16:17:37","slug":"liver-detoxification-pathways","status":"publish","type":"qa","link":"https:\/\/askthescientists.com\/zh-hant\/qa\/liver-detoxification-pathways\/","title":{"rendered":"\u809d\u81df\u89e3\u6bd2\u8def\u5f91"},"content":{"rendered":"<p><img decoding=\"async\" class=\"aligncenter size-large wp-image-8718\" src=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-835x486.jpeg\" alt=\"liver detoxification\" width=\"835\" height=\"486\" srcset=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-835x486.jpeg 835w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-400x233.jpeg 400w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-768x447.jpeg 768w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-705x411.jpeg 705w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-450x262.jpeg 450w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159.jpeg 1200w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><\/p>\n<p>\u809d\u81df\u662f\u91cd\u8981\u5668\u5b98\uff0c\u5b83\u6703\u5728\u4ee3\u8b1d\u3001\u6d88\u5316\u3001\u80fd\u91cf\u5132\u5b58\u3001\u548c\u8377\u723e\u8499\u751f\u6210\u4e2d\u767c\u63ee\u4f5c\u7528\uff0c\u4e5f\u662f\u9ad4\u5167\u4e3b\u8981\u7684\u89e3\u6bd2\u5668\u5b98\u3002<\/p>\n<p>\u809d\u81df\u89e3\u6bd2\u5206\u70ba\u5169\u985e\u3002\u5b83\u5011\u5206\u5225\u88ab\u7a31\u70ba\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u548c\u7b2c\u4e8c\u968e\u6bb5\u8def\u5f91\u3002<\/p>\n<h2><strong>\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u8def\u5f91<\/strong><\/h2>\n<p>\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u662f\u5c0d\u6297\u6bd2\u7d20\u7684\u7b2c\u4e00\u9053\u9632\u7dda\uff0c\u7531\u4e00\u7d44\u7a31\u70ba\u7d30\u80de\u8272\u7d20P450\u5bb6\u65cf\u7684\u9176\u7d44\u6210\u3002\u9019\u4e9b\u9176\u80fd\u4e2d\u548c\u9152\u7cbe\u548c\u5496\u5561\u56e0\u7b49\u7269\u8cea\uff0c\u5b83\u5011\u6703\u5c07\u9019\u4e9b\u6bd2\u7d20\u8f49\u5316\u6210\u8f03\u4f4e\u6bd2\u6027\u7684\u7269\u8cea\uff0c\u4ee5\u63d0\u4f9b\u4fdd\u8b77\u3002<\/p>\n<p>\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u7684\u526f\u7522\u54c1\u4ecd\u5c0d\u8eab\u9ad4\u69cb\u6210\u6bd2\u6027\u5a01\u8105\u3002\u5982\u679c\u7e7c\u7e8c\u8b93\u6bd2\u7d20\u805a\u7a4d\u7559\u5728\u809d\u81df\u4e2d\uff0c\u5b83\u5011\u6703\u640d\u50b7DNA\u548c\u86cb\u767d\u8cea\u3002\u9019\u5c31\u662f\u809d\u81df\u89e3\u6bd2\u7b2c\u4e8c\u968e\u6bb5\u7684\u4f5c\u7528\uff0c\u78ba\u4fdd\u6bd2\u7d20\u4e0d\u6703\u7d2f\u7a4d\uff0c\u4e26\u5c0d\u6bd2\u7d20\u9032\u884c\u6700\u7d42\u7684\u4e2d\u548c\uff0c\u8b93\u6bd2\u7d20\u53ef\u4ee5\u5f9e\u8eab\u9ad4\u4e2d\u6392\u9664\u3002<\/p>\n<h2><strong>\u809d\u81df\u89e3\u6bd2\u7b2c\u4e8c\u968e\u6bb5\u8def\u5f91<\/strong><\/h2>\n<p>\u809d\u81df\u89e3\u6bd2\u7b2c\u4e8c\u968e\u6bb5\u6703\u4e2d\u548c\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u7684\u526f\u7522\u54c1\uff0c\u4ee5\u53ca\u5176\u4ed6\u7684\u6b98\u7559\u6bd2\u7d20\u3002\u9019\u500b\u904e\u7a0b\u6703\u5c07\u6bd2\u7d20\u8f49\u8b8a\u70ba\u6c34\u6eb6\u6027\uff0c\u9019\u6a23\u5c31\u80fd\u5f9e\u8eab