{"id":72346,"date":"2017-06-26T08:30:12","date_gmt":"2017-06-26T14:30:12","guid":{"rendered":"https:\/\/askthescientists.com\/qa\/liver-detoxification-pathways\/"},"modified":"2023-06-27T09:06:52","modified_gmt":"2023-06-27T15:06:52","slug":"liver-detoxification-pathways","status":"publish","type":"qa","link":"https:\/\/askthescientists.com\/zh-hans\/qa\/liver-detoxification-pathways\/","title":{"rendered":"\u809d\u810f\u89e3\u6bd2\u8def\u5f84"},"content":{"rendered":"<p><img decoding=\"async\" class=\"aligncenter size-large wp-image-8718\" src=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-835x486.jpeg\" alt=\"liver detoxification\" width=\"835\" height=\"486\" srcset=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-835x486.jpeg 835w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-400x233.jpeg 400w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-768x447.jpeg 768w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-705x411.jpeg 705w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159-450x262.jpeg 450w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/liver-e1533581304159.jpeg 1200w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><\/p>\n\n<p>\u809d\u810f\u662f\u91cd\u8981\u5668\u5b98\uff0c\u5b83\u5728\u4ee3\u8c22\u3001\u6d88\u5316\u3001\u80fd\u91cf\u50a8\u5b58\u3001\u548c\u8377\u5c14\u8499\u751f\u6210\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u4e5f\u662f\u4f53\u5185\u4e3b\u8981\u7684\u89e3\u6bd2\u5668\u5b98\u3002<\/p>\n<p>\u809d\u810f\u89e3\u6bd2\u5206\u4e3a\u4e24\u7c7b\u3002\u5b83\u4eec\u5206\u522b\u88ab\u79f0\u4e3a\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u548c\u7b2c\u4e8c\u9636\u6bb5\u8def\u5f84\u3002<\/p>\n<h2><strong>\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u8def\u5f84<\/strong><\/h2>\n<p>\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u662f\u5bf9\u6297\u6bd2\u7d20\u7684\u7b2c\u4e00\u9053\u9632\u7ebf\uff0c\u7531\u4e00\u7ec4\u79f0\u4e3a\u7ec6\u80de\u8272\u7d20 P450 \u5bb6\u65cf\u7684\u9176\u7ec4\u6210\u3002\u8fd9\u4e9b\u9176\u80fd\u4e2d\u548c\u9152\u7cbe\u548c\u5496\u5561\u56e0\u7b49\u7269\u8d28\uff0c\u5b83\u4eec\u4f1a\u5c06\u8fd9\u4e9b\u6bd2\u7d20\u8f6c\u5316\u6210\u8f83\u4f4e\u6bd2\u6027\u7684\u7269\u8d28\uff0c\u4ee5\u63d0\u4f9b\u4fdd\u62a4\u3002<\/p>\n<p>\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u7684\u526f\u4ea7\u54c1\u4ecd\u5bf9\u8eab\u4f53\u6784\u6210\u6bd2\u6027\u5a01\u80c1\u3002\u5982\u679c\u7ee7\u7eed\u8ba9\u6bd2\u7d20\u805a\u79ef\u7559\u5728\u809d\u810f\u4e2d\uff0c\u5b83\u4eec\u4f1a\u635f\u4f24 DNA \u548c\u86cb\u767d\u8d28\u3002\u8fd9\u5c31\u662f\u809d\u810f\u89e3\u6bd2\u7b2c\u4e8c\u9636\u6bb5\u7684\u4f5c\u7528\uff0c\u786e\u4fdd\u6bd2\u7d20\u4e0d\u4f1a\u7d2f\u79ef\uff0c\u5e76\u5bf9\u6bd2\u7d20\u8fdb\u884c\u6700\u7ec8\u7684\u4e2d\u548c\uff0c\u8ba9\u6bd2\u7d20\u53ef\u4ee5\u4ece\u8eab\u4f53\u4e2d\u6392\u9664\u3002<\/p>\n<h2><strong>\u809d\u810f\u89e3\u6bd2\u7b2c\u4e8c\u9636\u6bb5\u8def\u5f84<\/strong><\/h2>\n<p>\u809d\u810f\u89e3\u6bd2\u7b2c\u4e8c\u9636\u6bb5\u4f1a\u4e2d\u548c\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u7684\u526f\u4ea7\u54c1\uff0c\u4ee5\u53ca\u5176\u5b83\u7684\u6b8b\u7559\u6bd2\u7d20\u3002\u8fd9\u4e2a\u8fc7\u7a0b\u4f1a\u5c06\u6bd2\u7d20\u8f6c\u53d8\u4e3a\u6c34\u6eb6\u6027\uff0c\u8fd9\u6837\u5c31\u80fd\u4ece\u8eab\u4f53\u6392\u51fa\u4f53\u5916\u3002\u8fd9\u4e2a\u8fc7\u7a0b\u88ab\u79f0\u4e3a\u63a5\u5408\u4f5c\u7528\u3002\u9eb8\u80f1\u7518\u80bd\u3001\u786b\u9178\u76d0\u548c\u7518\u80fa\u9178\u662f\u8d1f\u8d23\u8fd9\u4e2a\u8fc7\u7a0b\u7684\u4e3b\u8981\u5206\u5b50\u3002<\/p>\n<p>\u5728\u6b63\u5e38\u6761\u4ef6\u4e0b\uff0c\u809d\u810f\u89e3\u6bd2\u7b2c\u4e8c\u9636\u6bb5\u9176\u4f1a\u4ea7\u751f\u4f4e\u6d53\u5ea6\u7684\u9eb8\u80f1\u7518\u80bd\u3002\u5982\u679c\u5728\u9ad8\u6bd2\u6027\u538b\u529b\u7684\u65f6\u671f\uff0c\u8eab\u4f53\u4f1a\u589e\u52a0\u9eb8\u80f1\u7518\u80bd\u7684\u4ea7\u751f\u3002<\/p>\n<h3><strong>\u9eb8\u80f1\u7518\u80bd<\/strong><\/h3>\n<p>\u9eb8\u80f1\u7518\u80bd\u5bf9\u4eba\u7c7b\u6765\u8bf4\u975e\u5e38\u91cd\u8981\uff0c\u751a\u81f3\u79f0\u4e3a\u201c\u4e3b\u6297\u6c27\u5316\u5242\u201d\uff0c\u56e0\u4e3a\u5b83\u662f\u8eab\u4f53\u6700\u4e30\u5bcc\u7684\u6297\u6c27\u5316\u5242\uff0c\u53ef\u4ee5\u5728\u809d\u810f\u4e2d\u518d\u751f\u3002<\/p>\n<p>\u9eb8\u80f1\u7518\u80bd\u5bcc\u542b\u4e8e\u82a6\u7b0b\u3001\u916a\u68a8\u3001\u83e0\u83dc\u3001\u7eff\u82b1\u6930\u548c\u4e00\u4e9b\u8425\u517b\u8865\u5145\u54c1\u4e2d\u3002\u4ee4\u4eba\u9057\u61be\u7684\u662f\uff0c\u9eb8\u80f1\u7518\u80bd\u5f88\u96be\u4ece\u98df\u7269\u4e2d\u6444\u53d6\uff0c\u5b83\u4f1a\u5728\u88ab\u8eab\u4f53\u5438\u6536\u4e4b\u524d\u5148\u88ab\u6d88\u5316\u9176\u5206\u89e3\uff1b\u9eb8\u80f1\u7518\u80bd\u4e5f\u6ca1\u6709\u76f4\u63a5\u7684\u8fd0\u9001\u7cfb\u7edf\u3002<\/p>\n<p>\u867d\u7136\u9eb8\u80f1\u7518\u80bd\u4e0d\u6613\u4ece\u996e\u98df\u4e2d\u6444\u53d6\uff0c\u4f46\u996e\u98df\u786e\u5b9e\u4f1a\u5f71\u54cd\u4f53\u5185\u7684\u6d53\u5ea6\u3002\u8eab\u4f53\u9700\u8981\u5236\u9020\u9eb8\u80f1\u7518\u80bd\u7684\u5173\u952e\u6210\u5206\uff0c\u76ee\u524d\u5df2\u77e5\u67d0\u4e9b\u98df\u7269\u548c\u8425\u517b\u7d20\u53ef\u4ee5\u505a\u4e3a\u63d0\u4f9b\u7684\u6765\u6e90\u3002\u5403\u8fdb\u8fd9\u4e9b\u6210\u5206\u53ef\u4ee5\u589e\u52a0\u8eab\u4f53\u9eb8\u80f1\u7518\u80bd\u7684\u4ea7\u91cf\uff0c\u5305\u62ec\u7852\u3001\u7ef4\u751f\u7d20 E\u3001\u5341\u5b57\u82b1\u79d1\u852c\u83dc\u3001\u03b1-\u786b\u8f9b\u9178\u3001\u82e6\u84df\u8349\u3001\u4ee5\u53ca N-\u4e59\u9170\u534a\u80f1\u80fa\u9178\u3002<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-large wp-image-8719\" src=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1030x636.jpeg\" alt=\"glutathione