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\u7b80\u5355\u6765\u8bf4\uff0c\u6240\u6709\u5b69\u5b50\uff08\u6210\u4eba\u4e5f\u662f\uff09\u90fd\u5e94\u8be5\u6444\u53d6\u5404\u79cd\u5305\u62ec\u65b0\u9c9c\u852c\u679c\u3001\u5168\u8c37\u7c7b\u548c\u7cbe\u7626\u86cb\u767d\u8d28\u7684\u5168\u98df\u3002\u7cdf\u7cd5\u7684\u662f\uff0c\u8fd9\u4e9b\u98df\u7269\u901a\u5e38\u90fd\u662f\u6311\u98df\u8005\u4e0d\u559c\u6b22\u7684\u98df\u7269\u3002\u7f3a\u5c11\u4e86\u65b0\u9c9c\u7684\u852c\u83dc\u548c\u6c34\u679c<\/a>\u3001\u672a\u7ecf\u52a0\u5de5\u7684\u8089\u54c1\u548c\u5168\u8c37\u7c7b\u98df\u54c1\uff0c\u5b69\u5b50\u5f88\u96be\u62e5\u6709\u8eab\u4f53\u6210\u957f\u6240\u9700\u8981\u7684\u9002\u5f53\u7ea4\u7ef4\u3001\u86cb\u767d\u8d28\u548c\u7ef4\u751f\u7d20\u3002<\/p>\n

\u6311\u98df\u7814\u7a76<\/h2>\n

\u4e3a\u4e86\u7406\u89e3\u6311\u98df\u7684\u91cd\u8981\u5f71\u54cd\uff0c\u57c3\u6587\u90e1\u4eb2\u5b50\u7eb5\u5411\u7814\u7a76\u961f\u5217 ( Avon Longitudinal Study of Parents and Children Cohort, ALSPAC ) \u63a2\u8ba8\u4e86\u6311\u98df\u5982\u4f55\u5f71\u54cd 2 \u81f3 7.5 \u5c81\u513f\u7ae5\u7684\u8425\u517b\u72b6\u51b5\u3002\u7814\u7a76\u900f\u8fc7\u996e\u98df\u65e5\u5fd7\u4e0e\u95ee\u5377\uff0c\u8bb0\u5f55\u513f\u7ae5\u5728\u8fde\u7eed\u4e09\u5929\u5185\uff08\u4e24\u4e2a\u5e73\u65e5\u4e0e\u4e00\u4e2a\u5468\u672b\u65e5\uff09\u6444\u53d6\u7684\u6240\u6709\u5e38\u91cf\u8425\u517b\u7d20\u3001\u5fae\u91cf\u8425\u517b\u7d20\u53ca\u70ed\u91cf\uff0c\u5e76\u5c06\u8fd9\u4e9b\u6570\u636e\u4e0e\u82f1\u56fd\u81b3\u98df\u6307\u5357\u8fdb\u884c\u6bd4\u8f83\u5206\u6790\u3002<\/p>\n

\u7ed3\u679c\u663e\u793a\uff0c\u591a\u6570\u513f\u7ae5\u7684\u70ed\u91cf\u4e0e\u78b3\u6c34\u5316\u5408\u7269\u6444\u53d6\u5145\u8db3\uff0c\u4f46\u6311\u98df\u513f\u7ae5\u5f80\u5f80\u6444\u53d6\u8f83\u5c11\u7684\u86cb\u767d\u8d28\uff0c\u4e14\u5173\u952e\u5fae\u91cf\u8425\u517b\u7d20\u2014\u2014\u5c24\u5176\u94c1\u3001\u950c\u4e0e\u80e1\u841d\u535c\u7d20\u2014\u2014\u663e\u8457\u504f\u4f4e\u3002\u8fd9\u4e3b\u8981\u662f\u56e0\u4e3a\u6311\u98df\u513f\u7ae5\u7684\u8089\u7c7b\u3001\u852c\u83dc\u4e0e\u6c34\u679c\u6444\u53d6\u4e0d\u8db3\uff0c\u540c\u65f6\u504f\u597d\u9ad8\u7cd6\u98df\u54c1\u4e0e\u996e\u6599\u3002\u867d\u7136\u6574\u4f53\u8425\u517b\u7f3a\u4e4f\u5c1a\u672a\u8fbe\u4e25\u91cd\u7a0b\u5ea6\uff0c\u4f46\u6311\u98df\u513f\u7ae5\u4ecd\u8f83\u5bb9\u6613\u4f4e\u4e8e\u5efa\u8bae\u6444\u53d6\u91cf\u3002<\/p>\n