\u9ad4\u6392\u51fa\u9ad4\u5916\u3002\u9019\u500b\u904e\u7a0b\u88ab\u7a31\u70ba\u63a5\u5408\u4f5c\u7528\u3002\u9ea9\u80f1\u7518\u80bd\u3001\u786b\u9178\u9e7d\u3001\u548c\u7518\u80fa\u9178\u662f\u8ca0\u8cac\u9019\u500b\u904e\u7a0b\u7684\u4e3b\u8981\u5206\u5b50\u3002<\/p>\n<p>\u5728\u6b63\u5e38\u689d\u4ef6\u4e0b\uff0c\u809d\u81df\u89e3\u6bd2\u7b2c\u4e8c\u968e\u6bb5\u9176\u6703\u7522\u751f\u4f4e\u6fc3\u5ea6\u7684\u9ea9\u80f1\u7518\u80bd\u3002\u5982\u679c\u5728\u9ad8\u6bd2\u6027\u58d3\u529b\u7684\u6642\u671f\uff0c\u8eab\u9ad4\u6703\u589e\u52a0\u9ea9\u80f1\u7518\u80bd\u7684\u7522\u751f\u3002<\/p>\n<h3><strong>\u9ea9\u80f1\u7518\u80bd<\/strong><\/h3>\n<p><a href=\"https:\/\/askthescientists.com\/zh-hant\/qa\/liver-detoxification-pathways\/\">\u9ea9\u80f1\u7518\u80bd<\/a>\u5c0d\u4eba\u985e\u4f86\u8aaa\u975e\u5e38\u91cd\u8981\uff0c\u751a\u81f3\u7a31\u70ba\u300c\u4e3b\u6297\u6c27\u5316\u5291\u300d\uff0c\u56e0\u70ba\u5b83\u662f\u8eab\u9ad4\u6700\u8c50\u5bcc\u7684\u6297\u6c27\u5316\u5291\uff0c\u53ef\u4ee5\u5728\u809d\u81df\u4e2d\u518d\u751f\u3002<\/p>\n<p>\u9ea9\u80f1\u7518\u80bd\u5bcc\u542b\u65bc\u8606\u7b4d\u3001\u916a\u68a8\u3001\u83e0\u83dc\u3001\u7da0\u82b1\u6930\u548c\u4e00\u4e9b\u71df\u990a\u88dc\u5145\u54c1\u4e2d\u3002\u4ee4\u4eba\u907a\u61be\u7684\u662f\uff0c\u9ea9\u80f1\u7518\u80bd\u5f88\u96e3\u5f9e\u98df\u7269\u4e2d\u651d\u53d6\uff0c\u5b83\u6703\u5728\u88ab\u8eab\u9ad4\u5438\u6536\u4e4b\u524d\u5148\u88ab\u6d88\u5316\u9176\u5206\u89e3\uff1b\u9ea9\u80f1\u7518\u80bd\u4e5f\u6c92\u6709\u76f4\u63a5\u7684\u904b\u9001\u7cfb\u7d71\u3002<\/p>\n<p>\u96d6\u7136\u9ea9\u80f1\u7518\u80bd\u4e0d\u6613\u5f9e\u98f2\u98df\u4e2d\u651d\u53d6\uff0c\u4f46\u98f2\u98df\u78ba\u5be6\u6703\u5f71\u97ff\u9ad4\u5167\u7684\u6fc3\u5ea6\u3002\u8eab\u9ad4\u9700\u8981\u88fd\u9020\u9ea9\u80f1\u7518\u80bd\u7684\u95dc\u9375\u6210\u4efd\uff0c\u76ee\u524d\u5df2\u77e5\u67d0\u4e9b\u98df\u7269\u548c\u71df\u990a\u7d20\u53ef\u4ee5\u505a\u70ba\u63d0\u4f9b\u7684\u4f86\u6e90\u3002\u5403\u9032\u9019\u4e9b\u6210\u4efd\u53ef\u4ee5\u589e\u52a0\u8eab\u9ad4\u9ea9\u80f1\u7518\u80bd\u7684\u7522\u91cf\u3002\u9019\u4e9b\u5305\u62ec\u7852\u3001\u7dad\u751f\u7d20 E\u3001\u5341\u5b57\u82b1\u79d1\u852c\u83dc\u3001\u03b1-\u786b\u8f9b\u9178\u3001\u5976\u858a\u8349\u548c\u80f1\u6c28\u9178\u3002<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-large wp-image-8719\" src=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1030x636.jpeg\" alt=\"glutathione foods\" width=\"1030\" height=\"636\" srcset=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1030x636.jpeg 1030w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-300x185.jpeg 300w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-768x474.jpeg 768w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1500x926.jpeg 1500w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-705x435.jpeg 705w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-450x278.jpeg 450w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables.jpeg 1200w\" sizes=\"(max-width: 1030px) 100vw, 