foods\" width=\"1030\" height=\"636\" srcset=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1030x636.jpeg 1030w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-300x185.jpeg 300w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-768x474.jpeg 768w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-1500x926.jpeg 1500w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-705x435.jpeg 705w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables-450x278.jpeg 450w, https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/06\/cruciferous-vegetables.jpeg 1200w\" sizes=\"(max-width: 1030px) 100vw, 1030px\" \/><\/p>\n<h3><strong>\u7ef4\u751f\u7d20<\/strong> <strong>C<\/strong><\/h3>\n<p>\u7ef4\u751f\u7d20 C \u5728\u809d\u810f\u89e3\u6bd2\u8def\u5f84\u4e2d\u4e5f\u5f88\u91cd\u8981\uff0c\u5b83\u6709\u52a9\u4e8e\u4fdd\u62a4\u5728\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u548c\u7b2c\u4e8c\u9636\u6bb5\u8def\u5f84\u4e2d\u6240\u4ea7\u751f\u7684\u809d\u810f\u89e3\u6bd2\u9176\u514d\u53d7\u6c27\u5316\u635f\u4f24\u3002\u7ef4\u751f\u7d20 C \u6709\u52a9\u4e8e\u4fdd\u62a4\u809d\u7ec4\u7ec7\u514d\u53d7\u6c27\u5316\u635f\u4f24\uff1b\u67d0\u4e9b\u7814\u7a76\u8fd8\u53d1\u73b0\u7ef4\u751f\u7d20 C \u53ef\u80fd\u5728\u53bb\u9664\u6bd2\u7d20\u7684\u8fc7\u7a0b\u4e2d\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n<p>\u7ef4\u751f\u7d20 C \u5728\u4f53\u5185\u4f1a\u53d7\u5230\u4e25\u5bc6\u7684\u63a7\u5236\uff0c\u8840\u6db2\u6d53\u5ea6\u4e3b\u8981\u7531\u7ef4\u751f\u7d20 C \u7684\u6444\u53d6\u91cf\u548c\u80be\u810f\u7684\u8c03\u8282\u6765\u51b3\u5b9a\u3002\u7814\u7a76\u663e\u793a\uff0c\u4e00\u4e9b\u690d\u7269\u5316\u5b66\u7269\u8d28\u53ef\u80fd\u4f1a\u589e\u52a0\u8840\u6d46\u5185\u7684\u7ef4\u751f\u7d20 C\uff0c\u5373\u4fbf\u662f\u5728\u672a\u6444\u53d6\u7ef4\u751f\u7d20C\u7684\u72b6\u51b5\u4e0b\u3002<\/p>\n<p>\u7ef4\u751f\u7d20 C 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\u540e\u4e24\u5c0f\u65f6\uff0c\u8840\u6d46\u5185\u9eb8\u80f1\u7518\u80bd\u542b\u91cf\u589e\u52a0\uff0c\u670d\u7528\u540e\u516b\u5c0f\u65f6\uff0c\u8840\u6d46\u9eb8\u80f1\u7518\u80bd\u660e\u663e\u589e\u52a0\u3002<\/li>\n<li>\u7814\u7a76\u7ed3\u675f\u65f6\uff0c\u8840\u6d46\u5185\u7684\u9eb8\u80f1\u7518\u80bd\u6d53\u5ea6\u589e\u52a0\u4e86 74%\u3002<\/li>\n<li>\u5728\u7b2c\u4e00\u6b21\u670d\u7528\u809d\u810f\u5b9d DTX\u2122 \u540e\u4e24\u5c0f\u65f6\u663e\u8457\u63d0\u5347\u8840\u6d46\u4e2d\u7684\u7ef4\u751f\u7d20 C \u6d53\u5ea6\uff0c\u5e76\u4e14\u5728\u6574\u4e2a\u9ad8\u5cf0\u671f\uff080\uff0d8 \u5c0f\u65f6\u7684\u65f6\u95f4\u70b9\uff09\u4e2d\u7ef4\u6301\u9ad8\u6d53\u5ea6\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u9879\u7ed3\u679c\u663e\u793a\u51fa\u8fd9\u4e9b\u8425\u517b\u7d20\u7684\u534f\u540c\u6548\u5e94\uff0c\u670d\u7528\u4e4b\u540e\u63d0\u9ad8\u4e86\u9eb8\u80f1\u7518\u80bd\u548c\u7ef4\u751f\u7d20 C \u6d53\u5ea6\uff0c\u5e76\u4e14\u4e0a\u8c03\u4e86\u8eab\u4f53\u5728\u89e3\u6bd2\u53cd\u5e94\u4e2d\u5229\u7528\u9eb8\u80f1\u7518\u80bd\u7684\u80fd\u529b\u3002\u5b83\u4e5f\u589e\u52a0\u4e86\u8eab\u4f53\u7684\u6297\u6c27\u5316\u80fd\u529b\u3002<\/p>\n<p>\u540e\u7eed\u62a5\u544a\u663e\u793a\uff0c\u9eb8\u80f1\u7518\u80bd\u548c\u7ef4\u751f\u7d20 C \u7684\u589e\u52a0\u5177\u6709\u4e34\u5e8a\u6548\u76ca\u3002\u670d\u7528\u809d\u810f\u5b9d DTX\u2122 \u7684\u53d7\u8bd5\u8005\u6bd4\u670d\u7528\u5b89\u6170\u5242\u7684\u53d7\u8bd5\u8005\u663e\u8457\u66f4\u6709\u80fd\u529b\u5bf9\u6297\u6c27\u5316\u635f\u4f24\u3002<\/p>\n<h2><strong>\u7814\u7a76\u7ed3\u8bba<\/strong><\/h2>\n<p>\u8fd9\u9879\u7ed3\u679c\u4e5f\u547c\u5e94\u4e86\u5148\u524d\u7684\u7814\u7a76\uff0c\u8bc1\u660e\u5373\u4fbf\u662f\u5728\u672a\u6444\u53d6\u7ef4\u751f\u7d20 C \u7684\u72b6\u51b5\u4e0b\uff0c\u67d0\u4e9b\u690d\u7269\u5316\u5b66\u7269\u8d28\u53ef\u80fd\u4f1a\u589e\u52a0\u8840\u6d46\u5185\u7684\u7ef4\u751f\u7d20 C\uff0c\u5e76\u4e14\u8fd9\u4e9b\u690d\u7269\u5316\u5b66\u7269\u8d28\u4e5f\u80fd\u63d0\u4f9b\u4e00\u79cd\u8bb8\u591a\u6210\u5206\u7684\u7279\u5b9a\u6df7\u5408\u7269\uff0c\u6765\u589e\u52a0\u8eab\u4f53\u9eb8\u80f1\u7518\u80bd\u7684\u751f\u4ea7\u3002<\/p>\n<div  class='togglecontainer av-4ofi1o-07d45f22b5bc311d3835afea37633294  avia-builder-el-0  avia-builder-el-no-sibling  toggle_close_all' >\n<section class='av_toggle_section av-1vsdy4-deb5a5a0d1770e83731a7ff703175aff'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} \"  ><p id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"\u53c2\u8003\u8d44\u6599\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: \u53c2\u8003\u8d44\u6599\" data-aria_expanded=\"Click to collapse: \u53c2\u8003\u8d44\u6599\">\u53c2\u8003\u8d44\u6599<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color '  itemprop=\"text\" ><p><a href=\"https:\/\/mickschroeder.com\/citation\/?q=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F9468229\">Flora K, Hahn M, Rosen H, Benner K. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol. 1998;93(2):139-43.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21801862\/\">Guo J, Prokai-tatrai K, Nguyen V, Rauniyar N, Ughy B, Prokai L. Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria. J Proteomics. 2011;74(11):2370-9.<\/a><\/p>\n<p><a href=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/03\/CR_HepasilDTX_Poster.pdf\">Hepasil DTX\u2122 Increases Antioxidant and Detoxification Capacity by Boosting Glutathione and Vitamin C (1)<\/a><\/p>\n<p><a href=\"https:\/\/askthescientists.com\/wp-content\/uploads\/2017\/03\/CR_HepasilDTX_Poster_2.pdf\">Hepasil DTX\u2122 Increases Antioxidant and Detoxification Capacity by Boosting Glutathione and Vitamin C (2)<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19875138\">Kesinger NG, Stevens JF. Covalent interaction of ascorbic acid with natural products. Phytochemistry. 