\u6311\u98df\u8005\u7684\u5bf9\u4ed8\u7b56\u7565 <\/strong><\/h2>\n

\u73b0\u5728\uff0c\u60a8\u7684\u6000\u7591\u5df2\u7ecf\u83b7\u5f97\u89e3\u7b54\uff1a\u6311\u98df\u8005\u5e76\u4e0d\u7b97\u5065\u5eb7\uff0c\u800c\u4e14\u4e5f\u662f\u4e0d\u7406\u60f3\u7684\u884c\u4e3a\u3002\u90a3\u4e0b\u4e00\u6b65\u8be5\u600e\u4e48\u505a\u5462\uff1f\u8fd8\u597d\uff0c\u6311\u98df\u8005\u5e76\u4e0d\u9700\u8981\u6c38\u8fdc\u6311\u98df\u3002\u751f\u6d3b\u4e2d\u6709\u8bb8\u591a\u7b56\u7565\u80fd\u5e2e\u52a9\u6311\u98df\u8005\u6269\u5c55\u4ed6\u4eec\u7684\u996e\u98df\u559c\u597d\u2014\u2014\u91cd\u70b9\u662f\uff0c\u6211\u4eec\u5fc5\u987b\u8981\u5bf9\u7684\u60c5\u51b5\u4e0b\u4f7f\u7528\u6b63\u786e\u7684\u7b56\u7565\u3002<\/p>\n

\u7814\u7a76\u5efa\u8bae\uff0c\u6211\u4eec\u80fd\u900f\u8fc7\u53cd\u8986\u63a5\u89e6\u6765\u514b\u670d\u5bf9\u4e8e\u67d0\u4e9b\u98df\u7269\u7684\u538c\u6076\u611f\u3002\u8fd9\u8868\u793a\u6311\u98df\u8005\u6709\u53ef\u80fd\u5728\u5c1d\u8bd5\u51e0\u6b21\u4ed6\u4eec\u4e0d\u559c\u6b22\u7684\u98df\u7269\u540e\u6162\u6162\u559c\u6b22\u4e0a\u8fd9\u4e9b\u98df\u7269\u3002\u5047\u8bbe\u60a8\u7684\u5b69\u5b50\u8ba8\u538c\u897f\u7ea2\u67ff\uff08\u756a\u8304\uff09\uff0c\u82e5\u60a8\u7528\u4e0d\u4e00\u6837\u7684\u6599\u7406\u65b9\u5f0f\u7ed9\u4ed6\u4eec\u8db3\u591f\u7684\u897f\u7ea2\u67ff\uff08\u756a\u8304\uff09\uff0c\u4ed6\u4eec\u6709\u53ef\u80fd\u4f1a\u6e10\u6e10\u7684\u7231\u4e0a\u897f\u7ea2\u67ff\uff08\u756a\u8304\uff09\uff09\u3002\u6709\u4e9b\u5bf9\u4e8e\u98df\u7269\u7684\u559c\u597d\u662f\u53ef\u4ee5\u900f\u8fc7\u540e\u5929\u57f9\u517b\u800c\u6210\u7684\uff0c\u6211\u4eec\u53ea\u9700\u8981\u5e2e\u52a9\u5b69\u5b50\u201c\u7ec3\u4e60\u201d\u559c\u6b22\u4e0a\u67d0\u4e9b\u98df\u7269\u3002<\/p>\n