1030px\" \/><\/p>\n<h3><strong>\u7dad\u751f\u7d20C<\/strong><\/h3>\n<p><a href=\"\/?p=2381\">\u7dad\u751f\u7d20C<\/a>\u5728\u809d\u81df\u89e3\u6bd2\u8def\u5f91\u4e2d\u4e5f\u5f88\u91cd\u8981\uff0c\u5b83\u6709\u52a9\u65bc\u4fdd\u8b77\u5728\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u548c\u7b2c\u4e8c\u968e\u6bb5\u8def\u5f91\u4e2d\u6240\u7522\u751f\u7684\u809d\u81df\u89e3\u6bd2\u9176\u514d\u53d7\u6c27\u5316\u640d\u50b7\u3002\u7dad\u751f\u7d20C\u6709\u52a9\u65bc\u4fdd\u8b77\u809d\u7d44\u7e54\u514d\u53d7\u6c27\u5316\u640d\u50b7\uff1b\u67d0\u4e9b\u7814\u7a76\u9084\u767c\u73fe\u7dad\u751f\u7d20C\u53ef\u80fd\u5728\u53bb\u9664\u6bd2\u7d20\u7684\u904e\u7a0b\u4e2d\u767c\u63ee\u4f5c\u7528\u3002<\/p>\n<p>\u7dad\u751f\u7d20C\u5728\u9ad4\u5167\u6703\u53d7\u5230\u56b4\u5bc6\u7684\u63a7\u5236\uff0c\u8840\u6db2\u6fc3\u5ea6\u4e3b\u8981\u7531\u7dad\u751f\u7d20C\u7684\u651d\u53d6\u91cf\u548c\u814e\u81df\u7684\u8abf\u7bc0\u4f86\u6c7a\u5b9a\u3002\u7814\u7a76\u986f\u793a\uff0c\u4e00\u4e9b\u690d\u7269\u5316\u5b78\u7269\u8cea\u53ef\u80fd\u6703\u589e\u52a0\u8840\u6f3f\u5167\u7684\u7dad\u751f\u7d20C\uff0c\u5373\u4fbf\u662f\u5728\u672a\u651d\u53d6\u7dad\u751f\u7d20C\u7684\u72c0\u6cc1\u4e0b\u3002<\/p>\n<p>\u7dad\u751f\u7d20C\u542b\u91cf\u6700\u8c50\u5bcc\u7684\u98df\u7269\uff1a<\/p>\n<ul>\n<li>\u54c8\u5bc6\u74dc<\/li>\n<li>\u8461\u8404\u67da<\/li>\n<li>\u871c\u9999\u74dc<\/li>\n<li>\u5947\u7570\u679c<\/li>\n<li>\u8292\u679c<\/li>\n<li>\u6a59\u5b50\u548c\u5176\u4ed6\u67d1\u6a58\u985e\u6c34\u679c<\/li>\n<li>\u8349\u8393<\/li>\n<li>\u897f\u74dc<\/li>\n<\/ul>\n<h1><strong>\u589e\u52a0\u9ea9\u80f1\u7518\u80bd\u751f\u7522\u7684\u81e8\u5e8a\u7814\u7a76<\/strong><\/h1>\n<p>\u79d1\u5b78\u5bb6\u5011\u5c0d\u6df7\u5408\u71df\u990a\u7d20\u9032\u884c\u4e86\u4e00\u9805\u96d9\u76f2\u5b89\u6170\u5291\u5c0d\u7167\u7814\u7a76\u5be6\u9a57\uff0c\u76ee\u7684\u662f\u78ba\u5b9a\u5b83\u5011\u662f\u5426\u4fc3\u9032\u589e\u52a0\u8840\u6f3f\u7a40\u80f1\u7518\u80bd\u548c\u7dad\u751f\u7d20 C\u3002\u7814\u7a76\u5e72\u9810\u7d44\u4f7f\u7528\u4e86 USANA Health Sciences \u63d0\u4f9b\u7684\u88dc\u5145\u54c1\u3002\u88dc\u5145\u54c1\u542b\u6709\u751f\u7269\u7d20\u3001\u81bd\u9e7c\u3001\u5976\u858a\u8349\u63d0\u53d6\u7269\u3001N-\u4e59\u9170 L-\u80f1\u6c28\u9178\u3001\u03b1-\u786b\u8f9b\u9178\u3001\u897f\u862d\u82b1\u6fc3\u7e2e\u7269\u3001\u7da0\u8336\u63d0\u53d6\u7269\u3001\u6a44\u6b16\u679c\u63d0\u53d6\u7269\u548c\u8591\u9ec3\u63d0\u53d6\u7269\u300215 \u540d\u5065\u5eb7\u5fd7\u9858\u8005\u53c3\u8207\u4e86\u9019\u9805\u7814\u7a76\u3002\u53d7\u8a66\u8005\u63a5\u53d7\u4e86 28 \u5929\u7684\u7814\u7a76\u6cbb\u7642\u6216\u5b89\u6170\u5291\u4e26\u5728\u7b2c 1\u300114 \u548c 28 \u5929\uff0c\u62bd\u53d6\u8840\u6a23\u6e2c\u91cf\u8840\u6f3f\u7dad\u751f\u7d20 C \u548c\u7a40\u80f1\u7518\u80bd\u3002<\/p>\n<h2><strong>\u5be6\u9a57\u7d50\u679c<\/strong><\/h2>\n<ul>\n<li>\u7b2c\u4e00\u6b21\u7642\u7a0b\u5f8c\u5169\u5c0f\u6642\uff0c\u7642\u7a0b\u589e\u52a0\u8840\u6f3f\u7a40\u80f1\u7518\u80bd\uff0c\u7642\u7a0b\u5f8c\u516b\u5c0f\u6642\u8840\u6f3f\u7a40\u80f1\u7518\u80bd\u660e\u986f\u589e\u52a0\u3002<\/li>\n<li>\u5be6\u9a57\u7d50\u675f\u6642\uff0c\u8840\u6f3f\u7a40\u80f1\u7518\u80bd\u6c34\u5e73\u63d0\u5347\u4e86 