2009;70(17-18):1930-9.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19819328\">Kuiper HC, Langsdorf BL, Miranda CL, et al. Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study. Free Radic Biol Med. 2010;48(1):65-72.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18442969\">Kuiper HC, Miranda CL, Sowell JD, Stevens JF. Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress. J Biol Chem. 2008;283(25):17131-8.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10586080\">Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB. Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis. J Immunol. 1999;163(12):6800-9.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16296871\">Medina J, Moreno-otero R. Pathophysiological basis for antioxidant therapy in chronic liver disease. Drugs. 2005;65(17):2445-61.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/4436301\">Pabst MJ, Habig WH, Jakoby WB. Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J Biol Chem. 1974;249(22):7140-7.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16603143\">Rabovsky A, Cuomo J, Eich N. Measurement of plasma antioxidant reserve after supplementation with various antioxidants in healthy subjects. Clin Chim Acta. 2006;371(1-2):55-60.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11735632\">Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61(14):2035-63.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18203133\">Stevens JF, Maier CS. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol Nutr Food Res. 2008;52(1):7-25.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20519558\">Timpson NJ, Forouhi NG, Brion MJ, et al. Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with &gt;15,000 participants. Am J Clin Nutr. 2010;92(2):375-82.<\/a><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11520257\">Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic disorders. BioDrugs. 2001;15(7):465-89.<\/a><\/p>\n<\/div><\/div><\/div><\/section>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u809d\u810f\u662f\u91cd\u8981\u5668\u5b98\uff0c\u5b83\u5728\u4ee3\u8c22\u3001\u6d88\u5316\u3001\u80fd\u91cf\u50a8\u5b58\u3001\u548c\u8377\u5c14\u8499\u751f\u6210\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u4e5f\u662f\u4f53\u5185\u4e3b\u8981\u7684\u89e3\u6bd2\u5668\u5b98\u3002 \u809d\u810f\u89e3\u6bd2\u5206\u4e3a\u4e24\u7c7b\u3002\u5b83\u4eec\u5206\u522b\u88ab\u79f0\u4e3a\u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u548c\u7b2c\u4e8c\u9636\u6bb5\u8def\u5f84\u3002 \u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u8def\u5f84 \u809d\u810f\u89e3\u6bd2\u7b2c\u4e00\u9636\u6bb5\u662f\u5bf9\u6297\u6bd2\u7d20\u7684\u7b2c\u4e00\u9053\u9632\u7ebf\uff0c\u7531\u4e00\u7ec4\u79f0\u4e3a\u7ec6\u80de\u8272\u7d20 P450 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