\u5b69\u5b50\u559c\u6b22\u6548\u4eff\u6a21\u8303\u3002\u5982\u679c\u60a8\u81ea\u5df1\u4e0d\u559c\u6b22\u852c\u83dc\uff0c\u90a3\u4e48\u60a8\u7684\u5b69\u5b50\u53ef\u80fd\u4e5f\u4e0d\u5403\u852c\u83dc\u3002\u4e0d\u8981\u4e3a\u60a8\u7684\u5b69\u5b50\u51c6\u5907\u4e0d\u4e00\u6837\u7684\u6599\u7406\u3002\u5230\u4e86\u5403\u996d\u65f6\u95f4\uff0c\u5927\u5bb6\u90fd\u5e94\u8be5\u5750\u4e0b\u6765\u4eab\u7528\u4e00\u6837\u7684\u7f8e\u98df\u3002\u4ee5\u8eab\u4f5c\u5219\uff0c\u8ba9\u5b69\u5b50\u770b\u5230\u60a8\u559c\u6b22\u5404\u79cd\u7279\u522b\u7684\u98df\u7269\u3002\u8fd8\u6709\uff0c\u5229\u7528\u4e0d\u540c\u7684\u6599\u7406\u65b9\u5f0f\u5e2e\u52a9\u5b69\u5b50\u5c1d\u8bd5\u65b0\u7684\u98df\u7269\uff1b\u82e5\u4ed6\u4eec\u8ba8\u538c\u751f\u7684\u80e1\u841d\u535c\uff0c\u8bd5\u8bd5\u84b8\u716e\u7684\u80e1\u841d\u535c\u3002 \uff08\u60a8\u62c5\u5fc3\u4e0d\u540c\u7684\u6599\u7406\u65b9\u5f0f\u4f1a\u5f71\u54cd\u98df\u7269\u7684\u517b\u5206\u5417\uff1f\u7acb\u5373\u9605\u8bfb\u70f9\u996a\u5bf9\u852c\u83dc\u7684\u5f71\u54cd\uff01\u7acb\u5373\u9605\u8bfb\u70f9\u996a\u5bf9\u852c\u83dc\u7684\u5f71\u54cd<\/a>\uff01)<\/p>\n

\u8ba9\u6311\u98df\u513f\u7ae5\u987a\u5229\u8fdb\u98df\u7684\u516d\u79cd\u8bc0\u7a8d <\/strong><\/h2>\n

\u82e5\u60a8\u60f3\u77e5\u9053\u5982\u4f55\u7528\u7b80\u5355\u53ef\u884c\u7684\u65b9\u5f0f\u8ba9\u6311\u98df\u7684\u5b69\u5b50\u4e56\u4e56\u8fdb\u98df\uff0c\u90a3\u60a8\u5c31\u6765\u5bf9\u5730\u65b9\u4e86\uff01\u8bd5\u8bd5\u4ee5\u4e0b\u516d\u79cd\u8bc0\u7a8d\uff01<\/p>\n