74%\u3002<\/li>\n<li>\u7b2c\u4e00\u6b21\u6cbb\u7642\u5f8c\u7684\u5169\u5c0f\u6642\u5167\uff0c\u8840\u6f3f\u7dad\u751f\u7d20 C \u660e\u986f\u8457\u4e0a\u5347\u3002\u9019\u5728\u6574\u500b\u6025\u6027\u671f\uff080-8 \u5c0f\u6642\u6642\u9593\u9ede\uff09\u4e2d\u4fdd\u6301\u4e0d\u8b8a\u3002<\/li>\n<\/ul>\n<p>\u7d50\u679c\u986f\u793a\u9019\u4e9b\u71df\u990a\u7d20\u7684\u5354\u540c\u4f5c\u7528\u3002\u7642\u7a0b\u914d\u65b9\u63d0\u9ad8\u4e86\u7a40\u80f1\u7518\u80bd\u548c\u7dad\u751f\u7d20 C \u7684\u6c34\u5e73\u3002\u5b83\u4e0a\u8abf\u4e86\u8eab\u9ad4\u5728\u6392\u6bd2\u53cd\u61c9\u4e2d\u5229\u7528\u7a40\u80f1\u7518\u80bd\u7684\u80fd\u529b\uff0c\u9084\u589e\u52a0\u4e86\u8eab\u9ad4\u7684\u6297\u6c27\u5316\u80fd\u529b\u3002\u5f8c\u7e8c\u5831\u544a\u6307\u51fa\uff0c\u7a40\u80f1\u7518\u80bd\u548c\u7dad\u751f\u7d20 C \u7684\u589e\u52a0\u5177\u6709\u81e8\u5e8a\u76ca\u8655\u3002\u670d\u7528\u88dc\u5145\u54c1\u7684\u53d7\u8a66\u8005\u6bd4\u670d\u7528\u5b89\u6170\u5291\u7684\u53d7\u8a66\u8005\u66f4\u80fd\u62b5\u6297\u6c27\u5316\u640d\u50b7\u3002<\/p>\n<h2><strong>\u7814\u7a76\u7d50\u8ad6<\/strong><\/h2>\n<p>\u9019\u9805\u7d50\u679c\u4e5f\u547c\u61c9\u4e86\u5148\u524d\u7684\u7814\u7a76\uff0c\u8b49\u660e\u5373\u4fbf\u662f\u5728\u672a\u651d\u53d6\u7dad\u751f\u7d20C\u7684\u72c0\u6cc1\u4e0b\uff0c\u67d0\u4e9b\u690d\u7269\u5316\u5b78\u7269\u8cea\u53ef\u80fd\u6703\u589e\u52a0\u8840\u6f3f\u5167\u7684\u7dad\u751f\u7d20C\uff0c\u4e26\u4e14\u9019\u4e9b\u690d\u7269\u5316\u5b78\u7269\u8cea\u4e5f\u80fd\u63d0\u4f9b\u4e00\u7a2e\u8a31\u591a\u6210\u4efd\u7684\u7279\u5b9a\u6df7\u5408\u7269\uff0c\u4f86\u589e\u52a0\u8eab\u9ad4\u9ea9\u80f1\u7518\u80bd\u7684\u751f\u7522\u3002<\/p>\n<div  class='togglecontainer av-4rizae-a600969afc24f6dbeb203a9fdf1b11b7  avia-builder-el-0  avia-builder-el-no-sibling  toggle_close_all' >\n<section class='av_toggle_section av-35153q-bc1a09484f3ac00b50ef4757410d204e'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><p id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"\u53c3\u8003\u8cc7\u6599\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: \u53c3\u8003\u8cc7\u6599\" data-aria_expanded=\"Click to collapse: \u53c3\u8003\u8cc7\u6599\">\u53c3\u8003\u8cc7\u6599<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color '  itemprop=\"text\" ><p><a href=\"https:\/\/mickschroeder.com\/citation\/?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F9468229\">Flora K, Hahn M, Rosen H, Benner K. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol. 1998;93(2):139-43.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21801862\/\">Guo J, Prokai-tatrai K, Nguyen V, Rauniyar N, Ughy B, Prokai L. Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria. J Proteomics. 2011;74(11):2370-9.