    \n
  1. \u7ed9\u5b69\u5b50\u51e0\u9879\u9009\u62e9\uff1a<\/strong>\u5728\u5b69\u5b50\u6210\u957f\u548c\u53d1\u5c55\u7684\u8fc7\u7a0b\u4e2d\uff0c\u4ed6\u4eec\u7684\u611f\u5b98\u548c\u81ea\u6211\u610f\u8bc6\u4e5f\u4e0d\u65ad\u5730\u5728\u6210\u957f\u3002\u56e0\u6b64\uff0c\u5b69\u5b50\u5728\u98df\u7269\u7684\u9009\u62e9\u4e0a\u53ef\u80fd\u4e5f\u4f1a\u6709\u8d8a\u6765\u8d8a\u591a\u7684\u610f\u89c1\u3002\u5f53\u7136\uff0c\u4e00\u4e2a\u56db\u5c81\u7684\u5c0f\u7537\u5b69\u4e0d\u8be5\u5b8c\u5168\u51b3\u5b9a\u4ed6\u7684\u996e\u98df\u4e60\u60ef\uff1b\u4e0d\u8fc7\uff0c\u60a8\u80fd\u5728\u7528\u4e3a\u4ed6\u63d0\u4f9b\u9009\u62e9\u7684\u65b9\u5f0f\u6765\u6ee1\u8db3\u4ed6\u5bf9\u98df\u7269\u7684\u611f\u5b98\u548c\u81ea\u6211\u610f\u8bc6\u3002\u5982\u679c\u60a8\u65e0\u6cd5\u8ba9\u60a8\u7684\u5b69\u5b50\u7231\u4e0a\u80e1\u841d\u535c\uff0c\u95ee\u9898\u53ef\u80fd\u4e0d\u6765\u81ea\u4e8e\u80e1\u841d\u535c\uff0c\u95ee\u9898\u53ef\u80fd\u5728\u5b69\u5b50\u6b63\u5728\u53d1\u5c55\u7684\u81ea\u6211\u610f\u8bc6\u548c\u63a7\u5236\u6743\u4e0a\u3002\u4e0e\u5176\u4e13\u6ce8\u5728\u5f3a\u8feb\u4ed6\u4eec\u5403\u4e0b\u80e1\u841d\u535c\u4e0a\uff0c\u4e0d\u5982\u4e3a\u4ed6\u4eec\u63d0\u4f9b\u4e24\u79cd\u5065\u5eb7\u7684\u9009\u62e9\uff0c\u8ba9\u4ed6\u4eec\u9009\u51fa\u81ea\u5df1\u7684\u559c\u597d\u3002 \u201c\u4f60\u4eca\u665a\u60f3\u5403\u80e1\u841d\u535c\u8fd8\u662f\u56db\u5b63\u8c46\uff1f\u201d \u6709\u65f6\u5019\u4e00\u4e2a\u50cf\u8fd9\u6837\u7b80\u5355\u7684\u95ee\u9898\u5c31\u80fd\u89e3\u51b3\u60a8\u7684\u56f0\u6270\u3002<\/li>\n
  2. \u4e0d\u8981\u51c6\u5907\u4e0d\u4e00\u6837\u7684\u9910\u98df\uff1a<\/strong> \u6b63\u5982\u4e0a\u8ff0\uff0c\u5b69\u5b50\u559c\u6b22\u4ee5\u7236\u6bcd\u4f5c\u4e3a\u4ed6\u4eec\u7684\u6a21\u8303\uff0c\u5e76\u6548\u4eff\u7236\u6bcd\u7684\u884c\u4e3a\u3002\u5982\u679c\u5b69\u5b50\u770b\u89c1\u60a8\u6240\u51c6\u5907\u7684\u6599\u7406\u540e\u8981\u6c42\u5176\u4ed6\u7684\u9910\u70b9\uff0c\u6211\u4eec\u5efa\u8bae\u60a8\u4e0d\u8981\u8f7b\u6613\u59a5\u534f\u2014\u2014\u8ba9\u5927\u5bb6\u5750\u4e0b\u6765\u4e00\u8d77\u4eab\u7528\u60a8\u6240\u51c6\u5907\u7684\u9910\u70b9\u3002\u5728\u4ed6\u4eec\u770b\u89c1\u60a8\u4eab\u7528\u7f8e\u98df\u4e4b\u9645\uff0c\u60a8\u6311\u98df\u7684\u5b69\u5b50\u6709\u53ef\u80fd\u51b3\u5b9a\u548c\u60a8\u4e00\u6837\uff0c\u4e00\u540c\u4eab\u7528\u6599\u7406\uff01\u5728\u51c6\u5907\u9910\u70b9\u65f6\uff0c\u522b\u5fd8\u4e86\u4e4b\u524d\u6240\u63d0\u5230\u7684\u6599\u7406\u9009\u62e9\uff08\u4f8b\u5982\uff1a\u7897\u8c46\u6216\u82b1\u6930\u83dc\/\u897f\u5170\u82b1\uff09\uff0c\u4e0d\u8fc7\uff0c\u4e0d\u8981\u8f7b\u6613\u8ba9\u5b69\u5b50\u9009\u62e9\u8fd9\u4e9b\u9910\u70b9\u4ee5\u5916\u7684\u6599\u7406\u9009\u62e9\u3002<\/li>\n