<\/a><\/p>\n<p><a href=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/03\/CR_HepasilDTX_Poster.pdf\">Hepasil DTX\u2122 Increases Antioxidant and Detoxification Capacity by Boosting Glutathione and Vitamin C (1)<\/a><\/p>\n<p><a href=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/03\/CR_HepasilDTX_Poster_2.pdf\">Hepasil DTX\u2122 Increases Antioxidant and Detoxification Capacity by Boosting Glutathione and Vitamin C (2)<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19875138\">Kesinger NG, Stevens JF. Covalent interaction of ascorbic acid with natural products. Phytochemistry. 2009;70(17-18):1930-9.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19819328\">Kuiper HC, Langsdorf BL, Miranda CL, et al. Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study. Free Radic Biol Med. 2010;48(1):65-72.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18442969\">Kuiper HC, Miranda CL, Sowell JD, Stevens JF. Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress. J Biol Chem. 2008;283(25):17131-8.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10586080\">Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB. Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis. J Immunol. 1999;163(12):6800-9.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16296871\">Medina J, Moreno-otero R. Pathophysiological basis for antioxidant therapy in chronic liver disease. Drugs. 2005;65(17):2445-61.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/4436301\">Pabst MJ, Habig WH, Jakoby WB. Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J Biol Chem. 1974;249(22):7140-7.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16603143\">Rabovsky A, Cuomo J, Eich N. Measurement of plasma antioxidant reserve after supplementation with various antioxidants in healthy subjects. Clin Chim Acta. 2006;371(1-2):55-60.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11735632\">Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61(14):2035-63.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18203133\">Stevens JF, Maier CS. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol Nutr Food Res. 2008;52(1):7-25.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20519558\">Timpson NJ, Forouhi NG, Brion MJ, et al. Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with &gt;15,000 participants. Am J Clin Nutr. 2010;92(2):375-82.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11520257\">Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs. 2001;15(7):465-89.<\/a><\/p>\n<\/div><\/div><\/div><\/section>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u809d\u81df\u662f\u91cd\u8981\u5668\u5b98\uff0c\u5b83\u6703\u5728\u4ee3\u8b1d\u3001\u6d88\u5316\u3001\u80fd\u91cf\u5132\u5b58\u3001\u548c\u8377\u723e\u8499\u751f\u6210\u4e2d\u767c\u63ee\u4f5c\u7528\uff0c\u4e5f\u662f\u9ad4\u5167\u4e3b\u8981\u7684\u89e3\u6bd2\u5668\u5b98\u3002 \u809d\u81df\u89e3\u6bd2\u5206\u70ba\u5169\u985e\u3002\u5b83\u5011\u5206\u5225\u88ab\u7a31\u70ba\u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u548c\u7b2c\u4e8c\u968e\u6bb5\u8def\u5f91\u3002 \u809d\u81df\u89e3\u6bd2\u7b2c\u4e00\u968e\u6bb5\u8def\u5f91 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