  3. \u5efa\u7acb\u5e76\u7ef4\u6301\u89c4\u5f8b\u7684\u996e\u98df\u4e60\u60ef\uff1a <\/strong>\u5b69\u5b50\u5728\u89c4\u5f8b\u7684\u73af\u5883\u4e0b\u80fd\u62e5\u6709\u6700\u597d\u7684\u8868\u73b0\uff0c\u800c\u7528\u9910\u65f6\u95f4\u4e5f\u4e0d\u4f8b\u5916\u3002\u8bb8\u591a\u4eba\u6210\u4e3a\u6311\u98df\u8005\u7684\u539f\u56e0\u5c31\u662f\u5728\u6210\u957f\u8fc7\u7a0b\u4e2d\u6301\u7eed\u907f\u514d\u5c1d\u8bd5\u4e0d\u719f\u6089\u7684\u98df\u7269\u3002\u5c1d\u8bd5\u65b0\u7684\u98df\u7269\u548c\u62d3\u5c55\u996e\u98df\u4e60\u60ef\u5df2\u7ecf\u4e3a\u5e74\u5e7c\u7684\u5b69\u5b50\u5e26\u6765\u8db3\u591f\u7684\u538b\u529b\u4e86\uff0c\u6240\u4ee5\u6211\u4eec\u5e94\u8be5\u8bd5\u7740\u8ba9\u5176\u5b83\u6784\u6210\u996e\u98df\u4f53\u9a8c\u7684\u5143\u7d20\u4fdd\u6301\u4e00\u81f4\uff0c\u5e76\u4e14\u907f\u514d\u4ed6\u4eec\u65e0\u6cd5\u9884\u77e5\u7684\u72b6\u51b5\u3002\u6bcf\u5929\u7ef4\u6301\u4e00\u81f4\u7684\u7528\u9910\u65f6\u95f4\u3002\u7ef4\u6301\u60a8\u548c\u5b69\u5b50\u7528\u9910\u65f6\u95f4\u53ca\u5730\u70b9\u7684\u4e00\u81f4\u6027\u3002<\/li>\n
  4. \u4fdd\u6301\u8010\u5fc3\uff0c\u4e0d\u8981\u5f3a\u8feb\u8fdb\u98df\uff1a<\/strong> \u5982\u679c\u60a8\u7684\u5b69\u5b50\u62d2\u5403\u897f\u5170\u82b1\uff08\u82b1\u6930\u83dc\uff09\uff0c\u4ed6\u4eec\u5e94\u8be5\u4e0d\u53ef\u80fd\u7a81\u7136\u5728\u67d0\u4e00\u5929\u7231\u4e0a\u5b83\u3002\u7ec3\u4e60\u559c\u6b22\u4e0a\u98df\u7269\u7684\u53e3\u5473\u9700\u8981\u65f6\u95f4\u548c\u53cd\u8986\u7684\u63a5\u89e6\uff0c\u8fd9\u4ee3\u8868\u60a8\u7684\u5b69\u5b50\u53ef\u80fd\u5728\u5480\u56bc\u4e00\u6735\u897f\u5170\u82b1\uff08\u82b1\u6930\u83dc\uff09\u540e\u628a\u5b83\u4ece\u53e3\u4e2d\u5410\u51fa\u6765\u2014\u2014\u6ca1\u6709\u5173\u7cfb\uff01\u7ed9\u6311\u98df\u7684\u5b69\u5b50\u9002\u5e94\u65b0\u98df\u7269\u7684\u65f6\u95f4\uff0c\u5e76\u6301\u7eed\u7ed9\u4e88\u4ed6\u4eec\u5c1d\u8bd5\u65b0\u98df\u7269\u7684\u673a\u4f1a\u3002\u7ed9\u6311\u98df\u7684\u5b69\u5b50\u9002\u5e94\u65b0\u98df\u7269\u7684\u65f6\u95f4\uff0c\u5e76\u6301\u7eed\u7ed9\u4e88\u4ed6\u4eec\u5c1d\u8bd5\u65b0\u98df\u7269\u7684\u673a\u4f1a\u3002<\/li>\n
  5. \u98df\u6750\u548c\u70f9\u996a\u65b9\u5f0f\u7684\u6df7\u642d\uff1a<\/strong> \u867d\u7136\u8ba9\u5b69\u5b50\u53cd\u8986\u63a5\u89e6\u98df\u6750\u662f\u8ba9\u4ed6\u4eec\u559c\u6b22\u4e0a\u98df\u7269\u7684\u65b9\u5f0f\u4e4b\u4e00\uff0c\u8fd9\u5e76\u4e0d\u8868\u793a\u60a8\u5e94\u8be5\u5728\u5b69\u5b50\u559c\u6b22\u4e0a\u67d0\u79cd\u98df\u7269\u4e4b\u524d\u4e0d\u65ad\u70f9\u716e\u76f8\u540c\u7684\u6599\u7406\u3002\u5982\u679c\u60a8\u7684\u5b69\u5b50\u8ba8\u538c\u751f\u7684\u751c\u6912\uff0c\u4e0d\u8981\u5728\u6bcf\u5929\u7684\u665a\u9910\u65f6\u95f4\u5f3a\u8feb\u4ed6\u4eec\u5403\u4e0b\u751f\u751c\u6912\u3002\u522b\u5fd8\u4e86\uff0c\u67d0\u4e9b\u5bf9\u98df\u7269\u7684\u538c\u6076\u6709\u53ef\u80fd\u662f\u56e0\u4e3a\u98df\u7528\u8005\u5bf9\u98df\u7269\u8d28\u611f\u7684\u654f\u611f\u5ea6\uff0c\u4e0d\u4eff\u8bd5\u8bd5\u70e7\u70e4\u6216\u70ed\u7092\u7684\u65b9\u5f0f\u6765\u6599\u7406\u751c\u6912\u3002\u8fd8\u6709\uff0c\u6211\u4eec\u90fd\u77e5\u9053\u751c\u6912\u4e0d\u662f\u4e16\u754c\u4e0a\u552f\u4e00\u7684\u5065\u5eb7\u98df\u6750\u3002\u6709\u65f6\u5019\u53ef\u4ee5\u6362\u6362\u53e3\u5473\uff0c\u4e0d\u9700\u8981\u62d8\u6ce5\u4e8e\u6599\u7406\u751c\u6912\u4e0a\uff01\u4e3a\u5b69\u5b50\u63d0\u4f9b\u5176\u5b83\u3002\u4f8b\u5982\u80e1\u841d\u535c\u3001\u897f\u5170\u82b1\uff08\u82b1\u6930\u83dc\uff09\u6216\u56db\u5b63\u8c46\u7b49\u7b49\u7684\u8425\u517b\u98df\u7269\u3002<\/li>\n
  6. \u8bd5\u8bd5\u5582\u98df\u7597\u6cd5\uff1a <\/strong>\u5982\u679c\u60a8\u7684\u5b69\u5b50\u62e5\u6709\u611f\u5b98\u996e\u98df\u538c\u6076\u4e14\u6781\u5ea6\u6311\u98df\uff0c\u60a8\u53ef\u4ee5\u9009\u62e9\u8003\u8651\u996e\u98df\u7597\u6cd5\u3002\u5bf9\u8ba8\u538c\u7684\u98df\u7269\u62e5\u6709\u5f3a\u70c8\u751f\u7406\u53cd\u5e94\uff08\u4f8b\u5982\u5e72\u5455\u3001\u5e72\u54b3\u3001\u553e\u5410\u6216\u564e\u545b\u7b49\uff09\u884c\u4e3a\u7684\u5b69\u5b50\u4eec\uff0c\u5582\u98df\u7597\u6cd5\u53ef\u80fd\u7279\u522b\u6709\u5e2e\u52a9\u3002\u867d\u7136\u8fd9\u4e0d\u5e94\u8be5\u662f\u60a8\u7684\u9996\u9009\u89e3\u51b3\u65b9\u5f0f\uff0c\u5728\u7528\u5c3d\u5404\u79cd\u65b9\u5f0f\u4e4b\u540e\uff0c\u5582\u98df\u7597\u6cd5\u53ef\u80fd\u53ef\u4ee5\u5e2e\u52a9\u60a8\u7684\u5b69\u5b50\u4eab\u7528\u996e\u98df\u3002<\/li>\n<\/ol>\n
    \n

    https:\/\/pubmed.ncbi.nlm.nih.gov\/30392488\/<\/a><\/p>\n

    https:\/\/pubmed.ncbi.nlm.nih.gov\/27935522\/<\/a><\/p>\n<\/div><\/div><\/div><\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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